Abstract: The invention relates to a B-pillar reinforcement of a motor vehicle having an upper region for joining the B-pillar reinforcement to the roof region of the motor vehicle and a lower region for joining the B-pillar reinforcement to a floor support of the motor vehicle, which B-pillar reinforcement comprises at least one hollow profile made of metal, in particular steel, and the hollow profile forms the upper and lower regions of the B-pillar reinforcement. The object of providing an improved B-pillar reinforcement which, on the one hand, is optimised in respect of a load-appropriate configuration with a minimum weight, allows a very good integration of additional components of the B-pillar, is achieved in that the hollow profile has at least to some extent a substantially trapezoidal cross-sectional surface in one of the regions and has an at least partly U-shaped cross-sectional surface in the other region.

Abstract: The present invention relates to a method of producing neopentyl glycol by addition of isobutyraldehyde and formaldehyde in the presence of a tertiary alkylamine as catalyst to give the hydroxypivalinaldehyde with subsequent liquid phase hydrogenation in the presence of a nickel catalyst at a temperature of 80 to 180° C. and at a pressure of 6 to 18 MPa in the presence of an aliphatic alcohol and in the presence of water.

Abstract: The present invention relates to a process for obtaining neopentyl glycol by hydrogenating cracking of high-boilers occurring in the production process in the presence of copper-chromite catalysts. The hydrogenating cracking proceeds in the absence of solvent at a temperature of 140 to 220° C. and at pressures of 7 to 28 MPa.

Abstract: The invention relates to salts of 6-heteroaryl substituted hexahydrophenanthridine PDE4 inhibiting compounds, which can be used in the pharmaceutical industry for the production of pharmaceutical composition for use, e.g., in treatment of airway disorders.

Abstract: The compound 1-(2-{4-[3-(3,4-dimethoxyphenyl)-4,4-dimethyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]piperidin-1-yl}-2-oxoethyl)pyrrolidine-2,5-dione is a novel effective inhibitor of the type 4 phosphodiesterase.

Abstract: The compounds of a certain formula 1, in which R1, R7, R8, R9 and n have the meanings as given in the description, are novel effective inhibitors of the type 4 phosphodiesterase.

Abstract: An apparatus and method is described for measuring a local surface temperature of a semiconductor device under stress. The apparatus includes a substrate, and a reference MOSFET. The reference MOSFET may be disposed closely adjacent to the semiconductor device under stress. A local surface temperature of the semiconductor device under stress may be measured using the reference MOSFET, which is not under stress. The local surface temperature of the semiconductor device under stress may be determined as a function of drain current values of the reference MOSFET measured before applying stress to the semiconductor device and while the semiconductor device is under stress.

Abstract: A cover that is assembled from a front assembly (3+6) and a base element (2) is produced in that the front assembly including the front plate (3) and the light conductor pin (6) are integrally injection molded in two subsequent injection molding steps, while the base element (2) is injection molded remote there from. Subsequently, the two components which are arranged in the different tool halves (101, 102) are brought in alignment with one another with an index plate (103) and are joined through closing the tool and are preferably interlocked with one another.

Abstract: Compounds of a certain formula I, in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, as well as salts thereof are novel effective HDAC inhibitors.

Abstract: An apparatus and method is described for measuring a local surface temperature of a semiconductor device under stress. The apparatus includes a substrate, and a reference MOSFET. The reference MOSFET may be disposed closely adjacent to the semiconductor device under stress. A local surface temperature of the semiconductor device under stress may be measured using the reference MOSFET, which is not under stress. The local surface temperature of the semiconductor device under stress may be determined as a function of drain current values of the reference MOSFET measured before applying stress to the semiconductor device and while the semiconductor device is under stress.

Abstract: The compounds of formula I in which R1, R2, R3, R4, R5, R6 and n have the meanings as indicated in the description, are novel effective PDE3/4 inhibitors.

Abstract: Compounds of a certain formula I, in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, as well as salts thereof are novel effective HDAC inhibitors.

Abstract: A compound of Formula (I): is useful in the treatment or prevention of a disease or medical condition mediated through glucokinase (GLK or GK), leading to a decreased glucose threshold for insulin secretion.

Abstract: In order for light conductor pins (6) in dead hole channels (5) of a plastic cover not to be melted together at their entire side walls with the cover they are produced through a particular injection molding tool in the same tool as the cover and the tool slide (104) which is a component of the injection molding tool (100) is aligned in the injection molding tool (100) with the dead hole channels (5) and inserted into the dead hole channels. The front plate is integrally molded with the base component before or after the light conductor pins are inserted into the base component. When the integral molding is performed after inserting the light conductor pins (6) the integral molding is also provided e.g. at a face of the inserted light conductor pins (6).

Abstract: A mail processing system has an infeed line coupled to receive a first article from a feeder. A loading device is coupled to receive the first article from the infeed line at a first speed, and a transfer unit is coupled to receive the first article from the loading device, wherein the transfer unit is configured to transport the first article at a second speed, which is lower than the first speed.

Abstract: (2S)-2-[1-(2-Chloro-6-cyano-phenyl)pyrazolo[4,5-e]pyrimidin-4-yl]oxy-3-[(1R)-2-hydroxy-1-methyl-ethoxy]-N-(5-methylpyrazin-2-yl)propanamide or a pharmaceutically acceptable salt thereof is useful in the treatment or prevention of a disease or medical condition mediated through glucokinase (GLK or GK), leading to a decreased glucose threshold for insulin secretion.

Abstract: A sorting installation for letters of a first kind and letters of a second kind includes circulating stacking locations for receiving the letters of the first kind delivered in any desired sequence, and circulating end locations ordered by destination addresses. A first controller is operable to transfer a letter of the first kind from a circulating stacking location to an end location assigned to a destination address of the letter of the first kind. The installation includes further letter-stacking locations for letters of the second kind. A second controller is operable to transfer a letter of the second kind from a letter-stacking location to an end location assigned to a destination address of the letter of the second kind.

Abstract: A transfer device for mail items with a transfer unit which has an ejection point for transferring individualized mail items to an item carrier is provided. Further, the transfer device includes a transport device for transporting the mail items to the ejection point in a direction of transport. The transport device includes two belts for holding the mail items on both sides and for transporting the mail items and further has means for adapting a space between the belts to the thickness of a mail item. The means for adapting is a belt tilt means which is pivotal about an axis of rotation, the pivotal movement pivoting one of the belts and therefore a distance between the belts is variable.

Abstract: The present invention relates to a process for obtaining neopentyl glycol by hydrogenating cracking of high-boilers occurring in the production process in the presence of copper-chromite catalysts. The hydrogenating cracking proceeds in the absence of solvent at a temperature of 140 to 220° C. and at pressures of 7 to 28 MPa.

Abstract: The present invention relates to a method of producing neopentyl glycol by addition of isobutyraldehyde and formaldehyde in the presence of a tertiary alkylamine as catalyst to give the hydroxypivalinaldehyde with subsequent liquid phase hydrogenation in the presence of a nickel catalyst at a temperature of 80 to 180° C. and at a pressure of 6 to 18 MPa in the presence of an aliphatic alcohol and in the presence of water.