Patents by Inventor Richard Gross

Richard Gross has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment and prophylaxis of sepsis and septic shock
    Patent number: 7772193
    Abstract: A method and composition for the prophylaxis or treatment of humans or animals for septic shock and sepsis using a mixture of sophorolipids.
    Type: Grant
    Filed: March 26, 2007
    Date of Patent: August 10, 2010
    Assignee: Polytechnic University of NYU
    Inventor: Richard A. Gross
  • Lung Injury Treatment
    Publication number: 20100130442
    Abstract: Techniques for lung injury treatment are provided. For example, a technique for treating a lung injury in a patient includes the step of administering a therapeutically effective amount of a sophorolipid to the patient.
    Type: Application
    Filed: May 6, 2008
    Publication date: May 27, 2010
    Inventors: Raj Wadgaonkar, Richard A. Gross, Daniel Butnariu, Vipul Patel, Kaumudi Somnay
  • ENZYME-CATALYZED POLYCARBONATE AND POLYCARBONATE ESTER SYNTHESIS
    Publication number: 20100041856
    Abstract: An enzymatic process for preparing aliphatic polycarbonates via terpolymerization or transesterification using a dialkyl carbonate, an aliphatic diester, and an aliphatic diol or triol reactant. A catalyst having an enzyme capable of catalyzing an ester hydrolysis reaction in an aqueous environment is subsequently added to the reaction mixture. Next, polymerization of the reaction proceeds for an allotted time at a temperature?100° C. Finally, the copolymer is isolated from an the catalyst via filtration.
    Type: Application
    Filed: August 15, 2008
    Publication date: February 18, 2010
    Inventors: Richard A. Gross, Zhaozong Jiang
  • Container Closure With Segmented Fusion Ring
    Publication number: 20090314777
    Abstract: A container provides sealed storage for contents. The container includes a composite top member formed of a panel and a frame. The panel includes an opening for providing access to the contents of the package. The frame includes a closure member that is molded in an open position, and which can be moved to a closed position for closing the opening in the panel. The container is formed of a container body in the form of a tubular member formed to a desired shape. The container body is closed using the top member that closes a top opening of the container body, and a bottom member that closes a bottom opening of the container body.
    Type: Application
    Filed: August 3, 2009
    Publication date: December 24, 2009
    Inventors: Richard A. Gross, Dieter F. Lay, Robert W. Fox
  • Multi-Component Product Container With Reclosable Top
    Publication number: 20090314415
    Abstract: A container provides sealed storage for contents. The container includes a composite top member formed of a panel and a frame. The panel includes an opening for providing access to the contents of the package. The frame includes a closure member that is molded in an open position, and which can be moved to a closed position for closing the opening in the panel. The container is formed of a container body in the form of a tubular member formed to a desired shape. The container body is closed using the top member that closes a top opening of the container body, and a bottom member that closes a bottom opening of the container body.
    Type: Application
    Filed: August 3, 2009
    Publication date: December 24, 2009
    Inventors: Richard A. Gross, Dieter F. Lay, Robert W. Fox
  • Multi-Component Packaging System And Method For Manufacture
    Publication number: 20090302040
    Abstract: A storage means provides sealed storage for contents. A closure means is fused to a container by application of an electro-magnetic field providing a permanent and hermetic seal between the closure and the container. The closure further includes a removable panel to provide access to the contents of the container.
    Type: Application
    Filed: August 18, 2009
    Publication date: December 10, 2009
    Inventors: Robert W. Fox, Dieter F. Lay, Richard A. Gross
  • Hydroxyphenyl cross-linked macromolecular network and applications thereof
    Publication number: 20090252700
    Abstract: A synthetic nucleus pulposus is provided that is useful in treatment of degenerative disc disease, augmentation of a degenerate disc, and alleviation of back pain. In an embodiment the synthetic nucleus pulposus comprises hyaluronan macromolecules that have been cross-linked via dihydroxyphenyl linkages. The synthetic nucleus pulposus restores or improves the water-retention capability of the disc. A method of treating an intervertebral disc with the cross-linked hyaluronan macromolecules is also provided. A method of regenerative therapy to address loss of cells of nucleus pulposus of an intervertebral disc based on treatment with the cross-linked hyaluronan macromolecules and mesenchymal stem cells is also provided.
    Type: Application
    Filed: February 27, 2009
    Publication date: October 8, 2009
    Applicant: The Cleveland Clinic Foundation
    Inventors: Peter A. Zahos, Anthony Calabro, Aniq B. Darr, Richard A. Gross
  • Multi-component product container with reclosable top
    Patent number: 7568590
    Abstract: A container provides sealed storage for contents. The container includes a composite top member formed of a panel and a frame. The panel includes an opening for providing access to the contents of the package. The frame includes a closure member that is molded in an open position, and which can be moved to a closed position for closing the opening in the panel. The container is formed of a container body in the form of a tubular member formed to a desired shape. The container body is closed using the top member that closes a top opening of the container body, and a bottom member that closes a bottom opening of the container body.
