Patents by Inventor R. Wilson

R. Wilson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11912822
    Abstract: A method of producing a polyether polyol includes reacting a low molecular weight initiator with ethylene oxide in the presence of a polymerization catalyst, and the low molecular weight initiator has a nominal hydroxyl functionality at least 2. The polymerization catalyst is a Lewis acid catalyst having the general formula M(R1)1(R2)1(R3)1(R4)0 or 1, whereas M is boron, aluminum, indium, bismuth or erbium, R1, R2, R3, and R4 are each independent, R1 includes a fluoroalkyl-substituted phenyl group, R2 incudes a fluoroalkyl-substituted phenyl group or a fluoro/chloro-substituted phenyl group, R3 includes a fluoroalkyl-substituted phenyl group or a fluoro/chloro-substituted phenyl group, and optional R4 includes a functional group or functional polymer group, R1 being different from at least one of R2 and R3.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: February 27, 2024
    Assignee: Dow Global Technologies LLC
    Inventors: Arjun Raghuraman, William H. Heath, Sukrit Mukhopadhyay, Heather A. Spinney, David R. Wilson
  • Publication number: 20240058586
    Abstract: A system for implanting a flow modifying device in a heart comprises a flow modifying device comprising a tubular body comprising first and second openings located at first and second ends of the tubular body and a neck positioned between the first opening and the second opening, and a guide catheter comprising a flexible elongate shaft comprising a proximal portion comprising a fitting for receiving an insertion instrument and distal portion comprising an enlarged distal tip to prevent the flexible elongate shaft from passing through the flow modifying device. A guide catheter for cannulating a coronary sinus from a superior vena cava comprises a pre-formed distal portion comprising a proximal straight zone, a proximal curved zone extending along a first curved path, a distal straight zone extending along a straight path and a distal curved zone extending along a second curved path. The guide catheter can have different stiffnesses.
    Type: Application
    Filed: November 9, 2022
    Publication date: February 22, 2024
    Inventors: Scott R. Wilson, Sai Ho Choy, Keith Alan Jackson, Ernest Wai Wong, Guy Patrick Vanney, Jason Lee Ladoucer, Fredericus Antonius Colen
  • Publication number: 20240061466
    Abstract: An electronic device display may have an inner layer with a pixel array for displaying images and an outer layer with an array of light modulator cells operable in transparent and light-blocking modes. Force sensor and touch sensor circuitry may be used to gather user input such as information on finger pressure or stylus input applied to a location on the display. A block of the cells may be placed into a transparent mode to form a transparent window based on information from the sensor circuitry. Images on the pixel array may be viewed through the window. In another mode of operation, images can be displayed by adjusting the cells of the light modulator layer and backlight illumination may be provided by the pixel array. A camera and a flash or other optical components may be overlapped by an adjustable shutter.
    Type: Application
    Filed: November 2, 2023
    Publication date: February 22, 2024
    Inventors: Harry K. Ng, Alvin K. Ng, Katherine E. Tong, Tyler S. Bushnell, Amin M. Younes, Benjamin S. Bustle, Christopher D. Jones, James R. Wilson
  • Patent number: 11896965
    Abstract: The invention relates to oligomerization of olefins, such as ethylene, to higher olefins, such as a mixture of 1-hexene and 1-octene, using a catalyst system that comprises a) a source of chromium b) one or more activators and c) a phosphacycle-containing ligating compound. Additionally, the invention relates to a phosphacycle-containing ligating compound and a process for making said compound.
    Type: Grant
    Filed: October 14, 2022
    Date of Patent: February 13, 2024
    Assignee: Dow Global Technologies LLC
    Inventors: Jerzy Klosin, Kara A. Milbrandt, Scott D. Boelter, David R. Wilson, Mari S. Rosen, Dean M. Welsh, Peter M. Margl, Kyoung Moo Koh, David M. Pearson, Rafael Huacuja
  • Patent number: 11891595
    Abstract: Improved cell culture devices and related methods that overcome the limitations of prior devices and methods, by creating devices that can integrate a variety of novel attributes. These various attributes include the use of gas permeable material and medium volumes that exceed conventional devices as well as compartments that can facilitate the long term study of high density cultures with reduced disruption of the culture environment, the ability to study the migration of items of interest including substances such as chemokine, track the movement of cells, and monitor cell to cell interactions.
