Abstract: This invention is benzothiophene-based estrogen receptor downregulators and their compositions and uses to treat estrogen-related medical disorders.

Abstract: Disclosed is a compound of formula (I). or a pharmaceutically acceptable salt thereof. Also disclosed are pharmaceutical compositions including the compound of formula (I) and methods of using the compound of formula (I).

Abstract: Compositions, combinations and methods comprising a CDK4/6 inhibitor of Formula D with a selective estrogen receptor downregulator of Formula A, B or C that are advantageous for the treatment of abnormal cellular proliferation, including a cancer or a tumor.

Abstract: This invention is benzothiophene-based selective mixed estrogen receptor downregulators and their compositions and uses to treat estrogen-related disorders.

Abstract: This invention is benzothiophene-based estrogen receptor downregulators and their compositions and uses to treat estrogen-related medical disorders.

Abstract: Disclosed herein are 18F-labeled compounds and compositions thereof. Also disclosed are methods of imaging estrogen receptor expressing tissues, or methods of identifying cancer lesions using these compounds.

Abstract: Disclosed is a compound of formula (I). or a pharmaceutically acceptable salt thereof. Also disclosed are pharmaceutical compositions including the compound of formula (I) and methods of using the compound of formula (I).

Abstract: This invention is benzothiophene-based estrogen receptor downregulators and their compositions and uses to treat estrogen-related medical disorders.

Abstract: Disclosed is a compound of formula (I). or a pharmaceutically acceptable salt thereof. Also disclosed are pharmaceutical compositions including the compound of formula (I) and methods of using the compound of formula (I).

Abstract: This invention is benzothiophene-based estrogen receptor downregulators and their compositions and uses to treat estrogen-related medical disorders.

Abstract: Ternary blends of rebaudioside B, rebaudioside D and rebaudioside M are provided. Quaternary blends of rebaudioside B, rebaudioside D, rebaudioside M and rebaudioside A are also provided. Sweetener compositions and consumables, particularly beverages and beverage products, comprising the ternary and quaternary blends are also provided. Methods of preparing consumables are also provided. The ternary and quaternary blends disclosed herein have improved sweetness profiles compared to certain blends of other steviol glycosides.

Abstract: This invention is benzothiophene-based estrogen receptor downregulators and their compositions and uses to treat estrogen-related medical disorders.

Abstract: This invention is benzothiophene-based estrogen receptor downregulators and their compositions and uses to treat estrogen-related medical disorders.

Abstract: Disclosed is a compound of formula (I). or a pharmaceutically acceptable salt thereof. Also disclosed are pharmaceutical compositions including the compound of formula (I) and methods of using the compound of formula (I).

Abstract: A method for estimating parameters and the state of a power system of an electric vehicle is disclosed. A multi-time scale model of the power system is set up; a parameter observer AEKF? based on a macroscopic time scale and a state observer AEKF, based on a microcosmic time scale in the power system of the electric vehicle are initialized; time update is performed on the parameter observer AEKF?, the updating time span is one macroscopic time scale, and a priori estimation value {circumflex over (?)}?l at the moment t1,0, of the parameter ? is obtained; time update and measurement update are performed on the state observer AEKFx and circulated for L times, so that the time of the state observer AEKFx is updated to the moment t0,1; and measurement update is performed on the parameter observer AEKF?, and the operation is circulated until the estimation is finished.

Abstract: In one embodiment, a method for deploying a data processing system in a virtual environment includes deploying a data processing system call interface in a virtual machine in a virtualization environment, the system call interface being configured to trigger a locally called data processing instruction. The method also includes deploying a data processing driver in a virtual machine management platform in the virtualization environment, the data processing driver being configured to read the data processing instruction triggered by the system call interface. Moreover, the method includes deploying a data processing instruction optimizer in the virtualization environment, the optimizer being configured to optimize the data processing instruction read by the deployed data processing driver.

Abstract: A method and apparatus for power-efficiency management in a virtualized cluster system. The virtualized cluster system includes a front-end physical host and at least one back-end physical host, and each of the at least one back-end physical host comprises at least one virtual machine and a virtual machine manager. Flow characteristics of the virtualized cluster system are detected at a regular time cycle, a power-efficiency management policy is generated for each of at least one back-end physical host based on the detected flow characteristics, and the power-efficiency management policies are performed.

Abstract: A method and apparatus for power-efficiency management in a virtualized cluster system. The virtualized cluster system includes a front-end physical host and at least one back-end physical host, and each of the at least one back-end physical host comprises at least one virtual machine and a virtual machine manager. Flow characteristics of the virtualized cluster system are detected at a regular time cycle, a power-efficiency management policy is generated for each of at least one back-end physical host based on the detected flow characteristics, and the power-efficiency management policies are performed.

Abstract: A method for realizing content sharing among mobile terminals comprises: receiving an index of access content sent by a requesting mobile terminal; looking up a shareable content index table for the index of the access content; and sending identification information of a mobile terminal having the index of the access content to the requesting mobile terminal if the index of the access content is found, so that the requesting mobile terminal obtains the requested access content from the mobile terminal having the index of the access content via wireless communication.

Abstract: Embodiments of the present invention relate to a method and apparatus for determining the location of a mobile device. Specifically, the method comprises: receiving the location message from a neighboring mobile device, the location message comprising the location of the neighboring mobile device at the current time which is obtained by the neighboring mobile device through calculation utilizing signals received from satellites; and estimating the location of the mobile device at the current time based on stored locations of the mobile device at historical time, stored locations of the neighboring mobile device at the historical time, and the received location of the neighboring mobile device at the current time.