Patents by Inventor Rui Liang

Rui Liang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10806804
    Abstract: The present invention provides compounds that have motifs that target the compounds to cells that express integrins. In particular, the compounds have peptides with one or more RD motifs conjugated to an agent selected from an imaging agent and a targeting agent. The compounds may be used to detect, monitor and treat a variety of disorders mediated by integrins.
    Type: Grant
    Filed: May 5, 2016
    Date of Patent: October 20, 2020
    Assignee: Washington University
    Inventors: Samuel Achilefu, Kexian Liang, Rui Tang
  • Patent number: 10795778
    Abstract: This application relates to a shared data recovery method performed at a first node of a data sharing system. The first node obtains a first eigenvalue of a first node after receiving a recovery request carrying a first block height; broadcasts the first eigenvalue to at least one second node and recovery indication information to the at least one second node. After determining, based on the first eigenvalue and a plurality of second eigenvalues, that data in shared data stored by all nodes of the data sharing system is consistent, the first node recovers data within a range of the first block height in the shared data after receiving a preset quantity of a plurality of pieces of recovery indication information, thereby ensuring consistency and security of data included in a block, and reducing pressure on a node of the data sharing system to store the shared data.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: October 6, 2020
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Rui Guo, Maocai Li, Jianjun Zhang, Haitao Tu, Qi Zhao, Zongyou Wang, Jun Liang, Dawei Zhu, Lisheng Chen, Binhua Liu
  • Patent number: 10785345
    Abstract: An information processing method, which is applied to a server, includes: a public message is transmitted to a first client, the public message being a message issued to the first client by the server, the public message carrying first information and a second information set including N pieces of second information, with N being a positive integer, the first information is information only allowed to be gotten by the first client and the second information is information only allowed to be gotten by a client in a sharing relationship with the first client; and a request for getting the second information is received from a second client, it is verified whether the second client is in the sharing relationship with the first client, and after the second client is determined to be in the sharing relationship with the first client, the second client is allowed to get the second information.
    Type: Grant
    Filed: August 15, 2017
    Date of Patent: September 22, 2020
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Xiaoyu Yu, Bin Zhang, Libin Ren, Wei Mao, Sixin Gu, Qiang Lu, Yongjie Li, Xuan Ye, Wenrui Zhang, Keren Li, Wenxin Liao, Jinming Zhang, Yi Gao, Boen Liang, Zeming Fan, Weizhao Li, Leming Fang, Tanhong Li, Guowei Xiang, Xinji Nie, Rui Tang, Haixia Rao, Feng Chen, Yi Wu, Chen Gong, Qianya Lin, Junbin Kuang, Siyu Xiao, Pengfei Wang, Leteng Weng, Xiaobin Fang, Mengsha Zhou, Zhenzhen Xu, Bei Yang, Shaomian Yao
  • Patent number: 10785038
    Abstract: A method for processing account information in a block chain is provided. A computer device receives identity information and a transfer request, the transfer request requesting to transfer a resource in an account to a target account, the target account being generated by a certificate center. The computer device obtains owner information of the account from the certificate center according to the transfer request. The computer device compares the identity information and the owner information. The computer device transmits an authentication request to the block chain in response to determining that the identity information and the owner information are consistent, the authentication request requesting the block chain to transfer the resource in the account to the target account.
    Type: Grant
    Filed: April 1, 2019
    Date of Patent: September 22, 2020
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LTD
    Inventors: Rui Guo, Mao Cai Li, Jian Jun Zhang, Hai Tao Tu, Qi Zhao, Zong You Wang, Jun Liang, Da Wei Zhu, Bin Hua Liu
  • Patent number: 10776939
    Abstract: Embodiments described herein provide various examples of an automatic obstacle avoidance system for unmanned vehicles using embedded stereo vision techniques. In one aspect, an unmanned aerial vehicle (UAV) capable of performing autonomous obstacle detection and avoidance is disclosed. This UAV includes: a stereo vision camera set coupled to the one or more processors and the memory to capture a sequence of stereo images; and a stereo vision module configured to: receive a pair of stereo images captured by a pair of stereo vision cameras; perform a border cropping operation on the pair of stereo images to obtain a pair of cropped stereo images; perform a sub sampling operation on the pair of cropped stereo images to obtain a pair of sub sampled stereo images; and perform a dense stereo matching operation on the pair of sub sampled stereo images to generate a dense three-dimensional (3D) point map of a space corresponding to the pair of stereo images.