    Type: Grant
    Filed: March 24, 2023
    Date of Patent: February 6, 2024
    Assignee: Wilson Wolf Manufacturing LLC
    Inventors: John R. Wilson, Daniel P. Welch
  • Patent number: 11891488
    Abstract: A sheet of polymeric material is made using an extruding process and articles are formed from the sheet of polymeric material. The sheet of polymeric material and the articles comprise one or more polypropylene resins. In some embodiments, the sheet of polymeric material and the articles formed form the sheet of polymeric material are transparent.
    Type: Grant
    Filed: February 5, 2020
    Date of Patent: February 6, 2024
    Assignee: Berry Global, Inc.
    Inventors: Yucheng Peng, Jonathan Eickhoff, Ryan Dewig, Jeffrey A. Mann, Debra R. Wilson
  • Patent number: 11873474
    Abstract: Novel methods and apparatus are disclosed for cell culture and cell recovery. The methods and apparatus simplify the process of cell separation from media, minimize potential damage to gas permeable devices during fluid handling, and allow closed system automated cell culture and cell recovery from gas permeable devices.
    Type: Grant
    Filed: September 16, 2021
    Date of Patent: January 16, 2024
    Assignee: Wilson Wolf Manufacturing
    Inventors: Daniel P. Welch, John R. Wilson
  • Patent number: 11872265
    Abstract: Drug delivery systems have been developed based on the formation of diketopiperazine carboxylate salts and microparticles containing the same. The systems may further comprise a bioactive agent. Related methods for making and using the biologically active agent delivery compositions are also provided. In certain embodiments, the pharmaceutically acceptable salts described can be formed by removal of solvent by methods including distillation, evaporation, spray drying or lyophilization.
    Type: Grant
    Filed: January 5, 2021
    Date of Patent: January 16, 2024
    Assignee: MANNKIND CORPORATION
    Inventors: Andrea Leone-Bay, Destardi Moye-Sherman, Bryan R. Wilson
  • Publication number: 20240002797
    Abstract: Production and use of novel therapeutic cells, called T-Vehicles, in the allogeneic Adoptive Cell Therapy setting allows a wide range of therapeutic benefits to accrue with minimal or no risk of GVHD. T-Vehicles are created from donor T cells that are altered to contain therapeutic attributes that do not include their native antigen receptors and can deliver therapeutic benefits irrelevant of their native antigen specificity. T-Vehicles can possess highly restricted native antigen specificity that renders them unable to recognize antigens present on normal cells and incapable of initiating GVHD, making them ideal transport vehicles to deliver various therapeutic attributes in vivo. In essence, production and use of T-Vehicles is a paradigm shift that opens the door to therapeutic application of T cells in ways not previously contemplated, independent of whether or not there is an HLA match between the donor and the recipient.
    Type: Application
    Filed: May 17, 2023
    Publication date: January 4, 2024
    Inventors: Juan F. Vera, Cliona M. Rooney, Ann M. Leen, John R. Wilson
  • Patent number: 11864304
    Abstract: An electronic device may include electrical components and other components mounted within an interior of a housing. The device may have a display on a front face of the device and may have a glass layer that forms part of the housing on a rear face of the device. The glass layer may be provided with regions having different appearances. The regions may be textured, may have coatings such as thin-film interference filter coatings formed from stacks of dielectric material having alternating indices of refraction, may have metal coating layers, and/or may have ink coating layers. Textured surfaces may be formed on thin glass layers and polymer films that are coupled to the glass layer. A glass layer may be formed from a pair of coupled glass layers. The coupled layers may have one or more recesses or other structures to visually distinguish different regions of the glass layer.
    Type: Grant
    Filed: April 8, 2022
    Date of Patent: January 2, 2024
    Assignee: Apple Inc.
