Patents by Inventor Robert Graham

Robert Graham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11444837
    Abstract: Techniques are disclosed for network policy verification system that can obtain a set of connectivity paths of a containerized environment that individually indicate connections between pairs of containers. Identify a first container and a second container of a pair based at least in part on a connectivity path. Determine a network policy corresponding to the connectivity path that indicates an expected result of that particular connection. A connection can be initiated between the two containers. The result may be presented at a user device based at least in part on identifying that the result is different from the expected result indicated by the network policy corresponding to the connectivity path.
    Type: Grant
    Filed: February 26, 2021
    Date of Patent: September 13, 2022
    Assignee: Oracle International Corporation
    Inventors: Olgierd Stanislaw Pieczul, Subaru Arthur Ueno, Robert Graham Clark
  • Publication number: 20220278900
    Abstract: Techniques are disclosed for network policy verification system that can obtain a set of connectivity paths of a containerized environment that individually indicate connections between pairs of containers. Identify a first container and a second container of a pair based at least in part on a connectivity path. Determine a network policy corresponding to the connectivity path that indicates an expected result of that particular connection. A connection can be initiated between the two containers. The result may be presented at a user device based at least in part on identifying that the result is different from the expected result indicated by the network policy corresponding to the connectivity path.
    Type: Application
    Filed: February 26, 2021
    Publication date: September 1, 2022
    Applicant: Oracle International Corporation
    Inventors: Olgierd Stanislaw Pieczul, Subaru Arthur Ueno, Robert Graham Clark
  • Publication number: 20220277948
    Abstract: The invention generally relates to systems and methods for conducting reactions and screening for reaction products.
    Type: Application
    Filed: May 16, 2022
    Publication date: September 1, 2022
    Inventor: Robert Graham Cooks
  • Publication number: 20220265172
    Abstract: The invention generally relates to enclosed desorption electrospray ionization probes, systems, and methods. In certain embodiments, the invention provides a source of DESI-active spray, in which a distal portion of the source is enclosed within a transfer member such that the DESI-active spray is produced within the transfer member.
    Type: Application
    Filed: March 11, 2022
    Publication date: August 25, 2022
    Inventors: Robert Graham Cooks, Zheng Ouyang, Chien-hsun Chen, Ziqing Lin, Livia Schiavinato Eberlin
  • Publication number: 20220263835
    Abstract: A computer system may receive one or more requests for access to one or more cloud services and may store the one or more requests in a request log. The computer system may receive one or more access rules applicable to cloud service access rights. The computer system may aggregate the one or more requests of the request log to determine access requirements for a container, the container being configured to store one or more applications. The computer system may generate and store container access policies that define access of a container and the one or more cloud services, the container access policies based at least in part on the aggregated one or more requests and the one or more access rules. The computer system may send the container access policies to a request forwarder of a compute instance in a production environment.
    Type: Application
    Filed: February 16, 2021
    Publication date: August 18, 2022
    Applicant: Oracle International Corporation
    Inventors: Olgierd Stanislaw Pieczul, Hubert Alexander Foskett, Robert Graham Clark
  • Publication number: 20220254620
    Abstract: The invention generally relates to systems and methods for precursor and neutral loss scan in an ion trap. In certain aspects, the invention provides a system that includes a mass spectrometer having an ion trap, and a central processing unit (CPU). The CPU includes storage coupled to the CPU for storing instructions that when executed by the CPU cause the system to excite a precursor ion and eject a product ion in the single ion trap.
    Type: Application
    Filed: April 27, 2022
    Publication date: August 11, 2022
    Inventors: Robert Graham Cooks, Dalton Snyder, Christopher Pulliam
  • Publication number: 20220247639
    Abstract: Techniques are disclosed for query processing system that can, when queried, generate a result related to one or more connectivity paths and/or one or more network security rules. Network security rules and connectivity paths may be stored in corresponding data structures (e.g., sets of attributes) that may be utilized with a number of set operations. The user may issue a query requesting the system to apply a rule to a path, a set of rules to a set of paths, to identify if one set of rule(s) are equivalent to another set of rule(s), and the like. Utilizing this query processing system can enable a user to identify effects of one or more network rules with respect to traffic being allowed or restricted along particular connectivity paths between components of the system.
