Abstract: A method for controlling a dual fuel engine system includes determining a gas flow target for an internal combustion engine of the dual fuel engine system, where the gas flow target is based on a gas power target of the internal combustion engine, a thermal efficiency estimate of the internal combustion engine, and a lower heating value (LHV) within the internal combustion engine. The method also includes adjusting the gas flow target based on at least one of a measured gas temperature or a measured gas injector pressure and determining at least one base gas injector command based on the adjusted gas flow target, a gas substitution rate estimate, and a gas substitution rate target. The method further includes determining, based on the at least one base gas injector command, a gas injector command for at least one engine bank.

Abstract: Processes and methods for refining ferronickel alloy, and producing nickel sulfate or other nickel product, are provided, where the ferronickel alloy is treated with an oxidizing leach. The oxidizing leach may be, for example, a pressure oxidation (POX) leach or a leach with peroxide or copper (II) ions. The treatment may be in the presence of added copper, such as by providing a copper sulfate solution. Producing nickel sulfate may comprise removing copper and iron after the leach, removing impurities, and either crystallizing the nickel sulfate or precipitating/winning another nickel product.

Abstract: An automated teller machine comprises a communications module; an image module; a processor; and a memory coupled to the processor storing instructions that, when executed by the processor, configure the processor to receive a first cheque for deposit; engage the image module to capture an image of the first cheque; send, via the communications module and to a server computer system, a signal that includes the image of the first cheque for acceptance; send, via the communications module and to an automated teller machine switch, a signal that includes a request for transaction authorization approval based on the first cheque; receive, via the communications module and from the server computer system, a signal that includes an indication of acceptance of the image of the first cheque; receive, via the communications module and from the automated teller machine switch, a signal that includes an indication of approval of the request for the transaction authorization based on the first cheque; and responsive to r

Abstract: The invention relates to a method for a computer device, for detecting an optimal candidate compound based on a plurality of samples comprising a cell line and one or more biomarkers, and a plate map configuration, wherein the plate map configuration is providing locations of samples comprising cell lines exposed to one or more biomarkers and different concentrations of a candidate compound forming at least one concentration gradient, the candidate compound being comprised in a plurality of candidate compounds, said method comprising generating (310) phenotypic profiles of each concentration gradient of each of the plurality of candidate compounds at a plurality of successive points in time to form a plurality of compound profiles, wherein generating phenotypic profiles comprises the steps obtaining (312) image data depicting each sample comprised in the concentration gradient, generating (314) a class-label and a class for each cell of the samples based on the image data, detecting (320) the optimal candidat

Abstract: A heater device for an electronic cigarette includes: a heater unit arranged to vaporise a liquid received from a liquid reservoir to generate a vapour; and a vapour flow path extending from the heater unit arranged to fluidly communicate with a mouthpiece of an electronic cigarette to allow the generated vapour to flow from the heater unit to the mouthpiece. The heater unit includes a first heating portion and a second heating portion, and the first and second heating portions are integrally formed such that the first and second heating portions form a single heater unit.

Abstract: The present invention relates to peptide conjugates of cytotoxins such as topoisomerase I inhibitors which are useful for the treatment of diseases such as cancer.

Abstract: Security measures for signal paths with tree structures can be implemented at design phase using an EDA software program or tool with security feature functionality that, when executed by a computing system, directs the computing system to: display a canvas through which components of a circuit are arranged; and provide a menu of commands, including an option to add components from a library to the canvas and an option to secure a tree. In response to receiving a selection of the option to secure the tree, the system can be directed to add a hardware countermeasure coupled to at least two lines or terminal nodes of a tree structure identified from components on the canvas or in a netlist corresponding to a circuit's design.

Abstract: Disclosed are compounds of a formula provided herein that show efficacy in the inhibition of SOX18 protein activity, and in particular with respect to the ability of SOX18 to bind DNA and/or particular protein partners. Further, methods of treating angiogenesis- and/or lymphangiogenesis-related diseases, disorders or conditions, such as cancer metastasis and vascular cancers, are provided herein.

Abstract: A method and communication device for processing data for transmission from the communication device to a second communication device is provided. It is detected that the data comprises an attachment. An address of a copy of the attachment is determined, the attachment present on a storage device external to the communication devices. An address of the copy of the attachment is substituted in the data such that the copy is retrievable at the second communication device via the address. The data is then transmitted to the second communication device.

Abstract: A sheet-type aerosol generating article includes at least two aerosol generating sheets each having aerosol generating material and an inductively heatable susceptor The inductively heatable susceptor is positioned between the aerosol generating sheets and each of the aerosol generating sheets has an exposed surface. Methods for manufacturing sheet-type aerosol generating articles are also disclosed.

