Abstract: A sterile drape, a surgical system with the drape, and a draping method are provided. In one embodiment, a sterile drape includes a plurality of drape pockets, each of the drape pockets including an exterior surface to be adjacent a sterile field for performing a surgical procedure and an interior surface to be adjacent a non-sterile instrument manipulator coupled to a manipulator arm of a robotic surgical system. The drape further includes a plurality of flexible membranes at a distal face of each of the drape pockets for interfacing between outputs of an instrument manipulator and inputs of a respective surgical instrument, and a rotatable seal adapted to couple a proximal opening of each of the drape pockets to a rotatable element at a distal end of the manipulator arm.

Abstract: Robotic surgical systems and methods of coupling a surgical instrument to a manipulator arm are provided. In one embodiment, a system includes a base; a setup link operably coupled to the base, the setup link locating a remote center of motion for the robotic surgical system; a proximal link operably coupled to the setup link; and a distal link operably coupled to the proximal link. A plurality of instrument manipulators are rotatably coupled to a distal end of the distal link, each of the instrument manipulators including a plurality of actuator outputs distally protruding from a distal end of a frame.

Abstract: An entry guide tube and cannula assembly, a surgical system including the assembly, and a method of surgical instrument insertion are provided. In one embodiment, the assembly includes a cannula having a proximal portion that operably couples to an accessory clamp of a manipulator arm, and a distal tubular member coupled to the proximal portion, the tubular member having an opening for passage of at least one instrument shaft. The assembly also includes an entry guide tube rotatably coupled to the proximal portion of the cannula, the entry guide tube including a plurality of channels for passage of a plurality of instrument shafts, wherein the entry guide tube is rotatably driven relative to the proximal portion of the cannula by rotation of at least one instrument shaft about a longitudinal axis of the entry guide tube.

Abstract: An entry guide tube and cannula assembly, a surgical system including the assembly, and a method of surgical instrument insertion are provided. In one embodiment, the assembly includes a cannula having a proximal portion that operably couples to an accessory clamp of a manipulator arm, and a distal tubular member coupled to the proximal portion, the tubular member having an opening for passage of at least one instrument shaft. The assembly also includes an entry guide tube rotatably coupled to the proximal portion of the cannula, the entry guide tube including a plurality of channels for passage of a plurality of instrument shafts, wherein the entry guide tube is rotatably driven relative to the proximal portion of the cannula by rotation of at least one instrument shaft about a longitudinal axis of the entry guide tube.

Abstract: In a graphics processing system, a command list reader first reads-in and identifies a portion of a command list. The primitives corresponding to the commands in the portion of the command list are then subjected to a Z-only processing pass. This allows a Z-buffer 16 and a hierarchical Z-pyramid 8 to be filled with the appropriate Z-values for the primitives in the portion of the primitive list. The primitives are then subjected to a second, normal rendering, processing pass, but the filled Z-buffer 16 and Z-pyramid from the first processing pass are used together with the Z-tests 7, 10 performed in the second processing pass to determine which primitive should be processed for each sampling point in the second processing pass.

Abstract: In selected embodiments, improved image restoration is realized using extensions of Wiener filtering combined with multiple image captures acquired after simple, fast reconfigurations of an optical imaging system. These reconfigurations may yield distinct OTF responses for each capture. The optical imaging system may reduce fabrication cost, power consumption, and/or system weight/volume by correcting significant optical aberrations. The system may be configured to perform independent correction of fields within the total field-of-regard. The system may also be configured to perform independent correction of different spectral bands.

Abstract: Provided are novel compositions and analogs which are useful in a number of applications, indications and diseases, as well as for monitoring pharmakinetics and patient management. These compounds and analogs are applicable to treating tumors of the central nervous system, e.g., glioblastoma (GBM).

Abstract: Configurations are described for conducting minimally invasive medical interventions utilizing elongate instruments and assemblies thereof to stabilize and/or fixate a sacro-iliac joint. In one embodiment, a tool assembly may be advanced from a posterior approach into the SI junction and configured to create a defect defined at least in part by portions of both the sacrum and the ilium, the defect having a three dimensional shape defined in part by at least one noncircular cross sectional shape in a plane substantially perpendicular to the longitudinal axis of the tool assembly. After a defect is created, the tool assembly may be retracted and a prosthesis deployed into the defect.

Abstract: A reactive distillation method comprises introducing an feed stream comprising ethanol to a reactive distillation column, contacting the feed stream with a catalyst in the reactive distillation column during a distillation, where the feed stream reacts in the presence of the catalyst to produce a reaction product comprising ethyl acetate and hydrogen, removing ethyl acetate during the distillation from the reactive distillation column as a bottoms stream, and removing hydrogen during the distillation from the reactive distillation column as an overhead stream.

Abstract: Customization features for providing users with the ability to customize various aspects of a vehicle management system are described. These customization features can include functionality for generating custom reports based on vehicle parameters, including diagnostic codes. The customization features can also include features for customizing alerts based on vehicle parameters and features for customizing nomenclature in the vehicle management system.

