Abstract: Embodiments of the invention provide a user-operated directional controller for an electronic device. One embodiment provides an apparatus that includes a pointing device which receives raw signal data in an electronic device, one or more processors, and logic encoded in one or more tangible media for execution by the one or more processors and when executed operable to: determine a first coordinate value for a cursor position by reading x, y coordinate values from a directional controller; determine a remainder value associated with the first coordinate value; store the remainder value; determine a second coordinate value for a second cursor position by reading x, y coordinates from the directional controller; compute the second coordinate value by using a residual value, wherein the residual value is derived from the stored remainder value from a previous calibration operation; and store the subsequent remainder value.

Abstract: A single line docking station characteristic identifier is disclosed. In one embodiment, a portable computing device can include a dock detector circuit having an interface pin configured to be coupled to a docking station via a single line dock connection, where the dock detector circuit is configured to determine a characteristic of the docking station using a passive component in the docking station when the portable computing device is connected to the docking station via the single line dock connection. The dock detector circuit can include a resistor and a Schmitt trigger, while the passive component in the docking station can include a capacitor, for example.

Abstract: The invention relates to anti-Factor D antibodies, their nucleic acid and amino acid sequences, the cells and vectors that harbor these antibodies and their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation. These antibodies are useful for diagnostics, prophylaxis and treatment of disease.

Abstract: A battery type detection approach is disclosed. In one embodiment, a method of detecting a battery type can include: receiving a signal from a battery module in a portable computing device; determining if the signal is in a first state for at least a first predetermined time before transitioning to a second state; determining if the signal transitions from the second state to the first state after a second predetermined time, and identifying the battery type in response thereto; and asserting an indication of the battery type when a third predetermined time period after the transition from the second state to the first state has occurred.

Abstract: A subprocessor is used to interface between subsystems and to reduce the amount of dedicated hardware used to implement the subsystems in a hand-held computer. The subprocessor includes basic processing system resources such as random-access memory (RAM), read-only memory (ROM), a processor, input/output (I/O) facilities, etc. Selected functions in subsystems are achieved by firmware instructions executed by the subprocessor as opposed to a main processor that is also used in the computer. This approach can provide efficiencies such as low power consumption, less required space, less routing overhead, easier transfer of inter-subsystem information, and other advantages.

Abstract: The present invention relates to polypeptides that inhibit APRIL and/or BAFF binding to BCMA, nucleic acid molecules encoding the polypeptides, and compositions comprising the polypeptides. The present invention also relates to methods for treating an immune-related disease or cancer using the polypeptides and compositions of the invention. The present invention also relates to methods for identifying inhibitors of APRIL/BAFF binding to BCMA and APRIL/BAFF signaling.

Abstract: Anti-polyubiquitin monoclonal antibodies, and methods for using the antibodies, are provided.

Abstract: Methods of making Apo-2 ligand and formulations of Apo-2 ligand using divalent metal ions are provided. Such divalent metal ions include zinc and cobalt which improve Apo-2 ligand trimer formation and stability. The crystal structure of Apo-2 ligand is also provided, along with Apo-2 ligand variant polypeptides identified using oligonucleotide-directed mutagenesis.

Abstract: A computing device that includes a host processor and a service processor is provided. The host processor is configured to interact with a first user interface. For example, the host processor may be a microprocessor for the device and the first user interface may be a display device. A service processor is provided and can interact with a second user interface. In some cases, the service processor may interact with the second user interface without communicating with the host processor. Accordingly, the service processor can perform functions without relying on the host processor. Using the service processor conserves processing power and also may allow the reduction in size of the device as the service processor may perform the functions previously performed by discrete hardware and the host processor.

Abstract: A portable computing device with hybrid hardware/firmware accelerometers for pointer control and user interface is disclosed. In one embodiment, a portable computing device can include: (i) at least one accelerometer; and (ii) an embedded controller coupled to the accelerometer, where the embedded controller can change a parameter or variable of the portable computing device when a predetermined condition is detected by the accelerometer. The predetermined condition can include a tilt of the portable computing device, and the parameter that is changed can be a game piece property, for example.

Abstract: A single line docking station characteristic identifier is disclosed. In one embodiment, a portable computing device can include a dock detector circuit having an interface pin configured to be coupled to a docking station via a single line dock connection, where the dock detector circuit is configured to determine a characteristic of the docking station using a passive component in the docking station when the portable computing device is connected to the docking station via the single line dock connection. The dock detector circuit can include a resistor and a Schmitt trigger, while the passive component in the docking station can include a capacitor, for example.

Abstract: A portable computing device with hybrid hardware/firmware accelerometers for drop and tumble detect is disclosed. In one embodiment, a portable computing device can include: (i) a plurality of accelerometers; and (ii) an embedded controller coupled to the plurality of accelerometers, where the embedded controller can change the portable computing device from a first state to a second state when a predetermined condition is detected by at least one of the plurality of accelerometers. The predetermined condition can include a dropping, tumbling, or free fall situation. Also, the first state can be an active state, while the second state can be a protective state, such as where a hard drive is shut down, for example.

Abstract: The disclosure provides Apo-2 ligand variant polypeptides. Methods of making and chemically modifying Apo-2 ligand variant polypeptides are also provided. In addition, formulations of Apo-2 ligand variant polypeptides are provided. In addition, therapeutic methods for using Apo-2 ligand variant polypeptides are provided.

Abstract: A subprocessor is used to interface between subsystems and to reduce the amount of dedicated hardware used to implement the subsystems in a hand-held computer. The subprocessor includes basic processing system resources such as random-access memory (RAM), read-only memory (ROM), a processor, input/output (I/O) facilities, etc. Selected functions in subsystems are achieved by firmware instructions executed by the subprocessor as opposed to a main processor that is also used in the computer. This approach can provide efficiencies such as low power consumption, less required space, less routing overhead, easier transfer of inter-subsystem information, and other advantages.

Abstract: A hollow component for gas turbine engine, for example an outlet guide vane, is assembled from a body having at recessed pocket formed therein, and an aerodynamic cover bonded over the pocket. Both the cover and the body are constructed from materials which are not readily fusion weldable. The cover is attached to the body by a solid state bonding process, for example friction stir welding. The hollow component may also be built up from multiple individual components which are bonded to each other by a solid state bonding process such as friction stir welding.

Abstract: The disclosure provides Apo-2 ligand variant polypeptides. Methods of making and chemically modifying Apo-2 ligand variant polypeptides are also provided. In addition, formulations of Apo-2 ligand variant polypeptides are provided. In addition, therapeutic methods for using Apo-2 ligand variant polypeptides are provided.