    Type: Application
    Filed: July 19, 2021
    Publication date: August 4, 2022
    Applicant: Oracle International Corporation
    Inventors: Olgierd Stanislaw Pieczul, Robert Graham Clark
  • Patent number: 11397189
    Abstract: The invention generally relates to methods for analyzing a metabolite level in a sample. In certain embodiments, methods of the invention may involve obtaining a sample, analyzing the sample using a mass spectrometry technique to determine a level of at least one metabolite in the sample, and correlating the metabolite level with an originating source of the sample, thereby analyzing the sample.
    Type: Grant
    Filed: January 17, 2017
    Date of Patent: July 26, 2022
    Assignee: Purdue Research Foundation
    Inventors: Robert Graham Cooks, Kevin Scott Kerian, Alan Keith Jarmusch, Ahmed Mohamed Hamid, Livia Schiavinato Eberlin
  • Patent number: 11397166
    Abstract: The invention generally relates to high-throughput label-free enzymatic bioassays using desorption electrospray ionization-mass spectrometry (DESI-MS).
    Type: Grant
    Filed: March 5, 2021
    Date of Patent: July 26, 2022
    Assignee: Purdue Research Foundation
    Inventors: Robert Graham Cooks, Nicolás M. Morato, Dylan T. Holden
  • Patent number: 11393668
    Abstract: The invention generally relates to methods for analyzing an analyte in a sample that involve providing a capture module, the module configured to capture an analyte from a sample in an ambient environment and generate ions of the analyte, wherein the capture module comprises a cartridge and a porous substrate within the cartridge that is connected to a voltage source; and generating ions of the analyte from the capture module that are analyzed in a mass analyzer operably coupled to the capture module, thereby analyzing the analyte in the sample.
    Type: Grant
    Filed: February 19, 2021
    Date of Patent: July 19, 2022
    Assignee: Purdue Research Foundation
    Inventors: Robert Graham Cooks, Ahmed Mohamed Hamid, Alan Keith Jarmusch, Zheng Ouyang
  • Publication number: 20220221442
    Abstract: The invention generally relates to a sample dispenser including an internal standard and methods of use thereof.
    Type: Application
    Filed: January 25, 2022
    Publication date: July 14, 2022
    Inventors: Zheng Ouyang, He Wang, Nicholas E. Manicke, Robert Graham Cooks, Qian Yang, Jiangjiang Liu
  • Publication number: 20220217139
    Abstract: A system and technique for a Request Forwarder as for a computer network architecture is disclosed to provide selective access to one or more cloud services. In some implementations, a computer system may receive a request for access to a cloud service, the request including a container credential. The computer system may determine an identification of the container using the container credential. The computer system may verify that the container requesting access to the cloud service is authorized based at least in part on stored policies. Based at least in part on the determination that the container requesting access to the cloud service is authorized: receiving instance credential from a metadata service. The computer system may include the instance credential with the request. The computer system may send the request to the cloud service. In various examples, the Request Forwarder can be provided as a service.
    Type: Application
    Filed: January 6, 2021
    Publication date: July 7, 2022
    Applicant: Oracle International Corporation
    Inventors: Olgierd Stanislaw Pieczul, Shrey Arora, Robert Graham Clark
  • Publication number: 20220216046
    Abstract: The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives the focused ions and a distal end of the outlet is open to ambient pressure.
    Type: Application
    Filed: January 14, 2021
    Publication date: July 7, 2022
    Inventors: Robert Graham Cooks, Zane Baird, Wen-Ping Peng
  • Patent number: 11380534
    Abstract: The invention generally relates to sample analysis systems and methods of use thereof. In certain aspects, the invention provides a system for analyzing a sample that includes an ion generator configured to generate ions from a sample. The system additionally includes an ion separator configured to separate at or above atmospheric pressure the ions received from the ion generator without use of laminar flowing gas, and a detector that receives and detects the separated ions.
