Abstract: A window may have a structural window layers such as an inner glass layer and an outer glass layer. The inner glass layer may be a layer of tempered glass. The outer glass layer may be a laminated glass layer. The inner and outer glass layers may be separated by an air gap. One or more reflection suppression layers such as antireflection layers and/or circular polarizers may be incorporated into the window to suppress reflections of light from within the interior region off of the window back towards the interior region. The antireflection layers may be formed on one or both surfaces of the inner glass and one or both surfaces of the outer glass. An electrically adjustable layer such as a guest-host liquid crystal light modulator layer or other electrically adjustable optical component layer may be interposed between the outer glass layer and the air gap.

Abstract: An improved method of culturing cells for cell therapy applications that includes growing desired cells in the presence of antigen-presenting cells and/or feeder cells and with medium volume to surface area ratio of up to 1 ml/cm2 if the growth surface is not comprised of gas permeable material and up to 2 ml/cm2 if the growth surface is comprised of gas permeable material. The desired cells are at a surface density of less than 0.5×106 cells/cm2 at the onset of a production cycle, and the surface density of the desired cells plus the surface density of the antigen presenting cells and/or feeder cells are at least about 1.25×105 cells/cm2.

Abstract: In general, the present invention is directed to a building panel, such as a gypsum board, comprising a core having a first side and a second side opposing the first side and at least one facing material having a coating comprising at least one fungicide, at least one polymeric binder, and at least one pigment. The panel satisfies at least one of the following: the board exhibits a rating of 2 or less when tested in accordance to ASTM G21-15 or the board exhibits a rating of at least 8 when tested in accordance to ASTM D3273-16. The panel may also exhibit at least a Level 3 finish.

Abstract: A sheet of polymeric material is made using an extruding process and articles are formed from the sheet of polymeric material. The sheet of polymeric material and the articles comprise one or more polypropylene resins. In some embodiments, the sheet of polymeric material and the articles formed form the sheet of polymeric material are transparent.

Abstract: A container includes a cup and a lid. The lid is adapted to mate with a brim included in the cup to close a top aperture opening into an interior liquid-storage region formed in the cup.

Abstract: Polyurethanes are made in a one-shot process from one or more polyols having a hydroxyl equivalent weight of at least 350, wherein at least 50% of the weight of iii) is a hydroxyl-containing polymer of propylene oxide, the hydroxyl-containing polymer of propylene oxide having a hydroxyl equivalent weight of at least 350, an average of 1.8 to 3 hydroxyl groups per molecule of which hydroxyl groups 40 to 70% are primary hydroxyl groups, an oxyethylene content of no greater than 10% by weight based on the weight of the polymer and a polydispersity of 1.175 or less. The polyurethanes exhibit excellent mechanical properties, are highly hygroscopic and cured rapidly.

Abstract: A blockchain enabled electronic futures trading system and method provided which allows for optional computerized delivery of cryptocurrency. A trade determination system allows a buyer and seller computer system to trade a future on a cryptocurrency such as bitcoin. Additionally, the trade determination system communicates with a central clearing computer system that allows the seller to provide, using the block chain, an amount of bitcoin equal to or greater than the underlying future by transferring the bitcoin from a seller bitcoin wallet associated with the seller computer system to a central clearing bitcoin wallet associated with the central clearing computer system. Upon the expiration date of the future, the seller may optionally select to provide to the buyer the bitcoin that was previously transferred to the central clearing bitcoin wallet instead of fiat currency.

Abstract: An exercise system includes a resistance unit for the performance of a wide variety of exercises including those previously performed using free weights, exercise machines, rowing machines, and/or ski machines. The resistance unit is configured with power rewind such that the resistance for both pull-out and rewind is determined by the resistance developed by a clutch assembly having clutch-plates slipping against friction pads in the clutch-assembly, resulting in the resistance for pulling out and rewinding being virtually the same.

Abstract: An automated plate shaping and verification system allows for the accurate and efficient transformation of a metal plate from a starting shape to a target shape. Using a method for path planning, the system can select heating patterns based on modeling the expected deformation of a particular material type and thickness and identifying candidate heating paths that will sufficiently cause the plate to transform towards the target shape.

Abstract: Light-control panels including layered optical components are described in this application. An example of a light-control panel includes a first glazing layer, a second glazing layer, a third glazing layer, and a fourth glazing layer, a first switchable component extending between the first glazing layer and the second glazing layer, a thermal coating extending between the first glazing layer and the first switchable component, and a second switchable component extending between the third glazing layer and the fourth glazing layer. The second glazing layer and the third glazing layer have an air gap therebetween, such that the air gap forms a space between the second glazing layer and the third glazing layer.

Abstract: Disclosed is a low-cost, in-line process for treating a fibrous web with a lotion. The process generally involves passing a web through a nip formed by a pair of opposed surfaces, where one of the surfaces has been treated with a lotion having a penetration hardness greater than 5.0 mm. As the web passes through the nip, the lotion is transferred from one of the opposed surfaces to the surface of the web. In certain instances, the web may have a textured surface and only a portion of the web's textured surface is treated with a lotion.

