Abstract: Compounds of formula (I) that are capable of acting as purine receptor antagonists, pharmaceutical compositions including the compounds, and methods of making the compounds, are disclosed. The compounds and compositions can be used in treating or preventing disorders related to purine receptor hyperfunctioning.

Abstract: A method of addressing at least one qubit to be addressed in a set of two or more qubits includes exposing the qubit to be addressed to an electromagnetic field; and at a same time exposing another qubit of the set of two or more qubits to an electromagnetic counter field in such a way that the electromagnetic field has no effect on the other qubit or that the electromagnetic field has a different effect on the other qubit than on the qubit to be addressed. A device for performing the method includes the set of two or more qubits and electromagnetic sources for generating the electromagnetic field and electromagnetic counter field.

Abstract: A frac sand separator system includes a sand separator having an inlet fluidly connected to a well for receiving a fracking return mixture from the well. The sand separator is configured to separate water of the fracking return mixture from particulate matter of the fracking return mixture. The sand separator includes an outlet. The frac sand separator system includes a collection container fluidly connected to the outlet of the sand separator for receiving the particulate matter from the sand separator. At least one outlet valve is fluidly connected between the outlet of the sand separator and the collection container. The frac sand separator system includes a computing device operatively connected to the at least one outlet valve. The computing device includes a processor configured to automatically open the at least one outlet valve such that the particulate matter is released from the sand separator into the collection container.

Abstract: A device for generating and controlling a magnetic field strength and a method for generating and controlling a magnetic field strength are disclosed. The generation is very stable and precise. Preferably, reference values of physical variable can be generated relatively simply and economically. In addition, magnetic flux densities can be measured with high resolution and, in particular, highly robustly. The device and the method can also be used for transmitting information, in particular for ultra-wide band communication. The required devices can be very small, in particular miniature, and mobile.

Abstract: The invention provides a compound of formula (I): or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.

Abstract: Methods for treating or preventing a cognitive impairment in a subject in need of treatment thereof, the method comprising administering to the subject a therapeutically effective amount of an agent that enhances the NO-cGMP-PKG pathway are disclosed.

Abstract: The invention provides a compound of formula (I): or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.

Abstract: The present invention relates to benzimidazole ethers and related compounds which are of use in the field of agriculture as fungicides.

Abstract: The present invention relates to 2-thiobenzimidazoles of formula (I) which are of use as fungicides.

Abstract: A device for generating and controlling a magnetic field strength and a method for generating and controlling a magnetic field strength are disclosed. The generation is very stable and precise. Preferably, reference values of physical variable can be generated relatively simply and economically. In addition, magnetic flux densities can be measured with high resolution and, in particular, highly robustly. The device and the method can also be used for transmitting information, in particular for ultra-wide band communication. The required devices can be very small, in particular miniature, and mobile.

Abstract: A composite pulse sequence that causes a series of magnetic moment rotations that, in combination, are equivalent to a pulse sequence that would cause a single rotation having a target desired rotation angle ? is described. The composite pulse sequence involves a plurality of pulses which each individually have a desired rotation (A°, B° etc) that is less than the target desired rotation ?°. The pulses each cause a rotation about respective axes, that may be orthogonal to each other. Slice selection magnetic gradients can be employed to make the component rotations of the composite pulse slice selective.

Abstract: A frac sand separator system includes a sand separator having an inlet fluidly connected to a well for receiving a fracking return mixture from the well. The sand separator is configured to separate water of the fracking return mixture from particulate matter of the fracking return mixture. The sand separator includes an outlet. The frac sand separator system includes a collection container fluidly connected to the outlet of the sand separator for receiving the particulate matter from the sand separator. At least one outlet valve is fluidly connected between the outlet of the sand separator and the collection container. The frac sand separator system includes a computing device operatively connected to the at least one outlet valve. The computing device includes a processor configured to automatically open the at least one outlet valve such that the particulate matter is released from the sand separator into the collection container.

Abstract: The present invention relates to the field of pulmonary, cardiac and inflammatory disorders. More specifically, the present invention provides methods and compositions for treating disorders associated with Resistin. In a specific embodiment, the present invention provides an antibody that binds human Resistin.

Abstract: A composite pulse sequence for MR systems is described. The pulse sequence involves a plurality of pulses which each individually have a desired rotation (A°, B° etc.) in which the pulses each cause a rotation about respective axes. Slice selection magnetic gradients may be employed to make the component rotations of the composite pulse slice selective. Optionally phase correction (re-phasing) gradients can also be included in the pulse sequence. One or more of the pulses making up the composite pulse are not based on a sinc shaped pulse envelope.

Abstract: A storage assembly includes top and bottom walls, a pair of end walls extending between the top and bottom walls and cooperating with the top and bottom walls to define an interior space, and at least one end surface configured to closely interfit with at least one end surface of an adjacent storage assembly that is substantially similar to the storage assembly at a predefined angular orientation such that a longitudinal axis of the storage assembly is angularly offset from a longitudinal axis of the adjacent storage assembly when the at least one end surface of the storage assembly is interfit with the at least one surface of the adjacent storage assembly The storage assembly may also include a pair of interior walls and a handle relief extending into the top wall and/or a frame assembly located between one of the end walls and one of the interior walls.

Abstract: The invention provides a compound of formula (I): or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.

Abstract: A computer-implemented low-code development platform is provided including a user interface and having access to a library of step macros configured for user configuration and interconnection via the user interface to generate executable code. Each step macro includes a step configuration generator and an execution code generator. The step configuration generator is configured to generate a step configuration file based on user-configurable data points configurable via the user interface. The execution code generator is configured to generate executable code in the form of a compiled step file configured for storage in memory and execution by a processor of a computing system. The execution code generator receives and inputs the step configuration file into a metaprogramming component configured to interpret the user-configurable data points of the step configuration file and to generate and output the compiled step file.

Abstract: The present invention relates to benzimidazole ethers and related compounds which are of use in the field of agriculture as fungicides.

Abstract: The present invention relates to substituted benzimidazoles and related compounds which are of use in the field of agriculture as fungicides.

Abstract: Compounds of formula (I) that are capable of acting as purine receptor antagonists, pharmaceutical compositions including the compounds, and methods of making the compounds, are disclosed. The compounds and compositions can be used in treating or preventing disorders related to purine receptor hyperfunctioning.