Abstract: The present disclosure relates to a fully liquid immunogenic composition comprising a combination of antigens/immunogens. The immunogenic composition comprises optimum amount of antigens/immunogens to confer protection against a number of diseases. The composition exhibits improved immunogenicity and stability. A process for preparing the vaccine composition is also disclosed.

Abstract: The disclosure herein describes enabling authentication of a user's identity based on a user identification (ID) token. An enrollment request is received by an identity platform from a computing device of the user. The enrollment request includes face data and payment account data associated with a payment account of the user. A face identification template of the user is generated based on the face data. Based on verifying the user's identity using data in the enrollment request, an ID token is generated including the face identification template and the payment account data. The ID token is then provided to the computing device of the user, wherein the computing device is enabled to verify the user's identity based on comparison of the captured image data of the face of the user to the face identification template of the ID token during transactions associated with the computing device.

Abstract: Affibody polypeptides that specifically bind to B7-H3 are provided. Exemplary anti-B7-H3 affibodies are provided. The affibody polypeptides specifically recognize and bind to B7-H3 with high affinity.

Abstract: Compounds of Formula (I) are estrogen receptor alpha modulators, where the variables in Formula (I) are described in the disclosure. Such compounds, as well as pharmaceutically acceptable salts and compositions thereof, are useful for treating diseases or conditions that are estrogen receptor alpha dependent and/or estrogen receptor alpha mediated, including conditions characterized by excessive cellular proliferation, such as breast cancer.

Abstract: Administration of IHSs (Information Handling Systems) within a data center results gradual drift of the configuration parameters of the individual IHSs such that the IHSs may no longer be in compliance with data center policies, such as policies in support of security and disaster recovery procedures. Embodiments provide techniques for distributed determination of drift within a network of managed IHSs, in which each managed IHS is provided with baselines for the configuration parameters utilized by each managed IHS. Using the provided baselines, each managed IHS identifies discrepancies between its current configuration and the applicable baselines. Based on discrepancies reported by the managed IHSs, a management console evaluates drift within the network of managed IHSs and determines when to trigger remediation procedures in order to correct the drift.

Abstract: Systems involve a dividing unit configured to divide functionality in digital hardware portion through finite state machines (FSMs), protocol timers and PD message accelerator blocks for reducing code size such that their implementation combined with a low code-size firmware (FW) interacts, using a control unit operatively coupled to the dividing unit, with the hardware portion to provide updates in an USB-PD specification, wherein at least one of the FSMs configured to run at a predefined UI clock frequency to enable low active power to the system, a wake-up unit running at least on 4 times of UI clock frequency and detects data edge on configuration channel line to wake-up the entire system from sleep state, wherein a plurality of standard power saving mechanisms selected from clock gating and frequency reduction for clocks are implemented to enable low power corresponding to the system and bypass paths at each level of implementation.

Abstract: Systems and methods for detecting electrical connection and disconnection on an USB Type-A charging port like power adapters, power banks and car chargers having one or more USB Type-A charging port of an USB device. The system includes: a voltage source; a MOSFET SWITCH gate driver, in USB type-A connected state, that operatively couples MOSFET SWITCH with voltage source and VBUS supply of USB type-A port; charge pump; a current sense differential amplifier; and a control unit configured to: monitor VBUS current, and detect potential disconnected state of connected USB type-A port; and monitor VBUS voltage and compare VBUS voltage with predetermined voltage to sense external condition such that VBUS voltage drops because of load capacitance and load current. The control unit is further configured to, when the duty cycle has reached a minimum VBUS current, detect the USB type-A disconnection with a charge pump state.

Abstract: In one embodiment, a web content management system is coupled to remote resources via a framework that has one or more corresponding adapters which enable editing of content by invoking editors which are native to the respective remote resources. The system retrieves a content item from a remote resource and stores a copy of the content item in a local repository, while the original content item remains in the repository of the remote resource. A content item can be selected in in a local authoring tool, causing the system to examine the content item's metadata to identify the source repository and invoke the native editor of the corresponding remote resource, enabling editing of the content item using the native editor. The copy of the content item in the local repository can then be synchronized to the edited version of the content item in the remote resource.

Abstract: Systems involve a dividing unit configured to divide functionality in digital hardware portion through finite state machines (FSMs), protocol timers and PD message accelerator blocks for reducing code size such that their implementation combined with a low code-size firmware (FW) interacts, using a control unit operatively coupled to the dividing unit, with the hardware portion to provide updates in an USB-PD specification, wherein at least one of the FSMs configured to run at a predefined UI clock frequency to enable low active power to the system, a wake-up unit running at least on 4 times of UI clock frequency and detects data edge on configuration channel line to wake-up the entire system from sleep state, wherein a plurality of standard power saving mechanisms selected from clock gating and frequency reduction for clocks are implemented to enable low power corresponding to the system and bypass paths at each level of implementation.

Abstract: The present disclosure provides a system and method for soft start scheme to control inrush current for VCONN in USB-C interface. The system includes: a serial shift register having flip-flops and adapted to obtain clock with programmable clock divider, frequency of clock changes dynamically by programming programmable clock divider; a resistor DAC unit configured to increment voltage in step-wise manner; a pass gate switch comprising NMOS gate switch and a PMOS gate switch connected in parallel and operatively coupled to the resistor DAC unit and configured to control an input voltage to a VCONN charge pump, said input voltage being in incremental steps such that the VCONN charge pump pumps an output voltage; and a VCONN switch gate operatively coupled to the VCONN charge pump and configured to supply the output voltage in controlled, incremental steps, such that the output voltage is ramped slowly to control the inrush current.

