Abstract: The present disclosure provides a physical quantity detection device and a signal processing device capable of improving accuracy in detecting an air flow rate by a thermal flow sensor during pulsation of air including a reverse flow region. The signal processing device 200 includes a direction determination unit 210, an increase/decrease determination unit 220, a correction factor storage unit 230, a correction factor selection unit 240, and a signal correction unit 250. The direction determination unit 210 determines a forward flow or a reverse flow of the air based on a detection signal DS of the thermal flow sensor. The increase/decrease determination unit 220 determines an increase or decrease in flow rate of the air based on the detection signal DS. The correction factor storage unit 230 stores first to fourth factors used for correction of the detection signal DS.

Abstract: A fixing unit or device that can be used in an image forming apparatus includes a first heater element that is formed of a material that increases in electrical resistance with increases in temperature. A controller of the fixing unit is configured to vary a duty ratio of electric power applied to the first heater element during a start-up operation in which the temperature of the first heater element is raised to a target operating temperature. By varying the duty ratio during the start-up operation, changes in the resistance of the first heater element with the heating can be compensated. For example, the duty ratio can be increased during the course of the start-up to achieve the target operating temperature faster.

Abstract: To provide a cuff for measuring blood pressure which is excellent in durability and convenient to use. A cuff for measuring blood pressure includes a band enveloping an air bag between an outer cloth and an inner cloth facing the outer cloth; a first opening portion provided in the outer cloth; and a first hook-and-loop fastener welded to the outer cloth in a state where the first opening portion is closed from an inner side of the band and a raised surface is exposed through the first opening portion.

Abstract: Provided is a convenient blood pressure cuff. A blood pressure cuff includes a band-like body enveloping an air bag between an outer cloth and an inner cloth facing the outer cloth; a ring-like member held at a position near one end edge it in a longitudinal direction of the band-like body and extending in a lateral direction of the band-like body; and an auxiliary member stored inside a terminal region between the end edge it of the band-like body and the ring-like member and extending in the lateral direction. The outer cloth and the inner cloth in the terminal region are welded to each other in a state where the auxiliary member is sandwiched between the outer cloth and the inner cloth.

Abstract: A blood pressure monitor cuff is formed by stacking an outer circumferential layer arranged on a side opposite to that of a measurement site and a fluid bladder arranged on the measurement site side. The outer circumferential layer and the fluid bladder are formed of an elastomer material. Two edge portions in a lengthwise direction of the outer circumferential layer protrude in a thickness direction toward the measurement site. The fluid bladder includes a base layer that opposes the outer circumferential layer and a top layer overlapping with the base layer, and the edge portions of the base layer and the top layer are welded together forming a bladder shape. Additional sheets are welded in the thickness direction to the welded edge portions of the top layer and the base layer. The fluid bladder is arranged between the two edge portions of the outer circumferential layer in the width direction.

Abstract: A blood pressure measurement method includes wrapping a cuff around a site. The cuff includes: a first bladder that swells due to receiving fluid and is arranged at an outer surface of the site that corresponds to a first half surface where an artery is; and a second bladder that swells due to receiving fluid and is arranged at the outer circumferential surface of the measurement site that corresponds to a second half surface opposite to the first half surface. During inflation, the pressure of the second bladder is made larger than the first bladder by supplying more fluid such that the stroke amount by which the second fluid bladder swells is larger in the thickness direction. Then, the two bladders are inflated at equal rates. In the process of inflating, or in the process of deflating at rates equal to each other after inflating, blood pressure is measured.

Abstract: Methods and compositions are provided herein that pertain to the discovery that the crystallin alpha B (CRYAB) gene and gene product provides an effective target for senolytic agents. In certain embodiments, methods of selectively killing one or more senescent cells in a subject in need thereof are provided wherein the method involves administering to the subject an effective amount of an agent that inhibits expression and/or aggregation of a CRYAB protein.

Abstract: A thermal airflow sensor includes a sensor element, a bonding wire, a resin, and a protective film. The sensor element has a thin-wall portion. The thin-wall portion has a heating resistor. The bonding wire is electrically connected to the sensor element. The resin covers the bonding wire. The protective film is formed on a surface of the sensor element so that the heating resistor is exposed. The protective film has at least a slit between the resin and the thin-wall portion.

Abstract: A blood pressure measurement cuff includes a belt-like body including an outer fabric and an inner fabric facing each other to form a bag shape, the belt-like body housing a fluid bag, an elliptical ring member having one side attached to a region adjacent to one end of the belt-like body, a retaining member provided to a region adjacent to the other end of the belt-like body, and a fixing member provided to a front surface of the outer fabric of the belt-like body. The retaining member includes a projection part that is flexible and projects outward of the belt-like body in a thickness direction Z, and support parts, each being flat plate-like, contiguous with a base of the projection part, and attached along the region adjacent to the other end of the outer fabric.

Abstract: A fluid bladder includes multiple segment bladders that are each formed by folding one sheet in half in a width direction X extending along an artery passing through the measurement site, welding or adhering edge portions on a side opposite to the folding location for folding in half, and welding or adhering edge portions in a lengthwise direction Y. The multiple segment bladders are stacked in a width direction orthogonal to the measurement site and integrated, and the folding locations are arranged alternatingly on opposite sides in the width direction.