    Type: Grant
    Filed: November 23, 2004
    Date of Patent: August 4, 2009
    Assignee: Arrow Innovations, LLC
    Inventors: Richard A. Gross, Dieter F. Lay, Robert W. Fox
  • METHOD FOR NEUTRALIZING FUNGI USING SOPHOROLIPIDS AND ANTIFUNGAL SOPHOROLIPIDS FOR USE THEREIN
    Publication number: 20090186836
    Abstract: 17-L-[(2?-O-?-D-glucopyranosyl-?-D-glucopyranosyl)-oxy]-cis-9-octa-decenoate, lactonic and open ring 17-L-[(2?-O-?-D-glucopyranosyl-?-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, methyl 17-L-[(2?-O-?-D-glucopyranosyl-?-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, ethyl 17-L-[(2?-O-?-D-glucopyranosyl-?-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, hexyl 17-L-[(2?-O-?-D-glucopyranosyl-?-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, ethyl 17-L-[(2?-O-?-D-glucopyranosyl-?-D-glucopyranosyl)-oxy]-cis-9-octadecenoate-6?-acetate and ethyl 17-L-[(2?-O-?-D-glucopyranosyl-?-D-glucopyranosyl)-oxy]-cis-9-octadecenoate-6?,6?-diacetate sophorolipids and uses thereof as antifungal agents.
    Type: Application
    Filed: January 27, 2009
    Publication date: July 23, 2009
    Inventors: Richard A. Gross, Vishal Shah
  • TREATMENT AND PROPHYLAXIS OF CANCER
    Publication number: 20090186835
    Abstract: A method and composition for the prophylaxis or treatment of humans or animals for cancer using a mixture of sophorolipids.
    Type: Application
    Filed: January 14, 2009
    Publication date: July 23, 2009
    Inventors: Richard A. Gross, Martin H. Bluth
  • EMBEDDED ENZYMES IN POLYMERS TO REGULATE THEIR DEGRADATION RATE
    Publication number: 20090162337
    Abstract: A biodegradable material, capable of carrying a bioactive agent, comprising a polymer matrix and an enzyme capable of degrading the polymer matrix to enable the release of the bioactive agent.
    Type: Application
    Filed: August 7, 2008
    Publication date: June 25, 2009
    Inventors: Richard A. Gross, Rachna Dave, Arthur Martin
  • Hydroxyphenyl cross-linked macromolecular network and applications thereof
    Publication number: 20090142309
    Abstract: A dihydroxyphenyl cross-linked macromolecular network is provided that is useful in artificial tissue and tissue engineering applications, particularly to provide a synthetic macromolecular network for a wide variety of tissue types. In particular, artificial or synthetic cartilage, vocal cord material, vitreous material, soft tissue material and mitral valve material are described. In an embodiment, the network is composed of tyramine-substituted and cross-linked hyaluronan molecules, wherein cross-linking is achieved via peroxidase-mediated dityramine-linkages that can be performed in vivo. The dityramine bonds provide a stable, coherent hyaluronan-based hydrogel with desired physical properties.
    Type: Application
    Filed: January 29, 2009
    Publication date: June 4, 2009
    Applicant: The Cleveland Clinic Foundation
    Inventors: Anthony Calabro, Lee Akst, Daniel Alam, James Chan, Aniq B. Darr, Kiyotaka Fukamachi, Richard A. Gross, David Haynes, Keiji Kamohara, Daniel P. Knott, Hilel Lewis, Alex Melamud, Anthony Miniaci, Marshall Strome
  • Hydroxyphenyl cross-linked macromolecular network and applications thereof
    Publication number: 20090143766
    Abstract: A dihydroxyphenyl cross-linked macromolecular network is provided that is useful in artificial tissue and tissue engineering applications, particularly to provide a synthetic macromolecular network for a wide variety of tissue types. In particular, artificial or synthetic cartilage, vocal cord material, vitreous material, soft tissue material and mitral valve material are described. In an embodiment, the network is composed of tyramine-substituted and cross-linked hyaluronan molecules, wherein cross-linking is achieved via peroxidase-mediated dityramine-linkages that can be performed in vivo. The dityramine bonds provide a stable, coherent hyaluronan-based hydrogel with desired physical properties.
