Abstract: Provided is 5-(3-chloro-4-fluorophenyl)-7-cyclopropyl-3-(2-(3-fluoro-3-methylazetidin-1-yl)-2-oxoethyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one and pharmaceutically acceptable salts thereof, and their uses in the treatment of psychiatric, neurological, and neurodevelopmental disorders, as well as diseases of the nervous system.

Abstract: There is disclosed: a wood adhesive composition comprising a protein and a poly(glycidyl ether); a method for using the wood adhesive composition to make a composite wood product; and composite wood products made using the wood adhesive composition.

Abstract: Exemplary methods and systems can be provided for resurfacing of skin that include formation of a plurality of small holes, e.g., having widths greater than about 0.2 mm and less than about 0.7 mm or 0.5 mm, using a mechanical apparatus. Compressive and/or tensile forces can then be applied to the treated region of skin as the damage heals to facilitate hole closure, and provide enhanced and/or directional shrinkage of the treated skin area.

Abstract: An image processing system is configured to identify features of the field in the image signals of the visual sensor system and, on the basis of the identified features, to create a first path for the vehicle. A navigation unit is configured to determine the position of a reference point on the vehicle. An electronic memory is configured to store waypoints for a second path of the vehicle to be driven. A path calculator is configured to convert the first and/or second path into a common coordinate system. A fusion unit is configured to fuse the first path and the second path and, based on the fused path thus obtained, to provide a signal to a steering control system to steer the vehicle along the fused path and/or to store waypoints for positions passed by the vehicle calculated on the basis of the fused path in the memory.

Abstract: A wireless microphone system may be configured to compensate for a radio frequency (RF) loss incurred in a wired communication path. The system may comprise a receiver configured to receive an downlink RF signal from a wireless microphone, and a transmission line accessory configured to receive an uplink test signal. The RF test signal may be generated from an RF source and may be measured by the transmission line accessory to determine configuration information for an adjustable RF gain circuit.

Abstract: Techniques are described herein that are capable of providing a recommendation of an admin change (i.e., an admin change recommendation) in an enterprise. A type of intended admin change that an administrator is to perform with regard to an enterprise is determined. The type is cross-referenced with information indicating admin changes made by administrator(s) in environment(s) of enterprise(s) and values of metrics resulting therefrom to identify subsets of the information to which the type corresponds. A causal relationship is inferred between admin change(s) made after an admin change of the type and an increase in value(s) of metric(s) that are indicated by information in the subsets. A recommended admin change is recommended to be performed by the administrator based at least in part on a causal relationship between the recommended admin change and an increase in at least one of the value(s) of at least one of the respective metric(s).

Abstract: A roofing system has metal roofing shingles that have formed side lap features that are configured to facilitate alignment of adjacent side lapped metal roofing shingles of a shingle installation along a roofing structure and that couple the metal roofing shingles together and form seals and seams along their side lapped peripheral edges. The metal roofing shingles also can have alignment features that cooperate to align shingles in one course with shingles in a next lower course within their headlap regions. The roofing system also has standing seam features configured to couple to the metal roofing shingles to cover the formed seams.

Abstract: A wireless microphone system comprises system equipment (for example, rack-mounted equipment including receivers/transceivers, distribution amplifier), one or more transmission line accessories, and a transmission line network connecting the accessories with the system equipment. The transmission line accessory compensates for downlink RF losses on transmission lines between accessories and between an accessory and system equipment. Compensation parameters for the transmission line accessory is determined by the system equipment by generating an uplink RF test signal by an RF source at the system equipment. The RF source may be varied over a plurality of frequencies to determine the compensation parameters over the plurality of frequencies. The system equipment subsequently instructs the transmission line accessory to configure an adjustable RF gain circuit (and also possibly a compensation filter) accordingly.

