Abstract: A method including receiving a natural language query from a user interface of a chatbot. The method also includes generating an input vector by performing vectorization on the natural language query. The method also includes inputting the input vector to a shallow-deep classifier. The shallow-deep learning classifier includes a classification machine learning model programmed to classify the input vector as being one of a shallow machine learning classification problem and a deep machine learning classification problem. The method also includes outputting, by the shallow-deep classifier, an output label. The output label includes one of the shallow machine learning classification problem and the deep machine learning classification problem.

Abstract: The present invention relates to novel protein pores and their uses in analyte detection and characterisation. The invention particularly relates to an isolated pore complex formed by a CsgG-like pore and a modified CsgF peptide, or a homologue or mutant thereof, thereby incorporating an additional channel constriction or reader head in the nanopore. The invention further relates to a transmembrane pore complex and methods for production of the pore complex and for use in molecular sensing and nucleic acid sequencing applications.

Abstract: Methods and systems are provided for data synchronization. In one example, a method for synchronizing data between an agent and a core includes sending, from the agent, a request to the core identifying a data subset to be synchronized, the request further including a fingerprint for each block of data in the data subset; receiving, at the agent, a response from the core identifying a block of mismatched data between the core and the agent; fetching a fingerprint for each record of the identified block of mismatched data and creating a fingerprint of the block based on the fetched fingerprints; sending, from the agent, a request to the core including the fingerprint of the block; and receiving, at the agent, one or more records from the core identified via a comparison of fingerprints of the one or more records.

Abstract: The invention relates to mutant forms of lysenin. The invention also relates to analyte characterisation using the mutant forms of lysenin.

Abstract: The invention provides an ocular composition comprising: 99 to 60% (w/w) of a photopolymerizable composition selected from the group of fragments or monomers consisting of polyalkylene glycol diacrylate and polyalkylene glycol dimethacrylate, wherein the photopolymerizable composition has a molecular weight in the range of 100 to 20,000 Dalton; a biodegradable polymer selected from the group consisting of aliphatic polyester-based polyurethanes, polylactides, polycaprolactones, polyorthoesters and mixtures, copolymers, and block copolymers thereof; a photoinitiator; and a therapeutic agent. The composition can be used to form an ocular implant and an in situ ocular implant.

Abstract: A graphene-based broadband radiation sensor and methods for operation thereof are disclosed. The radiation sensor includes an electrical signal path for carrying electrical signals and one or more resonance structures connected to the electrical signal path. Each resonance structure includes a resonator having a resonant frequency. Each resonance structure also includes a graphene junction connected in series with the resonator, the graphene junction including a graphene layer and having an impedance that is dependent on a temperature of the graphene layer. Each resonance structure further includes a heating element that is thermally coupled to the graphene layer and is configured to receive an incident photon, where the temperature of the graphene layer increases in response to the heating element receiving the incident photon.

Abstract: Techniques are disclosed relating to methods that include receiving an indication of an access by a user to a web page that includes a beacon, and calculating a readiness score for triggering the beacon. The methods may also include determining, based on the readiness score, whether to perform a client-side or server-side triggering of the beacon. The triggering causes data associated with the access to be transmitted to a third-party computer system.

Abstract: Disclosed herein are cameras and image sensors, and electronic devices containing them, having pixel arrays operable both for obtaining images and detecting flicker in ambient light. For flicker detection, such as prior to image capture, light-generated current from a set of pixels of the pixel array is received at a transimpedance amplifier (TIA) that is formed in a common semiconductor substrate with the pixel array. An output signal of the TIA is digitized and signal processed to detect the flicker in the ambient light. Also disclosed are image sensors having pixel arrays with an embedded modulated light source. The modulated light source may be used for proximity detection, either by time-of-flight or intensity variation of reflected light.

Abstract: The present disclosure generally relates to wireless communication. Some aspects of the present disclosure include systems and techniques for device authentication. For example, an apparatus for wireless communication may receive, via a microphone, an audio signal from a second device. The apparatus may decode the audio signal to determine an encoded value. The apparatus may further determine that the audio signal is associated with the second device based on the encoded value. The apparatus may further establish a connection to the second device based on determining that the audio signal is associated with the second device.

