Abstract: As disclosed herein, optimal native genomic loci from maize plants have been identified that represent best sites for targeted insertion of exogenous sequences.

Abstract: A system and method using magnetic sensing to non-intrusively and non-destructively characterize ferromagnetic material within infrastructure. The system includes sensors for measuring magnetic field gradients from a standoff distance adjacent to ferromagnetic material. The method includes using the system to measure magnetic fields, determining magnetic field gradients measured by a sensor array, and comparing measured and modeled or historical magnetic field gradients at the same or similar positions to identify differences caused by a phenomenon in the ferromagnetic material, and, in a particular embodiment, to recognize defects and developing defects.

Abstract: A method of gene editing or gene stacking within a FAD2 loci by cleaving, in a site directed manner, a location in a FAD2 gene in a cell, to generate a break in the FAD2 gene and then ligating into the break a nucleic acid molecule associated with one or more traits of interest is disclosed.

Abstract: A switch monitoring system is provides information on sensor readings and contact closures over a one-wire network or a loop.

Abstract: A method of gene editing or gene stacking within a FAD3 loci by cleaving, in a site directed manner, a location in a FAD3 gene in a cell, to generate a break in the FAD3 gene and then ligating into the break a nucleic acid molecule associated with one or more traits of interest is disclosed.

Abstract: As disclosed herein, optimal native genomic loci of soybean plants have been identified that represent best sites for targeted insertion of exogenous sequences.

Abstract: A system and accompanying methods provide for the creation and navigation of interactive, three-dimensional media presentations. A three-dimensional presentation is received, and includes a three-dimensional canvas having integrated therein a plurality of two-dimensional content elements from a first content source and a plurality of three-dimensional content elements from a second content source. The two-dimensional content elements and the three-dimensional content elements relate to a common topic. The three-dimensional presentation is displayed to a user on a user device by moving a virtual camera about the three-dimensional canvas over a plurality of defined motion paths. While displaying the three-dimensional presentation to the user, user navigation instructions with respect to a first one of the integrated content elements are received.

Abstract: A method of gene editing or gene stacking within a FAD2 loci by cleaving, in a site directed manner, a location in a FAD2 gene in a cell, to generate a break in the FAD2 gene and then ligating into the break a nucleic acid molecule associated with one or more traits of interest is disclosed.

Abstract: A method of gene editing or gene stacking within a FAD3 loci by cleaving, in a site directed manner, a location in a FAD3 gene in a cell, to generate a break in the FAD3 gene and then ligating into the break a nucleic acid molecule associated with one or more traits of interest is disclosed.

Abstract: As disclosed herein, optimal native genomic loci of soybean plants have been identified that represent best sites for targeted insertion of exogenous sequences.

Abstract: Systems, methods, and devices are provided that combine an advance vehicle configuration, such as an advanced aircraft configuration, with the infusion of electric propulsion, thereby enabling a four times increase in range and endurance while maintaining a full vertical takeoff and landing (“VTOL”) and hover capability for the vehicle. Embodiments may provide vehicles with both VTOL and cruise efficient capabilities without the use of ground infrastructure. An embodiment vehicle may comprise a wing configured to tilt through a range of motion, a first series of electric motors coupled to the wing and each configured to drive an associated wing propeller, a tail configured to tilt through the range of motion, a second series of electric motors coupled to the tail and each configured to drive an associated tail propeller, and an electric propulsion system connected to the first series of electric motors and the second series of electric motors.

Abstract: A single input engine controller and system are provided for translating a single input indicative of the amount of fuel to be supplied to an engine from a fuel control interface into separate signals for controlling the amount of fuel supplied to the engine and the RPM of a propeller powered by that engine. The single input controller translating the single input into the separate signal for the RPM of the propeller according to a fuel efficiency relationship between the fuel amount and the propeller RPM.

Abstract: A system and method using magnetic sensing to non-intrusively and non-destructively characterize ferromagnetic material within infrastructure. The system includes sensors for measuring magnetic field gradients from a standoff distance adjacent to ferromagnetic material. The method includes using the system to measure magnetic fields, determining magnetic field gradients measured by a sensor array, and comparing measured and modeled or historical magnetic field gradients at the same or similar positions to identify differences caused by a phenomenon in the ferromagnetic material, and, in a particular embodiment, to recognize defects and developing defects.

Abstract: The present disclosure provides methods for detecting and identifying plant events that contain precision targeted genomic loci, and plants and plant cells comprising such targeted genomic loci. The method can be deployed as a high throughput process utilized for screening the intactness or disruption of a targeted genomic loci and optionally for detecting a donor DNA polynucleotide insertion at the targeted genomic loci. The methods are readily applicable for the identification of plant events produced via a targeting method which results from the use of a site specific nuclease.

Abstract: The present invention is directed to a novel poly(diol citrates)-based nanocomposite materials created using completely biodegradable and biocompatible polymers that may be used in tissue engineering. More specifically, the specification describes methods and compositions for making and using nanocomposites comprised of citric acid copolymers and polymers including but not limited to poly(L-lactic acid) (PLLA) and poly(lactic-co-glycolic acid) (PLGA).

Abstract: Provided are methods for introducing a sequence-specific nuclease into a plant cell comprising a cell wall. Methods are provided for genetically or otherwise modifying plants and for treating or preventing disease in plant cells comprising a cell wall.

Abstract: An oxygen number density or concentration sensor including a sampling luminescent oxygen probe located in a fluid environment, and a gas impermeable enclosure located in the fluid environment and a reference luminescent oxygen probe located within the gas impermeable enclosure, wherein the sampling and reference luminescent oxygen probes are formed by an ideal PSP. A predetermined fixed oxygen number density or concentration is provided within a medium contained in the gas impermeable enclosure. A detector receives signals corresponding to luminescent emissions of the sampling and reference probes. A processor determines a number density or concentration of oxygen in the fluid environment from a signal generated at the sampling probe with reference to an oxygen number density or concentration dependent signal generated at the reference probe.

Abstract: In one aspect, the invention relates to compounds having anticancer activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with uncontrolled cellular proliferation using the compounds and compositions. This abstract is intended to be used as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: A clean-in-place system for piping systems uses a pig train having a dry ice and glycol section. The pig train is moved through the piping system as part of a cleaning sequence. The system and method of the disclosure provide an alternative, effective clean-in-place system that significantly reduces water, chemical and energy usage as well as significantly reducing the related environmental impact.