Patents by Inventor Richard A. Nelson

Richard A. Nelson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process device with light change triggered display
    Publication number: 20120293015
    Abstract: A field device comprises a transducer, a photodetector, a display, and a display controller. The transducer controls or monitors process variable, and the display shows information relating to the process variable. The photodetector detects a light level. The display controller is capable of switching the display on and off in response to changes in the light level detected by the photodetector.
    Type: Application
    Filed: May 16, 2011
    Publication date: November 22, 2012
    Applicant: Rosemount Inc.
    Inventors: James Johnson, Richard Nelson
  • ISOTHERMAL DNA AMPLIFICATION
    Publication number: 20120196330
    Abstract: Provided herein are nucleic acid synthesis methods and agents that employ an endonuclease for example, endonuclease V, to introduce a nick into a target DNA including one or more inosine, and uses a DNA polymerase to generate amplicons of the target DNA.
    Type: Application
    Filed: December 20, 2011
    Publication date: August 2, 2012
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: John Richard Nelson, Robert Scott Duthie, Carl Williams Fuller, Gregory Andrew Grossmann, Anuradha Sekher
  • Utility vehicle having modular components
    Patent number: 8205910
    Abstract: Multiple embodiments are disclosed which display modularity for accomplishing multiple modes of operation for a utility vehicle. The utility vehicle (100) may include a rear cargo platform (450), a plurality of connection points (460) disposed in matrix and adapted to couple an item to the rear cargo platform, and three or more couplings (490) for adding a subsection (470) in a non-pivotable manner or pivotably coupling the rear cargo platform. The vehicle may be a four-wheeled vehicle that coverts to a six-wheeled vehicle by the addition of the subsection. The utility vehicle may include a subsection cargo platform which may be coupled to the rear cargo platform and may pivot rearward. The utility vehicle may include couplings for adding a second subsection.
    Type: Grant
    Filed: March 17, 2008
    Date of Patent: June 26, 2012
    Assignee: Polaris Industries Inc.
    Inventors: Joshua J. Leonard, Richard Raymond Maki, Eric Bjerketvedt, Michael D. Schneider, Bradley Robert Morisch, Brian D. Krosschell, Lionel Hoff, James Bergman, Doug Moman, Mitchell D. Johnson, Larry Holter, Richard Nelson
  • METHOD FOR ELECTROELUTING GENETIC MATERIAL FROM DRIED SAMPLES
    Publication number: 20120152743
    Abstract: In accordance with the present disclosure, a method for extracting genetic material from a biological sample stored on a solid medium is provided. The method includes obtaining the solid medium, wherein the biological sample is applied on the solid medium, and the solid medium includes chemicals that lysed the biological sample and preserved the genetic material. The method also includes electroeluting the genetic material directly from the solid medium to a subsequent medium.
    Type: Application
    Filed: December 17, 2010
    Publication date: June 21, 2012
    Applicant: General Electric Company
    Inventors: Erin Jean Finehout, John Richard Nelson, Patrick McCoy Spooner
  • Isothermal DNA amplification
    Patent number: 8202972
    Abstract: Provided herein are nucleic acid synthesis methods and agents that employ an endonuclease for example, endonuclease V, to introduce a nick into a target DNA including one or more inosine, and uses a DNA polymerase to generate amplicons of the target DNA.
    Type: Grant
    Filed: January 10, 2007
    Date of Patent: June 19, 2012
    Assignee: General Electric Company
    Inventors: John Richard Nelson, Robert Scott Duthie, Carl Williams Fuller, Gregory Andrew Grossmann, Anuradha Sekher
  • COMPOSITION, DEVICE AND ASSOCIATED METHOD
    Publication number: 20120122735
    Abstract: A composition includes a first probe, a first initiator component bonded to the first probe, a second probe, and a second initiator component bonded to the second probe. The first probe and the second probe are capable of binding to a single analyte, and the first initiator component and the second initiator component are capable of forming an initiator when present in proximity to each other and when the first probe and the second probe are bonded to the analyte. An associated kit, device, and method are provided.
    Type: Application
    Filed: March 1, 2007
    Publication date: May 17, 2012
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: John Richard Nelson, Bahram Moasser, Anup Sood, Gregory Andrew Grossmann, Su Lu, Zhida Pan, Liangliang Qiang, John Yupeng Gui, Wei Cai, Zhixin Zheng
  • COMPOSITION, DEVICE AND ASSOCIATED METHOD
    Publication number: 20120122733
    Abstract: The composition includes a first probe and a first initiator bonded to the first probe. The composition further includes a second probe and a second initiator bonded to the second probe. The first probe and the second probe are capable of binding to a single analyte. An associated kit, device, and method are provided.
    Type: Application
    Filed: March 1, 2007
    Publication date: May 17, 2012
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Zhida Pan, Su Lu, Liangliang Qiang, John Yupeng Gui, John Richard Nelson, Bahram Moasser, Anup Sood, Gregory Andrew Grossmann, Wei Cai, Zhixin Zheng
  • COMPOSITION, DEVICE AND ASSOCIATED METHOD
    Publication number: 20120122734
    Abstract: A composition includes a first probe and a first initiator bonded to the first probe. The first probe is capable of binding to an analyte and the first initiator is capable of initiating a controlled polymerization reaction. An associated kit, device, and method are provided.