Abstract: Systems and methods for improving power usage of a wireless device are disclosed. The wireless device includes a memory; and at least one processor communicatively coupled to the memory, the at least one processor configured to: determine a change in ambient light received by the wireless device; determine a position of the wireless device; activate a low power image sensor based on at least one of the change in the ambient light or the position of the wireless device; detect a face using the low power image sensor; and turn on a display of the wireless device based on a user face being the face detected.

Abstract: Provided herein relate to modified or mutant forms of secretin and compositions comprising the same. In particular, the modified or mutant forms of secretin permits efficient capture and/or translocation of an analyte through the modified or mutant secretin nanopores. Methods for using unmodified secretin or the modified or mutant forms of secretin and compositions, for example, for characterizing an analyte, e.g., a target polynucleotide, are also provided.

Abstract: Systems and methods for population health surveillance utilizing a network of smart thermometers is provided. Based on the geolocated user data provided by the smart thermometers, contagious illness can be forecasted for various population nodes. Population nodes can be provided at various levels of granularity. Geographic or population specific early warning signals can be generated based on detected outbreaks of contagious illness.

Abstract: Provided herein relate to modified or mutant forms of secretin and compositions comprising the same. In particular, the modified or mutant forms of secretin permits efficient capture and/or translocation of an analyte through the modified or mutant secretin nanopores. Methods for using unmodified secretin or the modified or mutant forms of secretin and compositions, for example, for characterizing an analyte, e.g., a target polynucleotide, are also provided.

Abstract: Disclosed is a system and a method to facilitate incentivization to decentralized app (DApp) users and validators in a blockchain network. The method to facilitate incentivization includes determining an eligibility criterion for incentive distribution to a set of client nodes based on a count of minted nodes added to a network by the set of client nodes and obtaining a set of eligible client nodes from the set of client nodes based on the determined eligibility criterion. The method to facilitate incentivization further includes computing an incentive amount for each eligible client node of the set of client nodes respectively, computing an incentive amount for each validator node of a set of validator nodes respectively and transferring the computed incentive amounts specific to each eligible client node and every validator node, to each eligible client node and every validator node respectively.

Abstract: There are provided systems and methods for a physical card having one or more location detection modules A physical payment card may include one or more components to limit card reading of card data stored to the card using a location detection chip. The location detection chip may receive power from a source when inserted to a card reader, and may then determine a location of the card, such as a coordinate location of the card or nearby detected device. The location detection chip may determine if this location or device matches authorized locations stored in a memory of the card. If it does, power may be provided to a card chip of the card. The card chip of the card reads card data from a memory of the card and may then output the card data to the card reader.

Abstract: The present invention relates to a method for growing plants, wherein said method comprises supplying plant defence inducers (PDI) in particular for the purpose of protecting plants against pests without negatively affecting their growth and development.

Abstract: Systems and methods for population health surveillance utilizing a network of smart thermometers is provided. Based on the geolocated user data provided by the smart thermometers, contagious illness can be forecasted for various population nodes. Population nodes can be provided at various levels of granularity. Geographic or population specific early warning signals can be generated based on detected outbreaks of contagious illness.

Abstract: The present invention relates to an ocular composition comprising a) at least 0.1% w/w of a therapeutic agent; b) 5 to 95% w/w of a photopolymerizable composition comprising 3 to 70% w/w of one or more compounds of formula I: (I) wherein R1 is hydrogen or a linear or branched C1-C3 alkyl; R2 is an acrylate or methacrylate group; n is 2 or 3 and m is equal or greater than 1, the weight percentage of the one or more compounds of formula I being based on the total weight of the photopolymerizable composition; c) 0.

Abstract: The present invention relates to a method for growing plants, wherein said method comprises supplying to at least part of a plant or a seed at least one beta-amino carbonyl compound.

Abstract: Provided is a label-free, single biological cell dielectric spectroscopy method, including the steps of: translocating a biological cell through a micropore or channel embedded in a substrate and interfaced with a coplanar waveguide while the biological cell experiences at least one RF field of at least 700 MHz provided via an RF input port to the coplanar waveguide; performing a time domain measurement of at least one RF signal reflected from or transmitted to a device under test (DUT); and determining an amplitude change and a phase change based on the reflected or transmitted at least one RF signal due to the translocating biological cell to determine an internal state or a morphological state of the biological cell. Also disclosed herein are devices for performing the dielectric spectroscopy method.