Abstract: Apparatus and associated methods relate to a catheter manipulation handle with user interface controls for steering a catheter in situ while providing an augmented (e.g., motorized, powered and tunable precision steering, and perforation safeguards) control and feedback user experience. In an illustrative example, the catheter manipulation handle may provide motor assisted operation to automatically rotate and/or deflect a distal tip of the catheter to steer and guide the distal tip to a target location in the patient's vasculature system. The augmented feedback may include, for example, haptic feedback via the handle. Haptic, audible, and/or visual feedback via the handle may indicate, for example, proximity or engagement of the distal tip with sensitive tissue. In some examples, the handle's augmented operation may advantageously amplify feedback signals to enhance the user's perception of the patient's safety with respect to the safe passage of the distal tip through the patient's vasculature.

Abstract: An apparatus can include a housing defining a housing interior, an air pump positioned in the housing interior, and a plurality of resilient connectors connecting the air pump to the housing with the resilient connectors in tension so as to reduce transmission of vibration from the air pump to the housing during operation of the air pump.

Abstract: The present disclosure provides a system and method for efficiently mining multi-threshold measurements acquired using photon counting pixel-array detectors for spectral imaging and diffraction analyses. Images of X-ray intensity as a function of X-ray energy were recorded on a 6 megapixel X-ray photon counting array detector through linear fitting of the measured counts recorded as a function of counting threshold. An analytical model is disclosed for describing the probability density of detected voltage, utilizing fractional photon counting to account for edge/corner effects from voltage plumes that spread across multiple pixels. Three-parameter fits to the model were independently performed for each pixel in the array for X-ray scattering images acquired for 13.5 keV and 15.0 keV X-ray energies. From the established pixel responses, multi-threshold composite images produced from the sum of 13.5 keV and 15.

Abstract: Apparatus and associated methods relate to a solenoid assisted valve including a split collar and a precision sealing valve seat surface with tight dimensional tolerances and substantial performance repeatability. In an illustrative example, the split collar may concentrically mate around a cylindrical bobbin. In some examples, the split collar may include ferromagnetic material alone or in combination with various thermoplastic materials. The placement of the split collar may be adjusted by manufacturing to fine tune placement of a magnetic pole and to customize valve performance, for example. The valve seat may include, for example, an orifice sealed with an elastic stopper. The valve seat may be configured, for example, with specific ratiometric dimensional relationships and flatness specifications. Various solenoid valves may allow manufacturers to tune the location of a solenoid generated magnetic pole, for example, to tailor the valve plunger performance for a wide variety of applications.

Abstract: A modular tire service station for servicing vehicle tires includes a first pre-configured service module and a second pre-configured service module that is proximate the first module. A customer area is disposed in at least one of the first module and the second module, a tire storage area is disposed in at least one of the first module and the second module, and a tire service area is disposed in at least one of the first module and the second module.

Abstract: A system and method for providing original equipment manufacturer (OEM) control to maximize profits that include determining at least one demand based charging schedule and processing an OEM charging policy option to schedule charging of the at least one electric vehicle at a low energy production cost timeframe. The system and method also include modifying the at least one demand based charging schedule into a policy based charging schedule based on an acceptance of the OEM charging policy option by the at least one utility provider. The system and method further include facilitating payment of an incentive fee from the at least one utility provider to the OEM.

Abstract: A modular tire service station for servicing vehicle tires includes a first pre-configured service module and a second pre-configured service module that is proximate the first module. A customer area is disposed in at least one of the first module and the second module, a tire storage area is disposed in at least one of the first module and the second module, and a tire service area is disposed in at least one of the first module and the second module.

Abstract: A modular tire service station for servicing vehicle tires includes a first pre-configured service module and a second pre-configured service module that is proximate the first module. A customer area is disposed in at least one of the first module and the second module, a tire storage area is disposed in at least one of the first module and the second module, and a tire service area is disposed in at least one of the first module and the second module.

Abstract: A modular tire service station for servicing vehicle tires includes a first pre-configured service module and a second pre-configured service module that is proximate the first module. A customer area is disposed in at least one of the first module and the second module, a tire storage area is disposed in at least one of the first module and the second module, and a tire service area is disposed in at least one of the first module and the second module.

Abstract: A fleet management system includes a request component that receives one or more service requests and analyzes a first service request to identify a plurality of request parameters, a fuel component that identifies one or more fuel parameters associated with the fuel types, an evaluation component that analyzes a plurality of service parameters in light of the request parameters and the fuel parameters to determine a plurality of operating costs for managing the first service request, and a service component that analyzes the operating costs to select a first vehicle type corresponding to one of the operating costs for managing the first service request. The fleet management system enables a fleet of vehicles using a plurality of fuel types to be effectively and efficiently managed.

Abstract: A fleet management system includes a market component that monitors a hydrogen market and identifies one or more hydrogen parameters associated with the hydrogen market, an electric vehicle component that analyzes the hydrogen parameters and selectively instructs one or more electric vehicles to provide electricity for generating hydrogen based on the hydrogen parameters, and a hydrogen vehicle component that selectively instructs one or more hydrogen vehicles to obtain at least a portion of the hydrogen generated from the electricity provided by the electric vehicles. The fleet management system enables a fleet of vehicles using a plurality of fuel types to be effectively and efficiently managed. Moreover, the fleet management system allows a hydrogen economy to grow in an economical and pragmatic manner.