    Type: Grant
    Filed: April 3, 2018
    Date of Patent: September 15, 2020
    Assignee: AltumView Systems Inc.
    Inventors: Rui Ma, Chao Shen, Yu Gao, Ye Lu, Minghua Chen, Jie Liang, Jianbing Wu
  • Patent number: 10766919
    Abstract: A class of polycyclic compounds of general formula (I), of general formula (I?), or of general formula (I?), wherein Base1, Base2, Y, Ya, Xa, Xa1, Xb, Xb1, Xc, Xc1, Xd, Xd1, R1, R1a, R2, R2a, R3, R4, R4a, R5, R6, R6a, R7, R7a, R8, and R8a are defined herein, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are processes for the synthesis and use of compounds.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: September 8, 2020
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Michael D. Altman, Brian Andresen, Wonsuk Chang, Matthew Lloyd Childers, Jared N. Cumming, Andrew Marc Haidle, Timothy J. Henderson, James P. Jewell, Rui Liang, Jongwon Lim, Hong Liu, Min Lu, Alan B. Northrup, Ryan D. Otte, Tony Siu, Benjamin Wesley Trotter, Quang T. Truong, Shawn P. Walsh, Kake Zhao
  • Publication number: 20200266052
    Abstract: Aspects of the disclosure provide a method including depositing an underlayer comprising silicon oxide over a substrate, depositing a polysilicon liner on the underlayer, and depositing an amorphous silicon layer on the polysilicon liner. Aspects of the disclosure provide a device intermediate including a substrate, an underlayer comprising silicon oxide formed over the substrate, a polysilicon liner disposed on the underlayer, and an amorphous silicon layer disposed on the polysilicon liner.
    Type: Application
    Filed: February 19, 2020
    Publication date: August 20, 2020
    Inventors: Krishna NITTALA, Rui CHENG, Karthik JANAKIRAMAN, Praket Prakash JHA, Jinrui GUO, Jingmei LIANG
  • Publication number: 20200259665
    Abstract: A transaction data processing method includes: receiving a first transaction document from a device of a transaction initiator, the first transaction document being associated with identity labels of a plurality of transaction participants; separately performing identity authentication on the plurality of transaction participants according to the identity labels of the plurality of transaction participants, to obtain an identity authentication result.
    Type: Application
    Filed: April 27, 2020
    Publication date: August 13, 2020
    Inventors: Rui GUO, Dongyan WANG, Maocai LI, Jun LIANG, Jianjun ZHANG, Zongyou WANG, Binhua LIU, Haitao TU, Qing QIN, Bo LI
  • Patent number: 10730849
    Abstract: Compounds of general formula (Ia), compounds of general formula (Ia?), compounds of general formula (Ib), compounds of general formula (Ib?), compounds of general formula (I), compounds of general formula (I?), and their pharmaceutically acceptable salts, wherein R1, R2, R3, R4, R5, R6, R8, R9, X1, X2, and X3 are defined herein, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are processes for the synthesis and use of compounds of the disclosure.
    Type: Grant
    Filed: July 16, 2019
    Date of Patent: August 4, 2020
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Michael D. Altman, Brandon D. Cash, Wonsuk Chang, Jared N. Cumming, Andrew M. Haidle, Timothy J. Henderson, James P. Jewell, Matthew A. Larsen, Rui Liang, Jongwon Lim, Min Lu, Ryan D. Otte, Tony Siu, Benjamin Wesley Trotter, Sriram Tyagarajan
  • Patent number: 10703738
    Abstract: Compounds of general formula (Ia), compounds of general formula (Ia?), compounds of general formula (Ib), compounds of general formula (Ib?), compounds of general formula (I), compounds of general formula (I?), and their pharmaceutically acceptable salts, wherein R1, R2, R3, R4, R5, R6, R8, R9, X1, X2, and X3 are defined herein, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are processes for the synthesis and use of compounds of the disclosure.
