Abstract: The present invention generally relates to nanoscale wires, including anisotropic deposition in nanoscale wires. In one set of embodiments, material may be deposited on certain portions of a nanoscale wire, e.g., anisotropically. For example, material may be deposited on a first facet of a crystalline nanoscale wire but not on a second facet. In some cases, additional materials may be deposited thereon, and/or the portions of the nanoscale wire may be removed, e.g., to produce vacant regions within the nanoscale wire, which may contain gas or other species. Other embodiments of the invention may be directed to articles made thereby, devices containing such nanoscale wires, kits involving such nanoscale wires, or the like.

Abstract: Methods of treating, managing or preventing psoriatic arthritis are disclosed. Specific methods encompass the administration of apremilast, alone or in combination with a second active agent.

Abstract: The present invention generally relates to nanoscale wires and, in particular, to nanoscale wires with heterojunctions, such as tip-localized homo- or heterojunctions. In one aspect, the nanoscale wire may include a core, an inner shell surrounding the core, and an outer shell surrounding the inner shell. The outer shell may also contact the core, e.g., at an end portion of the nanoscale wire. In some cases, such nanoscale wires may be used as electrical devices. For example a p-n junction may be created where the inner shell is electrically insulating, and the core and the outer shell are p-doped and n-doped. Other aspects of the present invention generally relate to methods of making or using such nanoscale wires, devices, or kits including such nanoscale wires, or the like.

Abstract: It is provided PACE4 inhibitors and their uses for treating infection, cancer. Particularly, it is provided a method or use for the treatment of a cancer in a subject, comprising administering to the subject a therapeutically effective amount of the PACE4 inhibitors or the composition disclosed.

Abstract: The present disclosure concerns a method and detector (10) for detecting an analyte (1) in a sample volume (2), such as nitrosamine in an amine solvent. The method comprises measuring a resonance Raman spectrum (I1) with a first light beam (PI) matching an electronic transition of the analyte (1). The detection of the analyte is enhanced by measuring an off-resonance Raman spectrum (12) using a second light beam (P2) that is shifted in wavelength at least 10 nm away from the electronic resonance. The resonance Raman signal (S1) of the analyte (1) is isolated from the background (Q1, Q2) by a difference analysis between the resonance and off-resonance Raman spectra (I1, I2). The method and detector (10) can be employed for detecting nitrosamine in a carbon capture process or plant (20) that employs an amine solvent.

Abstract: A spherically mounted retroreflector (SMR) includes a substrate, an optic, and an adhesive. The substrate has a partially spherical outer surface and a cavity, the partially spherical outer surface has a sphere center. The optic has a cube-corner retroreflector fixedly disposed within the cavity; the cube-corner retroreflector has an optical vertex. The adhesive is disposed between the optic and the substrate and fixedly adheres the optic to the substrate. The optical vertex is coincident with the sphere center. The substrate is made from a ferromagnetic material and has an electroless nickel outer coating.

Abstract: The present invention generally relates to nanoscale wires, and to systems and methods of producing nanoscale wires. In some aspects, the present invention is generally related to facet-specific deposition on semiconductor surfaces. In one embodiment, a first surface of a nanoscale wire, or a semiconductor, is preferentially oxidized relative to a second surface, and material is preferentially deposited on the second surface relative to the first surface. For example, the nanoscale wire or semiconductor may be a silicon nanowire that is initially exposed to an etchant to remove silicon oxide, then exposed to an oxidant under conditions such that one facet or surface (e.g., a {113} facet) is oxidized more quickly than another facet or surface (e.g., a {111} facet). Material may then be deposited or immobilized on the less-oxidized facet relative to the more-oxidized facet.

Abstract: A spherically mounted retroreflector (SMR) includes a replicated optic, a substrate, and an adhesive. The replicated optic, which includes a cube-corner retroreflector, has a base area smaller than the retroreflector area. The substrate has a partially spherical outer surface and a cavity sized to accept the replicated optic. An adhesive attaches the optic to the substrate.

Abstract: Embodiments of the present invention provide methods for providing a non-registering endpoint with non-registration services (such as the ability to make a call) in an IMS network without requiring the non-registering endpoint to register. A request for a non-registration service is received and processed by an entity in the IMS network that is configured to handle such requests. The entity requires information about the non-registering endpoint itself before it can process the request. Since the non-registering endpoint is part of the network, a Home Subscriber Server (HSS) knows some information about the non-registering endpoint, but can only provide this information to the entity if the non-registering endpoint is registered or being registered by the entity. Consequently, in embodiments, the entity makes it look like the non-registering endpoint is registering, in order for the entity to obtain the information from the HSS.

Abstract: The present invention generally relates to nanoscale wires, and to methods of producing nanoscale wires. In some aspects, the nanoscale wires are nanowires comprising a core which is continuous and a shell which may be continuous or discontinuous, and/or may have regions having different cross-sectional areas. In some embodiments, the shell regions are produced by passing the shell material (or a precursor thereof) over a core nanoscale wire under conditions in which Plateau-Raleigh crystal growth occurs, which can lead to non-homogenous deposition of the shell material on different regions of the core. The core and the shell each independently may comprise semiconductors, and/or non-semiconductor materials such as semiconductor oxides, metals, polymers, or the like. Other embodiments are generally directed to systems and methods of making or using such nanoscale wires, devices containing such nanoscale wires, or the like.

