Abstract: The present invention is directed to a novel 2-substituted benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

Abstract: The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

Abstract: Provided are compounds, pharmaceutical compositions and methods of treatment or prophylaxis of an inflammatory condition, in particular asthma. The compounds are of the general Formula I, or a pharmaceutically acceptable salt, ester, prodrug or derivative thereof: wherein: X and Y are independently selected from —CH2— or —CH2—CH2—; Z is selected from S(O)m or Se(O)m and m is 0, 1 or 2; R1 is optionally substituted heteroaryl or heterocyclic; R2 is selected from the group consisting of hydrogen, C1-C6 straight alkyl, and C1-C6 branched alkyl, wherein all may be optionally substituted; and R3 and R4 are alkyl.

Abstract: The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

Abstract: The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

Abstract: There is provided an insert ear bud earphone with variable noise isolation. The earphone includes a housing with a serpentine channel which is able to contain at least one transducer in a main body of the housing; and a cushion which contacts a user's ear canal wall, the cushion being mounted on the serpentine channel. There is preferably at least one opening in either the housing or the cushion which causes leakage and allows ambient noise to enter the user's ear canal. There is also provided a cushion for an insert ear bud earphone. Finally, there is provided a method to enable variable noise isolation in an insert ear bud earphone comprising an inclusion of at least one opening in either a housing of the earphone or a cushion mounted on the earphone which causes leakage and allows ambient noise to enter a user's ear canal.

Abstract: The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

Abstract: Disclosed herein is a system for use in a tank containing a contaminative fluid. The system includes an electrically conductive resistive material in fluid communication with the contents of the tank, a controller configured to periodically generate a control signal, and a variable power supply coupled to the electrically conductive material to provide a current within a normal operating range and to supply current at an elevated level in response to a control signal, wherein the elevated level is selected to heat the electrically conductive material to a temperature sufficient to remove contamination building thereon.

Abstract: The current invention provides compounds having a structure according to Formulae 1, 2, 3, and 4: wherein the A-ring, B-ring, C-ring, m, n, R25, R50, and R51 are as described in the specification. The invention also provides pharmaceutical compositions comprising compounds of Formulae 1, 2, 3, and 4, as well as methods of treating cognitive disorders, such as Alzheimer's disease. The invention further provides intermediates useful in preparing the compounds of Formulae 1, 2, 3, and 4.

Abstract: A method and network device for re-ordering segments of a segmented data stream. The method includes receiving at least two segments of a segmented data stream. A descriptor for each of the at least two segments is obtained, and the at least two segments are re-ordered to generate re-ordered segments, where the re-ordered segments are in an original order. A set of re-ordered segments are processed to obtain at least one data packet, where at least one descriptor is utilized in the processing of the set of re-ordered segments.

Abstract: A manufacturing process and apparatus therefore are provided for processing an electronic device comprising oxidizable material during processing. The electronic device is located inside a chamber and is heated a processing temperature with a heater. A reductive atmosphere is created in the chamber by supplying a gas comprising glycolic acid vapor while processing the electronic device at the processing temperature.

Abstract: Provided are compounds, pharmaceutical compositions and methods of treatment or prophylaxis of an inflammatory condition, in particular asthma. The compounds are of the general Formula I, or a pharmaceutically acceptable salt, ester, prodrug or derivative thereof: wherein: X and Y are independently selected from —CH2— or —CH2—CH2—; Z is selected from S(O)m or Se(O)m and m is 0, 1 or 2; R1 is optionally substituted heteroaryl or heterocyclic; R2 is selected from the group consisting of hydrogen, C1-C6 straight alkyl, and C1-C6 branched alkyl, wherein all may be optionally substituted; and R3 and R4 are alkyl.

Abstract: The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

Abstract: The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

Abstract: The present invention discloses the use of generalized queries, referred to as query templates, obtained by generalizing individual user queries, as the semantic basis for low overhead, high benefit directory caches for handling declarative queries. Caching effectiveness can be improved by maintaining a set of generalizations of queries and admitting such generalizations into the cache when their estimated benefits are sufficiently high. In a preferred embodiment of the invention, the admission of query templates into the cache can be done in what is referred to by the inventors as a “revolutionary” fashion—followed by stable periods where cache admission and replacement can be done incrementally in an evolutionary fashion. The present invention can lead to considerably higher hit rates and lower server-side execution and communication costs than conventional caching of directory queries—while keeping the clientside computational overheads comparable to query caching.

Abstract: Provided are compounds, pharmaceutical compositions and methods of treatment or prophylaxis of an inflammatory condition, in particular asthma. The compounds are of the general Formula I, or a pharmaceutically acceptable salt, ester, prodrug or derivative thereof: wherein Y, Z and R1-R12 are defined herein.

Abstract: The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

Abstract: A manufacturing process and apparatus therefore are provided for processing an electronic device comprising oxidizable material during processing. The electronic device is located inside a chamber and is heated a processing temperature with a heater. A reductive atmosphere is created in the chamber by supplying a gas comprising glycolic acid vapor while processing the electronic device at the processing temperature.

Abstract: The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

Abstract: Methods, software and systems for handling parity errors in flow control channels are presented. A network processor is provided having a flow control message First In First Out (FIFO) buffer and wherein the FIFO buffer includes a parity field. The network processor is included as either or both of an Ingress network processor and an Egress network processor and is used within a CSIX system or an NPSI NPE system.