Abstract: An illustrative storage management appliance is interposed between client computing devices and one or more cloud storage resources. The appliance uses cloud storage resources in conjunction with a network attached storage device configured within the appliance to provide to the client computing devices seemingly unlimited network attached storage on respective network shares. The storage management appliance monitors data objects on the network shares and when a data object meets one or more criteria for archiving, the storage management appliance archives the data object to a cloud storage resource and replaces it with a stub and preview image on the network share. When access to the stub and/or preview image is detected, the storage management appliance restores the data object from the cloud storage resource. The criteria for archiving flexibly allow individual data objects to be archived to cloud storage without archiving frequently-accessed “neighboring” data objects on the same network share.

Abstract: A computer-implemented method for generating a financial product that is configured to be used for one or more payment transactions. The method includes receiving a selection of a plurality of core accounts for providing financial backing for the financial product, and generating the financial product based on one or more control parameters that define use restrictions for the financial product.

Abstract: Sub-systems of air handling units in infrastructures face unresolved problem of conflict in the rules that activate in a contradictory manner at the same time resulting in sub-optimal performance of the subsystems. The present disclosure provides a system and method for optimizing performance parameters of air handling units in infrastructures. Rule sets having conflicting conditions are identified after verification of rules which are specific to air handling units. Further, frequency of the rule sets having conflicting conditions is determined to generate a ranked list of the rule sets having conflicting conditions. Another ranking procedure is implemented for the rules comprised in the ranked list of the rule sets having conflicting conditions. The system dynamically optimizes one or more parameters specific to the performance criteria based on the ranking of rules.

Abstract: The present invention relates generally to glycoconjugates comprising a saccharide covalently conjugated to a carrier protein through a spacer containing ((2-oxoethyl)thio)). In an aspect the invention provides oxo-eT linked glycoconjugates comprising a saccharide covalently conjugated to a carrier protein through a ((2-oxoethyl)thio) spacer having the formula (I): wherein: A is a group (C?X)m wherein X is S or O and m is 0 or 1; B is a bond, O, or CH2; and when m is 0, B can also be (C?O); R is a C2-C16 alkylene, C2-C16 heteroakylene, NH—C(?O)—C2-C16 alkylene, or NH—C(?O)—C2-C16 heteroakylene, wherein said alkylene and heteroalkylene are optionally substituted by 1, 2 or 3 groups independently selected from COOR? where R? is selected from H, methyl, ethyl or propyl. The invention further relates to immunogenic compositions comprising such glycoconjugates, and to methods for the preparation and use of such glycoconjugates and immunogenic compositions.

Abstract: The present invention relates to a stable liquid pharmaceutical composition of pemetrexed for parenteral administration. The invention provides composition comprising pemetrexed diacid, an organic amine and cyclodextrin. The composition may further comprise an inert gas. The composition can be ready to use infusion solution of pemetrexed diacid or liquid concentrate formulation to be diluted before administration to the patient. The present invention further relates to a process for manufacturing the compositions as well as use of the compositions of the invention for the treatment of malignant pleural mesothelioma and non-small cell lung cancer.

Abstract: Systems, methods and computer software are disclosed for providing base station and Remote Radio Head (RRH) functionality. In one embodiment, a method is disclosed, the method for providing base station and Remote Radio Head (RRH) functionality in a base station, comprising: providing a baseband card; providing a radio head, the radio head coupled to the baseband card by way of an interface; and switching, under the control of a processor, between use of the baseband card and use of an external baseband unit for controlling the radio head, the external baseband unit used via a Common Public Radio Interface (CPRI) port, thereby providing dual base station and remote radio head functionality.

Abstract: A manifold for domestic water purification systems having flow paths that can be redirected without having to change the physical structure of the manifold or water purification system—a structure to assist with proper installation and stabilization of specific filter cartridges, a memory reader for processing data relating to the state of the filter cartridges, a hinge system to allow for easier installation/removal of new and replacement filter cartridges, and a flow path structure to assist in adding accessories to the water filtration system without requiring a modification to the manifold structure.

Abstract: The present invention provides crystalline Roxadustat Form-?, crystalline Roxadustat Form-?, process for the preparation of crystalline Roxadustat Form-?, crystalline Roxadustat Form-? and its pharmaceutical compositions thereof. The present invention also provides co-crystals of Roxadustat Form RLP, Roxadustat Form RNM and Roxadustat Form RU, process for their preparation and pharmaceutical composition thereof.

Abstract: An aerosol delivery device is provided. The aerosol delivery device includes terminals to connect a power source to the aerosol delivery device, an aerosol production component, and a buck-boost regulator circuit coupled to a load including the aerosol production component. The buck-boost regulator circuit includes a buck-boost controller to drive a plurality of power switches in a synchronous switching converter topology. The plurality of power switches includes a high-side power switch coupled between the power source and a switching node, and a low-side power switch coupled between the switching node and ground. The buck-boost regulator circuit also includes an inductor coupled between the switching node and the load. In buck mode, the buck-boost controller supplies pulse-width modulation signals to alternately turn on and off the high-side power switch and the low-side power switch on and off.