Abstract: The purpose of the present invention is to provide a water-in-oil emulsion cosmetic that, while having an excellent hair-styling effect, exhibits a strong ability to moisturize the coated tissue, provides a smooth finger manipulation sense unlike that of a cream or wax, and does not produce stickiness on the hands and hair. The water-in-oil emulsion cosmetic according to the present invention is characterized by containing (A) a crosslinked siloxane elastomer, (B) a solid oil component, (C) a liquid oil component, and (D) at least 55 mass % water, wherein the ratio of component (B) to component (C) ((B)/(C)) is 0.25 to 1.5.

Abstract: The present invention has been made to improve measurement accuracy of a thermal flow meter. In the thermal flow meter according to the invention, a circuit package (400) that measures a flow rate is molded in a first resin molding process. In a second resin molding process, a housing (302) having an inlet trench (351), a bypass passage trench on frontside (332), an outlet trench (353), and the like are formed through resin molding, and an outer circumferential surface of the circuit package (400) produced in the first resin molding process is enveloped by a resin in the second resin molding process to fix the circuit package (400) to the housing (302).

Abstract: An appliance includes a belt that is worn by being wound around a wrist. The appliance includes: at least a first display region that is positioned in an area of the belt that corresponds to a volar-side surface or a radius-side surface of the wrist; and a second display region that is positioned in an area of the belt that corresponds to a back-side surface of the wrist. During a blood pressure measurement period, first control for displaying ongoing blood pressure measurement information only on the first display region is performed, and during a period other than the blood pressure measurement period, second control for displaying information that needs to be displayed on the first or second display region is performed.

Abstract: The present invention has been made to improve measurement accuracy of a thermal flow meter. In the thermal flow meter according to the invention, a circuit package (400) that measures a flow rate is molded in a first resin molding process. In a second resin molding process, a housing (302) having an inlet trench (351), a bypass passage trench on frontside (332), an outlet trench (353), and the like are formed through resin molding, and an outer circumferential surface of the circuit package (400) produced in the first resin molding process is enveloped by a resin in the second resin molding process to fix the circuit package (400) to the housing (302).

Abstract: In order to provide a flow measuring device high in thermal responsiveness, the flow measuring device includes a temperature detecting element 2 for temperature detection, and a conductive metal lead frame 3 that supports and fixes the temperature detecting element. Of the metal lead frame, a part of the metal lead frame mounted with the temperature detecting element has a portion which is thinner than the thickness of the other metal lead frame or narrower than the width of the other metal lead frame.

Abstract: The present invention has been made to improve measurement accuracy of a thermal flow meter. In the thermal flow meter according to the invention, a circuit package (400) that measures a flow rate is molded in a first resin molding process. In a second resin molding process, a housing (302) having an inlet trench (351), a bypass passage trench on frontside (332), an outlet trench (353), and the like are formed through resin molding, and an outer circumferential surface of the circuit package (400) produced in the first resin molding process is enveloped by a resin in the second resin molding process to fix the circuit package (400) to the housing (302).

Abstract: A thermal flowmeter circuit package having a side of a measurement surface 430 of the circuit package and a flow path 387 at a side of the backside of measurement surface 431 of a rear surface of the measurement surface 430, and an inflow-side end surface of the circuit package for dividing the measurement target gas 30 has different shapes at the side of the measurement surface and at the side of the backside of measurement surface. The inflow-side end surface of the circuit package for dividing the measurement target gas 30 is formed with a reference line 700 dividing the measurement target gas 30, and an end surface 701a at the side of the measurement surface with respect to the reference line and an end surface 701b at the side of the backside of measurement surface with respect to the reference line are formed to be asymmetrical.

Abstract: A blood pressure measurement method includes wrapping a cuff around a site. The cuff includes: a first bladder that swells due to receiving fluid and is arranged at an outer surface of the site that corresponds to a first half surface where an artery is; and a second bladder that swells due to receiving fluid and is arranged at the outer circumferential surface of the measurement site that corresponds to a second half surface opposite to the first half surface. During inflation, the pressure of the second bladder is made larger than the first bladder by supplying more fluid such that the stroke amount by which the second fluid bladder swells is larger in the thickness direction. Then, the two bladders are inflated at equal rates. In the process of inflating, or in the process of deflating at rates equal to each other after inflating, blood pressure is measured.

Abstract: Degradation of reliability of a thermal fluid flow sensor, caused by generation of a crack in an insulating film is prevented in the thermal fluid flow sensor including a detection section and a circuit section formed on the same substrate when stress adjustment is performed by forming a deep concave portion in an interlayer insulating film in the detection section and forming the insulating film having a tensile stress thereon. As a means thereof, stair-like step is provided in a side wall of a concave portion, formed in the interlayer insulating film on a diaphragm. Accordingly, each depth of a first concave portion and a second concave portion, which form the concave portion, is reduced, and coatability of the insulating film for the stress adjustment, which covers a side wall and a bottom face of the concave portion, is improved.

Abstract: A fluid bladder has a first fluid bladder region that inflates due to receiving a supply of fluid and is contained in a portion of an outer circumferential surface of a measurement site in a lengthwise direction of a cuff, the portion corresponding to a first half surface, where an artery is. Also, the fluid bladder has an expansion region that is expanded due to an action from outside, and is contained at a portion of the outer circumferential surface of the measurement site that corresponds to a second half surface, in the lengthwise direction of the cuff. During inflation for blood pressure measurement, a stroke amount by which the expansion region expands is larger in the thickness direction than a stroke amount by which the first fluid bladder region swells.