    Type: Grant
    Filed: July 16, 2019
    Date of Patent: July 7, 2020
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Michael D. Altman, Brandon D. Cash, Wonsuk Chang, Jared N. Cumming, Andrew M. Haidle, Timothy J. Henderson, James P. Jewell, Matthew A. Larsen, Rui Liang, Jongwon Lim, Min Lu, Ryan D. Otte, Tony Siu, Benjamin Wesley Trotter, Sriram Tyagarajan
  • Publication number: 20200189086
    Abstract: A power tool including a housing, a motor accommodated in the housing; and an output member connected to the motor via a transmission module. The transmission module is received in a substantially vacuum chamber in the housing. The vacuum chamber effectively reduces the propagation of noises generated by the transmission module to the outside of the power tool, thus improving the user experience.
    Type: Application
    Filed: September 6, 2018
    Publication date: June 18, 2020
    Inventors: Rui LIANG, Li Guo MA, Jing Feng ZHOU
  • Publication number: 20200089388
    Abstract: The present disclosure relates to methods and systems for providing a multimodal 3D object interaction to let the user interact with 3D digital object in a natural and realistic way.
    Type: Application
    Filed: December 21, 2018
    Publication date: March 19, 2020
    Inventors: Paul FU, Xiaohu DONG, Rui YANG, Chen ZHAO, JinRyong KIM, Xiangchao HUANG, Stephanie CHAN, Qing YU, Puhe LIANG, Shenli YUAN
  • Patent number: 10578675
    Abstract: The invention provides a method for estimating a battery capacity of an electronic device. When a current or an average current of the battery is zero, a reference capacity is inquired from a look-up table based on a voltage of the battery. When a previously remaining capacity is greater than a reference capacity, a deduction process of a self-consumable capacity is performed one or more times for a previously recorded remaining capacity to obtain a new recorded remaining capacity smaller than the reference capacity. When the current of the battery is less than zero, a deduction process of a count capacity of discharging is performed one or more times for the previously recorded remaining capacity until a power of the battery is exhausted to obtain a first offset capacity. The first offset capacity is deducted from a previously recorded full charge capacity to estimate a new full charge capacity.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: March 3, 2020
    Assignee: STL TECHNOLOGY CO., LTD.
    Inventor: Fang-Rui Liang
  • Patent number: 10568876
    Abstract: The present invention relates to a compound represented by formula (I): and pharmaceutically acceptable salts thereof. The compounds of formula (I) are inhibitors of diacylglyceride O-acyltransferase 2 (“DGAT2”) and may be useful in the treatment, prevention and suppression of diseases mediated by DGAT2. The compounds of the present invention may be useful in the treatment of hepatic steatosis, diabetes mellitus, obesity, hyperlipidemia, hypercholesterolemia, atherosclerosis, cardiorenal diseases such as chronic kidney diseases and heart failure and related diseases and conditions.
    Type: Grant
    Filed: August 31, 2015
    Date of Patent: February 25, 2020
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Jason Imbriglio, Rui Liang, Clare London, Kenneth Marby, James Tata, Ming You, Yusheng Xiong
  • Publication number: 20190363542
    Abstract: A method for wind power curtailment optimization comprises calculating the power flow for a power network for the day-ahead; calculating a contingency analysis for the power network for the day-ahead, comprising forecasted power generation, power consumption and topology of said power network, together with a set of contingency scenarios; calculating a sensitivity factor of a power flow for each power network branch to a power injection by each wind power plant, wherein the sensitivity factor is calculated only for the periods of time of the day-ahead for which overloaded branches have been detected during the solving of the power flow or during the solving of the contingency analysis; selecting a subset of the wind power plants having at least one sensitivity factor above a predetermined threshold as curtailment candidates; and calculating the wind power curtailment restricted to the selected subset of wind power plants.
    Type: Application
    Filed: August 14, 2017
    Publication date: November 28, 2019
    Inventors: Francisco Alexandre GANHO DA SILVA REIS, Rui PINTO QUÁDRIO ALVES, Caihao LIANG, Xiang ZUTAO
  • Publication number: 20190349188
    Abstract: Aspects of the disclosure provide methods and apparatuses for storing service data. In some examples, an apparatus for storing service data includes processing circuitry. The processing circuitry receives service data of a user and determines, in a plurality of blockchains, a target blockchain according to a user attribute of the user. Based on the service data and an eigenvalue of a block header of a first block in the target blockchain, the processing circuitry generates a second block in the target blockchain. The first block is a previous block of the second block. The second block is used for recording the service data.
