Abstract: The present disclosure generally relates to systems and methods for generating data representative of multi-product insurance discounts and related user interface displays. The systems and methods may include receiving personal data from an insurance customer and insurance product data. The systems and methods may further include generating data representative of multi-product insurance discounts based on personal data from an insurance customer and insurance product data. The systems and methods may further include generating displays of the multi-product discounts based on data representative of multi-product insurance discounts.

Abstract: The present specification discloses a neuromodulation system comprising a transcranially mounted neuromodulation device and a stimulation control computing environment. The disclosed neuromodulation device comprising at least one ultrasound transducer and at least one EEG electrode and the disclosed stimulation control computing environment comprises a stimulation control unit and offline computing device, the disclosed stimulation control unit including associated systems and methods for controlling the neuromodulation device functionality using acoustic simulations performed on brain image data as well as methods and uses of such neuromodulation systems in modulating brain activity using focused ultrasound stimulation of the thalamus and thalamic sub regions during certain phases of slow wave brain oscillations in order to treat various neural-based disorders or conditions including sleep disorders.

Abstract: In some embodiments, optical fiber monitoring may be facilitated. In some embodiments, monitoring of an optical fiber may be performed via a detection system to detect changes in the optical fiber that are indicative of one or more events. During the monitoring, a monitor signal may be transmitted along the optical fiber via a light source, where the monitor signal is received by the detection system as light from the optical fiber. While the detection system continues to receive light from the optical fiber in connection with the transmitting of the monitor signal, a test disturbance event may be caused to occur at a predetermined location along the optical fiber via a device at the predetermined location. In response to a failure of the detection system to detect test-related changes in the optical fiber caused by the test disturbance event, a notification indicating an issue may be generated.

Abstract: The invention relates to a dengue virus tetravalent vaccine containing a common 30 nucleotide deletion (?30) in the 3?-untranslated region of the genome of dengue virus serotypes 1, 2, 3, and 4, or antigenic chimeric dengue viruses of serotypes 1, 2, 3, and 4.

Abstract: The invention is related to a dengue virus or chimeric dengue virus that contains a mutation in the 3? untranslated region (3?-UTR) comprising a ?30 mutation that removes the TL-2 homologous structure in each of the dengue virus serotypes 1, 2, 3, and 4, and nucleotides additional to the ?30 mutation deleted from the 3?-UTR that removes sequence in the 5? direction as far as the 5? boundary of the TL-3 homologous structure in each of the dengue serotypes 1, 2, 3, and 4, or a replacement of the 3?-UTR of a dengue virus of a first serotype with the 3?-UTR of a dengue virus of a second serotype, optionally containing the ?30 mutation and nucleotides additional to the ?30 mutation deleted from the 3?-UTR; and immunogenic compositions, methods of inducing an immune response, and methods of producing a dengue virus or chimeric dengue virus.

Abstract: The present specification discloses a neuromodulation system comprising a transcranially mounted neuromodulation device and a stimulation control computing environment. The disclosed neuromodulation device comprising at least one ultrasound transducer and at least one EEG electrode and the disclosed stimulation control computing environment comprises a stimulation control unit and offline computing device, the disclosed stimulation control unit including associated systems and methods for controlling the neuromodulation device functionality using acoustic simulations performed on brain image data as well as methods and uses of such neuromodulation systems in modulating brain activity using focused ultrasound stimulation of the thalamus and thalamic sub regions during certain phases of slow wave brain oscillations in order to treat various neural-based disorders or conditions including sleep disorders.

Abstract: In an optical fiber monitoring system which detects physical disturbance or other parameters such as temperature or strain of a fiber where a monitor signal is transmitted along the optical fiber and analyzed to detect changes which are indicative of an event, a method is provided for periodically checking proper operation of the optical fiber monitoring system. A fiber disturbance actuator periodically causes a pattern of disturbances of a portion of the fiber at a predetermined location thereon where the disturbance is characteristic of the event to be monitored. The monitor signal is analyzed to detect the pattern of changes and in the event that expected changes are not detected, a warning is issued that the intrusion detection system is not properly operating.

Abstract: This disclosure provides a thermal diode including a first plate having a first surface defining a wick structure. The thermal diode can include a second plate having a smooth surface facing the wick structure, the smooth surface and the wick structure defining a chamber for accommodating a phase-change liquid. The thermal diode also can include a separator positioned between the first plate and the second plate to separate the wick structure from the smooth surface by a gap that is less than a capillary length of the phase-change liquid.

Abstract: A method is provided for analyzing a monitoring signal from a sensing system to determine an alarm condition, where the monitoring signal is provided as a stream of digital values which are analyzed using a frequency-based or time-based algorithm to generate a plot of elements, applying a delta to each element of the plot of elements to adjust sensitivity thereof to provide a threshold and comparing a plurality of the elements of the stream with the threshold and triggering the alarm condition in the event that the threshold is exceeded; where the algorithm is changed in different time periods in response to ambient conditions of the environment determined for those time periods.

Abstract: The present invention is a DNA expression vector comprising: a toxP: a mutant toxO that blocks Fe-mediated regulation of gene expression; and a DNA sequence encoding a protein, wherein the toxP and the mutant toxO regulate expression of the DNA segment encoding the protein. It is preferred that DNA expression vectors of the present invention include DNA sequences encoding a signal peptide so that a protein expressed is attached to the signal peptide prior to processing. Novel proteins are produced off of the DNA expression vector of the present invention.