Abstract: Roofing panels with water shedding features may be installed on the roof of a house or other structure in lieu of or as an underlayment for traditional roofing materials. The water shedding features can be built into a base of the roofing panels, as part of a frame for the roofing panels, or formed as part of a waterproofing layer applied to the base of the roofing panels, or which can be configured as a roofing panel. The roofing panels also can be installed in overlapping courses along a roof with water shedding features applied thereto or incorporated along one or more peripheral edges. The water shedding features of adjacent roofing panels will collect and divert water away from the upper surfaces and/or away from headlap and/or sidelap joints defined between the roofing panels.

Abstract: A roofing system has metal shingles that have formed side lap features that are configured to facilitate alignment of adjacent side lapped metal shingles of a shingle installation along a roofing structure and that couple the metal shingles together and form seals along their side lapped peripheral edges. The metal shingles also can have alignment features that cooperate to align shingles in one course with shingles in a next lower course within their headlap regions.

Abstract: Compounds that selectively negatively modulate NMDA receptors containing an NR1/NR2B subunit, pharmaceutical compositions comprising the compounds, and methods of treating a disease using the compounds are disclosed.

Abstract: Disclosed herein, in part, are heteroaromatic compounds and methods of use in treating neuropsychiatric disorders, e.g., schizophrenia and major depressive disorder. Pharmaceutical compositions and methods of making heteroaromatic compounds are provided. The compounds are contemplated modulate the NMDA receptor.

Abstract: The present invention provides improved sorbents and corresponding device(s) and uses thereof for the capture of contaminants from breathable air in an enclosed habitable space. The sorbents are capable of rapid and high adsorption of moisture, carbon dioxide and other contaminants from forced air and provide quantitative release of the sorbates when exposed to vacuum. The sorbents may be included in air treatment systems, such as portable life support systems (trace contaminant control systems), to maintain a breathable atmosphere in spacecraft, watercraft, or landcraft having enclosed habitable spaces and also in space suits.

Abstract: The integration of news about members of a group into symmetrical group communications is described. Group members are delivered news items and information regarding members of the group, and are able to communicate with other members of the group in response to the news items. One embodiment dynamically generates aggregated RSS news feeds for a group of people or entities and correlates that aggregated data with biographical information, audio, and video media to provide rich information about the relevant parties to the news story. The embodiment also provides the capability of transmitting email or other electronic messages to the parties in the news story to facilitate two-way communication while maintaining the group members' privacy and anonymity.

Abstract: The present disclosure relates to N-alkylaryl-5-oxyaryl-octadihydrocyclopent[c]pyrrole negative allosteric modulators of NR2B receptors useful in the treatment of neurological diseases having the Formula I: where R1, R2, L1, L2, X, Y, and Y? are described therein.

Abstract: A high-speed, cold laminating system includes a lamination unit for inline use connected with a paper feeder supplying at least 30 ppm. The lamination unit further includes a set of unheated motor-driven laminating pressure rollers along a laminating path, and a cutter between the rollers and an exit. A diverter gate passes the paper sheets to the laminating path or to the exit without passing along the laminating path. The system includes a controller to control the motor, the diverter gate, and functions of the lamination unit. The controller is programmed to control the motor to pause the pressure rollers with a leading sheet therein while a subsequent sheet moves toward the pressure rollers so a laminated spacing distance between a trailing edge of the leading sheet and a leading edge of the subsequent sheet to equal a prescribed spacing distance.

Abstract: Thermoformed polymeric foam articles and methods of forming the same are described. In some embodiments, thermoformed articles are produced from multi-layer foamed sheet where the formed article has a density equal to or less than the precursor multi-layer sheet. One of the layers of the thermoformed article may be a polymer foam layer having a density reduction between 5% and 50% as compared to the solid polymer. Such polymer foam layers can be referred to as “medium density” or “high density” foams. Advantageously, the methods described herein are practical for commercial use and, for example, can be used to produce a variety of thermoformed articles suitable for use in many different applications.

Abstract: A PFAS-free fire foam concentrate composition comprising water, a plant-based protein, a surfactant, an alcohol, and a builder. The bio-based content of the PFAS-free fire foam is preferably 80% by weight or greater. There is also disclosed a process to produce the PFAS-free fire foam concentrate composition, and the application of the fire foam concentrate onto a Class A fire or Class B fire.