Abstract: The present invention relates to polypeptides that block BLyS signaling, nucleic acid molecules encoding the polypeptides, and compositions comprising the polypeptides. The present invention also relates to methods for treating an immune-related disease or cancer using the polypeptides and compositions of the invention. The present invention also relates to methods for identifying inhibitors of BLyS signaling.

Abstract: A method for purifying a suspension containing colloid-seeded nanoparticles and excess colloids is provided that includes adding to the suspension a filter aid comprising a salt. The method further includes filtering the suspension with a filter of a pore size intermediate between the average colloid-seeded nanoparticle size and the average excess colloid size, so as to form a retentate that includes the majority of the colloid-seeded nanoparticles and a filtrate that includes the majority of the excess colloids. Still further, the method includes collecting the retentate. The method may be incorporated into a method of making metallized nanoparticles, such as nanoshells, by reduction of metal ions onto the purified colloid-seed nanoparticles so as to form the metallized nanoparticles.

Abstract: This invention pertains to a multi-panel or sectional door having a specially designed edge profile that coordinates between the panels in such a way as to prevent any items from being pinched between the door sections while the panels are moving. The door additionally contains exterior trim pieces that are designed to open and close cooperatively with the door sections, and avoid any gaps forming during operation. Finally, the door may contain optional side shields to the trim pieces, said shields designed to avoid side gaps between the trim and the door during operation.

Abstract: Methods and apparatus for providing nanoparticles having reduced symmetry are disclosed. One embodiment of a preferred method for producing such nanoparticles includes functionalization of a nanoparticle core, partial chemical passivation or masking of the nanoparticle surface, and nucleation and deposition of colloidal particles to selectively coat a specific section of the nanostructure surface with a conducting material.

Abstract: A method for purifying a suspension containing colloid-seeded nanoparticles and excess colloids is provided that includes adding to the suspension a filter aid comprising a salt. The method further includes filtering the suspension with a filter of a pore size intermediate between the average colloid-seeded nanoparticle size and the average excess colloid size, so as to form a retentate that includes the majority of the colloid-seeded nanoparticles and a filtrate that includes the majority of the excess colloids. Still further, the method includes collecting the retentate. The method may be incorporated into a method of making metallized nanoparticles, such as nanoshells, by reduction of metal ions onto the purified colloid-seed nanoparticles so as to form the metallized nanoparticles.

Abstract: A catheter has an electrode tip assembly that is bendable at the selection of the user in two different directions. The electrode tip assembly assumes different asymmetric predetermined curve configurations when bent in the two directions and is manipulated by means of steering wires adjustably connected tangentially to the lateral edges of a rotatable cam located in the catheter handle.

Abstract: A blisk includes a disk having a rim. A row of blades extends outwardly from the rib in a unitary construction. The blades are spaced apart in the disk rim to define fluted inner flowpath channels extending axially between the blades to bound corresponding flow passages therebetween.

Abstract: A blisk includes a disk having a rim. A row of blades extends outwardly from the rib in a unitary construction. The blades are spaced apart in the disk rim to define fluted inner flowpath channels extending axially between the blades to bound corresponding flow passages therebetween.

Abstract: A catheter has an electrode tip assembly that is bendable at the selection of the user in two different directions. The electrode tip assembly assumes different asymmetric predetermined curve configurations when bent in the two directions and is manipulated by means of steering wires adjustably connected tangentially to the lateral edges of a rotatable cam located in the catheter handle.

Abstract: A catheter has an electrode tip assembly that is bendable at the selection of the user in two different directions. The electrode tip assembly assumes different asymmetric predetermined curve configurations when bent in the two directions and is manipulated by means of steering wires adjustably connected tangentially to the lateral edges of a rotatable cam located in the catheter handle.