Abstract: A presentation assembly for a gaming machine, the presentation assembly comprising a display device, at least one light-emitting device positioned adjacent the display device, and a reflective surface facing the at least one light-emitting device. The reflective surface includes at least one convex surface element extending towards the at least one light-emitting device. The convex surface elements are configured to reflect at least a portion of light emitted by the light-emitting devices towards a predetermined area associated with the gaming machine.

Abstract: A cover for covering an opening defined in a surface, the opening defined between a first edge and a second edge, and defining an opening width therebetween, shorter than a length of the opening, the cover having a cover width and configured to be supported, in use, at the first edge and the second edge of the opening when the cover width is parallel to the opening width, wherein the cover width is adjustable from a first cover width to a second cover width, and wherein the cover is configured to maintain the cover width at the second cover width, in use.

Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Sortilin protein, e.g., human Sortilin or a mammalian Sortilin, and use of such compostions in preventing, reducing risk, or treating an individual in need thereof.

Abstract: Anti-mesothelin antibodies and conjugates comprising such antibodies are disclosed herein as well as the use of such conjugates in the treatment of disease, such as cancer.

Abstract: A heat exchanger (1) for a motor vehicle (2), has first flat tubes (3) with a first longitudinal end (4) received in associated first openings (5) of a first collector (6) and with an opposite second longitudinal end (7) in associated second openings (8) of a second collector (9). Second flat tubes (10) have a first longitudinal end (11) received in associated third openings (12) of a third collector (13) and a second longitudinal end (15) in associated fourth openings (16) of the second collector (9). Only the first flat tubes (3) or both the first and second flat tubes (3, 10) have an angled end region (14). The second and fourth openings (8, 16) are arranged spaced apart from one another with heat transfer fins (18) in between.

Abstract: Methods and compositions for the manufacture and use of a detection apparatus based on one or more native biological nanopores are provided. Uses include, but are not limited to, detection and sequencing of nucleic acids.

Abstract: The present invention concerns a flow cell electrolyzer (1) to electrochemically reduce reagent gas CO2 into gaseous CO, with an anodic compartment comprising an anode (2) with a current collector, and on the current collector, at least a catalyst to electrochemically oxidize H2O to O2, an anodic electrolyte solution (3) at a controlled flow rate Qa, comprising: a solvent, and an anodic electrolyte, the solvent being water at neutral or basic pH; a cathodic compartment comprising a cathodic electrolyte solution (6), at a controlled flow rate Qc, comprising: the solvent, and a cathodic electrolyte, the solvent being water at neutral or basic pH, a gas diffusion porous cathode (9) which comprises, on a gas diffusion porous current cathode collector which is electrochemically inert, at least a molecular catalyst on a surface S to electrochemically reduce CO2 into CO, with a by-production of H2, the molecular catalyst being chosen between the list with the metal chosen among: Iron, Cobalt: metal porphyrin with on

Abstract: A three-dimensional printing system includes a resin vessel containing resin, an imaging bar, a movement mechanism coupled to the imaging bar, and a controller. The imaging bar includes an arrangement of light emitting devices that selectively emit radiation from an exit surface of the imaging bar to define a build plane in the resin. The exit surface of the imaging bar is preferably less than 10 millimeters from the build plane. The controller is configured to scan the imaging bar along a scan axis and, concurrent with scanning, operate the imaging bar to selectively image a layer of resin at the build plane.

Abstract: The invention relates to strong hydrogen-bond acidic sorbents. The sorbents may be provided in a form that limits or eliminates intramolecular bonding of the hydrogen-bond acidic site between neighboring sorbent molecules, for example, by providing steric groups adjacent to the hydrogen-bond acidic site. The hydrogen bond site may be a phenolic structure based on a bisphenol architecture. The sorbents of the invention may be used in methods for trapping or detecting hazardous chemicals or explosives.

Abstract: The present invention provides methods of treating arrhythmogenic cardiomyopathy (ACM) by administration of a thiadiazolidindione or a derivative thereof such as for example tideglusib or NPE 100928.

