Abstract: According to embodiments, systems and methods for non-invasive blood pressure monitoring are disclosed. An exciter may induce perturbations in a subject, and a sensor or probe may be used to obtain a detected signal from the subject. The detected signal may then be used to measure one or more physiological parameters of the patient. For example if the perturbations are based on a known signal, any differences between the known signal and the input signal may be attributable to the patient's physiological parameters. A phase drift between the perturbation signal and the detected signal may be determined from a comparison of the scalograms of the exciter location and the sensor or probe location. From the scalogram comparison, more accurate and reliable physiological parameters may be determined.

Abstract: The present disclosure relates to systems and methods for analyzing and normalizing signals, such as PPG signals, for use in patent monitoring. The PPG signal may be detected using a continuous non-invasive blood pressure monitoring system and the normalized signals may be used to determine whether a recalibration of the system should be performed.

Abstract: The present disclosure relates to systems and methods for monitoring pain management using measurements of physiological parameters based on a PPG signal. A reference physiological parameter may be compared against a later measurement to identify a change in condition that may indicate a pain management problem.

Abstract: The present disclosure relates to systems and methods for monitoring pain management using measurements of physiological parameters based on a PPG signal. A reference physiological parameter may be compared against a later measurement to identify a change in condition that may indicate a pain management problem.

Abstract: According to some embodiments, systems and methods are provided for non-invasive continuous blood pressure determination. In some embodiments, a PPG signal is received and locations of pulses within the PPG signal are identified. An area within a particular pulse is measured. The area may be of just the upstroke, downstroke or the entire pulse. The area may be measured relative to a time-domain axis or a baseline of the pulse. The pulse may be split into multiple sections and the area of each section may be measured. The area of one portion of the pulse may correspond to systolic blood pressure while the area of another portion may correspond to diastolic blood pressure. Empirical data may be used to determine blood pressure from the measured area by applying calibration data measured by a suitable device.

Abstract: Systems and methods are provided for monitoring a correlation between heart rate and blood pressure in a patient. When a characteristic of the correlation exceeds a threshold, a patient status indicator signal is sent to a monitoring device. In some embodiments, the patient status indicator signal indicates a particular medical condition or alerts a care provider to a change in status. In some embodiments, the heart rate signal is used to improve a blood pressure estimate generated by a different signal. In some embodiments, the heart rate, blood pressure and correlation signals are used in a predictive mathematical model to estimate patient status or outcome.

Abstract: Systems and methods are provided for monitoring a correlation between heart rate and blood pressure in a patient. When a characteristic of the correlation exceeds a threshold, a patient status indicator signal is sent to a monitoring device. In some embodiments, the patient status indicator signal indicates a particular medical condition or alerts a care provider to a change in status. In some embodiments, the heart rate signal is used to improve a blood pressure estimate generated by a different signal. In some embodiments, the heart rate, blood pressure and correlation signals are used in a predictive mathematical model to estimate patient status or outcome.

Abstract: Systems and methods are provided for determining when to update a blood pressure measurement. The value of a physiological metric may be monitored and compared to a reference value. A patient monitoring system may compute a difference between a monitored metric and a reference value, and compare the difference to a threshold value to determine whether to update a blood pressure measurement. The threshold value may be constant or variable, and may depend on the monitored metric.

Abstract: Systems and methods are provided for storing event markers. The value of a monitored physiological metric may be monitored and compared to a reference value. A patient monitoring system may compute a difference between a monitored metric and a reference value, and compare the difference to a threshold value to determine whether a physiological event has occurred. Based on the determination, a patient monitoring system may store an event marker, trigger a response, update a metric value, or perform any other suitable function.

Abstract: Systems and methods are disclosed herein for calibrating the calculation of physiological parameters. Two or more calibration techniques may be used to determine a relationship between physiological measurements and a desired physiological parameter, such as a relationship between differential pulse transit time (DPTT) and blood pressure. Different calibration techniques may be used in a serial fashion, one after the other, or in a parallel fashion, with different weights accorded to each calibration technique. When physiological or other changes occur, the calibration data may be stored for later use and new calibration data may be generated.

