Abstract: An electronic device for determining a level of toner volume in a replacement toner cartridge used in a printing device comprises a communication element, a memory element, and a processing element. The communication element transmits a request to the printing device to provide data regarding the replacement toner cartridge and receives the data. The data includes a current level of toner volume and a current printed page count. The memory element stores the data received from the printing device. The processing element is in communication with the communication element and the memory element. The processing element is configured to determine one of a plurality of sequential phases of a usage cycle of the replacement toner cartridge corresponding to a value of the current level of toner volume and determine a corrected level of toner volume using one of a plurality of equations selected according to the phase.

Abstract: A vehicle wiper assembly includes a wiper blade having a length, and an active material disposed along the length of the wiper blade and coupled thereto. The active material includes a shape memory alloy material with a crystallographic phase that is changeable between austenite and martensite, and is elastically deformable and operatively applies a spring force against a portion of the wiper blade when the crystallographic phase is martensite.

Abstract: In one aspect, the invention relates to novel, broad-spectrum anti-viral, pyrimidinone compounds, methods of use, compositions and kits useful in treating and/or preventing influenza. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: An electronic device for determining a level of toner volume in a replacement toner cartridge used in a printing device comprises a communication element, a memory element, and a processing element. The communication element transmits a request to the printing device to provide data regarding the replacement toner cartridge and receives the data. The data includes a current level of toner volume and a current printed page count. The memory element stores the data received from the printing device. The processing element is in communication with the communication element and the memory element. The processing element is configured to determine one of a plurality of sequential phases of a usage cycle of the replacement toner cartridge corresponding to a value of the current level of toner volume and determine a corrected level of toner volume using one of a plurality of equations selected according to the phase.

Abstract: A secondary barrier for use in conjunction with an isolation device in a portion of a non-vertical wellbore comprises: a swellable material, wherein the swellable material: (A) has dimensions such that, prior to swelling, the secondary barrier is capable of being placed into the portion of the non-vertical wellbore, and (B) fills a void within the portion of the non-vertical wellbore, wherein the swellable material fills the void after the swelling of at least a portion of the swellable material has occurred, wherein the secondary barrier is positioned adjacent to the isolation device in the portion of the non-vertical wellbore. A method of creating a secondary barrier comprises: introducing the secondary barrier into the portion of the non-vertical wellbore; and contacting or allowing the swellable material to come in contact with the swelling fluid or the increase in temperature.

Abstract: In one aspect, the invention relates to compounds having anticancer activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with uncontrolled cellular proliferation using the compounds and compositions. This abstract is intended to be used as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: A switch monitoring system is provides information on sensor readings and contact closures over a one-wire network or a loop

Abstract: Provided are methods for introducing a sequence-specific nuclease into a plant cell comprising a cell wall. Methods are provided for genetically or otherwise modifying plants and for treating or preventing disease in plant cells comprising a cell wall.

Abstract: A clean-in-place system for piping systems uses a pig train having a dry ice and glycol section. The pig train is moved through the piping system as part of a cleaning sequence. The system and method of the disclosure provide an alternative, effective clean-in-place system that significantly reduces water, chemical and energy usage as well as significantly reducing the related environmental impact.

Abstract: A drain plug assembly that has particular application for sealing a drain hole in a high voltage battery compartment on a vehicle. The plug assembly includes a plug that inserted into the drain hole. The plug assembly further includes a return spring coupled to the plug and causing the plug to be biased into the drain hole. The plug assembly also includes at least one shape memory alloy device coupled to the plug and a support structure. The SMA device receives an electrical current that causes the device to contract and move the plug out of the drain hole against the bias of the return spring.

Abstract: As disclosed herein, optimal native genomic loci from maize plants have been identified that represent best sites for targeted insertion of exogenous sequences.

Abstract: As disclosed herein, optimal native genomic loci have been identified in dicot plants, such as soybean plants, that represent best sites for targeted insertion of exogenous sequences.

Abstract: As disclosed herein, optimal native genomic loci have been identified in monocot plants, such as maize plants, that represent best sites for targeted insertion of exogenous sequences.

Abstract: As disclosed herein, optimal native genomic loci of soybean plants have been identified that represent best sites for targeted insertion of exogenous sequences.

Abstract: A method of gene editing or gene stacking within a FAD3 loci by cleaving, in a site directed manner, a location in a FAD3 gene in a cell, to generate a break in the FAD3 gene and then ligating into the break a nucleic acid molecule associated with one or more traits of interest is disclosed.

Abstract: In one aspect, the invention relates to compounds having anticancer activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with uncontrolled cellular proliferation using the compounds and compositions. This abstract is intended to be used as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: A method for producing a transgenic plant includes providing a nucleic acid molecule comprising at least two regions of nucleic acid sequence that lack sequence homology with genomic DNA of the plant cell, and at least two zinc finger nuclease recognition sites, wherein the at least two regions of nucleic acid sequence that lack sequence homology with genomic DNA of the plant cell flank the at least two zinc finger nuclease recognition sites. A plant cell or tissue having the nucleic acid molecule stably integrated into the genome of the plant cell is transformed. A plant is regenerated from the plant cell. Transgenic plants are produced by the method. Seeds are produced by the transgenic plants.

Abstract: Disclosed herein are methods and compositions for parallel or sequential transgene stacking in plants to produce plants with selected phenotypes.

Abstract: The present disclosure provides methods for detecting and identifying plant events that contain precision targeted genomic loci, and plants and plant cells comprising such targeted genomic loci. The method can be deployed as a high throughput process utilized for screening the intactness or disruption of a targeted genomic loci and optionally for detecting a donor DNA polynucleotide insertion at the targeted genomic loci. The methods are readily applicable for the identification of plant events produced via a targeting method which results from the use of a site specific nuclease.

Abstract: A method for producing a transgenic plant includes providing a nucleic acid molecule comprising at least two regions of nucleic acid sequence that lack sequence homology with genomic DNA of the plant cell, and at least two zinc finger nuclease recognition sites, wherein the at least two regions of nucleic acid sequence that lack sequence homology with genomic DNA of the plant cell flank the at least two zinc finger nuclease recognition sites. A plant cell or tissue having the nucleic acid molecule stably integrated into the genome of the plant cell is transformed. A plant is regenerated from the plant cell. Transgenic plants are produced by the method. Seeds are produced by the transgenic plants.