Abstract: A resistive flex microwave attenuator for coupling control signals to a quantum computational hardware system includes a set of planar transmission lines, each such planar transmission line having first and second ends along a longitudinal axis. Each such planar transmission line includes: a set of ground planes disposed in a direction parallel to the longitudinal axis; a dielectric disposed in a direction parallel to the longitudinal axis and in contact with the set of ground planes; a signal line disposed in a direction parallel to the longitudinal axis and in contact with the set of ground planes; a metallic layer disposed around the set of ground planes; an input, coupled to such planar transmission line at the first end, and configured to receive the control signals; and an output, coupled to such planar transmission line at the second end, and configured for coupling to the quantum computational hardware system.

Abstract: Rotary positive displacement machines can include a rotor having a teardrop-shaped profile that undergoes planetary motion relative to a stator having an elliptical or near-elliptical profile. In some embodiments, these rotary positive displacement machines can be used for a variety of applications including as positive displacement pumps. In some embodiments the rotor and stator are helical. In some embodiments the rotor comprises a dynamic seal. Aspects of the machine geometry can be selected to provide operational and/or durability benefits.

Abstract: A transducer includes a first piezoelectric layer; and a second piezoelectric layer that is above the first piezoelectric layer; wherein the second piezoelectric layer is a more compressive layer with an average stress that is less than or more compressive than an average stress of the first piezoelectric layer.

Abstract: A low noise piezoelectric sensor, such as a piezoelectric acoustic transducer, includes a first conductive layer, a second conductive layer, and a piezoelectric layer between the first conductive layer and the second conductive layer. The piezoelectric layer comprises aluminum scandium nitride (AlScN) having a scandium content of greater than 15%, in which the scandium content and an aluminum content comprises 100% of the aluminum scandium nitride. In this way, the piezoelectric layer (or the sensor including the piezoelectric layer) achieves a dissipation factor of less than about 0.1%.

Abstract: The present invention relates to peptide conjugates of peptidic tubulin inhibitors (e.g., monomethyl auristatins) which are useful for the treatment of diseases such as cancer.

Abstract: A combination chair and foldable side table, wherein the combination includes the chair, wherein the chair comprises at least a first leg and a second leg, at least a first member coupled to the first leg and a second member coupled to the second leg, wherein the first member includes a slot and/or the mounting of the first member on the first leg forms a slot between the first member and the first leg and wherein the second member includes a slot and/or the mounting of the second member on the second leg forms a slot between the second member and the second leg; and the foldable side table includes a first arm and a second arm, a first hand depending from the first arm and removably insertable into the slot associated with the first member, and a second hand depending from the second arm and removably insertable into the slot associated with the second member; a first cross-member assembly coupled intermediate the first and second arms and a second cross-member assembly coupled intermediate the first and sec

Abstract: In one aspect of the present disclosure, a movable barrier operator system is provided that includes a motor configured to turn a drum to pay out a cable from the drum and permit a door connected to the cable to move from an open position toward a closed position. The system includes a memory configured to store an expected variable of the door, and a sensor configured to detect movement of the door. The system further includes a processor circuit operatively coupled to the motor, the memory, and the sensor. The processor circuit is configured to: use the sensor to estimate an actual variable of the door; determine whether the actual variable is acceptable based at least in part on the expected variable and the processor circuit causing the motor to turn the drum; and change operation of the movable barrier upon the actual variable of the movable barrier being unacceptable.

Abstract: Apparatus for generating a supply of air at positive pressure for the amelioration or treatment of a respiratory disorder includes a first chamber, a second chamber, at least one inlet tube structured and configured to allow ambient air to enter the first chamber, at least one flow tube structured and configured to allow air to pass from the first chamber to the second chamber, and a blower structured and configured to produce a flow of air at positive pressure. The blower is positioned in the first chamber and structured and configured to receive air from the second chamber. The blower includes a housing structured and configured to sealingly separate air flow through an interior of the housing from the first chamber. The at least one inlet tube is axially spaced from the at least one flow tube.

Abstract: The disclosure relates to the system comprising a combination of a primary bioreactor with a secondary bioreactor to convert a gaseous stream comprising CO and optionally H2, or CO2 and H2 to at least one target product. Bioreactors may be any combination of aerobic and anaerobic, batch and continuous. The bioreactors comprise fermenting microorganisms that may typically be bacterial or fungal.

Abstract: An interface between cryogenic computational hardware and room temperature computational hardware includes a plurality of discrete stages, including a first stage at room temperature and a last stage at a cryogenic temperature. Each successive stage is configured for operation at a corresponding refrigeration temperature that is lower than the refrigeration temperature of each preceding stage and includes a set of planar transmission lines. The transmission lines of any given stage other than the first stage are proximally coupled to and contiguous with the transmission lines of an immediately preceding stage. The transmission lines of the first stage are proximally coupled to the room temperature computational hardware, and the transmission lines of the last stage are proximally coupled to the cryogenic computational hardware. Each stage has shielding configured to block electromagnetic radiation external to such stage.