    Type: Application
    Filed: January 29, 2009
    Publication date: June 4, 2009
    Applicant: The Cleveland Clinic Foundation
    Inventors: Anthony Calabro, Lee Akst, Daniel Alam, James Chan, Aniq B. Darr, Kiyotaka Fukumachi, Richard A. Gross, David Haynes, Keiji Kamohara, Daniel P. Knott, Hilel Lewis, Alex Melamud, Anthony Miniaci, Marshall Strome
  • Acrylated Hyaluronic Acid
    Publication number: 20090118423
    Abstract: The present invention relates to an acrylated hyaluronic acid product and to processes for the production thereof.
    Type: Application
    Filed: March 9, 2007
    Publication date: May 7, 2009
    Applicant: Novozymes Biopolymer A/S
    Inventors: Vineet Kumar, Richard A. Gross
  • DISPOSABLE PROPHY ANGLE GRIP
    Publication number: 20090081609
    Abstract: A disposable prophy angle for mounting on a powered dental handpiece with an elastomeric grip where the elastomer of the grip is disposed along the back of the neck, the back of the shoulder, and about the base of the device so that the prophy angle may be comfortably grasped by the fingers and thumb of a user, so that it will resist slippage from the user's hand, and so that it will tactilely direct the user's fingers and thumb into the proper position to handle the prophy angle in an effective manner.
    Type: Application
    Filed: September 24, 2007
    Publication date: March 26, 2009
    Applicant: Sunstar Americas, Inc.
    Inventors: Russell Glen Kalbfeld, Richard Gross, Randy Soibel
  • METHOD OF SELLING DOSAGE FORMS WITHOUT A PRESCRIPTION
    Publication number: 20090057187
    Abstract: The invention features a method of selling dosage forms without a prescription by displaying said dosage forms in a container having an asymmetric shape.
    Type: Application
    Filed: February 21, 2008
    Publication date: March 5, 2009
    Inventors: Mary Toth, Javier Verdura, Craig Pirie, Daniel Peter Sterling, Erik Joseph Moses, Peter Michaelian, Richard A. Gross, Dieter F. Lay, Roger Rinker, Kristin Recchiuti, Leonard Wojnarowicz, JR., John Spano
  • METHOD FOR PREPARING LONG-CHAIN HYDROXYACIDS, DIACIDS AND OLIGOMERS AND POLYMERS THEREOF
    Publication number: 20090054610
    Abstract: A method and process for the preparation of ricinoleic acid analogs and oligomers and polymers containing such ricinoleic acid analogs.
    Type: Application
    Filed: August 21, 2008
    Publication date: February 26, 2009
    Inventors: Richard A. Gross, Wenhua Lu, Yixin Yang
  • ENZYME-CATALYZED POLYCARBONATE AND POLYCARBONATE ESTER SYNTHESIS
    Publication number: 20090047717
    Abstract: An enzymatic process for preparing aliphatic polycarbonates via terpolymerization or transesterification using a dialkyl carbonate, an aliphatic diester, and an aliphatic diol or triol reactant. A catalyst having an enzyme capable of catalyzing an ester hydrolysis reaction in an aqueous environment is subsequently added to the reaction mixture. Next, polymerization of the reaction proceeds for an allotted time at a temperature ?100° C. Finally, the copolymer is isolated from an the catalyst via filtration.
    Type: Application
    Filed: August 18, 2008
    Publication date: February 19, 2009
    Inventors: Richard A. Gross, Zhaozong Jiang
  • Hydroxyphenyl cross-linked macromolecular network and applications thereof
    Publication number: 20090042294
    Abstract: A dihydroxyphenyl cross-linked macromolecular network is provided that is useful in artificial tissue and tissue engineering applications, particularly to provide a synthetic macromolecular network for a wide variety of tissue types. In particular, artificial or synthetic cartilage, vocal cord material, vitreous material, soft tissue material and mitral valve material are described. In an embodiment, the network is composed of tyramine-substituted and cross-linked hyaluronan molecules, wherein cross-linking is achieved via peroxidase-mediated dityramine-linkages that can be performed in vivo. The dityramine bonds provide a stable, coherent hyaluronan-based hydrogel with desired physical properties.
    Type: Application
    Filed: September 15, 2008
    Publication date: February 12, 2009
    Applicant: The Cleveland Clinic Foundation
    Inventors: Anthony Calabro, Lee Akst, Daniel Alam, James Chan, Aniq B. Darr, Kiyotaka Fukamachi, Richard A. Gross, David Haynes, Keiji Kamohara, Daniel P. Knott, Hilel Lewis, Alex Melamud, Anthony Miniaci, Marshall Strome
  • Dispensing closure for container
    Patent number: D608199
    Type: Grant
    Filed: February 19, 2009
    Date of Patent: January 19, 2010
    Assignee: Portola Packaging, Inc.
    Inventor: Richard Gross