    Inventors: James R. Wilson, Christopher D. Prest, Marta M. Giachino, Matthew S. Rogers, Que Anh S. Nguyen
  • Publication number: 20230414500
    Abstract: Methods are provided for drying a particle. Specifically, there is provided a spray-dried diketopiperazine-insulin particle formulation having improved aerodynamic performance and in which the active agent is more stabile and efficiently delivered as compared to that of the lyophilized diketopiperazine-insulin formulation. The dry powders have utility as pharmaceutical formulations for pulmonary delivery.
    Type: Application
    Filed: September 12, 2023
    Publication date: December 28, 2023
    Inventors: Bryan R. Wilson, Marshall Grant
  • Patent number: 11851030
    Abstract: Various embodiments relate to sensing defects associated with a window. Furthermore, various embodiments relate to performing image processing to produce a corrected image of a scene based at least partly on data corresponding to the detected defects. In some examples, one or more lighting modules may be used to illuminate the window to facilitate detection of the defects by one or more sensor devices.
    Type: Grant
    Filed: May 26, 2022
    Date of Patent: December 26, 2023
    Assignee: Apple Inc.
    Inventors: Clarisse Mazuir, Malcolm J. Northcott, Jack E. Graves, James R. Wilson, Christopher D. Jones, Martin Melcher
  • Patent number: 11849554
    Abstract: Textured cover assemblies for electronic devices are disclosed. The textured cover assemblies may provide a combination of optical and tactile properties to the electronic devices. In some cases, a textured cover assembly may be provided over decorative coating.
    Type: Grant
    Filed: June 17, 2022
    Date of Patent: December 19, 2023
    Assignee: APPLE INC.
    Inventors: Andi M. Limarga, James R. Wilson, Matthew S. Rogers, Que Anh S. Nguyen, Bijumon Varkey
  • Publication number: 20230402636
    Abstract: The present disclosure relates generally to a carbon-neutral process for the generation of carbon-neutral hydrogen and carbon-neutral electricity. More specifically, the present disclosure relates to compositions, methods and apparatus employing a carbon-neutral process for generating electricity employing a liquid organic hydrogen carrier (LOHC) for supplying hydrogen for generating the carbon neutral electricity. The present disclosure also relates more specifically to carbon-neutral compositions consisting of liquid organic hydrogen carriers used for supplying hydrogen to generate electricity that may be regenerated in a carbon-neutral process using an apparatus with a net zero atmospheric emission of carbon oxides.
    Type: Application
    Filed: June 7, 2023
    Publication date: December 14, 2023
    Applicant: The Claire Technologies Corporation
    Inventors: Paul A. Allinson, Robert P. Hohmann, Curtis L. Munson, Dennis J. O'Rear, Steven F. Sciamanna, William L. Schinski, Charles R. Wilson, Alan W. Klaassen
  • Patent number: 11833978
    Abstract: A sensing system that includes an optical,sensor and a sensing window. The optical sensor is configured to sense with electromagnetic radiation an environment. The sensing window is coupled to a structure, such that the electromagnetic radiation passes therethrough from the environment to the optical sensor to be sensed thereby. The sensing window includes an inner side that faces toward the optical sensor and an outer side that faces away from the optical sensor. The outer side includes a superhydrophobic surface that is in fluidic communication with the environment.
    Type: Grant
    Filed: September 15, 2021
    Date of Patent: December 5, 2023
    Assignee: APPLE INC.
    Inventors: James R. Wilson, Arthur Y. Zhang
  • Publication number: 20230381265
    Abstract: The invention provides formulations for oral delivery of a therapeutic wherein the formulation comprises a kappa opioid receptor agonist, an oligosaccharide stabilizing agent and an optional absorption enhancer. The kappa opioid receptor agonist may be coated with, embedded in or mixed with an oligosaccharide, such as trehalose. Also provided are capsules containing the oral formulations of the kappa opioid receptor agonists, the oligosaccharide and the absorption enhancer of the invention. The invention further provides methods of manufacture of the formulations and methods of their use for the prophylaxis, inhibition and treatment of variety of kappa opioid receptor-associated diseases and conditions such as pain, pruritus and inflammation. The methods of use include administering to the mammal the formulation of the kappa opioid receptor agonist, oligosaccharide and optional absorption enhancers.
