Abstract: Water-soluble azlactone activated polyalkylene oxides having improved hydrolytic stability and conjugates of the azlactone activated polyalkylene oxides with biologically active nucleophiles are disclosed. Methods of forming and conjugating the activated polyalkylene oxides with biologically active nucleophiles are also disclosed.

Abstract: Disclosed are 7-substituted taxoid derivatives, in particular taxol-7-carbazates which have improved water-solubility and/or enhanced therapeutic activity and methods of making the same. The preferred taxoid derivatives have the formula: ##STR1## wherein Z is H or ##STR2## Y=O or S; X=CH.sub.2 or O; n=zero or a positive integer, preferably one; with the proviso that when n=O, X=CH.sub.2 ; R=C.sub.1 -C.sub.4 alkyl, haloalkyl, carboxyalkyl, thioalkyl, sulfonylalkyl, phenyl, hydroxyphenyl, aminophenyl, carboxyphenyl, a polyalkyleneoxide homopolymer or water soluble polyalkyleneoxide containing copolymer, having a molecular weight of from about 1,000 to about 20,000; ##STR3## W=O, N--L, S or SO.sub.2 ; Ph is a phenyl group; L=H, C.sub.1 -C.sub.4 alkyl or phenyl; and R.sub.2 =C.sub.1-C.sub.4 alkyl, phenyl or a polyalkyleneoxide homopolymer or water soluble polyalkyleneoxide containing copolymer, having a molecular weight of from about 1,000 to about 20,000.

Abstract: Water-soluble cyclic imide thione activated polyalkylene oxides having improved hydrolytic stability are disclosed. Methods of forming and conjugating the activated polyalkylene oxides with biologically active nucleophiles are also disclosed.

Abstract: Water-soluble cyclic imide thione activated polyalkylene oxides having improved hydrolytic stability are disclosed. Methods of forming and conjugating the activated polyalkylene oxides with biologically active nucleophiles are also disclosed.

Abstract: Water-soluble azlactone activated polyalkylene oxides having improved hydrolytic stability and conjugates of the azlactone activated polyalkylene oxides with biologically active nucleophiles are disclosed. Methods of forming and conjugating the activated polyalkylene oxides with biologically active nucleophiles are also disclosed.

Abstract: Water-soluble aryl imidate activated polyalkylene oxides having improved hydrolytic stability and conjugates of the aryl imidate activated polyalkylene oxides with biologically active nucleophiles are disclosed. Methods of preparing the activated polyalkylene oxides and conjugates thereof are also disclosed.

Abstract: A single-part aqueous, storage stable, antimicrobial film-forming composition comprising a major portion of water, an antimicrobially effective amount of a cationic germicidal agent having the structure (R) (R.sub.1) (R.sub.2) (R.sub.3) N.sup.+ X.sup.-, wherein R, R.sub.1, R.sub.2, and R.sub.3 are independently selected from groups including benzyl, alkyl, benzyl, halo benzyl, C.sub.1-14 alkyl, C.sub.5-24 alkyl or C.sub.1-4 hydroxyalkyl and X.sup.- represents an anion capable of imparting water solubility or dispersability to the compound, and a stoichemetrically effective amount of acid functional anionic polymer, wherein said cationic germicidal agent and anionic polymer remain dissolved as a homogeneous aqueous solution until used.

Abstract: The present invention provides a liquid composition that yields an abrasion resistant polymeric film on a surface that provides extended protection from microbial growth through slow release of a potent antimicrobial agent. The active ingredient of the liquid composition has the following general formula: ##STR1## wherein R=H, (C.sub.1 -C.sub.1)alkyl, --COOH, --CH.sub.2 --COOH, --C.sub.6 H.sub.11, or -phenyl;R'=H, or (C.sub.1 -C.sub.3)alkyl, --CH.sub.2 --COOH, --C.sub.6 H.sub.11, or -phenyl;R"=H, or (C.sub.1 -C.sub.5)alkyl; andX=a single bond; ##STR2## where m=2-4; and Z=H or (C.sub.1 -C.sub.3)alkyl;as well as homopolymers, copolymers, or terpolymers comprising said active ingredient.

Abstract: An improved softening agent dispersed in an aqueous detergent comprising droplets having an exterior organic phase containing a complexing agent and an inner aqueous phase comprising an acid or salt. The ability of the softening agent to remove hardness ions is improved by a novel complexing agent.

Abstract: The present invention provides a liquid composition that yields an abrasion resistant polymeric film on a surface that provides extended protection from microbial growth through slow release of a potent antimicrobial agent. The active ingredient of the liquid composition has the following general formula: ##STR1## wherein R=H, (C.sub.1 -C.sub.3)alkyl, --COOH, --CH.sub.2 --COOH, --C.sub.6 H.sub.11, or -phenyl;R'=H, (C.sub.1 -C.sub.3)alkyl, --CH.sub.2 --COOH, --C.sub.6 H.sub.11, or -phenyl;R"=H, or (C.sub.1 -C.sub.5)alkyl; andX=a single bond; ##STR2## where m=2-4; andZ=H or (C.sub.1 -C.sub.3)alkyl; as well as homopolymers, copolymers, or terpolymers comprising said active ingredient.

Abstract: A composition having a high chelation value may be made by blending about 50 to 80 wt-% of a polyether such as polyethylene glycol, about 20 to 50 wt-% of a polycarboxylate such as polyacrylate moiety or an acrylate monomer, and about 0.1 to 0.5 mole-%, based upon the polyacrylate moiety or the monomer, of an organic peroxy catalyst such as t-butyl perbenzoate at a temperature below about 110.degree. C. but sufficient to liquefy the blend and cause grafting of a polyether on the polycarboxylate.

