Abstract: The present invention relates to a composition of (S)-3-aminomethyl-5-methylhexanoic acid or a pharmaceutically acceptable salt thereof, and riluzole. The composition has broad application prospects in the manufacture of a medicament for treating neuropathic pain.

Abstract: The application discloses a method, system, device, and storage medium for determining a cleaning path. The method includes: in response to a cleaning instruction from a cleaning robot, controlling the cleaning robot to rotate a preset angle on the surface to be cleaned based on a target rotation direction; detecting whether the cleaning robot generates a first edge corner trigger signal during its rotation; and determining a working path of the cleaning robot on a surface to be cleaned based on the detecting result of the first edge corner trigger signal. This application automatically determines the working path based on the detecting result of the first edge corner trigger signal, which, compared to existing technologies that rely on manually selecting the working path, ensures the adaptability of the working path to the surface to be cleaned.

Abstract: A driving method includes driving a display panel at a first-frequency driving mode and a second-frequency driving mode. A first frequency of the first-frequency driving mode is lower than a second frequency of the second-frequency driving mode. In the first-frequency driving mode, a frame time includes a scanning section and a corresponding front and rear porch section immediately following the scanning section. The driving method further includes scanning sub-pixels of the display panel in the scanning section of the first-frequency driving mode, where in the front and rear porch section, the sub-pixels of the display panel are not scanned, and front and rear porch sections corresponding to at least part of a plurality of frames in the first-frequency driving mode include at least one compensation section. The method further includes providing a data signal to each data line of a plurality of data lines of the display panel in a compensation section of the at least one compensation section.

Abstract: The present disclosure is suitable for the field of hardware chip design, and particularly relates to an alias processing method and system based on L1D-L2 caches and a related device. A method for solving an alias problem of the L1D cache based on a L1D cache-L2 cache structure and a corresponding system module are disclosed. The method provided by the present disclosure can maximize hardware resource efficiency, without limiting a chip structure, a hardware system type, an operating system compatibility and a chip performance, and meanwhile, the module realized based on the cache cannot greatly increase power consumption of the whole system, thus having good expandability.

Abstract: A magneto-optic thin film includes a substrate; a diffusion barrier layer disposed on the substrate, where the diffusion barrier layer includes a metal oxide; a buffer layer disposed on the diffusion barrier layer; and an optical isolation layer disposed on the buffer layer. The metal oxide in the diffusion barrier layer growing on the substrate is polycrystalline.

Abstract: A clipless pedal device is provided, including a pedal body; an engagement portion; a retaining portion, disposed on the pedal body and being movable between a lock position and a release position; a push portion, driven by the retaining portion to move along a pushing path; wherein when a cleat is engaged between the engagement portion and the retaining portion, the cleat is located on the pushing path; while the retaining portion is moved from the lock position to the release position, the push portion is moved along the pushing path to push the cleat.

Abstract: Provided is a biochar-anaerobic membrane biological treatment system and process. The system mainly includes a reaction tank, a membrane module, a macroporous gas distribution device, low-temperature pyrolysis biochar. The application of the process to sewage treatment shows that: under the conditions that the hydraulic retention time is 3.2-7.2 h, the membrane flux is 12.0-17.8 L/m2/h, and the sludge concentration of 7.2-15.6 g/L, multiple objectives of promoting organic micropollutants (OMPs) biotransformation, accelerating methane production and strengthening membrane fouling control were achieved. The system improved OMPs removal efficiency by more than 20%, decreased membrane fouling rate by 50%, and reaching an organic matter removal efficiency of more than 86% at low temperature. The system and process solve the problems of poor OMPs removal efficiency, serious membrane fouling, and low methane yield at low temperature in the anaerobic membrane biological treatment system.

Abstract: The present invention relates to a drug conjugate of recombinant human serum albumin and a therapeutic drug. The drug conjugate is formed by covalent coupling a therapeutic drug to a free sulfhydryl group at position 34 of recombinant human serum albumin via a heterobifunctional linker. The drug conjugate of the present invention not only enhances the pharmacological action and improves the pharmacokinetics of the therapeutic drug, but also significantly increases the coupling efficiency of the therapeutic drug to human serum albumin, thereby reducing the production cost of the drug conjugate.

Abstract: A composition applied to preparation of a medicament for treating cerebrovascular diseases, in particular ischemic cerebrovascular diseases. The composition contains 2-amino-6-trifluoromethoxybenzothiazole or a pharmaceutically acceptable salt thereof and borneol. By means of the compatibility between 2-amino-6-trifluoromethoxybenzothiazole and d-borneol, according to non-clinical cell test and animal efficacy test results, for cerebrovascular diseases, 2-amino-6-trifluoromethoxybenzothiazole and d-borneol have the effect of synergistically increasing efficacy.

Abstract: Disclosed are a shield tunnel segment structure and a construction method thereof. The shield tunnel segment structure includes segment blocks sequentially spliced in a circumferential direction. Each segment block forms a closed annular segment structure, and outer diameters of adjacent annular segment structures gradually increase in an axial direction. At least two adjacent segment blocks of the same annular segment structure form an annular inner groove, and at least one segment block of the adjacent annular segment structures is provided with an inner bump which matches the annular inner groove. At least two adjacent segment blocks of the same annular segment structure form an annular outer groove, and at least one segment block of the adjacent annular segment structures is provided with an outer bump which matches the annular outer groove. The annular outer grooves and the annular inner grooves are staggered in the circumferential direction.

