Abstract: Embodiments of a bumper assembly includes a reinforcement beam that extends in a vehicle lateral direction, the reinforcement beam including a front face that extends in the vehicle lateral direction and a rear face that is positioned rearward of and spaced apart from the front face in a vehicle longitudinal direction that is transverse to the vehicle lateral direction, and a front spacer member coupled to an outboard end of the front face of the reinforcement beam, the front spacer member including an end plate that extends between the front face and the rear face of the reinforcement beam and is positioned at least partially within the reinforcement beam.

Abstract: A tool for cutting a tie wrap bound about a wire bundle. The tool includes a body portion having a generally disc-shaped cutter and cutting edge. A shield covers one side of the cutter and defines first and second shield slots in communication with the cutting edge. A housing pivotally connected to the body portion covers the other side of the cutter and defines first and second housing slots that communicate with the cutting edge. The housing pivots between first, second, and third positions. In the first position, the first housing slot communicates with the first shield slot to expose the cutting edge for cutting purposes. In the second position, the first housing slot is out of communication with the first shield slot, thereby covering the cutting edge. And, in the third position, the second housing slot communicates with the second shield slot to expose the cutting edge.

Abstract: One embodiment of the present invention provides a system that facilitates reducing static power consumption of a processor. During operation, the system receives a signal indicating that instruction execution within the processor is to be temporarily halted. In response to this signal, the system halts an instruction-processing portion of the processor, and reduces the voltage supplied to the instruction-processing portion of the processor. Full voltage is maintained to a remaining portion of the processor, so that the remaining portion of the processor can continue to operate while the instruction-processing portion of the processor is in reduced power mode.

Abstract: The present disclosure is directed to a backwater valve assembly comprising a main valve body, a flapper sub-assembly, and a cap. The main valve body has an inner wall that can define a recess into which the flapper sub-assembly can be removably secured. The flapper sub-assembly includes at least one flapper element that can pivot between an open position, in which the flapper element allows fluid to flow through the backwater valve assembly, and a closed position, in which the flapper element prevents fluid from flowing in the opposite direction. The flapper sub-assembly can be removably coupled to the cap to allow the flapper sub-assembly and cap to be installed in or removed from the main valve body together as a unitary assembly.

Abstract: The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

Abstract: A tool for cutting a tie wrap bound about a wire bundle. The tool includes a body portion having a generally disc-shaped cutter and cutting edge. A shield covers one side of the cutter and defines first and second shield slots in communication with the cutting edge. A housing pivotally connected to the body portion covers the other side of the cutter and defines first and second housing slots that communicate with the cutting edge. The housing pivots between first, second, and third positions. In the first position, the first housing slot communicates with the first shield slot to expose the cutting edge for cutting purposes. In the second position, the first housing slot is out of communication with the first shield slot, thereby covering the cutting edge. And, in the third position, the second housing slot communicates with the second shield slot to expose the cutting edge.

Abstract: A stented valve including a stent structure including a generally tubular body portion having a first end, a second end, an interior area, a longitudinal axis, and a plurality of vertical wires extending generally parallel to the longitudinal axis around a periphery of the body portion, wherein the plurality of vertical wires includes multiple commissure wires and at least one structural wire positioned between adjacent commissure wires, and a plurality of V-shaped wire structures having a first end, a second end, and a peak between the first and second ends, wherein a first end of each V-shaped structure extends from a first vertical wire and a second end of each V-shaped structure extends from a second vertical wire that is adjacent to the first vertical wire, wherein each V-shaped structure is oriented so that its peak is facing in the same direction relative to the first and second ends of the body portion, and a valve structure including a plurality of leaflets attached to the stent structure within the

Abstract: Methods for treating joint diseases, disorders, and conditions, such as osteoarthritis, with a composition containing a therapeutically effective amount of tissue inhibitors of matrix metalloproteinases (TIMPs) are provided. The composition can contain TIMPs as part of amniotic fluid, or the TIMPs can be isolated from another source or recombinantly produced. The methods are particularly useful for treating osteoarthritis associated with degradation of articular cartilage by proteases. Also provided are methods of lubricating a joint, such as an osteoarthritic joint.

Abstract: The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.

Abstract: The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

Abstract: Vehicle structures for dissipating energy associated with a collision are described herein. In one embodiment, a vehicle includes a first side support extending in a vehicle longitudinal direction, a second side support extending in the vehicle longitudinal direction and spaced apart from the first side support in a vehicle lateral direction that is transverse to the vehicle longitudinal direction, and a cross-vehicle stabilizing structure extending between the first side support and the second side support, the cross-vehicle stabilizing structure including a first joint portion coupled to the first side support, the first joint portion including a stiffness-reducing portion positioned within a perimeter of the first joint portion, a second joint portion coupled to the second side support, and a cross-vehicle stabilizer portion coupled to the first joint portion and the second joint portion.

