Patents by Inventor R. Lawrence

R. Lawrence has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Urea antagonists of P2Yreceptor useful in the treatment of thrombotic conditions
    Patent number: 7674828
    Abstract: The present invention provides novel pyridyl or phenyl ureas and analogues thereof, which are selective inhibitors of the human P2Y1 receptor. The invention also provides for various pharmaceutical compositions of the same and methods for treating diseases responsive to modulation of P2Y1 receptor activity.
    Type: Grant
    Filed: May 8, 2008
    Date of Patent: March 9, 2010
    Assignee: Bristol-Myers Squibb Company
    Inventors: Hannguang J. Chao, Huji Tuerdi, Timothy F. Herpin, Jacques Y. Roberge, Yalei Liu, Michael R. Lawrence, Robert P. Rehfuss, Charles G. Clark, Jennifer X. Qiao, Timur Gungor, Patrick Y. S. Lam, Tammy C. Wang, Rejean Ruel, Alexandre L'Heureux, Carl Thibeault, Gilles Bouthillier, Dora M. Schnur
  • Integrated physiological sensor apparatus and system
    Publication number: 20100049007
    Abstract: A physiological sensor apparatus, system and method for determining a physiological characteristic, comprising providing at least one physiological sensor that is adapted to measure at least one physiological characteristic at a target measurement site on a subject's body, heating an extended tissue region on the subject's body, whereby blood perfusion of the tissue region is enhanced, and measuring at least one physiological characteristic at the target measurement site with the physiological sensor during or within a predetermined period after heating the extended tissue region. In one embodiment, the sensor system includes at least one temperature algorithm that is adapted to adjust the heat applied to the extended tissue region based on the body's response to the heat stimuli.
    Type: Application
    Filed: August 20, 2008
    Publication date: February 25, 2010
    Inventors: Bernhard B. Sterling, Andrew R. Lawrence, Gregory I. Voss, James M. Perry, Rankin A. Clinton, III
  • Non-invasive method and system for determining physiological characteristics
    Publication number: 20100049023
    Abstract: A non-invasive method of determining a physiological characteristic, comprising providing at least one physiological sensor that is adapted to measure at least one physiological characteristic at a target measurement site on a subject's body, heating an extended tissue region on the subject's body, whereby blood perfusion of the tissue region is enhanced, and measuring at least one physiological characteristic with the physiological sensor during or within a predetermined period after heating the extended tissue region.
    Type: Application
    Filed: August 20, 2008
    Publication date: February 25, 2010
    Inventors: Bernhard B. Sterling, Andrew R. Lawrence, Gregory I. Voss, James M. Perry, Rankin A. Clinton, III
  • Systems and methods for generating multiple implicit search queries
    Patent number: 7664734
    Abstract: Systems and methods for generating multiple implicit search queries are described. In one described system, a query system receives a user context attribute and generates a plurality of implicit search queries based at least in part on the user context attribute. The query system then receives result sets associated with each of the plurality of implicit search queries and combines the results for display to a user.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: February 16, 2010
    Assignee: Google Inc.
    Inventors: Stephen R. Lawrence, Niniane Wang
  • METHODS AND APPARATUS TO VERIFY CONSUMPTION OF PROGRAMMING CONTENT
    Publication number: 20100037250
    Abstract: Methods and apparatus to verify consumption of content are described herein. In an example method, a content library is generated within a data structure. The content library includes at least one content identifier associated with programming content. The programming content is insertable into content stream. A content stream including content for broadcasting on a broadcast device is received. To verify consumption of the programming content, a broadcast content identifier associated with the content for broadcasting is compared to the at least one content identifier of the content library.
    Type: Application
    Filed: October 16, 2009
    Publication date: February 11, 2010
    Inventor: Bradley R. Lawrence, III
  • Compression of structured documents
    Patent number: 7593949
    Abstract: Various embodiments are disclosed relating to a compression of documents. According to an example embodiment, a document may be compressed by replacing one or more language constructs in the document with a language-based replacement code. In addition, the document may be compressed by replacing one or more text strings in the document with a schema-based replacement code.
    Type: Grant
    Filed: January 9, 2006
    Date of Patent: September 22, 2009
    Assignee: Microsoft Corporation
    Inventors: Andrew P Begun, Thomas R Lawrence
  • Systems and methods of synchronizing indexes
    Patent number: 7581227
    Abstract: Systems and methods that synchronize indexes are described. In one embodiment, a first index on a first client can be provided, wherein the first index comprises a plurality of terms associated with a plurality of events, the events comprising client activity associated with an article, and the first index can be synchronized with a second index or a second client by sending events from the first client to the second client, wherein the first and second indexes index the same events. In another embodiment, an event is retrieved from a first client, wherein the event comprises event data, the event is sent to a second client, the event is received by the second client as a new event, the new event comprising event data, a new event ID is associated with the new event, the new event ID is indexed, and the new event is stored.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: August 25, 2009
    Assignee: Google Inc.