    Type: Grant
    Filed: June 8, 2020
    Date of Patent: July 5, 2022
    Assignee: Purdue Research Foundation
    Inventors: Robert Graham Cooks, Zane Baird, Pu Wei
  • Publication number: 20220199383
    Abstract: The invention generally relates to systems and methods for on-line reaction monitoring. In certain embodiments, the invention provides systems that include a reaction vessel having an outlet, a quantitation unit coupled to the outlet and configured to introduce internal standard and solvent into reaction solution flowed from the reaction vessel, one or more ion generating devices that receive flow from the quantitation unit, and a mass spectrometer.
    Type: Application
    Filed: March 10, 2022
    Publication date: June 23, 2022
    Inventors: Robert Graham Cooks, Xin Yan, Christopher Pulliam, Ryan M. Bain, Tawnya Flick
  • Publication number: 20220199384
    Abstract: The invention generally relates to methods and devices for synchronization of ion generation with cycling of a discontinuous atmospheric interface. In certain embodiments, the invention provides a system for analyzing a sample that includes a mass spectrometry probe that generates sample ions, a discontinuous atmospheric interface, and a mass analyzer, in which the system is configured such that ion formation is synchronized with cycling of the discontinuous atmospheric interface.
    Type: Application
    Filed: July 16, 2020
    Publication date: June 23, 2022
    Inventors: Robert Graham Cooks, Guangtao Li, Guangming Huang, Jason Duncan, Xin Li, Ewa Sokol, Xin Yan
  • Publication number: 20220191248
    Abstract: Techniques are disclosed for generating network security policies for different versions of a component of an application deployed in a computing environment where the different versions have potentially different network requirements and the different versions operate together at the same time in the computing environment. The disclosed techniques include capabilities for enabling different versions of a component of a containerized application to co-exist at the same time on different computing nodes in a cluster of nodes in a containerized environment that deploys and executes the application. The techniques additionally include capabilities for enabling different network policies to be generated for the different versions of the component, where each component has potentially different network requirements. The techniques provide a mechanism to create precise, per-component network policies, while respecting the overall coarse-grained policies of the containerized application.
    Type: Application
    Filed: December 16, 2020
    Publication date: June 16, 2022
    Applicant: Oracle International Corporation
    Inventors: Olgierd Stanislaw Pieczul, Robert Graham Clark, Nitin Srinivasa Rao Jami
  • Patent number: 11361954
    Abstract: The invention generally relates to systems and methods for conducting reactions and screening for reaction products.
    Type: Grant
    Filed: March 22, 2018
    Date of Patent: June 14, 2022
    Assignee: Purdue Research Foundation
    Inventor: Robert Graham Cooks
  • Patent number: 11355328
    Abstract: The invention generally relates to systems and methods for isolating a target ion in an ion trap. In certain aspects, the invention provides a system that includes a mass spectrometer having an ion trap, and a central processing unit (CPU). The CPU includes storage coupled to the CPU for storing instructions that when executed by the CPU cause the system to apply a dual frequency waveform to the ion trap that ejects non-target ions from the ion trap while retaining a target ion in the ion trap.
    Type: Grant
    Filed: April 13, 2017
    Date of Patent: June 7, 2022
    Assignee: Purdue Research Foundation
    Inventors: Robert Graham Cooks, Dalton Snyder
  • Patent number: 11348778
    Abstract: The invention generally relates to systems and methods for precursor and neutral loss scan in an ion trap. In certain aspects, the invention provides a system that includes a mass spectrometer having an ion trap, and a central processing unit (CPU). The CPU includes storage coupled to the CPU for storing instructions that when executed by the CPU cause the system to excite a precursor ion and eject a product ion in the single ion trap.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: May 31, 2022
    Assignee: Purdue Research Foundation
    Inventors: Robert Graham Cooks, Dalton Snyder, Christopher Pulliam