Abstract: Relationship management systems in accordance with embodiments of the invention are configured to provide systematic ways for a user to measure, and manage relationships in the user's social network. One embodiment of the invention includes a relationship management server system, and a database. In addition, the relationship management server system is configured to store a user account associated with a user in the database, store information concerning contacts associated with the user in the database, store event information associated with the user and at least one of the stored contacts in the database, store at least one objective in the database, score at least one relationship between the user and a contact based upon stored event information associated with the user and the contact to create a scored relationship graph, and generate a recommendation concerning an action based upon the stored objective and the scored relationship graph.

Abstract: A system for implanting a flow modifying device in a heart comprises a flow modifying device comprising a tubular body comprising first and second openings located at first and second ends of the tubular body and a neck positioned between the first opening and the second opening, and a guide catheter comprising a flexible elongate shaft comprising a proximal portion comprising a fitting for receiving an insertion instrument and distal portion comprising an enlarged distal tip to prevent the flexible elongate shaft from passing through the flow modifying device. A guide catheter for cannulating a coronary sinus from a superior vena cava comprises a pre-formed distal portion comprising a proximal straight zone, a proximal curved zone extending along a first curved path, a distal straight zone extending along a straight path and a distal curved zone extending along a second curved path. The guide catheter can have different stiffnesses.

Abstract: An improved method of culturing cells for cell therapy applications that includes growing desired cells in the presence of antigen-presenting cells and/or feeder cells and with medium volume to surface area ratio of up to 1 ml/cm2 if the growth surface is not comprised of gas permeable material and up to 2 ml/cm2 if the growth surface is comprised of gas permeable material. The desired cells are at a surface density of less than 0.5×106 cells/cm2 at the onset of a production cycle, and the surface density of the desired cells plus the surface density of the antigen presenting cells and/or feeder cells are at least about 1.25×105 cells/cm2.

Abstract: A method of producing a polyether alcohol that includes feeding an initiator into a reactor, feeding one or more monomers into the reactor, feeding a polymerization catalyst into the reactor, the polymerization catalyst being a Lewis acid catalyst having a general formula M(R1)1(R2)1(R3)1(R4)0 or 1, separate from feeding the initiator into the reactor, feeding a hydrogen bond acceptor additive into the reactor, the hydrogen bond acceptor additive being a C2 to C20 organic molecule having at least two hydroxyl groups, of which two hydroxyl groups are situated in 1,2-, 1,3-, or 1,4-positions on the organic molecule, and allowing the initiator to react with the one or more monomers in the presence of the polymerization catalyst and the hydrogen bond acceptor additive to form a polyether alcohol having a number average molecular weight greater than a number average molecular weight of the initiator.

Abstract: The invention provides formulations for oral delivery of a therapeutic agent wherein the formulation comprises a kappa opioid receptor agonist, an oligosaccharide stabilizing agent and an optional absorption enhancer. The kappa opioid receptor agonist may be coated with, embedded in or mixed with an oligosaccharide, such as trehalose. Also provided are capsules containing the oral formulations of the kappa opioid receptor agonists, the oligosaccharide and the absorption enhancer of the invention. The invention further provides methods of manufacture of the formulations and methods of their use for the prophylaxis, inhibition and treatment of variety of kappa opioid receptor-associated diseases and conditions such as pain, pruritus and inflammation. The methods of use include administering to the mammal the formulation of the kappa opioid receptor agonist, oligosaccharide and optional absorption enhancers.

Abstract: A method of producing an alcohol ethoxylate surfactant or lubricant, the method including reacting a low molecular weight initiator with ethylene oxide in the presence of a polymerization catalyst, the low molecular weight initiator having a nominal hydroxyl functionality at least 1, and the polymerization catalyst being a Lewis acid catalyst having the general formula M(R1)I(R2)I(R3)I(R4)0 or 1, whereas M is boron, aluminum, indium, bismuth or erbium, R1, R2, R3, and R4 are each independent, R1 includes a first fluoroalkyl-substituted phenyl group, R2 includes a second fluoroalkyl-substituted phenyl group or a first fluoro/chloro-substituted phenyl group, R3 includes a third fluoroalkyl-substituted phenyl group or a second fluoro/chloro-substituted phenyl group, and optional R4 includes a functional group or functional polymer group, R1 being different from at least one of R2 and R3.

Abstract: A sheet of polymeric material is made using an extruding process and articles are formed from the sheet of polymeric material. The sheet of polymeric material and the articles comprise one or more polypropylene resins. In some embodiments, the sheet of polymeric material and the articles formed form the sheet of polymeric material are transparent.

Abstract: Improved cell culture devices and related methods that overcome the limitations of prior devices and methods, by creating devices that can integrate a variety of novel attributes. These various attributes include the use of gas permeable material and medium volumes that exceed conventional devices as well as compartments that can facilitate the long term study of high density cultures with reduced disruption of the culture environment, the ability to study the migration of items of interest including substances such as chemokine, track the movement of cells, and monitor cell to cell interactions.

Abstract: An in vitro expansion process for rapid expansion of antigen specific T cells, such as allogeneic antigen specific T cells comprising the steps culturing in a gas permeable vessel a population of PBMCs (such as allogeneic PBMCs) in the presence of antigen, for example a peptide or peptide mix relevant to a target antigen(s), in the presence of an exogenous cytokine characterized in that the expansion to provide the desired population of T cells is 14 days or less, for example 9, 10, 11 or 12 days, such as 10 days. The disclosure also extends to T cell populations generated by and obtained from the method and the use of same in therapy.