    Type: Application
    Filed: July 26, 2019
    Publication date: November 14, 2019
    Applicant: Tencent Technology (Shenzhen) Company Limited
    Inventors: Rui GUO, Maocai LI, Jun LIANG, Jianjun ZHANG, Zongyou WANG, Qi ZHAO, Haitao TU, Binhua LIU, Dawei ZHU, Qing QIN
  • Publication number: 20190343971
    Abstract: The present invention provides a hexa-lactoside-triazanonane triacetic acid (NOTA) derivative, a method for radiolabeling a hexa-lactoside positron emission tomography (PET) imaging agent for a liver receptor with Ga-68, and a hexa-lactoside PET imaging agent for a liver receptor. The hexa-lactoside-NOTA derivative is a conjugate of six chains of lactose with NOTA obtained by conjugating hexa-lactoside to a chelating agent p-thiocyanate-benzyl-triazanonane diacetic acid-glutamic acid in the presence of triethyl amine/dimethyl formamide as a solvent. The radiolabeling method comprises labeling with Ga-68 at room temperature. According to the present invention, the labeling effect is stable, the labeling efficiency of the labeled product is greater than 95%, the labeled product is highly stable and the radiochemical purity is still greater than 90% after 4 hours.
    Type: Application
    Filed: November 27, 2018
    Publication date: November 14, 2019
    Inventors: Wuu-Jyh Lin, Mei-Hui Wang, Hung-Man Yu, Kun-Liang Lin, Yan-Feng Jiang, Rui-Yu Chen
  • Publication number: 20190347657
    Abstract: An apparatus including processing circuitry and a method are described. When receiving a cross-chain transaction request to transfer a resource from a first account to a second account, the processing circuitry is configured to generate a task corresponding to the first account. The task can indicate conditions for implementing events in transferring the resource. A first blockchain system provides services for the first account, and a second blockchain system different from the first blockchain system provides services for the second account. The processing circuitry transfers the resource to the second account based on the task when a first plurality of first nodes in the first blockchain system reaches a consensus on a generation event of the task and updates a task status of the task to being finished when a plurality of second nodes in the second blockchain system reaches a consensus on a transfer event of the resource.
    Type: Application
    Filed: July 26, 2019
    Publication date: November 14, 2019
    Applicant: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Rui GUO, Maocai LI, Jun LIANG, Jianjun ZHANG, Zongyou WANG, Haitao TU, Qi ZHAO, Binhua LIU, Dawei ZHU, Qing QIN
  • Publication number: 20190337917
    Abstract: Compounds of general formula (Ia), compounds of general formula (Ia?), compounds of general formula (Ib), compounds of general formula (Ib?), compounds of general formula (I), compounds of general formula (I?), and their pharmaceutically acceptable salts, wherein R1, R2, R3, R4, R5, R6, R8, R9, X1, X2, and X3 are defined herein, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are processes for the synthesis and use of compounds of the disclosure.
    Type: Application
    Filed: July 16, 2019
    Publication date: November 7, 2019
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: Michael D. Altman, Brandon D. Cash, Wonsuk Chang, Jared N. Cumming, Andrew M. Haidle, Timothy J. Henderson, James P. Jewell, Matthew A. Larsen, Rui Liang, Jongwon Lim, Min Lu, Ryan D. Otte, Tony Siu, Benjamin Wesley Trotter, Sriram Tyagarajan
  • Publication number: 20190342149
    Abstract: This application discloses a node device operation method, a work status switching apparatus, a node device, and a medium, and relates to the field of network technologies. The method includes: receiving voting requests of a plurality of node devices, a quantity of the plurality of node devices being greater than half a quantity of node devices in a system; obtaining cycle length information and latest log indexes from the voting requests of the plurality of node devices if a current node device operates in a leader state; and switching a current work status from the leader state to a follower state or a candidate state if all the cycle length information in the voting requests of the plurality of node devices is greater than cycle length information of the current node device and all the latest log indexes in the voting requests of the plurality of node devices are not less than a latest log index of the current node device.
    Type: Application
    Filed: July 12, 2019
    Publication date: November 7, 2019
    Inventors: Rui GUO, Maocai LI, Jun LIANG, Haitao TU, Qi ZHAO, Zongyou WANG, Jianjun ZHANG, Dawei ZHU, Binhua LIU