    Inventors: Stephen R. Lawrence, Omar Habib Khan
  • Methods and systems for identifying an image as a representative image for an article
    Patent number: 7580568
    Abstract: Methods and systems that identify a representative image for an article are described. In one aspect of the invention, an article is received, an image data signal is determined for each image associated with the article, and a representative image based at least in part on an image data signal is determined.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: August 25, 2009
    Assignee: Google Inc.
    Inventors: Niniane Wang, Stephen R. Lawrence, Christopher M. Prince
  • Method for determining a cardiac function
    Publication number: 20090187110
    Abstract: A method for determining a cardiac function, comprising (i) determining base anatomical characteristics associated with the subject, (ii) determining pulse delay to a first body site (PD01) and a second body site (PD02) as a function of the anatomical characteristics, wherein the distance via the arterial tree from the aortic valve to the first body site (PD01) is different than the arterial tree distance from the aortic valve to the second body site (PD02), (iii) determining pulse wave velocity between the first body site and the second body site (PWV12), (iv) determining pulse wave velocity between the aortic valve and the first body site (PWV01) as a function of PWV12, and the anatomical characteristics; and (v) determining the pre-ejection period (PEP) as a function of PD01 and PWV01.
    Type: Application
    Filed: January 23, 2008
    Publication date: July 23, 2009
    Inventors: Gregory I. Voss, James M. Perry, Rankin A. Clinton, III, Bernhard B. Sterling, Andrew R. Lawrence
  • Sintered wire cathode
    Patent number: 7545089
    Abstract: A porous cathode structure is fabricated from a plurality of wires which are placed in proximity to each other in elevated temperature and pressure for a sintering time. The sintering process produces the porous cathode structure which may be divided into a plurality of individual porous cathodes, one of which may be placed into a dispenser cathode support which includes a cavity for containing a work function reduction material such as BaO, CaO, and Al2O3. The work function reduction material migrates through the pores of the porous cathode from a work replenishment surface adjacent to the cavity of the dispenser cathode support to an emitting cathode surface, thereby providing a dispenser cathode which has a uniform work function and therefore a uniform electron emission.
    Type: Grant
    Filed: March 21, 2005
    Date of Patent: June 9, 2009
    Assignee: Calabazas Creek Research, Inc.
    Inventors: Louis R. Falce, R. Lawrence Ives
  • Methods and systems for personalized network searching
    Patent number: 7523096
    Abstract: Systems and methods for personalized network searching are described. A search engine implements a method comprising receiving a search query, determining a personalized result by searching a personalized search object using the search query, determining a general result by searching a general search object using the search query, and providing a search result for the search query based at least in part on the personalized result and the general result. The search engine may utilize ratings or annotations associated with the previously identified uniform resource locator to locate and sort results.
    Type: Grant
    Filed: December 3, 2003
    Date of Patent: April 21, 2009
    Assignee: Google Inc.
    Inventors: Gregory Joseph Badros, Stephen R. Lawrence
  • Two stage hydrocracking process using beta zeolite for production of LPG and distillate hydrocarbons
    Patent number: 7462276
    Abstract: Increased yields of LPG and middle distillate products are obtained in a two stage hydrocracking process by the use of a catalyst containing a beta zeolite. In embodiments, the beta zeolite has not been hydrothermally treated or has been hydrothermally treated at a relatively low temperature. In another embodiment, the catalyst contains a relatively low amount of beta zeolite.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: December 9, 2008
    Assignee: UOP LLC
    Inventors: Li Wang, Hemant B. Gala, Christopher J. Anderle, Roger R. Lawrence
  • Systems and methods for unification of search results
    Patent number: 7437353
    Abstract: Systems and methods for the unification of search results are described. In one described system, a program, such as a search engine, executing on a client device receives a search query. The search engine executes the search on a local index and receives a first result set, which is relevant to the query entered by the user. The search query is also executed against a global index. The search engine receives a second result set from the global index. Once the search engine has received both result sets, the search engine combines the result sets to create a combined result set. The search engine may cause the combined result set to be displayed or otherwise output to a user.
    Type: Grant
    Filed: December 31, 2003
    Date of Patent: October 14, 2008
    Assignee: Google Inc.