Abstract: A system and method are disclosed for managing snapshots of a distributed file system. In accordance with one implementation, a list of snapshots of a file system is presented to a user, where the snapshots include one or more active snapshots and one or more inactive snapshots. A request by the user to access one of the snapshots in the list is received. In response to determining that the requested snapshot is active, the user is provided access to the requested snapshot. In response to determining that the requested snapshot is inactive, the requested snapshot is activated and the user is provided access to the requested snapshot.

Abstract: Provided herein are systems, methods and computer readable media for providing sales pipeline automation. An example method comprises calculating a forecasted demand, the forecasted demand comprising at least one or more virtual offers and a demanded quantity of at least a portion of the one or more virtual offers, identifying one or more merchants, wherein the one or more merchants are identified as able to supply at least a portion of the residual demand, assigning the one or more merchants to one or more sales resources in accordance with at least a calculated sales value of the one or more merchants.

Abstract: Monitoring an object to prevent an occurrence of an issue includes monitoring an object based on a number of parameters, categorizing messages of the object into categories while monitoring for a recurrence of a pattern of messages, detecting a potential issue with the object based on the recurrence of the pattern of messages, and alerting an operations manager agent of the potential issue to prevent an occurrence of the issue.

Abstract: Examples described relate to container images. An example method may include generating a mapping of respective unique identifiers of container images of a software container and respective metadata of the container images, validating the mapping against a rule to identify a unique identifier of a mapped container image that meets the rule, generating a target mapping that includes the unique identifier of the mapped container image that meets the rule and the action specified in the rule, and performing the action specified in the rule on the mapped container image corresponding to the unique identifier in the target mapping.

Abstract: Example methods, apparatus, systems and articles of manufacture (e.g., non-transitory physical storage media) to provide trust topology selection for distributed transaction processing in computing environments are disclosed herein. Example distributed transaction processing nodes disclosed herein include a distributed transaction application to process a transaction in a computing environment based on at least one of a centralized trust topology or a diffuse trust topology. Disclosed example distributed transaction processing nodes also include a trusted execution environment to protect first data associated with a centralized trust topology and to protect second data associated with a diffuse trust topology. Disclosed example distributed transaction processing nodes further include a trust topology selector to selectively configure the distributed transaction application to use the at least one of the centralized trust topology or the diffuse trust topology to process the transaction.

Abstract: A first network device detects a link down event associated with a second network device, where the link down event is detected by the first network device prior to being detected by a third network device, and the second network device is a designated network device of a network. The first network device starts a delay timer before processing the link down event, and detects an event that includes at least one of receipt, from the third network device, of a link state advertisement message based on the link down event, or an expiration of the delay timer. The first network device determines the first network device to be a new designated network device for the network based on detecting the event, and provides, to the third network device, information indicating that the first network device is the new designated network device for the network.

Abstract: A vehicle door includes an inner panel including an upper portion defining a window aperture, and a lower portion positioned opposite the upper portion in a vertical direction, and a support assembly coupled to the inner panel, the support assembly including a first torsion member extending along the upper portion of the inner panel in a lateral direction that is transverse to the vertical direction, the first torsion member defining holes extending through the first torsion member, a second torsion member extending along the upper portion of the inner panel toward the first torsion member, the second torsion member defining holes that are aligned with the holes of the first torsion member, and at least one fastener positioned in corresponding aligned holes of the first torsion member and the second torsion member, the at least one fastener coupling the first torsion member to the second torsion member.

Abstract: Display tiles comprising pixel elements on a first surface of a substrate connected by an electrode, a driver located opposite the first surface, and a connector wrapped around an edge surface of the substrate connecting the driver to the pixel elements. Displays comprised of display tiles and methods of manufacturing display tiles and displays are also disclosed.

Abstract: An aerosol delivery device is provided. The aerosol delivery device includes a power source, an aerosol production component, a sensor to produce measurements of atmospheric air pressure in an air flow path through at least one housing, and a switch coupled to and between the power source and the aerosol production component. The aerosol delivery device also includes processing circuitry coupled to the sensor and the switch. The processing circuitry determines a difference between the measurements of atmospheric air pressure from the sensor and a reference atmospheric air pressure. Only when the difference is at least a threshold difference, the processing circuitry outputs a signal to cause the switch to switchably connect and disconnect an output voltage from the power source to the aerosol production component to power the aerosol production component for an aerosol-production time period.

Abstract: An aerosol delivery device and an aerosol source member for use with an aerosol delivery device are provided. In various implementations, the aerosol source member comprises a substrate portion that includes a plurality of spaced susceptor bands. In one implementation, each susceptor band comprises a plurality of susceptor coils that are radially spaced around the longitudinal axis of the substrate portion, wherein each of the susceptor coils defines a longitudinal axis thereof, and wherein the longitudinal axis of each of the plurality of susceptor coils is substantially parallel to the longitudinal axis of the substrate portion. In another implementation, each susceptor band extends through the center of the substrate portion and across a diameter thereof, and wherein each susceptor band comprises a plurality of spaced susceptor particles.