Patents by Inventor S

S has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Surgical instruments for anterior goniotomy
    Patent number: 12226344
    Abstract: A surgical instrument (40, 40A) for performing a goniotomy procedure includes a hand grip (44, 44A) having an elongated configuration with proximal and distal ends. The instrument (40, 40A) includes a tip (52, 52A) connected to the distal end (48, 48A) of the hand grip (44, 44A) which has a cutting means for creating a trabecular cleavage plane resulting in a remaining trabecular leaflet directly below Schwalbe's line in an eye to enhance drainage of aqueous humor from the eye. In one form, the cutting means includes a pair of sloping, arcuate cutting surfaces (70, 70A) that join to define an arcuate cutting edge (74, 74A).
    Type: Grant
    Filed: July 23, 2024
    Date of Patent: February 18, 2025
    Assignees: RAICO International LLC, Innovative Glaucoma Consulting LLC, EyeInnovate LLC
    Inventors: Ronald L. Fellman, Davinder S. Grover, Sebastian S. Grover, Ravi Nallakrishnan
  • Pathogen-resistant animals having modified CD163 genes
    Patent number: 12225889
    Abstract: Non-human animals and offspring thereof comprising at least one modified chromosomal sequence in a gene encoding a CD163 protein are provided. Animal cells that contain such modified chromosomal sequences are also provided. The animals and cells have increased resistance to pathogens, including porcine reproductive and respiratory syndrome virus (PRRSV). The animals and offspring have chromosomal modifications of a CD163 gene. The invention further relates to methods of breeding to create pathogen-resistant animals and populations of animals made using such methods.
    Type: Grant
    Filed: November 30, 2023
    Date of Patent: February 18, 2025
    Assignee: The Curators of the University of Missouri
    Inventors: Randall S. Prather, Kevin D. Wells, Kristin M. Whitworth
  • Methods and systems for predicting dissolved oxygen in seawater using a neural network
    Patent number: 12228560
    Abstract: A method for predicting a dissolved oxygen level in treated seawater includes directing raw seawater from a fluid channel into a deaerator, directing an inert gas and an oxygen scavenger solution into the deaerator, thereby removing dissolved oxygen from the raw seawater such that the treated seawater exits the deaerator, receiving information about a plurality of input parameters comprising a raw seawater flow rate, an inert gas flow rate, and an oxygen scavenger flow rate, implementing a neural network trained to predict the dissolved oxygen level of the treated seawater based on the plurality of input parameters and predicting, with the neural network, the dissolved oxygen level of the treated seawater based on the plurality of input parameters.
    Type: Grant
    Filed: October 5, 2021
    Date of Patent: February 18, 2025
    Assignee: Saudi Arabian Oil Company
    Inventors: Prafulchandra Bhavanbhai Sonara, Abdulrahman S. Johar
  • Capacitive coupled return path pad with separable array elements
    Patent number: 12226151
    Abstract: A return pad of an electrosurgical system is disclosed. The return pad includes a plurality of conductive members and a plurality of sensing devices. The conductive members are configured to receive radio frequency current applied to a patient. The sensing devices are configured to detect at least one of the following: a nerve control signal applied to the patient; and a movement of an anatomical feature of the patient resulting from application of the nerve control signal.
    Type: Grant
    Filed: June 8, 2022
    Date of Patent: February 18, 2025
    Assignee: Cilag GmbH International
    Inventors: Frederick E. Shelton, IV, David C. Yates, Cameron R. Nott, Tamara S. Widenhouse, Jason L. Harris
  • Medical device operational modes
    Patent number: 12226645
    Abstract: An ambulatory medical device comprising: a monitoring component comprising at least one sensing electrode for detecting a cardiac condition of a patient; at least one processor configured for: adjusting one or more detection parameters for detecting the cardiac condition of the patient based at least in part on at least one of 1) one or more environmental conditions and 2) input received from the monitoring component; and providing at least one of an alarm and a treatment in response to detecting the cardiac condition of the patient based on the adjusted one or more detection parameters.