Abstract: The present application relates to a method and apparatus including a sensor to detect a current location, a memory for storing a first set of Kalman filter parameters associated with a first environmental condition and a second set of Kalman filter parameters associated with a second environmental condition, a processor for performing an assisted driving algorithm according to the first set of Kalman filter parameters, for receiving the current location, for determining a second set of Kalman filter parameters in response to the current location, for performing the assisted driving algorithm according to the second set of Kalman filter parameters, and for generating a control signal in response to the assisted driving algorithm according to the second set of Kalman filter parameters, and a vehicle controller operative to control a vehicle in response to the control signal.

Abstract: Described embodiments provide systems and methods for detecting autonomous programs is provided. A device, intermediary to a plurality of clients and a plurality of servers, can receive a first request from a first client of the plurality of clients to a server of the plurality of servers via a connection between the device and the first client. The device can include, into a response from the server to the first client, a uniform resource locator (URL) comprising one or more randomly generated characters within a predetermined character space. The device can determine that the first client has an autonomous program responsive to receiving a second request from the first client using the URL. The device can terminate, responsive to the determination, the connection to the first client.

Abstract: A method of identifying IP-optical links in a network having a plurality of nodes, including: grouping network nodes into discovery groups; for each group filtering ports of the nodes in the discovery group; for each group producing class IDs for each filtered port using a machine learning model; for each group matching IP ports to optical ports from the filtered ports using the class IDs for each port to identify IP-optical links; and verifying identified IP-optical links.

Abstract: The present invention provides novel melon plants and plant parts, seed, fruit, and tissue culture therefrom. The invention also provides methods for producing a melon plant by crossing the melon plants of the invention with themselves or another melon plant. The invention also provides plants produced from such a crossing as well as plant parts, seed, fruit, and tissue culture therefrom.

Abstract: A monolithic integrated device may include a first device having a complementary metal-oxide-semiconductor (CMOS) substrate, and a second device arranged over the CMOS substrate. The second device may include a first conductive element, and a second conductive element arranged over the first conductive element. A via opening may extend through the first conductive element and the second conductive element of the second device to an interconnect of the CMOS substrate. A via contact may be arranged in the via opening to contact the first conductive element, the second conductive element, and the interconnect of the CMOS substrate. The via contact electrically connects the first conductive element and the second conductive element of the second device to the interconnect of the CMOS substrate.

Abstract: A network device may receive network traffic associated with a session, wherein the session is associated with a network. The network device may determine, from the network traffic, an application path that is associated with the session, wherein the application path is associated with a communication protocol and an application protocol. The network device may determine, based on policy information that is associated with the application path, whether the network traffic associated with the session is capable of being communicated via the network using the communication protocol and the application protocol. The network device may perform, based on whether the network traffic is determined to be capable of being communicated, an action associated with enabling or preventing communication of the network traffic.

Abstract: A method of manufacturing a graphene-baseddevice, comprising (i) providing a graphene assembly comprising one or more layers of graphene, a first photoresist layer disposed on the one or more layers of graphene, and an ultra-violet (UV) barrier layer disposed on the photoresist layer on an opposite side to the one or more layers of graphene; (ii) transferring the graphene assembly onto a substrate comprising at least one cavity so that the one or more layers of graphene traverse the at least one cavity; (iii) using photolithography to expose portions of the one or morelayers of graphene on opposite sides of the at least one cavity;(iv) forming conductive contacts over the exposed portions of graphene; (v) removing the UV barrier layer; and (vi) removing the first photoresist layer.

Abstract: Provided herein are improved processes for the preparation of a compound of Formula IX (AG-10). Also provided herein are pharmaceutically acceptable salts of Formula I and Formula Ib as well as crystalline types of Formula IX (AG-10). The processes described herein provide improved yields and efficiency, while the pharmaceutically acceptable salts and crystalline forms provide unexpected pharmacokinetic properties. Other features and aspects of the present disclosure will be apparent to a person of skill in the art upon reading the remainder of the specification.

Abstract: A system and method for facilitating reusability of distributed computing pipelines, initially, captures the distributed computing pipeline designed over a Graphical User Interface (GUI) of a first data processing environment associated with a stream analytics platform. Subsequent to the designing, the distributed computing pipeline may be stored in a repository. The distributed computing pipeline may be stored in a file with a predefined file format pertaining to the stream analytics platform. The system also maintains a repository of different versions of the distributed computing pipeline created by the first and second user. Upon storing the file, the file may be imported in a second data processing environment. After importing the file, the distributed computing pipeline may be populated over the GUI of the second data processing environment, thereby facilitating reusability of the distributed computing pipeline.

Abstract: The present disclosure provides immunomodulatory compositions comprising live Caulobacter crescentus (CC). Immunomodulatory compositions of the present disclosure are useful for modulating an immune response in an individual. The present disclosure thus provides methods of modulating an immune response in an individual, involving administering an immunomodulatory composition comprising live CC to the individual.