Patents by Inventor Ryuji Hashimoto

Ryuji Hashimoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11114071
    Abstract: Provided is a percussion instrument including a substantially cylindrical barrel and a weight fixed to the barrel. More specifically, a plurality of weights 5A to 5D may be provided on the inner circumferential surface of a shell 2 of a drum 1 (a percussion instrument). The weights 5A to 5D may be provided at positions where the weights 5A to 5D have four-fold rotational symmetry in the circumferential direction of the shell 2. The weights 5A to 5D may be each provided between lugs 3 that are provided adjacent to each other on the outer circumferential surface of the shell 2.
    Type: Grant
    Filed: April 29, 2019
    Date of Patent: September 7, 2021
    Assignee: YAMAHA CORPORATION
    Inventors: Ryuji Hashimoto, Noritaka Nagai, Banri Abe
  • Patent number: 11081265
    Abstract: A rare-earth sintered magnet contains main phase crystal grains having an Nd5Fe17-type crystal structure, includes R and T (where R represents one or more rare-earth elements that essentially include Sm and T represents Fe or one or more transition metal elements that essentially include Fe and Co), and wherein the compositional ratio of R is 20-40 at % and the remaining portion is substantially T; the remaining portion other than R is substantially only T or only T and C; and when the main phase crystal grains' average grain size in one cross-sectional surface of the rare-earth sintered magnet is defined as Dv, while grain size of individual main phase crystal grains is defined as Di, Dv is at least 1.0 ?m, and the main phase crystal grains' area ratio that satisfy 0.7Dv?Di?2.0Dv is at least 80% with respect to the area of a cross-sectional surface of the rare-earth sintered magnet.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: August 3, 2021
    Assignee: TDK CORPORATION
    Inventors: Takurou Iwasa, Ryuji Hashimoto, Masashi Ito
  • Patent number: 11034737
    Abstract: The present disclosure provides hNGAL muteins that bind CGRP and can be used in various application including pharmaceutical applications, for example, migraine. The present disclosure also concerns methods of making one or more muteins described herein as well as compositions and combinations comprising one or more of such muteins. The present disclosure further relates to nucleic acid molecules encoding such muteins and to methods for generation of such muteins and nucleic acid molecules. In addition, the application discloses therapeutic and/or diagnostic uses of these muteins as well as compositions and combinations comprising one or more of such muteins.
    Type: Grant
    Filed: July 8, 2019
    Date of Patent: June 15, 2021
    Assignee: Pieris Pharmaceuticals GmbH
    Inventors: Gabriele Matschiner, Christine Rothe, Alexander Wiedenmann, Rachida Siham Bel Aiba, Marlon Hinner, Andrea Allersdorfer, Bradley Lunde, Kazufumi Kubota, Mitsuhiro Makino, Sakiko Takahashi, Ryuji Hashimoto, Tohru Takahashi, Mamoru Otoyo
  • Publication number: 20210082605
    Abstract: One embodiment of the present invention includes, in a samarium-iron-nitrogen based magnet powder, a main phase containing samarium and iron, and a sub-phase containing samarium, iron, and at least one or more elements selected from the group consisting of zirconium, molybdenum, vanadium, tungsten, and titanium, wherein an atomic ratio of a rare earth element to an iron group element is greater than an atomic ratio of the rare earth element to the iron group element of the main phase, wherein at least a part of a surface of the main phase is coated with the sub-phase.
    Type: Application
    Filed: March 27, 2019
    Publication date: March 18, 2021
    Applicant: TDK Corporation
    Inventors: Ryuji HASHIMOTO, Yasushi ENOKIDO, Shusuke OKADA, Kenta TAKAGI
  • Publication number: 20210043344
    Abstract: A permanent magnet including R and T. R are rare earth elements including Sm and at least one selected from Y and Gd. T is Fe alone or Fe and Co. T maybe partly substituted with M, and M is one or more selected from Ti, V, Cr, Mo, W, Zr, Hf, Nb, Ta, Al, Si, Cu, Zn, Ga and Ge. In a total content of R, Sm content is 60 at % or more and 95 at % or less, and a total content of Y and Gd is 5 at % or more and 35 at % or less. The permanent magnet includes main phase crystal grains having a ThMn12 type crystal structure.