    Type: Application
    Filed: March 1, 2007
    Publication date: May 17, 2012
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Su Lu, John Yupeng Gui, Bahram Moasser, Wei Cai, Zhixin Zheng, John Richard Nelson
  • METHOD AND KITS FOR REPAIRING NUCLEIC ACID SEQUENCES
    Publication number: 20120107806
    Abstract: Methods and kits for DNA repair are provided. The methods and kits described herein repair multiple types of DNA damage. The kit may include a plurality of enzymes to repair a greater variety of lesions than any single enzyme is capable of repairing. Repair of damaged DNA may include releasing damaged bases from the DNA strand, nicking the DNA at the damaged sites, translating the nicks via 5?-3? exonuclease activity, and sealing the nicks. The enzymes employed in the repair process may then be heat-inactivated, thereby obviating a purification process. The repaired DNA may then be analyzed using a variety of DNA analysis methods.
    Type: Application
    Filed: January 5, 2012
    Publication date: May 3, 2012
    Applicant: General Electric Company
    Inventors: John Richard Nelson, Wei Gao
  • Vehicle with space utilization
    Patent number: 8167072
    Abstract: A utility vehicle with space utilization features is disclosed. The space utilization features provide storage and access to components.
    Type: Grant
    Filed: March 17, 2008
    Date of Patent: May 1, 2012
    Assignee: Polaris Industries Inc.
    Inventors: Joshua J. Leonard, Richard Raymond Maki, Eric Bjerketvedt, Michael D. Schneider, Bradley Robert Morisch, Brian D. Krosschell, Louis J. Brady, James Bergman, Larry Holter, Richard Nelson, Lionel Hoff, Doug Moman, Mitchell D. Johnson
  • Vehicle
    Patent number: 8132827
    Abstract: A utility vehicle with ergonomic, safety, and maintenance features is disclosed. The ergonomic, safety, and maintenance features enhance the utility of the vehicle.
    Type: Grant
    Filed: September 3, 2010
    Date of Patent: March 13, 2012
    Assignee: Polaris Industries Inc.
    Inventors: James Bergman, Larry Holter, Richard Nelson, Lionel Hoff, Doug Moman, Joshua J. Leonard, Mitchell D. Johnson, Richard Raymond Maki, Eric Bjerkelvedt, Bradley Robert Morisch, Brian D. Krosschell, Louis J. Brady, Michael D. Schneider
  • Method of stimulating the motility of the gastrointestinal system using ipamorelin
    Publication number: 20120010157
    Abstract: The present invention provides a method of stimulating the motility of the gastrointestinal system in a subject in need thereof, wherein the subject suffers from maladies (i.e., disorders, diseases, conditions, or drug- or surgery-induced dysfunction) of the gastrointestinal system, by administering to the subject a ghrelin mimetic, or pharmaceutically acceptable salt thereof. The invention also provides a method of treating a gastrointestinal malady by co-administering a ghrelin mimetic with a laxative, a H2 receptor antagonist, a serotonin receptor agonist, pure or mixed, an antacid, an opioid antagonist, a proton pump inhibitor, a motilin receptor agonist, dopamine antagonist, a cholinergic agonist, a cholinesterase inhibitor, somatostatin, octreotide, or any combination thereof.
    Type: Application
    Filed: September 16, 2011
    Publication date: January 12, 2012
    Applicant: HELSINN THERAPEUTICS (U.S.), INC.
    Inventors: William J. Polvino, Richard Nelson, William R. Mann
  • METHODS AND KITS FOR REDUCING NON-SPECIFIC NUCLEIC ACID AMPLIFICATION
    Publication number: 20110287510
    Abstract: Methods and kits for efficient amplification of nucleic acids are provided. The methods comprise in-vitro amplification of a nucleic acid template employing partially constrained primers having terminal mismatch primer-dimer structure. The methods also comprise in-vitro amplification of a nucleic acid template employing partially constrained primers having nucleotide analogues. The methods enhance efficiency of nucleic acid amplification reaction by reducing non-specific amplification reactions.
    Type: Application
    Filed: July 15, 2011
    Publication date: November 24, 2011
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: John Richard Nelson, Robert Scott Duthie, Sonali Jagdish Shah, Clifford Leslie Smith
  • NUCLEIC ACID DELIVERY VEHICLE AND USES THEREOF
    Publication number: 20110274706
    Abstract: A nucleic acid-delivery vehicle for delivering nucleic acids to target cells is provided. The nucleic acid-delivery vehicle comprises a plurality of nanoparticles; and a plurality of nucleic acids. The nanoparticles further comprises one or more signal peptides attached to the nanoparticles. The nanoparticles and the nucleic acids are agglomerated to form a nucleic acid-granulation particle having a dimension of at least 20 nm. Methods of making the nucleic acid-delivery vehicle and kits comprising nucleic acid-delivery vehicle are also provided.