    Type: Application
    Filed: May 30, 2023
    Publication date: November 30, 2023
    Applicant: Cara Therapeutics, Inc.
    Inventors: Bryan R. WILSON, Stephen J. O'CONNOR
  • Publication number: 20230384350
    Abstract: A voltage sensor for sensing an AC voltage of a HV/MV power conductor comprises a capacitive voltage divider for sensing the AC voltage having one or more high-voltage capacitors electrically connected in series with each other and a low-voltage portion comprising one or more low-voltage capacitors electrically connected with each other between the high-voltage portion and electrical ground. The voltage divider also comprises a signal contact, electrically arranged between the high-voltage portion and the low-voltage portion, for providing a signal voltage indicative of the AC voltage. The low-voltage portion further comprises a plurality of electrically actuated adjustable impedance elements configured to adjust the common overall impedance of the low-voltage portion towards a desired impedance.
    Type: Application
    Filed: May 22, 2023
    Publication date: November 30, 2023
    Inventors: Mark Gravermann, Gunther A. J. Stollwerck, Jens Weichold, Christine B. Bund, Mirco Gunjaca, Rainer Reeken, Martin A. Milek, Sebastian Eggert-Richter, Joerg Hahn, Michael H. Stalder, Christian Weinmann, Holger J. Kurzhals, Christopher R. Wilson
  • Publication number: 20230383250
    Abstract: Production and use of novel therapeutic cells, called T-Vehicles, in the allogeneic Adoptive Cell Therapy setting allows a wide range of therapeutic benefits to accrue with minimal or no risk of GVHD. T-Vehicles are created from donor T cells that are altered to contain therapeutic attributes that do not include their native antigen receptors and can deliver therapeutic benefits irrelevant of their native antigen specificity. T-Vehicles can possess highly restricted native antigen specificity that renders them unable to recognize antigens present on normal cells and incapable of initiating GVHD, making them ideal transport vehicles to deliver various therapeutic attributes in vivo. In essence, production and use of T-Vehicles is a paradigm shift that opens the door to therapeutic application of T cells in ways not previously contemplated, independent of whether or not there is an HLA match between the donor and the recipient.
    Type: Application
    Filed: May 17, 2023
    Publication date: November 30, 2023
    Inventors: Juan F. Vera, Cliona M. Rooney, Ann M. Leen, John R. Wilson
  • Publication number: 20230377687
    Abstract: The present disclosure relates, generally, to nucleotide sequence data and, more particularly, to computer files and methods supporting forensic DNA analysis. In one illustrative embodiment, a method may comprise identifying a locus corresponding to each item of short tandem repeat (STR) profiling data stored in an existing computer file, wherein the STR profiling data stored in the existing computer file is repeat-based and/or length-based; identifying start and stop coordinates of an STR region of the corresponding locus for each item of STR profiling data stored in the existing computer file; creating an ambiguous text string corresponding to each item of STR profiling data stored in the existing computer file, wherein each ambiguous text string consists of a sequence of ambiguous characters extending from the start coordinate to the stop coordinate identified for the corresponding item of STR profiling data; and storing each ambiguous text string in a sequence-based computer file.
    Type: Application
    Filed: April 17, 2023
    Publication date: November 23, 2023
    Inventor: Mark R. WILSON
  • Patent number: 11821002
    Abstract: An improved method of culturing cells for cell therapy applications that includes growing desired cells in the presence of antigen-presenting cells and/or feeder cells and with medium volume to surface area ratio of up to 1 ml/cm2 if the growth surface is not comprised of gas permeable material and up to 2 ml/cm2 if the growth surface is comprised of gas permeable material. The desired cells are at a surface density of less than 0.5×106 cells/cm2 at the onset of a production cycle, and the surface density of the desired cells plus the surface density of the antigen presenting cells and/or feeder cells are at least about 1.25×105 cells/cm2.
    Type: Grant
    Filed: March 7, 2022
    Date of Patent: November 21, 2023
    Assignees: Baylor College of Medicine, Wilson Wolf Manufacturing
    Inventors: Juan F. Vera, Cliona M. Rooney, Ann M. Leen, John R. Wilson