    Type: Application
    Filed: January 29, 2019
    Publication date: February 11, 2021
    Applicant: TDK CORPORATION
    Inventors: Masaki TOMITA, Ryuji HASHIMOTO, Takashi WATANABE
  • Publication number: 20200377573
    Abstract: It is intended to provide a novel peptide. The present invention provides a peptide which comprises the amino acid sequence shown in SEQ ID NO: 30 and inhibits protease activity.
    Type: Application
    Filed: December 21, 2017
    Publication date: December 3, 2020
    Applicant: DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Daisuke Nishimiya, Ryuji Hashimoto, Toshiyuki Sato, Takako Kimura, Atsushi Yamasaki, Tatsuya Inoue
  • Publication number: 20200231654
    Abstract: The present invention provides a novel peptide that has an amino acid sequence represented by SEQ ID NO: 18, and binds to an active protease but does not bind to a pro-protease.
    Type: Application
    Filed: July 17, 2018
    Publication date: July 23, 2020
    Applicant: Daiichi Sankyo Company, Limited
    Inventors: Hidenori Yano, Daisuke Nishimiya, Ryuji Hashimoto, Yoichi Niitsu
  • Publication number: 20200199179
    Abstract: Disclosed are compositions and method related to variants of SPINK2 that bind to targets other than an endogenous target of SPINK2. In one embodiment, a peptide is provided that comprises the amino acid sequence SEQ ID NO: 1. In further embodiments, an amino acid sequences encoded by nucleotide positions 4 to 42 and/or nucleotide positions 94 to 189 in the nucleotide sequence of SEQ ID NO: 14 flank the amino terminus and the carboxyl terminus, respectively, of the amino acid sequence. In another embodiment, a peptide is provided that comprises an amino acid sequence derived from the amino acid sequence of SEQ ID NO: 1 in which a conservative substitution, deletion, addition and/or insertion of 1 to 5 (inclusive) amino acids has occurred at amino acids other than the 1st Xaa to the 12th Xaa counting from the amino terminus.
    Type: Application
    Filed: January 30, 2020
    Publication date: June 25, 2020
    Applicant: Daiichi Sankyo Company, Limited
    Inventors: Daisuke Nishimiya, Ryuji Hashimoto
  • Publication number: 20200118722
    Abstract: One embodiment of the present invention is that in samarium-iron-nitrogen magnet powder, a non-magnetic phase is formed on a surface of the samarium-iron-nitrogen magnet phase, and an arithmetic mean roughness Ra of the surface is 3.5 nm or less.
    Type: Application
    Filed: May 29, 2018
    Publication date: April 16, 2020
    Applicants: National Institute of Advanced Industrial Science and Technology, TDK Corporation
    Inventors: Shusuke OKADA, Kenta TAKAGI, Yasushi ENOKIDO, Yoshinori FUJIKAWA, Ryuji HASHIMOTO
  • Publication number: 20200105446
    Abstract: A samarium-iron-bismuth-nitrogen-based magnet powder includes: a main phase including samarium, iron, and bismuth, wherein a ratio of bismuth to a total amount of samarium, iron, and bismuth is less than or equal to 3.0 at %.