    Inventors: David Marmaros, Nikhil Bhatta, Stephen R. Lawrence
  • Personalized Network Searching
    Publication number: 20080215553
    Abstract: Personalized network searching, in which a search query is received from a user, and a request is received to personalize a search result. Responsive to the search query and the request to personalize the search result, a personalized search result is generated by searching a personalized search object. Responsive to the search query, a general search result is generated by searching the general search object. The personalized search result and the general search result are provided to a client device, an advertisement is selected based at least in part upon the personalized search object, and the advertisement, the personalized search result, and the general search result are displayed.
    Type: Application
    Filed: April 8, 2008
    Publication date: September 4, 2008
    Applicant: Google Inc.
    Inventors: Gregory Joseph Badros, Stephen R. Lawrence
  • Methods and systems for capturing information
    Patent number: 7412708
    Abstract: Systems and methods for capturing information are described. In one embodiment, an event having an associated article is identified, article data associated with the article is identified, and a capture score for the event is determined based at least in part on article data. Article data can comprise, for example, one or a combination of a location of the article, a file-type of the article, and access data for the article. Event data associated with the event is compiled responsive at least in part to a comparison of the capture score and a threshold value.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: August 12, 2008
    Assignee: Google Inc.
    Inventors: Omar Habib Khan, Stephen R. Lawrence
  • Inhibition of Shp2/PTPN11 Protein Tyrosine Phosphatase by NSC-87877, NSC-117199 and Their Analogs
    Publication number: 20080176309
    Abstract: Compounds and associated methods for inhibiting a protein tyrosine phosphatase. By a combination of experimental and virtual screenings of the NCI Diversity Set chemical library, NSC-87877 and NSC-117199 have been identified as Shp2 PTP inhibitors. Significantly, NSC-87877 is active in cell-based assays and has no detectable off-target effects in the EGF-stimulated Erk1/2 activation pathway. Additionally, a number of analogs of NSC-117199 have been produced. These analogs exhibit enhanced protein tyrosine phosphatase inhibition and are found to be potent and/or selective inhibitors of Shp1 and/or Shp2 protein tyrosine phosphatases.
    Type: Application
    Filed: April 9, 2007
    Publication date: July 24, 2008
    Applicants: UNIVERSITY OF SOUTH FLORIDA, H. Lee Moffitt Cancer Center and Research Institute, Inc.
    Inventors: Jie Wu, Nicholas J. Lawrence, Said M. Sebti, Harshani R. Lawrence
  • Systems and methods for generating multiple implicit search queries
    Publication number: 20080077558
    Abstract: Systems and methods for generating multiple implicit search queries are described. In one described system, a query system receives a user context attribute and generates a plurality of implicit search queries based at least in part on the user context attribute. The query system then receives result sets associated with each of the plurality of implicit search queries and combines the results for display to a user.
    Type: Application
    Filed: March 31, 2004
    Publication date: March 27, 2008
    Inventors: Stephen R. Lawrence, Niniane Wang
  • Methods and systems for processing contact information
    Patent number: 7333976
    Abstract: Systems and methods for processing contact information are described. In one embodiment, an entity name is identified from an event associated with an article, wherein the entity name is associated with an entity and the event is associated with a user, contact information associated with the entity name is identified, the entity name and at least some of the contact information is indexed, and the entity name and at least some of the contact information is stored.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: February 19, 2008
    Assignee: Google Inc.
    Inventors: David Benjamin Auerbach, Stephen R. Lawrence
  • Sintered wire annode
    Patent number: 7313226
    Abstract: A plurality of high atomic number wires are sintered together to form a porous rod that is parted into porous disks which will be used as x-ray targets. A thermally conductive material is introduced into the pores of the rod, and when a stream of electrons impinges on the sintered wire target and generates x-rays, the heat generated by the impinging x-rays is removed by the thermally conductive material interspersed in the pores of the wires.
    Type: Grant
    Filed: September 14, 2005
    Date of Patent: December 25, 2007
    Assignee: Calabazas Creek Research, Inc.
    Inventors: Louis R. Falce, R. Lawrence Ives
  • Methods and systems for generating textual information
    Patent number: 7310633
    Abstract: Methods and systems for generating textual information are disclosed. In one exemplary embodiment, a method of generating textual information is disclosed that comprises identifying a plurality of candidate summaries related to textual information based at least in part on a document, determining first and second attribute values based at least in part on the candidate summaries, and determining an optimal candidate summary based at least in part on the first and second attribute values.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: December 18, 2007
    Assignee: Google Inc.
    Inventors: Niniane Wang, Stephen R. Lawrence