Abstract: Methods and systems for determining a radar compatible coating are provided. In one example, the method includes obtaining a reflectance measurement of a target coating to characterize a color of the target coating. One or more candidate formulas are generated to determine color matching to the color of the target coating. A corresponding color and a corresponding radar property for each of the one or more candidate formulations is predicted. A radar compatible coating composition that is the same or substantially similar in appearance to the target coating is generated. Generating the radar compatible coating composition is based at least in part on the corresponding color and the corresponding radar property for one of the one or more candidate formulations.

Abstract: A head-wearable device is configured to hold at least one ultrasound transducer such that it is properly positioned for brain stimulation. Such a head-wearable device can help to ensure that the transducer makes sufficient contact with the user's head to allow for efficient ultrasound coupling. Each device may also ensure that the ultrasound transducer maintains the same orientation and position relative to the head across successive donning and doffing of the device.

Abstract: In an optical fiber monitoring system which detects physical disturbance or other parameters such as temperature or strain of a fiber where a monitor signal is transmitted along the optical fiber and analyzed to detect changes which are indicative of an event, a method is provided for periodically checking proper operation of the optical fiber monitoring system. :A fiber disturbance actuator periodically causes a pattern of disturbances of a portion of the fiber at a predetermined location thereon where the disturbance is characteristic of the event to be monitored. The monitor signal is analyzed to detect the pattern of changes and in the event that expected changes are not detected, a warning is issued that the intrusion detection system is not properly operating.

Abstract: A system and method for detecting multiple incidents in a set of flow meter units attached to a set of water consuming units. A plurality of uniquely identified flow meter units are operatively connected to a central control unit. The control unit is programmable to send alerts based on leaking incident status of particular flow meter units so that a responder may receive the alert and timely address the alert. The central control receives and stores data from the multiple flow meter units, including volumetric flow, time, and status and location of each alert. A method of detecting leaking in a building having multiple separate units, each unit having a unit water supply, includes placing a specially configured controller having a flow meter and automatic shut-off valve in each unit of the building. Leak sensors are positioned in water-leak risk areas wherein the controller communicates with both the flow meter and the sensors. A communication is established in between the controller and the sensors.

Abstract: A computer-implemented method for marking an object on an aligner. The aligner surface is modeled. The method includes calculating a normal for each tile in a tessellated surface and disqualifying a tile from being selected. For tiles not disqualified, a patch is identified that produces a markable area. The method includes selecting an object to be marked, calculating a location of the object in the markable area, and providing the location of the object to a marking device. Disqualifying includes comparing an angle between a normal and an orientation of the beam to an origin of the calculated normal on each tile. Disqualifying includes disqualifying the at least one tile when the angle is outside of a range of ?90° to +90°. Identifying the patch includes separating the patch into at least two smaller patches, and one of the two smaller patches of tiles is the markable area.

Abstract: In an optical fiber monitoring system which detects physical disturbance or other parameters such as temperature or strain of a fiber where a monitor signal is transmitted along the optical fiber and analyzed to detect changes which are indicative of an event, a method is provided for periodically checking proper operation of the optical fiber monitoring system. A fiber disturbance actuator periodically causes a pattern of disturbances of a portion of the fiber at a predetermined location thereon where the disturbance is characteristic of the event to be monitored. The monitor signal is analyzed to detect the pattern of changes and in the event that expected changes are not detected, a warning is issued that the intrusion detection system is not properly operating.

Abstract: Embodiments of the present disclosure generally relate to apparatus for and methods of detecting light utilizing the spin Seebeck effect (SSE). In an embodiment, a method for detecting broadband light is provided. The method includes generating a SSE in a device by illuminating the device with light, the device comprising a bilayer structure disposed over a substrate, the bilayer structure comprising a non-magnetic metal layer and a magnetic insulator layer. The method further includes measuring the SSE based on a field modulation method, determining, based on the measuring, an optically-created thermal gradient of the device, and detecting a wavelength range of the light. Apparatus for detecting broadband light are also described.

Abstract: Methods and systems for determining a radar compatible coating are provided. In one example, the method includes obtaining a reflectance measurement of a target coating to characterize a color of the target coating. One or more candidate formulas are generated to determine color matching to the color of the target coating. A corresponding color and a corresponding radar property for each of the one or more candidate formulations is predicted. A radar compatible coating composition that is the same or substantially similar in appearance to the target coating is generated. Generating the radar compatible coating composition is based at least in part on the corresponding color and the corresponding radar property for one of the one or more candidate formulations.

Abstract: In an optical fiber monitoring system which detects physical disturbance or other parameters such as temperature or strain of a fiber where a monitor signal is transmitted along the optical fiber and analyzed to detect changes which are indicative of an event, a method is provided for periodically checking proper operation of the optical fiber monitoring system. A fiber disturbance actuator periodically causes a pattern of disturbances of a portion of the fiber at a predetermined location thereon where the disturbance is characteristic of the event to be monitored. The monitor signal is analyzed to detect the pattern of changes and in the event that expected changes are not detected, a warning is issued that the intrusion detection system is not properly operating.

Abstract: In an optical fiber monitoring system which detects physical disturbance or other parameters such as temperature or strain of a fiber where a monitor signal is transmitted along the optical fiber and analyzed to detect changes which are indicative of an event, a method is provided for periodically checking proper operation of the optical fiber monitoring system. A fiber disturbance actuator periodically causes a pattern of disturbances of a portion of the fiber at a predetermined location thereon where the disturbance is characteristic of the event to be monitored. The monitor signal is analyzed to detect the pattern of changes and in the event that expected changes are not detected, a warning is issued that the intrusion detection system is not properly operating.