Abstract: Provided herein are methods for detecting a target moiety in a biological sample suspected of containing the target moiety, by incubating the biological sample with an antibody and a fusion polypeptide, the fusion polypeptide comprising (i) an immunoglobulin-binding polypeptide and (ii) a reporting species.

Abstract: Disclosed are a power amplifier, comprising a main power amplifier unit, an auxiliary power amplifier unit, an envelope acquisition unit and a power control unit, wherein input ends of both the main power amplifier unit and an input end of the auxiliary power amplifier unit are connected to an electrical signal, and output ends of the two are coupled to each other; the power control unit comprises a first power control assembly and/or a second power control assembly, at least one main power amplifier unit is connected to the electrical signal through the first power control assembly, and a control end of the first power control assembly is connected to the envelope acquisition unit; and at least one auxiliary power amplifier unit is connected to the electrical signal through the second power control assembly, and a control end of the second power control assembly is connected to the envelope acquisition unit.

Abstract: Methods of treating autoimmune diseases, such as systemic lupus erythematosus using domain antibodies that specifically bind human CD28 are provided. The methods may comprise at least one administration cycle comprising one dose of the domain antibody. The method reduces symptoms of systemic lupus erythematosus compared to placebo.

Abstract: Methods of treating autoimmune diseases, such as systemic lupus erythematosus using domain antibodies that specifically bind human CD28 are provided. The methods may comprise at least one administration cycle comprising one dose of the domain antibody. The method reduces symptoms of systemic lupus erythematosus compared to placebo.

Abstract: Methods of treating autoimmune diseases, such as systemic lupus erythematosus using domain antibodies that specifically bind human CD28 are provided. The methods may comprise at least one administration cycle comprising one dose of the domain antibody. The method reduces symptoms of systemic lupus erythematosus compared to placebo.

Abstract: Methods of treating autoimmune diseases, such as systemic lupus erythematosus using domain antibodies that specifically bind human CD28 are provided. The methods may comprise at least one administration cycle comprising one dose of the domain antibody. The method reduces symptoms of systemic lupus erythematosus compared to placebo.

Abstract: A multi-function flashlight that includes a flashlight body, an optic having a focusing portion and a non-focusing portion, a main LED positioned to direct light through the focusing portion, and one or more additional LEDs positioned to direct light through the non-focusing portion. A power source may be disposed within the flashlight body adapted to provide power to the main and additional LEDs, and a first control may be included that is configured to selectively provide power to the primary LED.

Abstract: A method of treating an inflammatory bowel disease is provided. The method comprises administration of an antibody polypeptide that specifically binds a novel epitope of human CD40. The antibody polypeptides do not exhibit CD40 agonist activity. The antibody polypeptides may be fusions of a domain antibody (dAb) comprising a single VL or VH domain and an Fc domain.

Abstract: A multi-function flashlight that includes a flashlight body, an optic having a focusing portion and a non-focusing portion, a main LED positioned to direct light through the focusing portion, and one or more additional LEDs positioned to direct light through the non-focusing portion. A power source may be disposed within the flashlight body adapted to provide power to the main and additional LEDs, and a first control may be included that is configured to selectively provide power to the primary LED.

Abstract: A work light including a body with an upper portion having a slot defined therein, the slot encompassing a pivoting portion, the pivoting portion carrying a lens and a light source, the pivoting portion pivoting the lens and the light source in an arc of at least about 180 degrees.

Abstract: Disclosed are a method for multi-picture control in a video conference, a related device, and a storage medium. An MCU supports a multi-site video conference; and in the method, the process executed by the MCU comprises: when a conference is initially started, the MCU sending unified conference site picture information to a video terminal in each conference site; and during the conference, the MCU sending corresponding customized conference site picture information to some video terminals according to conference site picture customization requests of the video terminals.

Abstract: Disclosed are flashlights that optimize the light output and beam focus of both a flood beam and a spot beam. The disclosed flashlights include a housing member and a lens including a first focusing element adapted to shape a light beam into a spot beam and a second focusing element adapted to shape a light beam into a flood beam. A first LED is positioned to direct light through the first focusing element, and a second LED positioned to direct light through the second focusing element. The first LED has a smaller die than the second LED, and the distance between the first LED and the first focusing element is greater than the distance between the second LED and the second focusing element.