Abstract: A bed (10) includes a base (12) and a frame assembly (14). A head end support assembly (16) and a foot end support assembly (18) are coupled between the base (12) and the frame assembly (14). The frame assembly (14) includes first and second side frame members (80, 82) located above the base (12). The bed (10) also includes a plurality of latch mechanisms (160) coupled to the first and second side frame members (80, 82), and a patient support surface (162) configured to be coupled to the first and second side frame members (80, 82) by the plurality of latch mechanisms (160). A rotational drive mechanism (130) is coupled to the foot end support assembly (18) to rotate the frame assembly (14) about its longitudinal axis to a prone position. A proning surface (250) is coupled to the frame assembly (14) to support a patient in the prone position.

Abstract: A method for treating a subject afflicted with a cardiac disorder, in vivo, comprising (i) producing a solution comprising media conditioned from the culture of cells, in vitro, and (ii) administering the solution of step (i) to the subject, thereby treating the cardiac disorder in the subject. Methods for determining whether an agent stimulates or inhibits myocyte proliferation.

Abstract: A system and method for distributing digital media assets to a plurality of users. A portal is provided comprising at least one server computer. The portal executes a media library database server application that manages access a master library of media 5 assets that can be accessed by users via one or more communication networks. A plurality of media player devices communicate with the portal to access media assets for use. Each media player device may comprise a processor that executes a database client application that manages media assets licensed for use by a user.

Abstract: A method for treating a subject afflicted with a cardiac disorder, in vivo, comprises (i) inducing differentiation of a progenitor cell, in vitro, to a cardiogenic cell; and (ii) administering a therapeutically effective amount of the cardiogenic cell of step (i) to the subject, thereby treating the cardiac disorder in the subject. This invention further provides related articles of manufacture and methods.

Abstract: An oral care compositions comprises a water-soluble calcium salt, a fluoride-providing agent, and a chelating agent. Methods of treating or preventing dental caries are also provided.

Abstract: A multilayer color-sensing photodetector is fabricated in a semiconductor wafer having a single crystal structure to form a first, second and third layer of single crystal semiconductor material. A dielectric layer is formed that completely surrounds each single crystal region. A blocking layer is applied to prevent ion implantation where not desired. Ions are implanted into a predefined implant area. The semiconductor wafer is heated to create a dielectric layer part way through the single crystal semiconductor region. The second layer of single crystal semiconductor materials is formed by depositing a single crystal or polycrystalline material and annealing it to form a single crystal semiconductor. The deposited semiconductor layer is masked and etched to obtain single crystal regions directly above the previous layer. A blocking layer is applied and an ion implant is performed. After heating, there is left a region of single crystal silicon that has its sides and bottom surrounding by a dielectric border.

Abstract: The present invention is directed to a system and method for managing state information related to an interactive application to accommodate one or more users participating in an interactive application session, wherein the state information comprises local state information specific to each of the one or more user's unique view of the interactive application and global state information. The system of the present invention may comprise a telecommunications network; an application server in communication with the telecommunications network for managing the global state information relative to all of the users participating in the interactive application session; and at least one mobile client device in communication with the application server over the telecommunications network for managing the local state information for each of the one or more users.

Abstract: Skin care compositions containing dehydroacetic acid, its isomers, salts, and derivatives thereof; at least two skin care actives selected from sugar amines, vitamin B3 compounds, phytosterols, salicylic acid compounds, hexamidines, dialkanoyl hydroxyproline compounds, flavonoids, n-acyl amino acid compounds, and their derivatives, and combinations thereof; and a dermatologically acceptable carrier for the dehydroacetic acid and the skin care actives. The invention further relates to methods for regulating the condition of mammalian keratinous tissue wherein the methods each comprise the step of topically applying to the keratinous tissue of a mammal needing such treatment, a safe and effective amount of the skin care composition of the invention.

Abstract: The present invention is directed to a system and method for managing state information related to an interactive application to accommodate one or more users participating in an interactive application session, wherein the state information comprises local state information specific to each of the one or more user's unique view of the interactive application and global state information. The system of the present invention may comprise a telecommunications network; an application server in communication with the telecommunications network for managing the global state information relative to all of the users participating in the interactive application session; and at least one mobile client device in communication with the application server over the telecommunications network for managing the local state information for each of the one or more users.

Abstract: Sidewalls of a pneumatic tire have greater resistance to failure due to dynamic flexing and abrasion, and the tire's tread has better resistance to tearing than with conventionally used rubber compositions, when sidewalls and tread are formed from a compound having a major proportion by weight of synthetic rubber (SR) and a minor proportion by weight of natural rubber (NR), and a major proportion by weight of the SR itself consists essentially of a high cis-1,4-polybutadiene having defined molecular architecture. The high cis-1,4-PBD has more than 90 percent cis-structure, a poly-dispersity in the range from about 3 to 5, a number average molecular weight Mn in the range from 100,000 to 150,000 and a degree of branching in the range from 2 to 3.5. The sidewall compound has characteristics quite different from one made with a typical commercially available high cis-1,4-PBD; and the tread has excellent tear strength.