Abstract: Techniques and structures are disclosed for using photoplethysmograph (PPG) and electrocardiographic (EKG)-based readings of a subject to determine one or more physiological characteristics of the subject. In an arrangement, a combined PPG-EKG sensor unit may be used to detect both PPG and EKG signals of the subject. The sensor unit may include a PPG sensor, an EKG sensor, and a support structure for connecting or fastening the sensor unit to the subject. The detected readings may be provided to an electronic monitor. In an arrangement, a PPG-EKG monitoring system, including the electronic monitor, may be used to determine the physiological parameters of the subject. The monitoring system may first determine an auxiliary parameter based at least in part on the EKG signal, and then compute the one or more physiological characteristics of the subject based at least in part on both the PPG signal and the auxiliary parameter.

Abstract: The present disclosure relates to systems and methods for analyzing and normalizing signals, such as PPG signals, for use in patent monitoring. The PPG signal may be detected using a continuous non-invasive blood pressure monitoring system and the normalized signals may be used to determine whether a recalibration of the system should be performed.

Abstract: Systems and methods are disclosed herein for continuous non-invasive blood pressure (CNIBP) monitoring. Multiple reference blood pressure values may be obtained using a calibration device. These multiple reference blood pressure values may be used as calibration points for determining a relationship between the blood pressure of a patient and photoplethysmograph (PPG) signals.

Abstract: The present disclosure provides a sensor with color-coded indications that various patient physiological parameters are being monitored, such as blood oxygen saturation, blood pressure, respiration rate, and respiration effort. The sensor may sense a physical characteristic used to monitor the physiological parameter, and a visible light emitter emits visible light of a first color that is color-coded to the physiological parameter, but is not used to sense the physical characteristic. The visible light emitter may emit visibly flashing light in response to the sensor sensing a threshold value of the physical characteristic. The sensor may include a second light emitter that may sense the physical characteristic, and may emit light of a second color that is color-coded to a first or second physiological parameter. In some embodiments, the first and second colors may visibly mix. The first and second visible light emitters may emit light independently, including visibly flashing light.

Abstract: The present disclosure relates to systems and methods for monitoring pain management using measurements of physiological parameters based on a PPG signal. A reference physiological parameter may be compared against a later measurement to identify a change in condition that may indicate a pain management problem.

Abstract: The present disclosure relates to systems and methods for monitoring pain management using measurements of physiological parameters based on a PPG signal. A reference physiological parameter may be compared against a later measurement to identify a change in condition that may indicate a pain management problem.

Abstract: The present disclosure relates to systems and methods for monitoring pain management using measurements of physiological parameters based on a PPG signal. A reference physiological parameter may be compared against a later measurement to identify a change in condition that may indicate a pain management problem.

Abstract: The present disclosure relates to systems and methods for monitoring pain management using measurements of physiological parameters based on a PPG signal. A reference physiological parameter may be compared against a later measurement to identify a change in condition that may indicate a pain management problem.

Abstract: Systems and methods are provided for monitoring a correlation between heart rate and blood pressure in a patient. When a characteristic of the correlation exceeds a threshold, a patient status indicator signal is sent to a monitoring device In some embodiments, the patient status indicator signal indicates a particular medical condition or alerts a care provider to a change in status. In some embodiments, the heart rate signal is used to improve a blood pressure estimate generated by a different signal. In some embodiments, the heart rate, blood pressure and correlation signals are used in a predictive mathematical model to estimate patient status or outcome.

Abstract: Systems and methods are disclosed herein for maintaining the calibration of non-invasive blood pressure monitoring devices. Phase components of pulse signals detected by the blood pressure monitoring device are compared to stored baseline phase component values. If the difference exceeds a threshold, the blood pressure monitoring device is recalibrated.