Abstract: A uniform, continuous sanitizing film can be formed by simultaneously spraying a two-package aqueous sanitizing composition comprising in a first solution a quaternary ammonium salt compound and in a second solution a polymer containing acid functionality. The sprays are directed to areas of substantial overlap resulting in a reaction between the quaternary ammonium compound and the carboxylic acid functional polymeric compound resulting in formation of a water insoluble film.

Abstract: Alkanes containing an intralinear sulfonyl group and a cyano group separated by a single carbon substituted with at least one hydrogen atom are employed as silver halide solvents in photographic processes and compositions.

Abstract: This invention is concerned with the synthesis of perfluorodialdehydes from the corresponding perfluorodiesters and with intermediates useful in the preparation of the perfluorodialdehydes.

Abstract: Difunctional compounds wherein one of said functions is a hard or soft atom that ionizes to the corresponding anion in alkaline solution to combine with silver cation and the other of said functions is a non-ionizable soft base that additionally combines with said silver cation are employed as silver halide complexing agents in photography. In a preferred embodiment, the difunctional compounds possess (a) an O, N or C atom that ionizes to the corresponding O.crclbar., N.crclbar. or C.crclbar. anion in basic solution and (b) an --S-- containing moiety excluding --SH and moieties that form --S.crclbar. in basic solution wherein the --S-- of said moiety is positioned alpha, beta, gamma, delta, epsilon or zeta to said anion.

Abstract: Difunctional compounds wherein one of said functions is a hard or soft atom that ionizes to the corresponding anion in alkaline solution to combine with silver cation and the other of said functions is a non-ionizable soft base that additionally combines with said silver cation are employed as silver halide complexing agents in photography. In a preferred embodiment, the difunctional compounds possess (a) an O, N or C atom that ionizes to the corresponding O.sup..crclbar., N.sup..crclbar. or C.sup..crclbar. anion in basic solution and (b) an --S-- containing moiety excluding --SH and moieties that form --S.sup..crclbar. in basic solution wherein the --S-- of said moiety is positioned alpha, beta, gamma, delta, epsilon or zeta to said anion.

Abstract: The present invention is concerned with novel compounds useful as photographic silver halide complexing agents and with their photographic use. The subject compounds are represented by the formulas ##STR1## wherein one of R.sup.1 and R.sup.2 is --CH.sub.2).sub.x SR.sup.3 and the other of said R.sup.1 and R.sup.2 is --CH.sub.2).sub.y SR.sup.3 wherein R.sup.3 is alkyl, x is a whole number 0 or 1 and y is a whole number from 0 to 5.

Abstract: In one embodiment, the present invention relates to pyrazolidine derivatives, some of which are novel compounds, all of which are represented by the formula: ##STR1## wherein R.sup.1 and R.sup.2 taken individually, the same or different, are each hydrocarbon moieties containing up to about 20 carbon atoms selected from alkyl, aryl, aralkyl and alkaryl, which moieties may be unsubstituted or substituted with a substituent selected from carboalkoxyalkyl, aryl, alkyl, alkoxy, hydroalkyl, aminoalkyl, ketalalkyl and acetalalkyl, and R.sup.1 and R.sup.2 taken together represent the carbon atoms necessary to complete a cyclic moiety selected from: ##STR2## which cyclic moieties may be unsubstituted or substituted with the above-identified substituents; Y is --OH or --NH.sub.2 ; and X is --OH, --NH.sub.2, --NH.sub.2.Z where Z is a salt, or --NHR where R is alkyl or aryl.

Abstract: Difunctional compounds wherein one of said functions is a hard or soft atom that ionizes to the corresponding anion in alkaline solution to combine with silver cation and the other of said functions is a non-ionizable soft base that additionally combines with said silver cation are employed as silver halide complexing agents in photography. In a preferred embodiment, the difunctional compounds possess (a) an O, N or C atom that ionizes to the corresponding O.sup..crclbar., N.sup..crclbar. or C.sup..crclbar. anion in basic solution and (b) an --S-- containing moiety excluding --SH and moieties that form --S.sup..crclbar. in basic solution wherein the --S-- of said moiety is positioned alpha, beta, gamma, delta, epsilon or zeta to said anion.

Abstract: This application is directed to a novel cleavage reaction whereby N-tosylsulfoximides of the following formula are converted to the corresponding sulfoximines. The relevant sulfoximides are represented by the formula: ##STR1## wherein R.sup.1 and R.sup.2 when taken individually (1) each represent an alkyl moiety containing up to 20 carbon atoms, unsubstituted with an alkali-stable group or (2) R.sup.1 is an alkyl moiety containing up to 20 carbon atoms and R.sup.2 is --(CH.sub.2).sub.n --S--R.sup.3 wherein n is greater than or equal to 2 and R.sup.3 is an alkyl moiety containing up to 20 carbon atoms and R.sup.1 and R.sup.2 when taken together represents (a) an alkylene moiety having 5 or 6 carbon atoms unsubstituted or substituted with an alkali-stable group; (b) --CH.sub.2 --.sub.x SO.sub.2 --CH.sub.2 -- wherein x is 3 or 4; or (c) --CHR--SO.sub.2 --CH.sub.2 CR'R"CH.sub.