Abstract: The present invention encompasses compounds of the formula (I), wherein the variables are defined herein which are suitable for the modulation of ROR? and the treatment of diseases related to the modulation of ROR?. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.

Abstract: The invention relates to compounds of Formula I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for method for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of cryptosporidiosis by administering such a compound.

Abstract: A method of forming bundles of glass articles is provided. The method includes transporting individual glass articles to an insert building station using a conveying system. The glass articles are individually located within article receiving slots of a layer separation insert using the conveying system. Each slot of the layer separation insert receives a single glass article forming a glass article layer of side-by-side glass articles. Multiple glass article layers including layer separation inserts are stacked using the conveying system forming a bundle. The layer separation inserts provide a barrier between adjacent glass articles of each of the glass article layers to inhibit glass-to-glass contact.

Abstract: Embodiments of the present disclosure provide an electrical apparatus, a power supply system having the same and a method of manufacturing the electrical apparatus. The electrical apparatus includes a detecting circuit coupled to a generator and configured to detect a frequency of the generator. The electrical apparatus also includes a controller coupled to the detecting circuit and configured to receive a first signal indicating the detected frequency and adjust the frequency of the generator in response to determining that the detected frequency is out of a predetermined frequency range. In this way, an actively controlling of the changing rate of the power to and from generator may be achieved, if the generator frequency exceeds the configured limits.

Abstract: An apparatus for pressure testing a plumbing system, including a fluid pump; a conduit assembly coupled to the fluid pump, a control system communicatively coupled to the conduit assembly to operate the conduit assembly according to a preset operating schedule to acquire a set of pressure data; and an input-output communications device communicatively coupled to the control system to receive a set of pressure data and provide the set of pressure data to a user.

Abstract: The present invention relates to bioactive compositions (including, for example, bioactive serum fractions and bioactive extracts) derived from ginseng (Panax spp.) fresh whole plant, a particular part of the plant (e.g., rhizome, roots, leaves, stems, flowers, fruit) or any combination of these plant parts. The bioactive serum fractions and bioactive extracts are free of or substantially free of pulegone and/or free of or substantially free of proteins. The present invention also provides products comprising the bioactive serum fractions and/or bioactive extracts. The present invention further provides methods of making and using the bioactive serum fractions and/or bioactive extracts. Further, the bioactive serum fractions and bioactive extracts have anti-inflammatory and/or anti-irritant and/or anti-aging activities.

Abstract: The invention relates to thermoplastic molding compounds having melt viscosities of less than 30,000 mPas for use as a hot-melt adhesive, comprising the components A and B, wherein component A comprises one or more C3/C2 copolymers each produced with metallocene catalysts and each having a melt viscosity at 170° C. of less than 20,000 mPas, measured according to DIN 53019, and a molecular weight MW of 1000 g/mol to 50,000 g/mol, and component B comprises one or more C2/C3 copolymers each produced with metallocene catalysts and each having a melt flow index MI of 1 to 100 g/min, measured at 190° C./2.16 kg, according to ASTM D 1238, and a molecular weight MW of 50,000 g/mol to 300,000 g/mol. Said thermoplastic molding compounds, because of the viscosity and mechanical properties thereof, are suitable for fiber mesh applications.

Abstract: A method is provided for safely executing dynamically generated code to avoid the possibility of an attack in unprotected memory space. Upon ascertaining that dynamically generated code is to be executed, a processing circuit and/or operating system kernel restrict the dynamically generated code to use a first memory region within an unprotected memory space, where the first memory region is distinct (e.g., reserved) from other memory regions used by other processes executed by the processing circuit. A first processing stack is maintained for the dynamically generated code within the first memory region. This first processing stack is separate from a general processing stack used by other processes executed by the processing circuit. A stack pointer is switched/pointed to the first processing stack when the dynamically generated code is executed and the stack pointer is switched/pointed to the general processing stack when the dynamically generated code ends.

Abstract: The present invention encompasses compounds of the formula (I), wherein the variables are defined herein which are suitable for the modulation of ROR? and the treatment of diseases related to the modulation of ROR?. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.

Abstract: The invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1 to R7, A, Y and L are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

Abstract: The present invention provides bioactive serum fractions and bioactive extracts derived from an Achachairu (Garcinia humilis) plant. The bioactive serum fractions and bioactive extracts are free of or substantially free of benzophenone and/or free of or substantially free of proteins. The present invention also provides products comprising the bioactive serum fractions and/or bioactive extracts. The present invention further provides methods of making the bioactive serum fractions and/or bioactive extracts.

Abstract: The invention provides compounds of Formula (I) as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections, particularly infections caused by herpesviruses.

Abstract: A closure mechanism and a method for plugging a flow control device of a well is provided. The closure mechanism includes a switch having a hollow interior and a U-shaped portion. The closure mechanism also includes a metal insert located within a portion of the hollow interior of the switch. The mechanism further includes a heating device positioned within the well. In the method, the heating device is activated in the well and melts at least a portion of the metal insert. The melted portion of the metal insert collects and re-solidifies within the U-shaped portion of the switch, thereby closing the switch and plugging the flow control device against flow.

Abstract: Systems, devices, media, methods, and kits are disclosed to integrate and exchange information of analyte analysis kits. Analyte analysis can be performed and presented using in association with advertising or questions.

Abstract: The invention relates to compounds of formula (I), and pharmaceutically acceptable salts thereof, wherein R1 to R7, A, Y and L are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

Abstract: Provided in some embodiments is a well torpedo system that includes a torpedo adapted to be advanced in a wellbore of a subterranean well. The torpedo including an integrated spool adapted to hold a fiber-optic (FO) umbilical including a FO line adapted to couple to a surface component, and an engine adapted to combust solid propellant to generate thrust to propel advancement of the torpedo in the wellbore.

Abstract: A computerized system for associating RF signals, the system including at least one sensor configured to sense a plurality of RF signals at at least a plurality of points in time and a computerized associator receiving outputs from the at least one sensor and providing an output which associates at least some of the plurality of RF signals with at least one unique multiple RF signal-based identifier.

Abstract: The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts therefore, wherein R1 to R6, A, U, V, W, X, Y, and Z are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

Abstract: Provided in some embodiments is a well torpedo system that includes a torpedo adapted to be advanced in a wellbore of a subterranean well. The torpedo including an integrated spool adapted to hold a fiber-optic (FO) umbilical including a FO line adapted to couple to a surface component, and an engine adapted to combust solid propellant to generate thrust to propel advancement of the torpedo in the wellbore.

Abstract: Systems, devices, media, methods, and kits are disclosed to integrate and exchange information of analyte analysis kits. Analyte analysis can be performed and presented using in association with advertising or questions.