Abstract: The invention relates to mutant G-protein coupled receptors with increased conformational stability, and methods of use thereof. In some aspects, polynucleotides encoding the mutant G-protein coupled receptors are provided. In some aspects, host cells comprising the polynucleotides are provided. In some aspects, the invention relates to crystallized forms of the mutant G-protein coupled receptors, and methods of preparing the same.

Abstract: A control system for a satellite comprises a power source and control system, a propulsion system having individually selectable solid fuel motors, a communication interface and an attitude determination and control system (ADCS). The ADCS receives power from the power source and control system and further receives desired orbital or positional instructions via the communication interface. Based on the desired orbital or position instructions, the ADCS generates and provides commands to the propulsion system. In turn, the propulsion system selects and fires one or more motors of the individually selectable solid fuel motors responsive to the commands received from the ADCS. A satellite may comprise the disclosed satellite control system as well as attitude control components and/or sensor components operatively connected to the satellite control system.

Abstract: A command interpreter is in communication with a wireless controller. The command interpreter is configured to identify a reference location of the wireless controller, identify a second location of the wireless controller, and determine, based on the reference location and the second location, a sequence of instrument commands configured to adjust positioning of the instrument device.

Abstract: An ultrasound system includes a display, an actuator, a user interface, and a processing circuit. The actuator is configured to control at least one of a position or an orientation of the display. The user interface is configured to receive a user input. The processing circuit is configured to cause the actuator to adjust the at least one of the position or orientation of the display based on the user input.

Abstract: A method for displaying status information related to a portable device includes detecting a portion of a user in a detection zone using a proximity sensor, determining, using a control circuit, that the portable device is in a powered off or power saving state, acquiring, using the control circuit, information about the portable device while the portable device remains in the powered off or power saving state, and displaying, using a system status indicator controlled by the control circuit, a representation of the information about the portable device. The detection zone is defined in relation to a handle of the portable device.

Abstract: A device may operate a guide wire and be operable by a single operator digit. The device may include an insertion control device for advancing the guide wire in a forward and in a reverse direction and along a longitudinal axis of the guide wire; and a rotary device for rolling a guide wire about the longitudinal axis. A robotic instrument driver may be operatively coupled to the device and configured to control axial movement of the guide wire along the longitudinal axis according to input received from the insertion control device and to control rotational movement of the guide wire according to input received from the rotary device.

Abstract: A method for displaying status information related to a portable device includes detecting a portion of a user in a detection zone using a proximity sensor, determining, using a control circuit, that the portable device is in a powered off or power saving state, acquiring, using the control circuit, information about the portable device while the portable device remains in the powered off or power saving state, and displaying, using a system status indicator controlled by the control circuit, a representation of the information about the portable device. The detection zone is defined in relation to a handle of the portable device.

Abstract: An input device includes a plurality of orientation blocks each representing a portion of a catheter assembly and a controller configured to determine an orientation of the plurality of orientation blocks relative to one another. The controller is further configured to output a control signal that causes a tip of a catheter assembly to adopt the orientation determined by the controller. A system includes an actuator configured to manipulate a position and orientation of the catheter assembly. The controller of the input device is configured to output a control signal to the actuator to make a tip of a catheter assembly adopt the orientation determined by the controller. The input device can be virtually represented on a computing device.

Abstract: A command interpreter is in communication with a wireless controller. The command interpreter is configured to identify a reference location of the wireless controller, identify a second location of the wireless controller, and determine, based on the reference location and the second location, a sequence of instrument commands configured to adjust positioning of the instrument device.

Abstract: A device may operate a guide wire and be operable by a single operator digit. The device may include an insertion control device for advancing the guide wire in a forward and in a reverse direction and along a longitudinal axis of the guide wire; and a rotary device for rolling a guide wire about the longitudinal axis. A robotic instrument driver may be operatively coupled to the device and configured to control axial movement of the guide wire along the longitudinal axis according to input received from the insertion control device and to control rotational movement of the guide wire according to input received from the rotary device.

Abstract: A portable ultrasound cart includes a support structure configured to releasably secure a portable ultrasound device. The support structure includes a wall and a planar surface which define a recess structured to receive a portion of the portable ultrasound device, a first male engagement feature positioned to engage with a first female engagement feature of the portable ultrasound device and a second male engagement feature positioned to engage with a second female engagement feature of the portable ultrasound device. The portable ultrasound cart also includes a tilt system positioned to adjust a tilt angle of the support structure relative to a remainder of the portable ultrasound cart, and a release lever linked to the second male engagement feature such that when the release lever is actuated, the second male engagement feature of the portable ultrasound cart disengages from the second female engagement feature of the portable ultrasound device.

Abstract: An apparatus for locking a transducer connector to a transducer interface of an ultrasound system includes a sensor configured to acquire data regarding a position of the transducer connector relative to the transducer interface, a locking system configured to facilitate locking of the transducer connector to the transducer interface, and a processing circuit communicably coupled to the sensor and the locking system. The processing circuit configured to interpret the data acquire by the sensor and provide a lock command to the locking system to lock the transducer connector to the transducer interface based on the data indicating the transducer connector is engaged with the transducer interface.

Abstract: One exemplary user interface for a medical robotics system may include a control panel and one or more sliders that may be slidably carried by the control panel to actuate one or more motors for moving a surgical instrument of the medical robotics system. The sliders may be configured to actuate the motors to move the surgical instrument along a respective one of a plurality of degrees of freedom.

Abstract: A command interpreter is in communication with a wireless controller. The command interpreter is configured to identify a reference location of the wireless controller, identify a second location of the wireless controller, and determine, based on the reference location and the second location, a sequence of instrument commands configured to adjust positioning of the instrument device.

Abstract: An ultrasound system is disclosed. The ultrasound system includes an ultrasound device. The ultrasound device includes a housing, a control panel coupled to the housing, and a receiver assembly coupled to the housing, wherein the receiver assembly includes a first contact surface. The ultrasound system further includes a transducer assembly having an ultrasound probe and a cartridge, wherein the cartridge includes a second contact surface. The cartridge is configured to be removably received in a slot of the receiver assembly such that the cartridge is movable between a removed position, in which the transducer assembly is not connected to the ultrasound device, and an engaged position, in which the cartridge is positioned in the slot and the first contact surface is electrically coupled to the second contact surface.