Abstract: According to various embodiments, an array of elements forms an artificially-structured material. The artificially-structured material can also include an array of tuning mechanisms included as part of the array of elements that are configured to change material properties of the artificially-structured material on a per-element basis. The tuning mechanisms can change the material properties of the artificially-structured material by changing operational properties of the elements in the array of elements on a per-element basis based on one or a combination of stimuli detected by sensors included in the array of tuning mechanisms, programmable circuit modules included as part of the array of tuning mechanisms, data stored at individual data stores included as part of the array of tuning mechanisms, and communications transmitted through interconnects included as part of the array of elements.

Abstract: A continuously variable nozzle system includes a nozzle body (5) with an inlet and an outlet. A conduit is defined between the inlet and the outlet by a series connection of components which includes a flow meter (10). The flow meter (10) has a chamber (83) with internal helical splines (82) that are configured to interact with a spray liquid passing through the chamber (83) and create a cyclone-like effect. A sphere (52) is located inside the chamber (83) for free movement along a circular path (106). A sensor is located outside of the chamber (83) and configured to detect motion of the sphere (52) and generate an output (9) signal in response to detected motion.

Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.

Abstract: Devices, systems, and methods of the present disclosure are generally directed to facilitating user control of high-pressure flow of liquid for oral irrigation carried out as part of personal dental care. Such control over high-pressure flow may reduce the likelihood of errant spray of liquid outside of the user's mouth (e.g., onto mirrors, countertop surfaces, or the user's clothes). Such improved control over errant spraying may reduce the potential for frustration and, thus, may promote maintaining oral irrigation as part of a personal dental care routine. Further, or instead, through facilitating user control of high-pressure flow of liquid, the devices, systems, and methods of the present disclosure may improve the effectiveness and efficiency of self-administered oral irrigation in promoting a user's oral hygiene.

Abstract: A pedicle screw for insertion into a vertebra, the pedicle screw including: a head; a distal tip; a threaded portion extending at least partially between the head and the distal tip; and a radiographically visible element located at a predefined location on the threaded portion, where the head, the distal tip, and the threaded portion are formed of a metal or a metal alloy. Also disclosed is a corresponding system for insertion of a pedicle screw into a vertebra and a corresponding method for inserting a pedicle screw into a vertebra.

Abstract: A rectangular waveguide circulator consists of multiple sections that meet at a common junction where a tapered ferrite portion is disposed. A ferrite portion is disposed within a hollow space adjacent the common junction. The ferrite portion has a shape that includes an upper portion, a middle portion, and a lower portion, such that a cross sectional area of the upper portion is greater than a cross-sectional area of the middle portion, and such that a cross sectional area of the lower portion is greater than the cross-sectional area of the middle portion.

Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.

Abstract: A spray pattern monitoring system includes a spray sensor disposed proximate an outlet of a spray nozzle. The spray sensor has one or more optical sensors configured to emit directional light, such as laser pulses, towards the expected position of a liquid spray emitted from the nozzle. The spray sensor can detect the absence or presence of the liquid spray based on returns of the directional light to the optical sensor.

Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.

Abstract: Methods are provided for extracting bone marrow cells from bone obtained from deceased donors, for preparing the bone marrow for cryopreservation and for obtaining desired cells from cryopreserved and fresh bone marrow.

Abstract: Methods are provided for extracting bone marrow cells from bone obtained from deceased donors, for preparing the bone marrow for cryopreservation and for obtaining desired cells from cryopreserved and fresh bone marrow.

Abstract: A spray pattern monitoring system includes a spray sensor disposed proximate an outlet of a spray nozzle. The spray sensor has one or more optical sensors configured to emit directional light, such as laser pulses, towards the expected position of a liquid spray emitted from the nozzle. The spray sensor can detect the absence or presence of the liquid spray based on returns of the directional light to the optical sensor.

Abstract: A portable torque power tool is disclosed herein and includes: a motor to generate a turning force; a drive to transfer the turning force; a turning force multiplication mechanism assembly to multiply the turning force; a shifter assembly to shift the tool between a lower speed/higher torque (LSHT) mode and a higher speed/lower torque (HSLT) mode; a torque transducer to measure torque output; wherein torque output is controlled by the torque transducer in LSHT mode; and wherein torque output is controlled by motor current in HSLT mode. In one embodiment of the present application, the torque transducer is a wireless torque transducer assembly formed at or near an output of a housing of the turning force multiplication assembly to improve measurement accuracy of torque output.

Abstract: A drilling fluid conditioning system for a well system includes a return conduit configured to receive drilling fluid recirculated from a wellbore of the well system, a drilling fluid pre-chilling system in fluid communication with and downstream from the return conduit, wherein the drilling fluid pre-chilling system includes a cooler configured to transfer heat from the drilling fluid to a heat sink, and a solids control system in fluid communication with and downstream from the drilling fluid pre-chilling system, wherein the solids control system is configured to separate at least some solids from the drilling fluid.

Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.

Abstract: Methods are provided for extracting bone marrow cells from bone obtained from deceased donors, for preparing the bone marrow for cryopreservation and for obtaining desired cells from cryopreserved and fresh bone marrow.

Abstract: A method, system and computer program product for sharing resources among remote repositories. In a shared file system, a resource identifier and metadata are created for a resource, where the resource identifier is stored in a lock file in a shared volume accessible by the remote repositories. The lock file is then released in response to distributing the associated resource to the remote repositories. Alternatively, in a peer-to-peer system, a request is received to create, read, update or delete a resource stored in a content repository. A resource name, a resource version and/or a resource fingerprint are received in connection with the request to create, read, update or delete the resource in the content repository. A determination is then made as to whether the received resource name, resource version and/or resource fingerprint matches the respective resource name, resource version and/or resource fingerprint stored in a node graph for the resource.

Abstract: The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, Ra, Rb, Q1, and Q2 are defined in the specification. The invention also comprises a method of treating or ameliorating a ROR-?-t mediated syndrome, disorder or disease, including wherein the syndrome, disorder or disease is selected from the group consisting of rheumatoid arthritis, psoriatic arthritis, and psoriasis. The invention also comprises a method of modulating ROR?t activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula I.

Abstract: A spray nozzle for an agricultural sprayer includes a first actively controlled valve configured to control flow through the spray nozzle. A first pressure sensor is disposed upstream of the valve and a second pressure sensor is disposed downstream of the valve. The position of a valve member of the valve can be sensed, and a size of a restrictive orifice defined by the valve can be determined based on the sensed position of the valve member. A controller is configured to determine a flow rate through the valve based on a difference between a first pressure reading from the first pressure sensor and a second pressure reading from the second pressure sensor.

Abstract: A hydraulic spray nozzle for an agricultural implement includes at least one of a bleed valve and an annular valve. The bleed valve is configured to control flow of a bleed portion of the liquid provided to the nozzle for spraying. The bleed portion can be routed back to a supply tank for later use. The bleed valve can be an annular valve. A spray valve within the nozzle can also be an annular valve.