Abstract: Disclosed is the use of a composition containing cilostazol or a pharmaceutically acceptable salt thereof and edaravone in the preparation of a drug for treating cerebrovascular diseases, especially ischemic cerebrovascular diseases. The experiment result shows that the tail vein administration of 1-15 mg/kg of cilostazol or 1.67-8.33 mg/kg of edaravone on rats with a focal cerebral ischemia-reperfusion injury can significantly ameliorate neurological defects in rats with an MCAO and reduce a cerebral infarction area; and performing compound combination within the dosage range (the mass ratio of cilostazol:edaravone is 1:5 to 5:1) can be synergistic. The tail vein administration of 3.33-16.67 mg/kg of cilostazol or 3.33-16.67 mg/kg of edaravone on mice with a focal cerebral ischemia-reperfusion injury can significantly ameliorate neurological defects in mice with an MCAO and reduce a cerebral infarction area.

Abstract: A triboelectric nanogenerating device is configured for providing an electric power to an electronic device and the triboelectric nanogenerating device includes at least one scaly triboelectric membrane configured for providing the electric power to the electronic device by frictional electrification. The at least one scaly triboelectric membrane includes a keratin and a polyvinyl alcohol, the at least one scaly triboelectric membrane has a first triboelectric surface, and the first triboelectric surface of the at least one scaly triboelectric membrane includes a plurality of scaly layers. Each of the scaly layers is arranged in order and extends along an orienting direction. A distal end of each of the scaly layers has a plurality of saw-tooth structures.

Abstract: A method for measuring coordinate position include detecting the distance of a target relative to a portable electronic device to generate a measurement signal corresponding to the distance, sensing a relative position of the target to generate a azimuth angle corresponding to the relative position, detecting the movement of the portable electronic device to generate an inertial signal corresponding to the movement, obtaining positioning information of the portable electronic device, converting the measurement signal into distance data, converting the inertial signal into a tilt angle, calculating coordinate difference information with the tilt angle, the distance data and the azimuth angle, and calculating coordinate position of the target with the positioning information and the coordinate difference information.

Abstract: The present disclosure discloses a swing structure and a corresponding water outlet device. A water passing chamber in a body of the swing structure is equipped with a swing member, and an upper end of the swing member is provided with a recess facing a water inlet hole of the water passing chamber. The water flow impacts the recess to drive the swing member to swing to one side randomly. After a lower end of the swing member is out of range of a water outlet hole of the water passing chamber, the upper and lower ends of the swing member are adjacent to or abut against a wall of the water passing chamber, so that the swing member can swing back and forth.

Abstract: An enhancement mode high electron mobility transistor (HEMT) includes a group III-V semiconductor body, a group III-V barrier layer and a gate structure. The group III-V barrier layer is disposed on the group III-V semiconductor body, and the gate structure is a stacked structure disposed on the group III-V barrier layer. The gate structure includes a gate dielectric and a group III-V gate layer disposed on the gate dielectric, and the thickness of the gate dielectric is between 15 nm to 25 nm.

Abstract: The present application provides a fractional domain noise reduction method for a power signal, including: S1: estimating an optimal fractional Fourier transform angle {circumflex over (?)}0 of an original signal x(t); S2: calculating fractional Fourier transform of the original signal under the optimal fractional Fourier transform angle to obtain X{circumflex over (?)}0 (u); S3: performing band-pass filtering in an optimal fractional Fourier transform domain to obtain X{circumflex over (?)}0 (u)H(u); S4: calculating fractional Fourier transform of X{circumflex over (?)}0 (u)H(u) at an angle of ?X{circumflex over (?)}0 and S5: judging whether {circumflex over (?)}0 is equal to ?/2, if yes, ending the noise reduction, and if no, eliminating a recovered signal component x(t)=x(t)?X{circumflex over (?)}0(u)H(u), and then repeating the steps S1 to S5 again until the estimated optimal FRFT rotation angle is equal to ?/2.

Abstract: An optical fiber transmission device includes a substrate, a photonic integrated circuit, and an optical fiber assembly. The photonic integrated circuit is disposed on an area of the substrate. The substrate has a protruding structure at an interface with an edge of the photonic integrated circuit. The optical fiber assembly includes an optical fiber and a ferrule that sleeves the optical fiber. The protruding structure of the substrate is configured to abut against the ferrule to limit the position of the optical fiber assembly in a vertical direction of the substrate, such that the protruding structure is a stopper for the optical fiber assembly in the vertical direction.

Abstract: An optical fiber network device includes a fiber and a photonic integrated circuit. Fiber receives a first optical signal and transmits a second optical signal. A first wavelength of first optical signal is different from a second wavelength of second optical signal. Photonic integrated circuit includes a laser chip, a photodetector, a wavelength division multiplexing coupler, a first optical modulation element and a second optical modulation element. Laser chip is disposed on photonic integrated circuit, and is configured to generate first optical signal. Photodetector detects second optical signal. Wavelength division multiplexing coupler is configured to couple first optical signal to fiber, and receives second optical signal. First optical modulation element is coupled to wavelength division multiplexing coupler and laser chip, and is configured to modulate first optical signal.

Abstract: The present invention belongs to the pharmaceutical field, and relates to an application of a cilostazol and d-borneol composition in preparing a drug for treating cerebrovascular disease, in particular ischemic cerebrovascular disease. The present invention specifically relates to a composition containing cilostazol or a pharmaceutically acceptable salt thereof and d-borneol, and an application of the composition in preparing a drug for treating cerebrovascular disease, in particular ischemic cerebrovascular disease.