Abstract: The present invention relates to extended release pharmaceutical compositions of paliperidone and process of preparation thereof.

Abstract: A CMOS structure is formed on a semiconductor substrate that includes first and second regions having an nFET and a pFET respectively formed thereon. Each nFET and pFET device is provided with a gate, a source and drain, and a channel formed on the substrate. A high permittivity dielectric layer formed on top of the channel is superimposed to the permittivity dielectric layer. The pFET gate includes a thick metal nitride alloy layer or rich metal nitride alloy or carbon metal nitride layer that provides a controlled WF. Superimposed to the permittivity dielectric layer, the nFET gate is provided with a thin metal nitride alloy layer, enabling to control the WF. A metal deposition is formed on top of the respective nitride layers. The gate last approach characterized by having a high thermal budget smaller than 500° C. used for post metal deposition, following the dopant activation anneal.

Abstract: Sustained release formulations comprising donepezil, or its pharmaceutically acceptable salts, and methods of preparing the sustained release formulations.

Abstract: The invention relates to pharmaceutical compositions comprising multilayered multiple units and processes for the preparation thereof.

Abstract: A high bandwidth multi-stage microjet actuator. The actuator can produce relatively large amplitude flow disturbances over a broad range of frequencies. The disturbance frequency can be varied by altering the geometry of the device, altering the pressure ratio(s) within the device, and combinations of the two. The actuator has many potential applications, including noise abatement for jet aircraft, and flow control over a moving airfoil.

Abstract: Aspects of the present application relate to pharmaceutical formulations comprising a nonsteroidal anti-inflammatory drug, together with a proton pump inhibitor drug, to reduce the incidence of gastrointestinal complications associated with chronic therapy with a nonsteroidal anti-inflammatory drug. Specific aspects of the application relate to fixed dose combinations comprising aspirin, or a derivative thereof, and omeprazole or esomeprazole, or pharmaceutically acceptable salts, solvates, or hydrates thereof.

Abstract: An apparatus, system, and method are disclosed for processing a technology specific message. In one embodiment, a computer program product receives a message having a conventional header and a user-defined header that both conform to a predefined header format, each header comprising a header name and a value; identifies each header in the message based on the predefined header format; generates a header structure to store the header name and the value from each header; stores the header structure in a set of header structures of an extendable message business object; and passes the extendable message business object to an integration broker.

Abstract: The present invention relates to multilayered modified release formulation comprising amoxicillin and clavulanate, process of preparation thereof and method of treating bacterial infection using these formulations. The multilayered modified release formulation comprises: an immediate release layer comprising amoxicillin and clavulanate; and a slow release layer comprising amoxicillin and one or more release retarding agents; and one or more non-release controlling inert barrier layers placed in between the immediate release layer and the slow release layer and comprising one or more pharmaceutically acceptable excipients.

Abstract: A high bandwidth multi-stage microjet actuator. The actuator can produce relatively large amplitude flow disturbances over a broad range of frequencies. The disturbance frequency can be varied by altering the geometry of the device, altering the pressure ratio(s) within the device, and combinations of the two. The actuator has many potential applications, including noise abatement for jet aircraft, and flow control over a moving airfoil.

Abstract: The present invention relates to extended release tablets comprising a core which comprises of nisoldipine, a rate-controlling hydrophilic polymer and optionally, an enteric agent. Such tablets may also be coated with a release rate-controlling coating comprising of a hydrophobic polymer or enteric agent or combinations thereof, in particular ethylcellulose, and Eudragits.

Abstract: The present invention relates to an extended release dosage form of quetiapine wherein the dosage form comprises quetiapine and rate-controlling polymer selected from polyethylene oxide, sodium alginate and natural gum and combinations thereof. The dosage form may additionally comprise at least one water-insoluble polymer.

Abstract: The present invention relates to multiple unit extended release dosage forms of quetiapine for oral administration, wherein each unit comprises a core containing quetiapine and one or more of pharmaceutically acceptable excipients coated with a rate-controlling coating and process for the preparation thereof.

Abstract: The present invention relates to a process for preparing a pharmaceutical composition comprising carbamazepine that has a constant release profile.

Abstract: The present invention relates to controlled release oral dosage forms of galantamine or acceptable salts thereof and processes for the preparation thereof.

Abstract: An apparatus, system, and method are disclosed for intelligent polling support for Websphere JCA adapters based on the self-configuration characteristic of an autonomic computing model. The apparatus, system, and method maintain a set of statistical parameters across multiple poll cycles that are used to adjust polling parameters. The polling parameters control poll intervals and poll quantities. The polling parameters are adjusted based on historical event arrival rates.

Abstract: An apparatus, system, and method are disclosed for pattern-based archiving of business events on a middleware server. The method performs pattern-based archiving of business events on a middleware server by: interpreting a user-specified naming pattern for labeling event archive structures, each event archive structure corresponding to an event; detecting the occurrence of a middleware event triggered by a business process; generating an archive filename based on the user-specified naming pattern, the filename comprising data from the event; and providing the filename to an event storage module for saving an archive file with the filename. The archiving method allows users to review archived files such that the filename provides a context for the archive document, and users can more easily find specific documents.

Abstract: An apparatus, system, and method are disclosed for processing a technology specific message. In one embodiment, a computer program product receives a message having a conventional header and a user-defined header that both conform to a predefined header format, each header comprising a header name and a value; identifies each header in the message based on the predefined header format; generates a header structure to store the header name and the value from each header; stores the header structure in a set of header structures of an extendable message business object; and passes the extendable message business object to an integration broker.

Abstract: The invention features a thermal and/or light-protective container assembly that includes a flexible outer and inner layer, as well as a thermoregulatory material disposed between said outer and inner layers. In general, the invention is directed to a thermal and/or light-protective container assembly, such as a form-fitting sleeve, that includes a flexible layered wall having an opened end and a contiguous closed end, wherein the wall defines a centrally located cavity. The wall further includes an outer layer and an inner layer, wherein uniformly disposed between the outer and inner layers is a thermoregulatory material that is configured for insulating an object, and/or for transferring heat or cold to the object, and/or maintaining the temperature of the object disposed within the defined cavity of the sleeve.

Abstract: Provided is a battery comprising a first compartment, a second compartment and a barrier separating the first and second compartments, wherein the barrier comprises a proton transporting moiety.

Abstract: A pharmaceutical composition useful for sustained/extended release of a therapeutically active ingredient to an environment of use, said composition comprises a tablet core composition consists of a therapeutically active ingredient that is weakly acidic in nature and has a limited solubility in the aqueous environment, said the therapeutically active ingredient is in immediate contact with the agents that are capable of improving the solubility of the agent within the core, for e.g., by changing the micro environmental pH of the core and the tablet core is surrounded by a release rate controlling membrane consisting of a semi-permeable membrane forming polymer, permeable membrane forming polymer, and at least one plasticizer capable of modulating the film formation properties of the polymers.