    Type: Grant
    Filed: November 8, 2022
    Date of Patent: February 18, 2025
    Assignee: ZOLL Medical Corporation
    Inventors: Gary A. Freeman, Thomas E. Kaib, Shane S. Volpe
  • Electronic pressure regulating valve control for generators
    Patent number: 12231025
    Abstract: A method includes pumping coolant into a cooling system of a generator while the generator is generating electrical power. The method includes regulating flow into the cooling system using a pressure relief valve to recirculate a portion of the coolant back to an inlet of the pump. Using the pressure relief valve includes actuating the pressure relief valve based on input from the cooling system and/or from the generator.
    Type: Grant
    Filed: April 8, 2022
    Date of Patent: February 18, 2025
    Assignee: Hamilton Sundstrand Corporation
    Inventors: Dhaval S. Patel, Glenn C. Lemmers, Jr.
  • Electronic vaping device with outlet-end illumination
    Patent number: 12232223
    Abstract: A cartridge for an e-vaping device includes a housing extending along a longitudinal axis of the cartridge, and an outlet-end insert coupled to the outlet end of the housing. The housing at least partially encloses a pre-vapor formulation reservoir and a vapor generator of the cartridge and further channels light via internal reflection through an interior of the housing. The outlet-end insert includes an outlet in flow communication with the vapor generator, directs the vapor generated by the vapor generator out of the cartridge through the outlet, and further emits the light channeled through the interior of the housing. One or more properties of the light are controllable.
    Type: Grant
    Filed: July 14, 2023
    Date of Patent: February 18, 2025
    Assignee: Altria Client Services LLC
    Inventors: Christopher S. Tucker, Phillip Diana, Nam Tran, Matthew Caparrelli
  • Prosthetic heart valve
    Patent number: 12226312
    Abstract: A prosthetic heart valve can include a radially expandable and compressible frame having an inflow end, an outflow end, and a plurality of struts. The prosthetic valve can further include a valvular structure comprising a plurality of leaflets, each leaflet comprising a coaptation edge portion and a cusp edge portion. The cusp edge portion of each leaflet can be folded toward the outflow end of the frame along a bending axis and a reinforcing member extends along an outflow surface of the cusp edge portion along the bending axis. The prosthetic heart valve can include a plurality of connecting skirts, each disposed between the cusp edge portion of an adjacent leaflet and the frame. First stitching secures the reinforcing member and the connecting skirts to the cusp edge portions and second stitching secures the connecting skirts to selected struts of the frame.
    Type: Grant
    Filed: May 12, 2023
    Date of Patent: February 18, 2025
    Assignee: EDWARDS LIFESCIENCES CORPORATION
    Inventors: Nikolai Gurovich, Michael Bukin, Elena Sherman, Tamir S. Levi, Ziv Yohanan, Gil Senesh, Dikla Kersh, Alexey Tsypenyuk, Waina Michelle Chu, Alexander Barash
  • Method of preparing silanols with selective cytochrome P450 variants and related compounds and compositions
    Patent number: 12227529
    Abstract: This disclosure provides a method of preparing a silanol-functional organosilicon compound with a cytochrome P450 variant that facilitates the oxidization of a silyl hydride group to a silanol group in the presence of oxygen. The method includes combining the cytochrome P450 variant and an organosilicon compound having at least one silicon-bonded hydrogen atom to give a reaction mixture and exposing the reaction mixture to oxygen to oxidize the organosilicon compound, thereby preparing the silanol-functional organosilicon compound. Cytochrome P450 variants suitable for use in the method are also disclosed, along with methods for engineering and optimizing the same. Nucleic acids encoding the cytochrome P450 variants and compositions, expression vectors, and host cells including the same are also disclosed.
    Type: Grant
    Filed: February 19, 2021
    Date of Patent: February 18, 2025
    Assignees: DOW SILICONES CORPORATION, CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: John Roberts, Dimitris Elias Katsoulis, Susanne Baehr, Sabine Brinkmann-Chen, S. B. Jennifer Kan, Frances H. Arnold
  • Centrally controlling communication at a venue
    Patent number: 12229471
    Abstract: One example may include a method that includes initiating an audio recording to capture audio data, comparing the audio data received from a microphone of a mobile device to an audio data range, determining whether the audio data is above an optimal level based on a result of the comparison, and queuing the audio data in an audio data queue when the audio data is above the optimal level.