Abstract: A ladder guard to prevent access to a hunting ladder, includes: a ladder guard plate, including an inward protruding plate hook, that attaches to a rung of the ladder; at least two bracket apertures; and a bracket with upper and lower legs, each including a padlock aperture, such that the ladder guard attaches with the plate hook to an upper rung of the ladder; and the bracket locks the guard plate to a lower rung, with a padlock. Also disclosed is a ladder guard, including a ladder guard plate, with a plate cutout, ladder guard apertures, and a stabilizer bracket, including a connector plate with connector plate aperture, upper and lower flange portions, upper and lower flange extensions with extension apertures, such that the ladder guard is locked to a ladder using a padlock inserted through the extension apertures.

Abstract: Vehicles incorporating load-transferring hood hinge members are disclosed. In one embodiment, a vehicle includes an A-pillar portion, an upper side member coupled to the A-pillar portion and extending forward from the A-pillar portion in a vehicle longitudinal direction, and a dash panel coupled to the A-pillar portion and extending in a vehicle lateral direction that is transverse to the vehicle longitudinal direction. The vehicle also includes a hood hinge member that is coupled to the upper side member and positioned forward of the A-pillar portion. The hood hinge member includes an attachment portion that is coupled to the upper side member, a flange member that extends upward from the attachment portion, a hood attachment opening passing through the flange member, and a rearward-projecting protrusion having a distal surface that is positioned transverse to the flange member.

Abstract: A ladder guard to prevent access to a hunting ladder and other types of ladders, include: a ladder guard plate, further including a plate hook, configured as an inward protruding hook that attaches to a rung of the ladder; at least two bracket apertures; and a bracket; such that the bracket with upper and lower legs, each further comprising a pad lock aperture; such ladder guard plate attaches with the plate hook to an upper rung of the ladder; and the bracket locks the guard plate to a lower rung of the ladder, with a pad lock. Also disclosed is a ladder guard, including a plate hook and two bracket apertures, such that the ladder guard is locked to a ladder using an adjustable shackle padlock. The ladder guard can further include a plate cut-out, and can be painted with camouflage colors.

Abstract: Visco-supplement compositions derived from a transcellular fluid, such as human amniotic fluid, human aqueous humor fluid, or human vitreous fluid are described. Also described are methods for treating inflammatory conditions of the musculoskeletal system, such as joint inflammation, and methods of lubricating a joint using the described visco-supplement compositions.

Abstract: Vehicle structures for dissipating energy associated with a collision are described herein. In one embodiment, a vehicle includes a first side support extending in a vehicle longitudinal direction, a second side support extending in the vehicle longitudinal direction and spaced apart from the first side support in a vehicle lateral direction that is transverse to the vehicle longitudinal direction, and a cross-vehicle stabilizing structure extending between the first side support and the second side support, the cross-vehicle stabilizing structure including a first joint portion coupled to the first side support, the first joint portion including a stiffness-reducing portion positioned within a perimeter of the first joint portion, a second joint portion coupled to the second side support, and a cross-vehicle stabilizer portion coupled to the first joint portion and the second joint portion.

Abstract: A polarizer includes a polarizer component having a top surface and an opposite bottom surface. The bottom surface is configured to couple to a color filter layer for a liquid crystal display. The polarizer also includes a transparent conducting layer disposed over the top surface. The transparent conducting layer being configured to electrically shield the LCD from a touch panel. The polarizer further includes a coating layer disposed over the transparent conducting layer.

Abstract: The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

Abstract: Vehicle structures for dissipating energy associated with a collision are described herein. In one embodiment, a vehicle includes a first side support extending in a vehicle longitudinal direction, a second side support extending in the vehicle longitudinal direction and spaced apart from the first side support in a vehicle lateral direction that is transverse to the vehicle longitudinal direction, and a cross-vehicle stabilizing structure extending between the first side support and the second side support, the cross-vehicle stabilizing structure including a first joint portion coupled to the first side support, the first joint portion including a stiffness-reducing portion positioned within a perimeter of the first joint portion, a second joint portion coupled to the second side support, and a cross-vehicle stabilizer portion coupled to the first joint portion and the second joint portion.

Abstract: A touch-screen display apparatus, the apparatus may include first and second sheets having opposed major surfaces and a size and shape defined by a periphery. The periphery may be defined by opposed ends and opposed edges. The first and second sheets may each have a conductive pattern including a pair of opposed busbars and a plurality of traces electrically coupled to, and extending between, corresponding pairs of opposed busbars. The transparent force sensing (TFS) sheet may have opposed major surfaces and a variable resistance which is related to a force exerted upon one or more of its major surfaces. The TFS sheet may be situated between the first and second sheets. The apparatus may also include one or more separation portions situated between the TFS sheet and the first or second sheet to bias the TFS sheet apart from the first or second sheet.