Abstract: The invention relates to pantoprazole and (S)-pantoprazole salts and to medicaments comprising these compounds.

Abstract: The invention relates to salts of 6-heteroaryl substituted hexahydrophenanthridine PDE4-inhibiting compounds, which can be used in the pharmaceutical industry for the production of pharmaceutical compositions for use, e.g., in treatment of airway disorders.

Abstract: A mail processing system has an infeed line coupled to receive a first article from a feeder. A loading device is coupled to receive the first article from the infeed line, and a transfer unit is coupled to receive the first article from the loading device. A transport vehicle is configured to move in proximity of the transfer unit along a first linear path, wherein the transfer unit is configured to move synchronously and parallel to the first transport unit, and wherein the transfer unit is configured to transfer the first article to the first transport vehicle.

Abstract: A sorting installation for letters of a first kind and letters of a second kind includes circulating stacking locations for receiving the letters of the first kind delivered in any desired sequence, and circulating end locations ordered by destination addresses. A first controller is operable to transfer a letter of the first kind from a circulating stacking location to an end location assigned to a destination address of the letter of the first kind. The installation includes further letter-stacking locations for letters of the second kind. A second controller is operable to transfer a letter of the second kind from a letter-stacking location to an end location assigned to a destination address of the letter of the second kind.

Abstract: The present invention provides novel polynucleotides encoding HGPRBMY23 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel HGPRBMY23 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, particularly renal diseases and/or disorders, colon cancer, breast cancer, and diseases and disorders related to aberrant NFKB modulation. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

Abstract: The present invention provides novel polynucleotides encoding HGPRBMY23 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel HGPRBMY23 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, particularly renal diseases and/or disorders, colon cancer, breast cancer, and diseases and disorders related to aberrant NFKB modulation. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

Abstract: The invention relates to a method for operating a telecommunication system, including in particular a mobile radio network (PLMN), to provide a service and to obtain information.

Abstract: A vehicle seat, in particular functioning as a rear vehicle seat having a seat element provided at the free end of the backrest, and a vehicle with such a seat are specified in which the seat element is pivotably linked to a backrest structure of the vehicle seat and the seat element acts at the same time as a headrest and as protection against rollover.

Abstract: The invention relates to the identification and cloning of a two novel full-length human SLAP-2 variants and their encoded polypeptides, hSLAP-2v3 and hSLAP-2v4. hSLAP-2v3 and hSLAP-2v4 are members of the SLAP family of adapter proteins and are involved in the negative regulation of intracellular T-cell signal transduction. The invention further relates to the use of these novel hSLAP-2v3 and hSLAP-2v4 polynucleotides and their encoded polypeptides as targets for therapeutic intervention in immunological and inflammatory disorders, autoimmune diseases, pulmonary diseases, proliferative immune disorders, and cancer.

Abstract: The present invention provides polynucleotides encoding human and murine guanylate binding protein polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The present invention further relates to diagnostic and therapeutic methods for applying the guanylate binding protein polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, such as rheumatoid arthritis and/or conditions related to aberrant NF-?B activity, guanylate binding activity and GTPase activity. The present invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

Abstract: A method for processing a batch of mail wherein a mail sorting machine sorts the batch of mail to a plurality of sorting bins according to a predetermined sorting plan includes steps of reading an identification code from an empty mail tray, loading the empty tray in a buffer storage unit associated with one of the sorting bins, activating a switch associated with the buffer storage unit to confirm that the mail tray is positioned in the buffer, assigning the tray identification code to a destination associated with the sorting bin in the sorting plan, and then sorting mail to the sorting bin and transferring sorted mail from the sorting bin into the mail tray.

Abstract: The invention relates to a container for flat objects in a vertical position, comprising a base, two lateral longitudinal sides and two front sides, the flat objects being aligned with their largest surfaces facing the front sides. At least one front side consists of at least one material web, whose axes run parallel to the base, which is mobile in relation to the front side and can be displaced downwards into a gap in the base. The material web is flexible and thin and is suspended by its ends that run perpendicular to the longitudinal sides between two bars. The lower bar is configured in the gap in the base and is displaceable and the upper bar can be displaced between the base and the upper edge along the front delimitation of the longitudinal sides.

Abstract: The compounds of formula I in which R1, R2, R3, R4, R5, R6 and n have the meanings as indicated in the description, are novel effective PDE3/4 inhibitors.

Abstract: The present invention relates to a method and a device for stacking flat mailings, in which the thickness of each individually conveyed mailing that is to be stacked is detected within a main control loop. The underfloor belt is displaced away from the stacking location by a distance that corresponds to the measured thickness minus a specific distance by means of a stack support for the arriving mailing. The stacking force is measured at different heights in the area of the stacking roll in a static correcting control loop and is re-regulated by moving the underfloor belt within set point values established for the allowed stacking force ranges once each mailing has reached the stop.

Abstract: Human PRMT genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of PRMT are provided.

Abstract: A semiconductor circuit element for reducing undesirable charging effects for a connection element of test structures for semiconductor circuits is disclosed. A surface of a semiconductor circuit element has interconnect structures that are electrically insulated from the remainder of the surface of the semiconductor circuit element, where exclusively the interconnect structures are connected to semiconductor circuit elements arranged downstream.

Abstract: The present invention relates to a method and a device for stacking flat mailings, in which the thickness of each individually conveyed mailing that is to be stacked is detected within a main control loop. The underfloor belt is displaced away from the stacking location by a distance that corresponds to the measured thickness minus a specific distance by means of a stack support for the arriving mailing. The stacking force is measured at different heights in the area of the stacking roll in a static correcting control loop and is re-regulated by moving the underfloor belt within set point values established for the allowed stacking force ranges once each mailing has reached the stop.

Abstract: According to the invention, the items to be posted are held by a stacking support which can be displaced in a stacking direction and is coupled to a flush-mounted strip on which the stack is arranged, and by a parallel stacking wall which is located in a vertical position on the stacking spot, oriented towards an abutment wall. Said items to be posted are supplied and stacked by means of stacking belts and a stacking roll which projects from the stacking wall and is located at the entrance to the stack receiving installation, close to the abutment wall, said stacking roll being mounted in a deflectable manner. A connecting element is used to connect the stacking roll housing to the force transducer of a device for measuring the stacking pressure perpendicularly to the resulting belt force exerted on the stacking roll.

Abstract: The invention relates to a container for flat objects in a vertical position, comprising a base, two lateral longitudinal sides and two front sides, the flat objects being aligned with their largest surfaces facing the front sides. At least one front side consists of at least one material web, whose axes run parallel to the base, which is mobile in relation to the front side and can be displaced downwards into a gap in the base. The material web is flexible and thin and is suspended by its ends that run perpendicular to the longitudinal sides between two bars. The lower bar is configured in the gap in the base and is displaceable and the upper bar can be displaced between the base and the upper edge along the front delimitation of the longitudinal sides.

Abstract: A system provided in a high-speed continuous casting plant for casting a metallic strand for automatically operating the high-speed continuous casting plant. In the system, the stopping or slide movement, the modification of the steel level, the heat currents through the mold walls, the temperature of the liquid metal and the drawing-off speed are measured over the casting time, supplied to a computer and compared with predetermined limit values for an automatic operating mode.