Abstract: Systems, devices and methods for model rocketry are provided. According to some aspects, new forms of model rocket nose cones, other model rocket components, and methods for their use, are provided. A new form of reversibly-divisible nose cone is provided, including a plurality of housing sections forming an interior payload section and, in some embodiments, including a locking mechanism(s) configured to hold the plurality of housing sections together during the initial phases of flight. In some embodiments, such a locking mechanism is unlocked, and the housing sections are separated, at least in part, in an ejection phase of model rocket flight. In some embodiments, such a locking mechanism is unlocked, at least in part, by increased air resistance and tension from shock cord(s) of a model rocket. Shock cord mounting arms are provided, including eyelet(s), mounted at an angle to a trailing surface of the nose cone.

Abstract: Fullerene compounds and formulations are taught as useful in reducing oxidative stress in an organism because of their antioxidant properties and REDOX balance (homeostasis) properties.

Abstract: A configuration of a direct drive lawnmower spindle assembly to protect sensitive electric motor components is provided. A spindle shaft of the spindle assembly is supported by upper and lower bearings. An upper end of the spindle shaft is mounted to a rotor of the electric motor and a lower end of the spindle shaft extends through the clearance opening. The lower bearing is supported by a lower bearing carrier that is mounted to the bottom of the spindle housing. The lower bearing can be serviced by removing the lower bearing carrier. A clearance gap between the spindle shaft and the clearance opening is sufficiently small to limit spindle shaft tipping to a degree that will not damage the motor. The invention also provides a friction coupling system for coupling a blade with the rotating spindle shaft.

Abstract: Improved cell culture devices and related methods that overcome the limitations of prior devices and methods, by creating devices that can integrate a variety of novel attributes. These various attributes include the use of gas permeable material and medium volumes that exceed conventional devices as well as compartments that can facilitate the long term study of high density cultures with reduced disruption of the culture environment, the ability to study the migration of items of interest including substances such as chemokine, track the movement of cells, and monitor cell to cell interactions.

Abstract: A container includes a cup and a lid. The lid is adapted to mate with a brim included in the cup to close a top aperture opening into an interior liquid-storage region formed in the cup.

Abstract: An electronic device may include electrical components and other components mounted within an interior of a housing. The device may have a display on a front face of the device and may have a glass layer that forms a housing wall on a rear face of the device. The glass housing wall may be provided with regions having different appearances. The regions may be textured, may have coatings such as thin-film interference filter coatings formed from stacks of dielectric material having alternating indices of refraction, may have metal coating layers, and/or may have ink coating layers. Textured surfaces, cavities, coatings, and other decoration may be embedded in glass structures that are joined with chemical bonds at diffusion-bonding interfaces.

Abstract: The invention provides formulations for oral delivery of a therapeutic agent wherein the formulation comprises a kappa opioid receptor agonist and an absorption enhancer, the absorption enhancer includes a medium chain fatty acid or a salt of a medium chain fatty acid; and a medium chain fatty acid glyceride. The kappa opioid receptor agonist may be embedded in an oligosaccharide, such as trehalose. Also provided are capsules containing the oral formulations of the kappa opioid receptor agonists and the absorption enhancer of the invention and methods use of these formulations for the prophylaxis and treatment of variety of kappa opioid receptor-associated diseases and conditions such as pain, pruritus and inflammation; the method comprising administering to the mammal the formulation comprising the kappa opioid receptor agonist and an absorption enhancer.

Abstract: Provided herein are combination therapies for the treatment of pathological conditions, such as cancer, using MEK antagonists.

Abstract: The lubrication device delivers a lubricant to the perforating device which provides intermittently spaced cuts to a moving web, also referred to as perforations. The lubrication device includes a retaining member, a plenum, and a comb having a plurality of comb channels. The plenum and the plurality of comb channels are in fluid communication with one another and deliver a lubricant to the perforating device. Lubrication of the perforating device in this manner may improve knife life, perforation quality and web handling.

Abstract: A ceramic composite article includes a substrate including a matrix of ceramic material defining a network of interstitial regions and a transparent material occupying at least some of the interstitial regions of the substrate. The transparent material can have a melting point lower than a melting point of the ceramic material. The matrix of ceramic material can be formed by a 3D printing process.