    Type: Application
    Filed: May 4, 2010
    Publication date: November 10, 2011
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: John Richard Nelson, Timothy James Yosenick
  • NUCLEIC ACID DELIVERY VEHICLE AND USES THEREOF
    Publication number: 20110274757
    Abstract: A nucleic acid-delivery vehicle for delivering nucleic acids to target cells is provided. The nucleic acid-delivery vehicle comprises a plurality of nanoparticles; and a plurality of nucleic acids. The nanoparticles and the nucleic acids are agglomerated to form a nucleic acid-granulation particle having a dimension of at least 5 nm. Methods of making the nucleic acid-delivery vehicle and kits comprising nucleic acid-delivery vehicle are also provided.
    Type: Application
    Filed: May 4, 2010
    Publication date: November 10, 2011
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: John Richard Nelson, Timothy James Yosenick
  • Method of stimulating the motility of the gastrointestinal system using ipamorelin
    Patent number: 8039456
    Abstract: The present invention provides a method of stimulating the motility of the gastrointestinal system in a subject in need thereof, wherein the subject suffers from maladies (i.e., disorders, diseases, conditions, or drug- or surgery-induced dysfunction) of the gastrointestinal system, by administering to the subject a ghrelin mimetic, or pharmaceutically acceptable salt thereof. The invention also provides a method of treating a gastrointestinal malady by co-administering a ghrelin mimetic with a laxative, a H2 receptor antagonist, a serotonin receptor agonist, pure or mixed, an antacid, an opioid antagonist, a proton pump inhibitor, a motilin receptor agonist, dopamine antagonist, a cholinergic agonist, a cholinesterase inhibitor, somatostatin, octreotide, or any combination thereof.
    Type: Grant
    Filed: November 26, 2008
    Date of Patent: October 18, 2011
    Assignee: Helsinn Therapeutics (U.S.), Inc.
    Inventors: William J. Polvino, Richard Nelson, William R. Mann
  • DNA VACCINES, USES FOR UNPROCESSED ROLLING CIRCLE AMPLIFICATION PRODUCT AND METHODS FOR MAKING THE SAME
    Publication number: 20110206728
    Abstract: A method of eliciting an immune response in an organism comprising: providing an unprocessed rolling circle amplification (RCA) product; and administering an effective amount of the unprocessed RCA product to the organism to elicit the immune response, wherein the unprocessed RCA product is prepared from a circular nucleic acid template comprising at least one promoter sequence, and at least one target sequence. A vaccine comprising unprocessed RCA product is also provided and methods for making the same.
    Type: Application
    Filed: March 31, 2011
    Publication date: August 25, 2011
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: John Richard Nelson, Nichole Lea Wood, Brian Michael Davis, Andrew Soliz Torres
  • ISOTHERMAL AMPLIFICATION OF NUCLEIC ACID USING PRIMERS COMPRISING A RANDOMIZED SEQUENCE AND SPECIFIC PRIMERS AND USES THEREOF
    Publication number: 20110195457
    Abstract: Methods and kits for amplifying a nucleic acid under isothermal conditions to form an amplified nucleic acid sequence are provided. The methods and kits comprises providing a nucleic acid template, a DNA polymerase, deoxyribonucleoside triphosphates, a primer comprising a randomized sequence, and a specific primer, and amplifying the nucleic acid template.
    Type: Application
    Filed: February 9, 2010
    Publication date: August 11, 2011
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: John Richard Nelson, Wei Gao, Ming Zhao
  • Methods and kits for reducing non-specific nucleic acid amplification
    Patent number: 7993839
    Abstract: Methods and kits for efficient amplification of nucleic acids are provided. The methods comprise in-vitro amplification of a nucleic acid template employing partially constrained primers having terminal mismatch primer-dimer structure. The methods also comprise in-vitro amplification of a nucleic acid template employing partially constrained primers having nucleotide analogues. The methods enhance efficiency of nucleic acid amplification reaction by reducing non-specific amplification reactions.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: August 9, 2011
    Assignee: General Electric Company
    Inventors: John Richard Nelson, Robert Scott Duthie, Sonali Jagdish Shah, Clifford Leslie Smith
  • Circuit board via arrangement for differential signal connector
    Patent number: RE43330
    Abstract: Stacked receptacles in a connector that each provide side-by-side differential signal contacts, are attached to a circuit board without additional width to accommodate multiple layers of differential signals by using connector wafer inserts that rotate the side-by-side positioned differential signal contacts to front-to-back contacts, the circuit board including a substrate having a plurality of openings to make electrical contact with conductive terminal tail portion inserted therein, the openings being divided into first and second groups of openings, the first group of openings receiving differential signal terminal tails therein and the second group of openings receiving ground terminal tail therein, when a connector is mounted to said circuit board.
    Type: Grant
    Filed: December 23, 2010
    Date of Patent: May 1, 2012
    Assignee: Molex Incorporated
    Inventors: Hazelton P. Avery, Patrick R. Casher, Richard A. Nelson, Kent E. Regnier