Abstract: The present invention includes compounds having structural formula (I), or pharmaceutically acceptable salts, solvate, and/or ester thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of enhancing the sweet taste of ingestible compositions. Furthermore, the present invention provides methods for preparing the compounds.

Abstract: The present invention provides polypeptide modulators of complement activity, including cyclic polypeptide modulators. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: The present invention includes compounds having structural formula (I), or salts or solvates thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of enhancing the sweet taste of compositions.

Abstract: The invention relates to synthetic plant miRNA precursor molecules that are resistant to processing in plants but functional in plant pests. The invention further relates to methods for using the synthetic plant miRNA precursor molecules to protect plants against pests.

Abstract: The present invention includes methods/processes and intermediates for preparing compounds having structural Formula (I): wherein X is alkyl, substituted alkyl, alkenyl, substituted alkenyl, heteroalkyl, substituted heteroalkyl, heteroalkenyl, or substituted heteroalkenyl.

Abstract: The invention relates to synthetic miRNA precursor molecules and methods for the use of the miRNA precursor molecules in modulating the expression of target polynucleotides

Abstract: There discloses a ubiquitous energy network for optimum utilization of energy, which includes nodes connected by an interconnected network architecture of virtual pipelines transferring a ubiquitous energy flow, with the ubiquitous energy flow being transferred among the nodes bi-directionally. The node includes a system energy efficiency controller, and at least one of other nodes, an energy generation device, an energy storage device, an energy utilization device, and an energy regeneration device connected to the controller. The controller controls the input and output of the ubiquitous energy flow of the at least one of the other nodes, the energy generation device, the energy storage device, the energy utilization device, the energy regeneration device. Furthermore, the node, an access terminal, a virtual tag, and the virtual pipeline of the ubiquitous energy network, and a server and method for providing energy transaction and service by the ubiquitous energy network are disclosed.

Abstract: A method for calibrating a laser deflection device in a reflected light device of a microscope of a laser microdissection system having a digital image capturing unit comprising an image evaluation module includes generating a laser beam; guiding the laser beam through a microscope objective; directing the laser beam to a position defined by actuation signals; placing a calibration object in the object plane of the microscope objective; actuating the laser deflection device using first actuation signals and first calibration values, making at least one calibration mark on the calibration object; capturing an image of the calibration object by the digital image capturing unit; determining actual position values for the at least one calibration mark: and determining second calibration values based on a relationship between the default position values and the actual position values.

Abstract: The present invention includes methods/processes and intermediates for preparing compounds having structural Formula (I): wherein X is alkyl, substituted alkyl, alkenyl, substituted alkenyl, heteroalkyl, substituted heteroalkyl, heteroalkenyl, or substituted heteroalkenyl.

Abstract: A bi-polarized broadband annular radiation unit, for being installed on a metal reflective plate thus constituting a communication antenna and defining an annular construction by two pairs of orthogonally polarized dipoles, includes two pairs of orthogonally polarized dipoles, each dipole comprising two symmetrical unit arms of a single line sheet shape, one end of a unit arm being facing to a corresponding end of the other unit arm, and a distal end of each unit arm of at least one pair of dipoles is provided with a loading line; and a plurality of balun arms feeding power to and supporting respective dipoles, each balun arm including two parallel balun lines, and the top ends of the two balun lines being connected with corresponding ends of the two unit arms of a corresponding dipole. Each unit arm and the balun line and/or loading line connected to the same unit arm are made by sheet metal stamping forming process or casting process.

Abstract: A system energy efficiency controller connected (105) to at least one of an energy generation device (101), an energy storage device (102), an energy utilization device (103) and an energy regeneration device (104) is disclosed for enabling energy utilization. Said system energy efficiency controller (105) cooperatively controls the input and output of a ubiquitous energy flow of at least one of the energy generation device (101), the energy storage device (102), the energy utilization device (103) and the energy regeneration device (104). Said ubiquitous energy flow includes at least one of an energy flow, a material flow, and an information flow. Also disclosed are an energy efficiency gain device, an energy efficiency matching station and a smart energy service system, which are connected with the controller (105). The present invention optimizes the entire process of energy utilization using the system energy efficiency controller (105), thus improving the system energy efficiency.

Abstract: The present invention provides modulators of complement activity. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: The present invention provides screening methods for identifying modifiers of chemosensory receptors and their ligands, e.g., by determining whether a test entity is suitable to interact with one or more interacting sites within the Venus flytrap domains of the chemosensory receptors as well as modifiers capable of modulating chemosensory receptors and their ligands.

Abstract: This invention provides polypeptides that were identified as interacting with Vip3 toxin. This invention also provides a method of identifying agents that bind to Vip3 interacting polypeptides, which agents may act as insecticidal agent, cytotoxic agents and/or modulate the activity of Vip3 interacting polypeptides.

Abstract: A workflow to optimize a fracturing fluid for injection into a subterranean formation is provided. The workflow comprises measurement of fundamental properties and characteristics of reservoir rock and fluid, their interaction with fracturing fluid, computer-based models and laboratory performance testing to select preferred fracturing base fluid and additives package for use in fracturing/re-fracturing stimulation of specific shale formations to enhance hydrocarbon recovery.

Abstract: The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

Abstract: The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

Abstract: The present invention includes methods/processes and intermediates for preparing compounds having structural Formula (I): wherein X is alkyl, substituted alkyl, alkenyl, substituted alkenyl, heteroalkyl, substituted heteroalkyl, heteroalkenyl, or substituted heteroalkenyl.

Abstract: This invention provides a method to silence an endogenous target gene expression in plants by applying a specific dsRNA onto the exterior surface of a plant. Application, such as by spraying or brushing a plant with dsRNA is done without wounding the plant tissue and cells such as by mechanical-type wounding, particle bombardment or mechanical infection with viral vectors. The present invention enables the regulation of gene expression in plants. In some embodiments of the invention, the dsRNA is directed to an essential gene of a plant pathogen or pest, whereby the pathogen and/or pest damage is controlled, resulting in desired agronomic performance.

Abstract: The present invention includes compounds having structural formula (I), or pharmaceutically acceptable salts, solvate, and/or ester thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of enhancing the sweet taste of ingestible compositions. Furthermore, the present invention provides methods for preparing the compounds.