Abstract: The present invention is directed to a method and system for controlling the state of an interactive application and controlling delivery of the interactive application to one or more users. The system of the present invention is a system for delivering an interactive application to one or more users of a communications network and may comprise an interactive application adapted to the communications network; a user access device adapted to receive said interactive application; control means for establishing parameters under which said interactive application is rendered on said user access device; and mediation means for establishing terms for the interaction between the at least one user and other users and the communications network.

Abstract: A method to provide a skin composition comprising at least one salt-form active which is aesthetically pleasing and effective. The method has the steps of providing a first container for a first aqueous phase having at least one salt-sensitive thickener; a second container for a second aqueous phase having at least one salt-form active; and dispensing the first and second phases from their respective containers onto a common surface. The first and second phases are then blended together and applied to the area of the skin in need of treatment.

Abstract: The present invention is directed to a method and system for controlling the state of an interactive application and controlling delivery of the interactive application to one or more users. The system of the present invention is a system for delivering an interactive application to one or more users of a communications network and may comprise an interactive application adapted to the communications network; a user access device adapted to receive said interactive application; control means for establishing parameters under which said interactive application is rendered on said user access device; and mediation means for establishing terms for the interaction between the at least one user and other users and the communications network.

Abstract: Managing instant messages may include receiving instant messages created by or on behalf of one or more message sources for delivery to an intended recipient. From among the received instant messages, qualifying instant messages may be identified that satisfy a capture rule, and two or more of the qualifying instant messages may be captured. The intended recipient may be informed of the captured instant messages unobtrusively, and also may be enabled to manage the captured instant messages.

Abstract: The invention provides a method for determining the effects of an agent on repolarization of cells in vitro, comprising stimulating the cells with an energy source and under conditions sufficient and for a time sufficient to depolarize the cells, measuring the QT interval of the electrical signals output by the cells in response to the stimulating step, contacting the cells with an agent, re-stimulating the cells with the same energy source and under the same conditions as the first stimulating step and for a time sufficient to depolarize the cells, measuring the QT interval of the electrical signals output by the cells in response to the second stimulating step, and comparing the results of the measuring taken after the first and second stimulating steps to determine whether the agent affects repolarization of cells. The present invention also provides a method for determining the effects of an agent on conduction of cells in vitro.

Abstract: A chewable confectionery dental composition delivering to the mouth a unit dose of a plaque reducing enzyme the composition comprising an enzyme and a non-cariogenic sweetener, the enzyme being incorporated in the composition at a temperature less than about 80° C.

Abstract: This invention provides a composition for delivery of a gene to a syncytial structure comprising stem cells incorporated with the gene. This invention also provides a composition for ion channel transfer which comprises stem cells incorporated with a compound in an amount sufficient to create ion channels. This invention also provides for a method of expressing a functional gene product in a syncytial structure comprising administering a composition, comprising stem cells that have been incorporated with a gene, to the syncytial structure. This invention further provides a method of expressing a functional ion channel in a syncytial structure comprising administering a composition, comprising stem cells that have been incorporated with a compound in an amount sufficient to create ion channels, to the syncytial structure. This invention also provides a composition for delivery of small molecules comprising stem cells incorporated with the small molecules or genes encoding the small molecules.

Abstract: Skin care compositions and methods for regulating the condition of mammalian keratinous tissue containg an effective amount of a dialkanoyl hydroxyproline compound and a second skin care compound selected from hexamidine compounds, sugar amine compounds and their combination. These compositions may be either an emulsion or a solution wherin the dialkanoyl hydroxyproline compound may be converted to its salt for incorporation into the aqueous phase of a compositions.

Abstract: A bed (10) includes a base (12) and a frame assembly (14). A head end support assembly (16) and a foot end support assembly (18) are coupled between the base (12) and the frame assembly (14). The frame assembly (14) includes first and second side frame members (80, 82) located above the base (12). The bed (10) also includes a plurality of latch mechanisms (160) coupled to the first and second side frame members (80, 82), and a patient support surface (162) configured to be coupled to the first and second side frame members (80, 82) by the plurality of latch mechanisms (160). A rotational drive mechanism (130) is coupled to the foot end support assembly (18) to rotate the frame assembly (14) about its longitudinal axis to a prone position. A proning surface (250) is coupled to the frame assembly (14) to support a patient in the prone position.

Abstract: A method and system that provides end users with the ability to exchange routing data. A route recorder application on a first computing system provides a first end user with the ability to define a route formed of specific road segments and store data that represent the route in a data file. The data file is distributed to a second end user who uses the data that represent the route in a second computing system to provide guidance for following the route.