    Type: Grant
    Filed: August 30, 2022
    Date of Patent: February 18, 2025
    Assignee: Biamp Systems, LLC
    Inventors: Nicholas William Metzar, Richard S. Juszkiewicz, Matthew V. Kotvis, Jason E. Damori
  • Stacked transistors with different channel widths
    Patent number: 12230544
    Abstract: A semiconductor device includes a first stack of nanowires above a substrate with a first gate structure over, around, and between the first stack of nanowires and a second stack of nanowires above the substrate with a second gate structure over, around, and between the second stack of nanowires. The device also includes a first source/drain region contacting a first number of nanowires of the first nanowire stack and a second source/drain region contacting a second number of nanowires of the second nanowire stack such that the first number and second number of contacted nanowires are different.
    Type: Grant
    Filed: November 2, 2022
    Date of Patent: February 18, 2025
    Assignee: Adeia Semiconductor Solutions LLC
    Inventors: Kangguo Cheng, Lawrence A. Clevenger, Balasubramanian S. Pranatharthiharan, John Zhang
  • In-flow photooxygenation of aminothienopyridinones generates novel PTP4A3 phosphatase inhibitors
    Patent number: 12227515
    Abstract: The disclosure provides compounds that inhibit protein tyrosine phosphatase, such as protein tyrosine phosphatase 4 A3 (PTP4A3). The disclosure also provides pharmaceutical compositions, uses, and methods of using the compounds, such as in the treatment of cancers.
    Type: Grant
    Filed: November 12, 2019
    Date of Patent: February 18, 2025
    Assignees: University of Virginia Patent Foundation, University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: John S. Lazo, Elizabeth Sharlow, Peter Wipf, Nikhil Tasker, Ettore Rastelli
  • Lateral gate material arrangements for quantum dot devices
    Patent number: 12230687
    Abstract: Disclosed herein are lateral gate material arrangements for quantum dot devices, as well as related computing devices and methods. For example, in some embodiments, a quantum dot device may include: a quantum well stack; and a gate above the quantum well stack, wherein the gate includes a gate electrode, the gate electrode includes a first material proximate to side faces of the gate and a second material proximate to a center of the gate, and the first material has a different material composition than the second material.
    Type: Grant
    Filed: December 10, 2020
    Date of Patent: February 18, 2025
    Inventors: Roza Kotlyar, Stephanie A. Bojarski, Hubert C. George, Payam Amin, Patrick H. Keys, Ravi Pillarisetty, Roman Caudillo, Florian Luethi, James S. Clarke
  • Methods for assessing risk of developing a viral disease using a genetic test
    Patent number: 12227807
    Abstract: This document provides methods and materials related to treating a disease. For example, this document provides methods for treating a subject's disease based on identifying the risk of progressive multifocal leukoencephalopathy PML using a genetic test.
    Type: Grant
    Filed: April 25, 2024
    Date of Patent: February 18, 2025
    Assignees: PML Screening, LLC, The Université Paris-Saclay, The Assistance Publique—Hôpitaux de Paris (APHP), The Institut National de la Santé et de la Recherche Médicale (INSERM)
    Inventors: Eli Hatchwell, Peggy S. Eis, Edward B. Smith, III, Yassine Taoufik
  • Combustion section with a primary combustion chamber and a secondary combustion chamber
    Patent number: 12228286
    Abstract: A combustion section of a turbine engine having a primary combustion chamber and a secondary combustion chamber. The primary combustion chamber is defined, at least in part, by a combustor liner and a dome wall. A primary fuel nozzle having an outlet is located at the dome wall, wherein the outlet of the primary fuel nozzle is fluidly coupled with the primary combustion chamber. At least one opening located in an outer liner axially aft of the dome wall fluidly couples the secondary combustion chamber and the primary combustion chamber. A set of secondary fuel nozzles are fluidly coupled with the secondary combustion chamber.
