Patents by Inventor Roman Sakowicz

Roman Sakowicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and assays utilizing ADP or phosphate for detecting protein modulators
    Patent number: 6410254
    Abstract: Described herein are methods which identify candidate agents as binding to a protein or as a modulator of the binding characteristics or biological activity of a protein. Generally, the methods involve the use of ADP or phosphate. The assays can be used in a high throughput system to obviate the cumbersome steps of using gels or radioactive materials.
    Type: Grant
    Filed: May 18, 1999
    Date of Patent: June 25, 2002
    Assignee: Cytokinetics
    Inventors: Jeffrey T. Finer, Fady Malik, Roman Sakowicz, Christopher Shumate, Kenneth Wood
  • Motor proteins and methods for their use
    Patent number: 6391613
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKif15, antibodies to HsKif15, methods of screening for HsKif15 modulators using biologically active HsKif15, and kits for screening for HsKif15 modulators.
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: May 21, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Christophe Beraud, Roman Sakowicz, Kenneth W. Wood
  • Motor proteins and method for their use
    Patent number: 6379912
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKif15, antibodies to HsKif15, methods of screening for HsKif15 modulators using biologically active HsKif15, and kits for screening for HsKif15 modulators.
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: April 30, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Christophe Beraud, Roman Sakowicz, Kenneth W. Wood
  • Motor proteins and methods for their use
    Patent number: 6355466
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKif15, antibodies to HsKif15, methods of screening for HsKif15 modulators using biologically active HsKif15, and kits for screening for HsKif15 modulators.
    Type: Grant
    Filed: May 17, 2000
    Date of Patent: March 12, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Christophe Beraud, Roman Sakowicz, Kenneth W. Wood
  • High throughput sarcomeric assay
    Publication number: 20020022716
    Abstract: The present invention provides high throughput screening systems for identifying compounds that modulate the biological activity of a biochemically functional sarcomere. The method can be performed in plurality simultaneously with fluorescence or absorbance readouts.
    Type: Application
    Filed: September 26, 2001
    Publication date: February 21, 2002
    Inventors: James J. Hartman, Fady Malik, Roman Sakowicz, Jeffrey T. Finer
  • Motor proteins and methods for their use
    Patent number: 6331424
    Abstract: The present invention provides high throughput screening systems for identifying compounds useful in the treatment of cellular proliferation disorders. The method can be performed in plurality simultaneously with fluorescence or absorbance readouts.
    Type: Grant
    Filed: June 15, 2000
    Date of Patent: December 18, 2001
    Assignee: Cytokinetics, Inc.
    Inventors: Christophe Beraud, Roman Sakowicz
  • Antifungal assay
    Patent number: 6284480
    Abstract: The present invention provides high throughput screening systems for identifying antifungal compounds. The method can be performed in plurality simultaneously with fluorescence or absorbance readouts.
    Type: Grant
    Filed: April 3, 2000
    Date of Patent: September 4, 2001
    Assignee: Cytokinetics, Inc.
    Inventors: Corey E. Nislow, Roman Sakowicz, Christophe Beraud
  • Kinesin motor modulators derived from the marine sponge Adocia
    Patent number: 6207403
    Abstract: This invention provides novel compounds derived from a marine sponge, Adocia sp., that specifically modulat kinesin activity by targeting the kinesin motor domain and mimicking the activity a microtubule. The compounds act as potent anti-mitogens are useful in a wide variety of in vitro and in vivo applications.
    Type: Grant
    Filed: January 6, 1999
    Date of Patent: March 27, 2001
    Assignee: The Regents of the University of California
    Inventors: Lawrence S. B. Goldstein, David John Faulkner, Roman Sakowicz, Michael S. Berdelis, Christine L. Blackburn, Cordula Hopmann