Abstract: An electronic device including an optical component and an enclosure comprising a glass ceramic region is disclosed. The optical properties of the glass ceramic region and the positioning of the glass ceramic region with respect to the optical component can affect the performance of the optical component, the visual appearance of the optical component, or both.

Abstract: The present disclosure relates, generally, to nucleotide sequence data and, more particularly, to computer files and methods supporting forensic DNA analysis. In one illustrative embodiment, a method may comprise identifying a locus corresponding to each item of short tandem repeat (STR) profiling data stored in an existing computer file, wherein the STR profiling data stored in the existing computer file is repeat-based and/or length-based; identifying start and stop coordinates of an STR region of the corresponding locus for each item of STR profiling data stored in the existing computer file; creating an ambiguous text string corresponding to each item of STR profiling data stored in the existing computer file, wherein each ambiguous text string consists of a sequence of ambiguous characters extending from the start coordinate to the stop coordinate identified for the corresponding item of STR profiling data; and storing each ambiguous text string in a sequence-based computer file.

Abstract: An automated computerized trading system is provided wherein a decentralized autonomous organization (DAO) includes a wallet having blockchain-based, smart-contract controlled cryptoassets associated with a commodity. The DAO receives data infeed from Application Programming Interfaces (APIs) from the blockchain to obtain cryptoasset price data and from an exchange to obtain commodity price data. The DAO stores commodity price and cryptoasset price spread targets and automatically initiates trading activity based on the price spread targets. A governance smart contract automatically distributes governance cryptoassets to public wallets that have contributed the crytpoassets to the DAO wallet.

Abstract: In selected embodiments a recommendation generator builds a network of interrelationships between venues, reviewers and users based on their attributes and reviewer and user reviews of the venues. Each interrelationship or link may be positive or negative and may accumulate with other links (or anti-links) to provide nodal links the strength of which are based on commonality of attributes among the linked nodes and/or common preferences that one node, such as a reviewer, expresses for other nodes, such as venues. The links may be first order (based on a direct relationship between, for instance, a reviewer and a venue) or higher order (based on, for instance, the fact that two venue are both liked by a given reviewer). The recommendation engine in certain embodiments determines recommended venues based on user attributes and venue preferences by aggregating the link matrices and determining the venues which are most strongly coupled to the user.

Abstract: Processes of polymerizing olefin monomers using catalyst systems and catalysts systems that include a procatalyst having a structure according to formula (I).

Abstract: A glass sheet having asymmetric chemical strengthening is disclosed and described. The examples described herein are directed to a cover glass for an electronic device and other glass components that may be used as enclosure elements or may form an enclosure. Within the glass component, localized compressive stress regions may be formed on opposite sides of the glass component, which may help arrest or redirect propagating cracks or defects in the glass. The opposing compressive stress regions may also help maintain the overall flatness of the component while increasing strength and/or impact resistance of the component.

Abstract: Processes of polymerizing olefin monomers using catalyst systems and catalysts systems that include a procatalyst having a structure according to formula (I):

Abstract: Some embodiments include an integrated assembly having a first deck with first memory cells arranged in first tiers disposed one atop another, and having a second deck over the first deck and with second memory cells arranged in second tiers disposed one atop another. Cell-material-pillars pass through the first and second decks. The cell-material-pillars have first inter-deck inflections associated with a boundary between the first and second decks. The cell-material-pillars are arranged within a configuration which includes a first memory-block-region and a second memory-block-region. A panel is between the first and second memory-block-regions. The panel has a second inter-deck inflection associated with the boundary between the first and second decks. Some embodiments include methods of forming integrated assemblies.

Abstract: The present invention encompasses methods and compositions for the generation and use of cytotoxic T lymphocytes that target multiple viruses or that are specific for multiple tumor antigens. In specific embodiments, the generation methods employ use of certain cytokines to promote proliferation and reduce cell death in an activated T cell population and/or that employ a particular bioreactor having a gas permeable membrane.

Abstract: The invention relates to oligomerization of olefins, such as ethylene, to higher olefins, such as a mixture of 1-hexene and 1-octene, using a catalyst system that comprises a) a source of chromium b) one or more activators and c) a phosphacycle-containing ligating compound. Additionally, the invention relates to a phosphacycle-containing ligating compound and a process for making said compound.