Abstract: Apparatus and associated methods relate to a wearable compression therapy system for ambulatory therapy, the system including a wearable garment having one or more inflatable chambers, and a pneumatic engine locally coupled to the garment to provide control and inflation of the one or more inflatable chambers. In an illustrative embodiment, the pneumatic engine may control a pump and one or more valves to inflate the inflatable chambers. The valves and pump may be coordinated according to a pre-programmed profile. In some embodiments, the pneumatic engine may have a wireless interface configured to receive control signals from a remote mobile device untethered from the garment. The pneumatic engine may send to the remote mobile device signals indicative of sensed conditions of the compression therapy system. In some embodiments, the pneumatic engine may include a power source that advantageously permits the user to be untethered from a source of power.

Abstract: Autonomous machine navigation techniques may generate a three-dimensional point cloud that represents at least a work region based on feature data and matching data. Pose data associated with points of the three-dimensional point cloud may be generated that represents poses of an autonomous machine. A boundary may be determined using the pose data for subsequent navigation of the autonomous machine in the work region. Non-vision-based sensor data may be used to determine a pose. The pose may be updated based on the vision-based pose data. The autonomous machine may be navigated within the boundary of the work region based on the updated pose. The three-dimensional point cloud may be generated based on data captured during a touring phase. Boundaries may be generated based on data captured during a mapping phase.

Abstract: Apparatus and methods are directed to virtually verifying authenticity of medical information transmitted from at least one unvalidated communication device associated with a patient being monitored by at least on validated medical device. In an illustrative example, medical information related to patient data may be transmitted through a network for storage in a central database from one or more validated medical devices and one or more unvalidated personal communication devices. The transmitted information may include unique identifiers that enables the patient data to be verified and collated across the validated and unvalidated devices and assigned to a specific data record for a given patient or group of patients.

Abstract: Methods and systems are described herein for small molecule biochemical profiling of an individual subject for diagnosis of a disease or disorder, facilitating diagnosis of a disease or disorder, and/or identifying an increased risk of developing a disease or disorder in the individual subject. Aberrant levels of small molecules present in a sample from an individual subject are identified and diagnostic information relevant to the individual subject is obtained based on the identified aberrant levels. The obtained diagnostic information includes one or more of an identification of at least one biochemical pathway associated with the identified subset of the small molecules having aberrant levels, an identification at least one disease or disorder associated with the identified subset of the small molecules having aberrant levels, and an identification of at least one recommended follow up test associated with the identified subset of the small molecules having aberrant levels.

Abstract: Apparatus and associated methods relate to a wearable compression therapy system for ambulatory therapy, the system including a wearable garment having one or more inflatable chambers, and a pneumatic engine locally coupled to the garment to provide control and inflation of the one or more inflatable chambers. In an illustrative embodiment, the pneumatic engine may control a pump and one or more valves to inflate the inflatable chambers. The valves and pump may be coordinated according to a pre-programmed profile. In some embodiments, the pneumatic engine may have a wireless interface configured to receive control signals from a remote mobile device untethered from the garment. The pneumatic engine may send to the remote mobile device signals indicative of sensed conditions of the compression therapy system. In some embodiments, the pneumatic engine may include a power source that advantageously permits the user to be untethered from a source of power.

Abstract: Apparatus and associated methods relate to a risk trace matrix engine for managing database associations, in a quality management system (QMS), between risk mitigations and features of a system having a risk-based profile. In an illustrative example, metadata may be created to associate risk mitigations with elements of a product and then metadata may be stored in a database during the design or operating lifecycle of the product, for example. The engine may dynamically build one or more trace matrices for the product design, each matrix associating risk mitigations to elements of the product design documentation. In response to any modifications that may relate to the component's specifications, for example, the engine may retrieve associated metadata and generate notifications prompting for user verification.

Abstract: Apparatus and methods relate to a pneumatic compression therapy device configured to suggest content to the patient based on a determined disease state, the content pertaining to suggested changes in lifestyle based on a standard of care. In an illustrative embodiment, the suggested changes may include modifications to treatment location, treatment time, diet, eating habits, or sleeping schedule. Various examples may further sample the patient's health and automatically adjust a treatment parameter within a predetermined parameter range based on a history of measured parameters, such as limb volume, for example. In coordination with the therapeutic treatment, the therapy device may deliver suggested content to guide the patient to make more healthful lifestyle choices to reduce recovery time and improve patient health outcomes.

Abstract: A quantitative optical microscopy arrangement is described. Specifically, a digital filter derived from linear discriminant analysis is described for recovering impulse responses in applications that may include photon counting from a high speed photodetector and applied to remove ringing distortions from impedance mismatch in multiphoton fluorescence microscopy. Training of the digital filter is achieved by defining temporally coincident and non-coincident transients and identifying the projection within filter-space that best separates the two classes. The training allows rapid data analysis by digital filtering. The LDA filter is also capable of recovering deconvolved impulses for single photon counting from highly distorted ringing waveforms from an impedance mismatched photomultiplier tube.

Abstract: A beam-scanning optical design is described for achieving up to kHz frame-rate optical imaging on multiple simultaneous data acquisition channels. In one embodiment, two fast-scan resonant mirrors direct the optical beam on a circuitous trajectory through the field of view, with the trajectory repeat-time given by the least common multiplier of the mirror periods. Dicing the raw time-domain data into sub-trajectories combined with model-based image reconstruction (MBIR) 3D in-painting algorithms allows for effective frame-rates much higher than the repeat time of the Lissajous trajectory. Because sub-trajectory and full-trajectory imaging are different methods of analyzing the same data, both high-frame rate images with relatively low resolution and low frame rate images with high resolution are simultaneously acquired.