    Type: Application
    Filed: September 25, 2019
    Publication date: April 2, 2020
    Applicants: TDK Corporation, National Institute of Advanced Industrial Science and Technology
    Inventors: Ryuji HASHIMOTO, Yasushi Enokido, Shusuke Okada, Kenta Takagi
  • Patent number: 10550154
    Abstract: Disclosed are compositions and method related to variants of SPINK2 that bind to targets other than an endogenous target of SPINK2. In one embodiment, a peptide is provided that comprises the amino acid sequence SEQ ID NO: 1. In further embodiments, an amino acid sequences encoded by nucleotide positions 4 to 42 and/or nucleotide positions 94 to 189 in the nucleotide sequence of SEQ ID NO: 14 flank the amino terminus and the carboxyl terminus, respectively, of the amino acid sequence. In another embodiment, a peptide is provided that comprises an amino acid sequence derived from the amino acid sequence of SEQ ID NO: 1 in which a conservative substitution, deletion, addition and/or insertion of 1 to 5 (inclusive) amino acids has occurred at amino acids other than the 1st Xaa to the 12th Xaa counting from the amino terminus.
    Type: Grant
    Filed: August 7, 2013
    Date of Patent: February 4, 2020
    Assignee: Daiichi Sankyo Company, Limited
    Inventors: Daisuke Nishimiya, Ryuji Hashimoto
  • Publication number: 20200020468
    Abstract: To provide a rare earth permanent magnet having as a main phase a compound with a Nd5Fe17 crystalline structure having strong coercive force. A rare earth permanent magnet having as a main phase a compound with a Nd5Fe17 crystalline structure, wherein when the composition ratio of the rare earth permanent magnet is expressed as RaT(100-a-b)Cb, where R is one or more rare earth elements requiring Sm, and T is one or more transition metal elements requiring Fe or Fe and Co, a and b satisfy 18<a<40 and 0.5?b, and a phase where R and C are denser than the main phase is provided in the grain boundary phase of the rare earth permanent magnet.
    Type: Application
    Filed: November 30, 2017
    Publication date: January 16, 2020
    Applicant: TDK CORPORATION
    Inventors: Ryuji HASHIMOTO, Masashi ITO, Eiichiro FUKUCHI, Yuki NAGAMINE
  • Patent number: 10529474
    Abstract: To provide a permanent magnet which uses Ce of an abundant resource and has a great magnetic anisotropy in rare earth permanent magnets. To obtain a permanent magnet having a high magnetic anisotropy due to the trivalent Ce state by setting the abundance ratio C3/(C3+C4) in the main phase grains to be 0.1?C3/(C3+C4)?0.5 where C3 denotes the number of trivalent Ce atoms and C4 denotes the number of tetravalent Ce atoms.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: January 7, 2020
    Assignee: TDK CORPORATION
    Inventors: Shogo Kadota, Kenichi Suzuki, Yuji Umeda, Ryuji Hashimoto, Keiji Takeda
  • Publication number: 20200005973
    Abstract: A rare-earth sintered magnet contains main phase crystal grains having an Nd5Fe17-type crystal structure, includes R and T (where R represents one or more rare-earth elements that essentially include Sm and T represents Fe or one or more transition metal elements that essentially include Fe and Co), and wherein the compositional ratio of R is 20-40 at % and the remaining portion is substantially T; the remaining portion other than R is substantially only T or only T and C; and when the main phase crystal grains' average grain size in one cross-sectional surface of the rare-earth sintered magnet is defined as Dv, while grain size of individual main phase crystal grains is defined as Di, Dv is at least 1.0 ?m, and the main phase crystal grains' area ratio that satisfy 0.7Dv?Di?2.0Dv is at least 80% with respect to the area of a cross-sectional surface of the rare-earth sintered magnet.
    Type: Application
    Filed: November 30, 2017
    Publication date: January 2, 2020
    Applicant: TDK CORPORATION
    Inventors: Takurou IWASA, Ryuji HASHIMOTO, Masashi ITO
  • Patent number: 10497343
    Abstract: A reed includes: a reed main body having a plate shape, the reed main body including a fixed part fixed to a mouthpiece, and a vibrating part that extends from the fixed part and vibrates; and a sensor part that is disposed inside the vibrating part or on an inner surface of the vibrating part, the inner surface of the vibrating part facing the mouthpiece, the sensor part comprising an effective sensor portion that detects vibration of the vibrating part.
