Abstract: A method for determining the position of a spacecraft in space, includes cyclically÷ repeating steps of capturing distorted star images; processing the distorted star images to form distorted star group data; storing the distorted star group data; determining a current rotation rate by comparing the distorted star group data of two consecutive cycles; transmitting the current rotation rate to a position control system; and/or the following steps are carried out: processing the distorted star images of a current cycle to form rectified star group data; determining position information by matching the rectified star group data with star group catalog data which is carried along; transmitting the position information to the position control system. A method for determining the position of a spacecraft in space, taking into account known system parameters of an optical system, includes: coding star group catalog data with n = 3...

Abstract: The present invention provides a method for the treatment or prophylaxis of bacterial infections by administering to a subject in need thereof an effective amount of a compound of formula.

Abstract: Provided herein are non-steroidal 17beta-hydroxysteroid dehydrogenase type 1 and type 2 (17?-HSD1 and 17?-HSD2) inhibitors, their production and use, especially for the treatment and for prophylaxis of hormone-related diseases.

Abstract: The present invention provides cystobactamides of formula (I) and the use thereof for the treatment or prophylaxis of bacterial infections.

Abstract: This invention relates to indoline compounds of the structural formula: or their pharmaceutically acceptable salts, wherein the variables are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.

Abstract: This invention relates to indo line compounds of the structural formula I, or their pharmaceutically acceptable salts, wherein the variables are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.

Abstract: Provided herein are non-steroidal 17beta-hydroxysteroid dehydrogenase type 1 and type 2 (17?-HSD1 and 17?-HSD2) inhibitors, their production and use, especially for the treatment and for prophylaxis of hormone-related diseases.

Abstract: This invention relates to indoline compounds of the structural formula: or their pharmaceutically acceptable salts, wherein the variables are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.

Abstract: The present invention relates to compounds which selectively inhibit CYP11B1. Preferably, the compounds of the present invention do not substantially inhibit CYP11B2. Moreover, the compounds of the present invention do not substantially inhibit CYP17 and/or CYP19, either. Amongst other applications of the compounds of the present invention, they can be used for the treatment of Cushing's syndrome or metabolic disease.

Abstract: The present invention provides cystobactamides of formula (I) and the use thereof for the treatment or prophylaxis of bacterial infections:

Abstract: A hybrid network of kinematic sensors of an AOCS, made up of a star sensor including an optical camera head, and a processing unit provided as the central master processing unit, and additional kinematic sensors, each made up of a sensor element and a processing unit connected to the central processing unit via a first bus. An additional processing unit is equivalent to the processing unit and is a redundant central processing unit. The central processing units and—are connected via an additional bus of a spacecraft provided with the hybrid network with the aid of a central computer. The particular active central processing units-provide all kinematic sensors with a uniform time pulse via a synchronization line, and supply the central computer with hybridized kinematic measuring data formed according to a method for hybridization based on the synchronous kinematic measuring data of the star sensor and the measuring data of the other sensors.

Abstract: This invention relates to tricyclic triazole compounds or their pharmaceutically acceptable salts. The inventive compounds selectively inhibit aldosterone synthetase. This invention also provides for pharmaceutical compositions comprising the above-cited compounds or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthetase.

Abstract: The invention relates to compounds for selectively inhibiting human corticosteroid synthases CYP1 1 B1 and CYP1 1 B2, and to the production and use thereof for treating hypercortisolism, diabetes mellitus, hyperaldosteronism, cardiac insufficiency, myocardial fibrosis, depression, age-related cognitive decline and metabolic syndrome.

Abstract: A center console arrangement for a motor vehicle includes a housing arrangement with at least one cover surface arranged thereon. The cover surface includes at least two functional regions. Each functional regions includes at least one display and/or operator control panel. Each of the display and/or operator control panels is assigned, with respect to functionality, to the corresponding functional region.

Abstract: This invention relates to tricyclic triazole compounds or their pharmaceutically acceptable salts. The inventive compounds selectively inhibit aldosterone synthetase. This invention also provides for pharmaceutical compositions comprising the above-cited compounds or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthetase.

Abstract: A device for in situ milling of joint surfaces, including a milling device and a joint clamping device. The joint clamp device is designed to be inserted between two joint components forming a joint, particularly bones, and for pushing the joint components apart with a predetermined or adjustable tension, wherein the joint clamping device includes a recess in which the milling device can be inserted, wherein the milling device includes a face milling cutter.

Abstract: This invention relates to indo line compounds of the structural formula I, or their pharmaceutically acceptable salts, wherein the variables are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.

Abstract: This invention relates to tricyclic triazole analogs of the formula I or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthetase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthetase.

Abstract: A display and operating system of a motor vehicle includes an instrument cluster that is formed by a plurality of display devices and has an outer left-hand display device and an outer right hand display device. A steering wheel of the system includes an outer left-hand operating device configured exclusively for driver interaction with the outer left-hand display device of the instrument cluster and an outer right-hand operating device configured exclusively for driver interaction with the outer right-hand display device of the instrument cluster. Further devices, including at least one of a display device or an operating device, are disposed laterally adjacent to the instrument cluster.

Abstract: A hybrid network of kinematic sensors of an AOCS, made up of a star sensor including an optical camera head, and a processing unit provided as the central master processing unit, and additional kinematic sensors, each made up of a sensor element and a processing unit connected to the central processing unit via a first bus. An additional processing unit is equivalent to the processing unit and is a redundant central processing unit. The central processing units and—are connected via an additional bus of a spacecraft provided with the hybrid network with the aid of a central computer. The particular active central processing units-provide all kinematic sensors with a uniform time pulse via a synchronization line, and supply the central computer with hybridized kinematic measuring data formed according to a method for hybridization based on the synchronous kinematic measuring data of the star sensor and the measuring data of the other sensors.