Abstract: The invention provides a body-worn monitor featuring a processing system that receives a digital data stream from an ECG system. A cable houses the ECG system at one terminal end, and plugs into the processing system, which is worn on the patient's wrist like a conventional wristwatch. The ECG system features: i) a connecting portion connected to multiple electrodes worn by the patient; ii) a differential amplifier that receives electrical signals from each electrode and process them to generate an analog ECG waveform; iii) an analog-to-digital converter that converts the analog ECG waveform into a digital ECG waveform; and iv) a transceiver that transmits a digital data stream representing the digital ECG waveform (or information calculated from the waveform) through the cable and to the processing system. Different ECG systems, typically featuring three, five, or twelve electrodes, can be interchanged with one another.

Abstract: The invention generally relates to systems and methods for precursor and neutral loss scan in an ion trap. In certain aspects, the invention provides a system that includes a mass spectrometer having an ion trap, and a central processing unit (CPU). The CPU includes storage coupled to the CPU for storing instructions that when executed by the CPU cause the system to excite a precursor ion and eject a product ion in the single ion trap.

Abstract: A thermal control unit supplies temperature controlled fluid to a patient to control the patient's temperature. The thermal control unit includes a fluid outlet, fluid inlet, heat exchanger, pump, patient temperature probe port, user interface, and controller. The controller receives patient temperature readings from the patient temperature probe port and controls a temperature of the circulating fluid in a first manner when no event data is received regarding treatment of the patient. The controller controls a temperature of the circulating fluid in a second and different manner when event data is received. The event data may relate to medication and/or fluid administered to the patient. The different manners include determining a target fluid temperature in using different inputs and/or alarming in different manners. In some cases, the controller pauses the use of the patient temperature readings while continuing to deliver temperature controlled fluid to the patient.

Abstract: The present invention relates generally to the generation of bio-products from organic matter feedstocks. More specifically, the present invention relates to improved methods for the hydrothermal/thermochemical conversion of lignocellulosic and/or fossilised organic feedstocks into biofuels (e.g. bio-oils) and/or chemical products (e.g. platform chemicals).

Abstract: An insertion device for an IUD. The insertion device comprises an introducer having an elongate hollow body and a first end and a second end, the hollow body defining an elongate passageway extending from the first end to the second end and defining openings at the first end and the second end, and a pusher provided or configured to be provided inside the elongate passageway such that the pusher is movable through or along the passageway. The passageway is sized to accommodate an IUD such that the IUD is slidable along the passageway. Further, the second end of the introducer that abuts the fundus of the uterus in use is configured to have an increased surface area relative to prior art devices so as to reduce the risk of injury, including perforation of the uterus.

Abstract: A method and system are provided for interfacing entities engaged in property exchange activities.

Abstract: Methods of calibration are provided. A method comprises introducing a material with cell-like properties and a known mass into a sensor on a measurement instrument to generate a calibration reading and adjusting an output module of the measurement instrument until the measurement instrument calibrates to the known mass for the material.

Abstract: Computer-implemented systems and methods for automated diagnosis of diabetic retinopathy apply machine learning techniques to clinical and demographic data combined with optical coherence tomography and optical coherence tomography angiography image data to diagnose and grade diabetic retinopathy.

Abstract: A submersible water desalination apparatus includes an array of generally parallel water separation membrane cartridges each having a water separation membrane, an impermeable cartridge wall surrounding the membrane, and a product water collection tube that collects from inside the cartridges at least partially desalinated product water passing through the membrane, and through which the at least partially desalinated water exits the cartridges and enters a product water collection manifold. The cartridges are mounted in a perforated divider plate. In embodiments, a) the manifold is adhesively bonded to a plurality of the collection tubes, orb) the divider plate is adhesively bonded to a plurality of the cartridge walls or ends, or both a) and b). The adhesive reduces the likelihood of leakage at the manifold or divider plate.

Abstract: A method for controlling an amount of power delivered to an electrical load may include controlling an average magnitude of a load current towards a target load current that ranges from a maximum-rated current to a minimum-rated current in a normal mode, and controlling the average magnitude of the load current below the minimum-rated current in a burst mode. The burst mode may include at least one burst-mode period that comprises a first time period associated with an active state and a second time period associated with an inactive state. During the burst mode, the method may include regulating a peak magnitude of the load current towards the minimum-rated current during the active state, and stopping the generation of at least one drive signal during the inactive state to control the average magnitude of the load current to be less than the minimum-rated current.