    Type: Grant
    Filed: August 29, 2018
    Date of Patent: December 3, 2019
    Assignee: Yamaha Corporation
    Inventors: Ryuji Hashimoto, Ryo Shinoda
  • Publication number: 20190338002
    Abstract: The present disclosure provides hNGAL muteins that bind CGRP and can be used in various application including pharmaceutical applications, for example, migraine. The present disclosure also concerns methods of making one or more muteins described herein as well as compositions and combinations comprising one or more of such muteins. The present disclosure further relates to nucleic acid molecules encoding such muteins and to methods for generation of such muteins and nucleic acid molecules.
    Type: Application
    Filed: July 8, 2019
    Publication date: November 7, 2019
    Inventors: Gabriele Matschiner, Christine Rothe, Alexander Wiedenmann, Rachida Siham Bel Aiba, Marlon Hinner, Andrea Allersdorfer, Bradley Lunde, Kazufumi Kubota, Mitsuhiro Makino, Sakiko Takahashi, Ryuji Hashimoto, Tohru Takahashi, Mamoru Otoyo
  • Publication number: 20190295516
    Abstract: A drum head includes: a head portion in which an opening is formed along a periphery of the head portion; and a protective skin closing the opening and having air permeability.
    Type: Application
    Filed: September 14, 2016
    Publication date: September 26, 2019
    Inventors: Ryuji HASHIMOTO, Eiji ABE
  • Patent number: 10403248
    Abstract: A drum head includes: a first film including a striking surface; a second film disposed opposed to a back surface of the first film which is back from the striking surface; and a sensor disposed between the first film and the second film and configured to output a signal related to vibration. The sensor includes: a first contact surface configured to contact the back surface of the first film without being secured to the back surface; and a second contact surface configured to contact a front surface of the second film without being secured to the front surface. A sensor tail of the sensor is secured to at least one of the first film and the second film located outside the shell when the first film and the second film are stretched over an open end of a shell.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: September 3, 2019
    Assignee: YAMAHA CORPORATION
    Inventor: Ryuji Hashimoto
  • Patent number: 10400016
    Abstract: The present disclosure provides hNGAL muteins that bind CGRP and can be used in various application including pharmaceutical applications, for example, migraine. The present disclosure also concerns methods of making one or more muteins described herein as well as compositions and combinations comprising one or more of such muteins. The present disclosure further relates to nucleic acid molecules encoding such muteins and to methods for generation of such muteins and nucleic acid molecules. In addition, the application discloses therapeutic and/or diagnostic uses of these muteins as well as compositions and combinations comprising one or more of such muteins.
    Type: Grant
    Filed: December 7, 2016
    Date of Patent: September 3, 2019
    Assignee: PIERIS PHARMACEUTICALS GMBH
    Inventors: Gabriele Matschiner, Christine Rothe, Alexander Wiedenmann, Rachida Siham Bel Aiba, Marlon Hinner, Andrea Allersdorfer, Bradley Lunde, Kazufumi Kubota, Mitsuhiro Makino, Sakiko Takahashi, Ryuji Hashimoto, Tohru Takahashi, Mamoru Otoyo
  • Publication number: 20190251934
    Abstract: Provided is a percussion instrument including a substantially cylindrical barrel and a weight fixed to the barrel. More specifically, a plurality of weights 5A to 5D may be provided on the inner circumferential surface of a shell 2 of a drum 1 (a percussion instrument). The weights 5A to 5D may be provided at positions where the weights 5A to 5D have four-fold rotational symmetry in the circumferential direction of the shell 2. The weights 5A to 5D may be each provided between lugs 3 that are provided adjacent to each other on the outer circumferential surface of the shell 2.
    Type: Application
    Filed: April 29, 2019
    Publication date: August 15, 2019
    Inventors: Ryuji HASHIMOTO, Noritaka NAGAI, Banri ABE