Abstract: Processes for making propylene-based copolymers having broad molecular weight distributions and broad comonomer distributions using a single tubular reactor. Processes for making a propylene-based copolymer can include introducing propylene and at least one other olefin comonomer to a tubular reactor to produce a propylene-based copolymer having a broad comonomer distribution, a Mw of about 10 kg/mol to about 2.000 kg/mol, and a MWD of about 2.0 to about 10.0. The tubular reactor can include one or more heat exchanger elements, preferably a spiral heat exchanger. Propylene-based copolymer compositions can include propylene derived units and at least one other comonomer derived units, wherein the copolymer compositions have a broad comonomer distribution, a Mw of about 10 kg/mol to about 2.000 kg/mol, and a MWD of about 2.0 to about 10.0. Such compositions can have broad orthogonal comonomer distributions.

Abstract: An STL model slicing method includes: reading and loading an STL model; obtaining a first slice plane; according to a first set thickness, making the first slice plane be horizontally tangential to an STL model to obtain a first profile curve, which is a profile curve of a tangent plane of the STL model and the first slice plane; determining whether the profile curve contains a physical portion of the STL model; if the profile curve contains the physical portion of the STL model, filling the physical portion with white to obtain a white portion; determining a non-physical portion in the profile curve according to the physical portion; filling the non-physical portion with black to form a mask of the tangent plane; and projecting the mask onto a liquid photosensitive resin by means of a first 3D printer, and then curing the white portion to be a first cured profile.

Abstract: Provided is an antigen-binding protein having the following properties: (a) specifically binding to CDH6, and (b) having the activity of being internalized into CDH6-expressing cells by binding to CDH6. Further provided an immunoconjugate comprising an antibody or antigen binding fragment thereof that specifically binds to CDH6 and has internalization activity, a pharmaceutical product comprising the immunoconjugate and having therapeutic effects on a tumor, a method for treating a tumor using the immunoconjugate or the pharmaceutical product, and the like.

Abstract: An intelligent seed production apparatus and method based on multistage screening and bud eye identification includes a feeding module, a pre-cutting module, a bud eye identifying and cutting module, and a material mixing module. The feeding module can screen out seed potatoes with the mass and shapes meeting the requirements through a multistage screening mechanism. The pre-cutting module can receive the seed potatoes discharged from the feeding module, and cut each seed potato in half; the bud eye identifying and cutting module can receive the seed potato pieces discharged from the pre-cutting module and determine the weight of the seed potatoes and identify the bud eye distribution on the surfaces of the seed potatoes, and cut the seed potato into multiple required tubers, so that bud eyes are distributed on different tubers uniformly. The material mixing module can receive the cut tubers, and complete the material mixing of the tubers.

Abstract: Provided herein are methods for detecting a target moiety in a biological sample suspected of containing the target moiety, by incubating the biological sample with an antibody and a fusion polypeptide, the fusion polypeptide comprising (i) an immunoglobulin-binding polypeptide and (ii) a reporting species.

Abstract: Disclosed are a power amplifier, comprising a main power amplifier unit, an auxiliary power amplifier unit, an envelope acquisition unit and a power control unit, wherein input ends of both the main power amplifier unit and an input end of the auxiliary power amplifier unit are connected to an electrical signal, and output ends of the two are coupled to each other; the power control unit comprises a first power control assembly and/or a second power control assembly, at least one main power amplifier unit is connected to the electrical signal through the first power control assembly, and a control end of the first power control assembly is connected to the envelope acquisition unit; and at least one auxiliary power amplifier unit is connected to the electrical signal through the second power control assembly, and a control end of the second power control assembly is connected to the envelope acquisition unit.

Abstract: Methods of treating autoimmune diseases, such as systemic lupus erythematosus using domain antibodies that specifically bind human CD28 are provided. The methods may comprise at least one administration cycle comprising one dose of the domain antibody. The method reduces symptoms of systemic lupus erythematosus compared to placebo.

Abstract: Methods of treating autoimmune diseases, such as systemic lupus erythematosus using domain antibodies that specifically bind human CD28 are provided. The methods may comprise at least one administration cycle comprising one dose of the domain antibody. The method reduces symptoms of systemic lupus erythematosus compared to placebo.

Abstract: Methods of treating autoimmune diseases, such as systemic lupus erythematosus using domain antibodies that specifically bind human CD28 are provided. The methods may comprise at least one administration cycle comprising one dose of the domain antibody. The method reduces symptoms of systemic lupus erythematosus compared to placebo.

Abstract: Methods of treating autoimmune diseases, such as systemic lupus erythematosus using domain antibodies that specifically bind human CD28 are provided. The methods may comprise at least one administration cycle comprising one dose of the domain antibody. The method reduces symptoms of systemic lupus erythematosus compared to placebo.

Abstract: A multi-function flashlight that includes a flashlight body, an optic having a focusing portion and a non-focusing portion, a main LED positioned to direct light through the focusing portion, and one or more additional LEDs positioned to direct light through the non-focusing portion. A power source may be disposed within the flashlight body adapted to provide power to the main and additional LEDs, and a first control may be included that is configured to selectively provide power to the primary LED.

Abstract: A method of treating an inflammatory bowel disease is provided. The method comprises administration of an antibody polypeptide that specifically binds a novel epitope of human CD40. The antibody polypeptides do not exhibit CD40 agonist activity. The antibody polypeptides may be fusions of a domain antibody (dAb) comprising a single VL or VH domain and an Fc domain.

Abstract: A multi-function flashlight that includes a flashlight body, an optic having a focusing portion and a non-focusing portion, a main LED positioned to direct light through the focusing portion, and one or more additional LEDs positioned to direct light through the non-focusing portion. A power source may be disposed within the flashlight body adapted to provide power to the main and additional LEDs, and a first control may be included that is configured to selectively provide power to the primary LED.

Abstract: A work light including a body with an upper portion having a slot defined therein, the slot encompassing a pivoting portion, the pivoting portion carrying a lens and a light source, the pivoting portion pivoting the lens and the light source in an arc of at least about 180 degrees.