Abstract: A new approach is proposed that contemplates systems and methods to support distributed electronic payment processing based on a hierarchical payment graph. Specifically, a distributed electronic payment system comprising a plurality of distributed payment engines/processors. Upon receiving an electronic payment request from a client device, each distributed payment engine of the distributed electronic payment system is configured to handle one stage of the electronic payment processing lifecycle by traversing states and edges in a portion of the hierarchical payment graph assigned to the distributed payment engine.

Abstract: A new approach is proposed that contemplates systems and methods to support distributed electronic payment processing based on a hierarchical payment graph. Specifically, a distributed electronic payment system comprising a plurality of distributed payment engines/processors. Upon receiving an electronic payment request from a client device, each distributed payment engine of the distributed electronic payment system is configured to handle one stage of the electronic payment processing lifecycle by traversing states and edges in a portion of the hierarchical payment graph assigned to the distributed payment engine.

Abstract: Disclosed herein, inter alia, are compounds and methods for inhibiting Caspase 6 and the treatment of diseases, pharmaceutical composition including a compound as described herein and a pharmaceutically acceptable excipient and methods of inhibiting human Caspase 6 protein activity, the method including: contacting the human Caspase 6 protein with a compound as described herein.

Abstract: Various embodiments of the present disclosure are directed to compounds having Formula (I), Formula (IA), Formula (IB), Formula (IC), Formula (ID), Formula (IE), and/or pharmaceutically acceptable salts thereof. The compounds can be suitable for inhibiting lipoxygenases, and/or treating associated diseases, such as Alzheimer's disease. In some embodiments, the compounds may be administered to a patient as part of a pharmaceutical formulation.

Abstract: Various embodiments of the present disclosure are directed to compounds having Formula I, Formula II, Formula IIA, Formula III, Formula IIIA, Formula IIIB, and/or pharmaceutically acceptable salts thereof. The compounds can be suitable for inhibiting lipoxygenases and/or treating associated diseases. In some embodiments, subject compounds are used to prepare a composition that is effective in treating neurodegenerative diseases.

Abstract: A approach is proposed to support typed payment graph-based electronic payment processing. First, schemas for one or more typed payment graphs used for a plurality types of electronic payment processing are defined declaratively. Upon receiving an electronic payment request from a client, a payment processing engine retrieves a schema of a typed payment graph corresponding to the request and processes the electronic payment by traversing states and edges in an instance created from the schema of the typed payment graph. The electronic payment only transitions from one state to another if a valid edge exists between them and a precondition on the edge is met by the processing results of the electronic payment at the state. While processing the electronic payment, the payment processing engine automatically generates an audit trail for the electronic payment based on its states and transitions for real time recovery and/or analysis.

Abstract: The present disclosure relates to methods of diagnosing acute rejection of a cardiac allograft in a subject using genomic expression profiling, proteomic expression profiling, or both on panels of nucleic acid markers and proteomic markers.

Abstract: The present disclosure relates to systems, non-transitory computer-readable media, and methods of a process management system that improves memory management and resource utilization on host devices that utilize a pre-fork worker process model (e.g., uWSGI). For example, the process management system can utilize the memory consumption of the host device to determine how many worker processes to terminate as well as which worker processes to terminate. In addition, the process management system can utilize adaptive respawning to determine when to respawn each of the terminated worker processes.

Abstract: Provided herein are compounds useful for the treatment of various proliferative diseases. These compounds, as well as pharmaceutically acceptable salts thereof may be formulated in pharmaceutical compositions, and may be used in methods of treatment and/or prophylaxis of proliferative diseases, including cancer, and more specifically, pancreatic cancer.

Abstract: A new approach is proposed that contemplates systems and methods to support distributed electronic payment processing based on a hierarchical payment graph. Specifically, a distributed electronic payment system comprising a plurality of distributed payment engines/processors. Upon receiving an electronic payment request from a client device, each distributed payment engine of the distributed electronic payment system is configured to handle one stage of the electronic payment processing lifecycle by traversing states and edges in a portion of the hierarchical payment graph assigned to the distributed payment engine.

Abstract: A system for tracking the performance of a medical device including a memory, a display device; a medical device connector connected to the medical device, a processor operable to receive operational data from the medical device connector, determine a plurality of device metadata from the operational data, receive a plurality of environmental data from the medical device, determine a plurality of performance criteria based on the environmental data from the medical device, and display the performance criteria on the display device.

Abstract: A cello stand system for holding a cello that includes a base; a first and second arm, where each arm comprises at least one cello engagement region on an inner-side of the arm; where each arm is attached in an upright orientation along the length of the base; and where the inner-sides of the first and second arms and a top surface of the base define a cello holding cavity. The cello stand system functions to engage with a cello across a rib of the upper or lower bout to hold a cello on its side in a horizontal position.

Abstract: A approach is proposed to support typed payment graph-based electronic payment processing. First, schemas for one or more typed payment graphs used for a plurality types of electronic payment processing are defined declaratively. Upon receiving an electronic payment request from a client, a payment processing engine retrieves a schema of a typed payment graph corresponding to the request and processes the electronic payment by traversing states and edges in an instance created from the schema of the typed payment graph. The electronic payment only transitions from one state to another if a valid edge exists between them and a precondition on the edge is met by the processing results of the electronic payment at the state. While processing the electronic payment, the payment processing engine automatically generates an audit trail for the electronic payment based on its states and transitions for real time recovery and/or analysis.

Abstract: The present disclosure relates to methods of diagnosing acute rejection of a cardiac allograft in a subject using genomic expression profiling, proteomic expression profiling, or both on panels of nucleic acid markers and proteomic markers.

Abstract: A cello stand system for holding a cello that includes a base; a first and second arm, where each arm comprises at least one cello engagement region on an inner-side of the arm; where each arm is attached in an upright orientation along the length of the base; and where the inner-sides of the first and second arms and a top surface of the base define a cello holding cavity. The cello stand system functions to engage with a cello across a rib of the upper or lower bout to hold a cello on its side in a horizontal position.

Abstract: Provided are substituted quinuclidine compounds, pharmaceutical compositions comprising such compounds, and methods of modulating ?7 nicotinic acetylcholine receptors and treating neurological disorders using such compounds.

Abstract: Provided are substituted quinuclidine compounds, pharmaceutical compositions comprising such compounds, and methods of modulating ?7 nicotinic acetylcholine receptors and treating neurological disorders using such compounds.

Abstract: Efficient architecture for a secure access enforcement proxy is described. The proxy interfaces with multiple subsystems and multiple shared resources. The proxy identifies an original transaction command being sent from one of the subsystems to one of the shared resources, identifies a policy corresponding to the subsystem, performs an action pertaining to the original transaction command based on the policy, and sends a response to the subsystem based on the action.