Abstract: Provided are novel compositions and analogs which are useful in a number of applications, indications and diseases, as well as for monitoring pharmakinetics and patient management. These compounds and analogs are applicable to treating tumors of the central nervous system, e.g., glioblastoma (GBM).

Abstract: Provided are novel compositions and analogs which are useful in a number of applications, indications and diseases, as well as for monitoring pharmakinetics and patient management. These compounds and analogs are applicable to treating tumors of the central nervous system, e.g., glioblastoma (GBM).

Abstract: Provided is a derivative of 22-hydroxycholesterol, 24S-hydroxycholesterol, 25-hydroxycholesterol, 26-hydroxycholesterol or 27-hydroxycholesterol. Also provided is a protein conjugated to the above derivative. Further provided is an antibody composition comprising antibodies that specifically bind to 22-hydroxycholesterol, 24S-hydroxycholesterol, 25-hydroxycholesterol, 26-hydroxycholesterol or 27-hydroxycholesterol. Additionally, a method of making antibodies that specifically bind to 22-hydroxycholesterol, 24S-hydroxycholesterol, 25-hydroxycholesterol, 26-hydroxycholesterol or 27-hydroxycholesterol is provided. Also, a method of assaying for 22-hydroxycholesterol, 24S-hydroxycholesterol, 25-hydroxycholesterol, 26-hydroxycholesterol or 27-hydroxycholesterol is provided. Additionally provided is a kit for detecting 22-hydroxycholesterol, 24S-hydroxycholesterol, 25-hydroxycholesterol, 26-hydroxycholesterol or 27-hydroxycholesterol.

Abstract: Embodiments are described for closing vascular access ports, such as arteriotomies, which involve placement and deployment of an expandable device configured to prevent blood flow across a subject arteriotomy while also keeping disturbance of intravascular flow to a minimum. Suitable prostheses may comprise one or more frames constructed from lengths of flexible materials, such as shape memory alloys or polymers. Such frames may be coupled to sheetlike or tube-like structures configured to spread loads, minimize thrombosis which may be related to intravascular flow, and maintain hemostasis.

Abstract: Embodiments are described for closing vascular access ports, such as arteriotomies, which involve placement and deployment of an expandable device configured to prevent blood flow across a subject arteriotomy while also keeping disturbance of intravascular flow to a minimum. Suitable prostheses may comprise one or more frames constructed from lengths of flexible materials, such as shape memory alloys or polymers. Such frames may be coupled to sheetlike or tube-like structures configured to spread loads, minimize thrombosis which may be related to intravascular flow, and maintain hemostasis.

Abstract: Embodiments include methods, apparatus, and systems for storage device data encryption. One method includes encrypting data on a storage device with a key and then transmitting the key to a cryptographic module that encrypts the key to form a Binary Large Object (BLOB). The BLOB is transmitted to an array controller that is coupled to the storage device which stores the BLOB.

Abstract: Provided are novel compositions and analogs which are useful in a number of applications, indications and diseases, as well as for monitoring pharmakinetics and patient management. These compounds and analogs are applicable to treating tumors of the central nervous system, e.g., glioblastoma (GBM).

Abstract: Provided are novel compositions which uniquely inhibit sphingosine kinase Type 1 (SphK1) and which are useful in a number of applications including killing or damaging cancer cells, inducing apoptosis, inhibiting growth, metastasis and development of chemoresistance in cancer cells, leukemia, increasing the effectiveness of anti-cancer agents, attenuating immune reactivity, inhibiting survival signaling in cancer cells, and reducing symptoms of multiple sclerosis.

Abstract: In a graphics processing system, a command list reader 3 first reads-in and identifies a portion of a command list. The primitives corresponding to the commands in the portion of the command list are then subjected to a Z-only processing pass. This allows a Z-buffer 16 and a hierarchical Z-pyramid 8 to be filled with the appropriate Z-values for the primitives in the portion of the primitive list. The primitives are then subjected to a second, normal rendering, processing pass, but the filled Z-buffer 16 and Z-pyramid 8 from the first processing pass are used together with the Z-tests 7, 10 performed in the second processing pass to determine which primitive should be processed for each sampling point in the second processing pass.

Abstract: A measuring gauge constructed of a transparent “L” shaped body having an elongated first arm and a second shorter arm disposed at 90 degrees to the first arm and defining a notch therein which forms a triangle with the first leg of the triangle angularly disposed with respect to the outer edge of the second arm. A plurality of indicia are carried by the two legs of the gauge. The indicia each include a center band sandwiched between outer bands with the inner and outer bands being of contrasting colors. The side edges of the gauge are inserted between the flaps and back panels of the envelope into engagement with a gum line and a depth of penetration is observed by determining the intersection of an edge of the envelope with the indicium along a side edge of the gauge thereby determining whether or not the envelope is in or out of specification.