Abstract: Disclosed herein are PACE4 inhibitors, compositions comprising PACE4 inhibitors and their uses thereof for lowering PACE4 activity, reducing cell proliferation, reducing tumor growth, reducing metastasis formation, preventing and/or treating cancer. Also provided are methods for lowering PACE4 activity, reducing the proliferation of a cell, reducing tumor growth and/or treating and preventing cancer. Methods for screening PACE4 inhibitors and cell proliferation inhibitors are further provided.

Abstract: Embodiments of radiant barriers for vehicles are disclosed. According to one embodiment, a vehicle includes an interior cabin at least partially enclosed by a roof panel, a floor panel, and an engine compartment firewall, and a radiant barrier positioned within the interior cabin. The radiant barrier includes a first thermally reflective surface and a second thermally reflective surface opposite the first thermally reflective surface and separated from the first thermally reflective surface by a thickness t. The thickness t is constant along a length and a width of the radiant barrier. The radiant barrier at least partially thermally isolates the interior cabin from an external environment.

Abstract: A spherically mounted retroreflector (SMR) includes a replicated optic, a substrate, and an adhesive. The replicated optic, which includes a cube-corner retroreflector, has a base area smaller than the retroreflector area. The substrate has a partially spherical outer surface and a cavity sized to accept the replicated optic. An adhesive attaches the optic to the substrate.

Abstract: Embodiments of radiant barriers for vehicles are disclosed. According to one embodiment, a vehicle includes an interior cabin at least partially enclosed by a roof panel, a floor panel, and an engine compartment firewall, and a radiant barrier positioned within the interior cabin. The radiant barrier includes a first thermally reflective surface and a second thermally reflective surface opposite the first thermally reflective surface and separated from the first thermally reflective surface by a thickness t. The thickness t is constant along a length and a width of the radiant barrier. The radiant barrier at least partially thermally isolates the interior cabin from an external environment.

Abstract: The present disclosure concerns a monolithic spectrometer (1) for spectrally resolving light (R). The spectrometer (1) comprises a body (2) of solid material having optical surfaces (3, 4, 5, 6, 8) arranged to guide the light (R) along an optical path (E1, E2, E3, E4) inside the body (2). A collimating surface (4) and focusing surface (6) are part of a single surface having a continuous optically functional shape. The surfaces (3,4,5,6,8) of the body (2) are arranged to have a third or fourth part (E3, E4) of the optical path between a grating surface (5) and an exit surface (8) cross (C) with a first part (E1) of the optical path between an entry surface (3) and a collimating surface (4).

Abstract: The present disclosure concerns a measuring probe (10) for non-invasive in vivo measurement of blood analytes (33) by Raman spectroscopy. The measuring probe (10) comprises a housing (20) having a skin engaging surface (21). The housing (20) comprises a first optical system (1, 3, 4) arranged for providing source light (11) to the skin engaging surface (21) for penetrating a subject's skin (31) by said source light (11) for interacting with the blood analytes (33). The housing (20) further comprises a second optical system (5, 6, 2) arranged for capturing scattered Raman light (12) from the blood analytes (33) for measurement of the blood analytes (33). The first optical system (1, 3, 4) is arranged for providing the source light (11) as a collimated beam (1c) onto the skin (31).

Abstract: Embodiments of radiant barriers for vehicles are disclosed. According to one embodiment, a vehicle includes an interior cabin at least partially enclosed by a roof panel, a floor panel, and an engine compartment firewall, and a radiant barrier positioned within the interior cabin. The radiant barrier includes a first thermally reflective surface and a second thermally reflective surface opposite the first thermally reflective surface and separated from the first thermally reflective surface by a thickness t. The thickness t is constant along a length and a width of the radiant barrier. The radiant barrier at least partially thermally isolates the interior cabin from an external environment.

Abstract: A spherically mounted retroreflector (SMR) includes a substrate, an optic, and an adhesive. The substrate has a partially spherical outer surface and a cavity, the partially spherical outer surface has a sphere center. The optic has a cube-corner retroreflector fixedly disposed within the cavity; the cube-corner retroreflector has an optical vertex. The adhesive is disposed between the optic and the substrate and fixedly adheres the optic to the substrate. The optical vertex is coincident with the sphere center. The substrate is made from a ferromagnetic material and has an electroless nickel outer coating.

Abstract: Vehicles including collapsible cargo containers that collapse beneath tumble seats and methods of collapsing collapsible cargo containers beneath tumble seats are disclosed. A vehicle includes a vehicle floor, a tumble seat pivotably coupled to the vehicle floor, and a collapsible cargo container attached to the vehicle floor and attached to the tumble seat. The tumble seat is pivotable from a tumble-forward position to an upright seating position. When the tumble seat is pivoted from the tumble-forward position to the upright seating position, the collapsible cargo container collapses from a cargo storage configuration to a collapsed configuration beneath the tumble seat.

Abstract: A pump includes a pump casing that defines a pump chamber, the pump casing having an inlet and an outlet. An impeller is arranged with respect to the pump chamber to displace fluid from the inlet into the pump chamber. A vortex shaping mechanism is arranged in the pump chamber and is configured to constrain fluid within the pump chamber into a rotational flow pattern about a rotational axis. At least the casing and the vortex shaping mechanism are configured so that a portion of the fluid is encouraged to establish a solid body vortex, with an outer periphery of the solid body vortex being determined by the vortex shaping mechanism, and a portion of the fluid defining a diffusion zone in fluid communication with the outlet such that fluid can diffuse across a fluid interface between the solid body vortex and the diffusion zone to generate a pumping pressure at the outlet.