    Type: Grant
    Filed: September 29, 2023
    Date of Patent: February 18, 2025
    Assignee: General Electric Company
    Inventors: Pradeep Naik, Hiranya Kumar Nath, Perumallu Vukanti, Clayton S. Cooper, Steven C. Vise, Michael A. Benjamin, R Narasimha Chiranthan
  • Footwear having sensor system
    Patent number: 12225980
    Abstract: A shoe has a sensor system operably connected to a communication port. Performance data is collected by the system and can be transferred for further use via the communication port. The shoe may contain an electronic module configured to gather data from the sensors. The module may also transmit the data to an external device for further processing. Users can use the collected data for a variety of different uses or applications.
    Type: Grant
    Filed: June 29, 2023
    Date of Patent: February 18, 2025
    Assignee: NIKE, Inc.
    Inventors: Matthew A. Nurse, Jeffrey C. Pisciotta, Allan M. Schrock, James C. Meschter, Michael S. Amos, Andrew A. Owings
  • System for social versioning
    Patent number: 12229725
    Abstract: A system for generating of posts, the system including: a server; and a network connection for the server; the server to: maintain a database of users and corresponding user behavior when generating a post on a specific topic; match a first user generating a current post and a topic of the current post to user behavior in the database; based on the matching user behavior from the database, identify different versions during development of the current post; and dictate distribution of different versions of the post based on the matching user behavior from the database.
    Type: Grant
    Filed: June 12, 2018
    Date of Patent: February 18, 2025
    Assignee: International Business Machines Corporation
    Inventors: Paul R. Bastide, Lin Sun, Liam S. Harpur, Matthew E. Broomhall
  • System and method for determining an interest in promotional content displayed at a mobile communication device
    Patent number: 12231489
    Abstract: Determining interest in promotional content to be displayed at a mobile communication device is described. The promotional content, including a first portion that is visible and a second portion that is hidden in a first state, may be received. The first and second portions are each selectable only when visible. A promotional display that includes the promotional content in the first state is generated. Upon receipt of a first input from the user in relation to the first portion, the promotional content may be transitioned from the first state to a second state such the first portion becomes hidden and the second portion becomes visible. Upon failing to receive a second input from the user in relation to the second portion, the promotional content may be transitioned from the second state to the first state. Upon receipt of the second input, an interest in the promotional content may be indicated.
    Type: Grant
    Filed: August 2, 2021
    Date of Patent: February 18, 2025
    Assignee: GOOGLE LLC
    Inventors: James S. Kelm, Thompson Alexander Ivor Gawley, Yelena Nakhimovsky, Jonathan Yu
  • Stud film cooling for double wall combustors
    Patent number: 12228076
    Abstract: A combustor panel is disclosed herein. The combustor panel includes a top side, a bottom side opposite the top side, a feature coupled to the top side and extending orthogonally away from the top side, the feature defining a first space on the bottom side beneath the feature, a first plurality of cooling holes extending in a first direction from the top side to the bottom side, a second plurality of cooling holes extending in a second direction from the top side to the bottom side, the second direction being rotated about 1° to about 60° counter-clockwise from the first direction, and a third plurality of cooling holes extending in a third direction from the top side to the bottom side, the third direction being about rotated 1° to about 60° clockwise from the first direction.
    Type: Grant
    Filed: July 20, 2023
    Date of Patent: February 18, 2025
    Assignee: RTX CORPORATION
    Inventors: Timothy S Snyder, Roger O. Coffey, Lourdes M. Tafur Bermudez, Ryan Kimball Lundgreen, Dibesh D. Joshi
  • Expression systems and methods of use thereof
    Patent number: 12227771
    Abstract: Expression systems for the expression of an ?9?10 nicotinic acetylcholine receptor (nAChR) are described. Also described are methods of using the expression systems to identify agonists, antagonists, or allosteric modulators of an ?9?10 nAChR.
    Type: Grant
    Filed: May 15, 2020
    Date of Patent: February 18, 2025
    Assignee: JANSSEN PHARMACEUTICA NV
    Inventors: David S. Bredt, Weston Davini, Shenyan Gu, Jose Matta, Min Lei O'Carroll