Abstract: An imaging system for low-power and low data-rate applications is provided. The imaging system comprises a pixel array having a plurality of photosensitive elements (pixels) divided into a plurality of groups of photosensitive elements (super pixels). An image processor is operably connected to the pixel array and configured to selectively operate each group of photosensitive elements in either (i) a high resolution mode in which the pixel array outputs readout voltages corresponding to all of the photosensitive elements in the respective group of photosensitive elements or (ii) a low resolution mode in which the pixel array outputs readout voltages corresponding to only a subset of the photosensitive elements in the respective group of photosensitive elements. Groups of photosensitive elements corresponding to detected motion in each image frame are operated in the high resolution mode, while the remaining groups of photosensitive elements are operated in the low resolution mode.

Abstract: Lateral flow immunoassay devices for determining the concentration of an analyte in a sample and methods for measuring analyte concentration in sample using such lateral flow immunoassay devices.

Abstract: A retinal imaging system includes an eyepiece lens assembly, an image sensor, a dynamic fixation target viewable through the eyepiece lens assembly, and a controller coupled to the image sensor and the dynamic fixation target. The controller includes logic that causes the retinal imaging system to perform operations including: acquiring a first image of the eye, analyzing the first image to determine whether a lateral misalignment between the eye and the eyepiece lens assembly is greater than a threshold misalignment, in response to determining the lateral misalignment is greater than the threshold misalignment, adjusting a visual position of the dynamic fixation target to encourage the eye to rotate in a direction that compensates for the lateral misalignment, and acquiring the retinal image of the eye while the eye is encouraged to rotate towards the direction that compensates for the lateral misalignment.

Abstract: A vision traffic marker network system comprises a plurality of vision traffic markers or traffic nodes configured to capture information such as an event, an environment, a profile, or a condition of an object such as vehicle, human, combination thereof, or the like, for example. The environment information may be time of day, day of week, weather, traffic condition, and the like. The nodes may be one of a traffic node, an ambient node, a repeater, a gateway, or a combination thereof. These nodes are arranged in network neighborhoods and configured to communicate with at least one of the communication networks with at least one of the vision traffic markers or nodes, a control system, the automotive, a server, a global navigation system, other non-vision devices, traffic lights, street lights, electronic devices, or combination thereof, via one more links, either wirelessly or wired communication.

Abstract: A retinal imaging system includes an image sensor for acquiring a retinal image and a dynamic illuminator for illuminating a retina to acquire the retinal image. The dynamic illuminator includes a center baffle along with first and second illumination arrays. The center baffle extends from and surrounds an aperture through which an image path for the retinal image passes before reaching the image sensor. The first illumination array extends out from first opposing sides of the aperture along a first linear axis. The second illumination array extends out from second opposing sides of the aperture along a second linear axis that is substantially orthogonal to the first linear axis.

Abstract: A system and method for monitoring outlier behavior in an array of n electrodes includes an electrical line, a switching circuit via which the electrodes are individually coupleable to the electrical line, a sensor; and processing circuitry, where, in each of m iterations: (i) a respective subset of electrodes is coupled by the switching circuit to the electrical line, (ii) the sensor senses an electrical parameter produced over the electrical line by the coupled subset of electrodes, and (iii) the processing circuitry obtains from the sensor a respective value of the electrical parameter, m being less than n, and the processing circuitry identifying those of the electrodes that exhibit outlier electrical behavior by finding electrical values to individually ascribe to individual ones of the electrodes of the array, which ascribed values can result in all of the respective values of all of the m iterations.

Abstract: A system and method of providing a confidence test in one embodiment includes determining a first quality metric based upon a first and a second test environment wherein the second test environment is different from the first test environment, exposing a sample to a plurality of test sites, establishing the first test environment at a first of the plurality of test sites, establishing the second test environment at a second test site, obtaining a first detection signal associated with the first of the plurality of test sites exposed to the sample and at the first test environment, obtaining a second detection signal associated with the second of the plurality of test sites exposed to the sample and at the second test environment, determining a second quality metric based upon the first detection signal and the second detection signal, and comparing the second quality metric with the first quality metric.

Abstract: Apparatuses and methods for an interposer for integration of multiple image sensors are disclosed herein. An example apparatus includes an interposer including laterally spaced first and second windows, and first and second image sensors disposed on the interposer over the first and second windows, respectively. The interposer including conductive conduits formed in or on to provide electrically conductive paths there through with the first and second image sensors coupled to the conductive conduits. The first and second image sensors laterally spaced by a gap, and an active area of the first and second image sensors to receive incident light through the respective first and second windows, where a perspective of the first image is different than a perspective of the second image sensor based at least in part on the gap.

Abstract: Device for use in a biosensor comprising a multisite array of test sites, the device being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest from a biological by modulating the pH or ionic gradient near the electrodes in such biosensor. The device provides a biosensor which is more accurate, reliable and the results of which are more reproducible. Analytic methods for more accurately measuring an analyte of interest in a biological sample are also provided.

Abstract: Device for use in a biosensor comprising a multisite array of test sites, the device being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest from a biological by modulating the pH or ionic gradient near the electrodes in such biosensor. The device provides a biosensor which is more accurate, reliable and the results of which are more reproducible. Analytic methods for more accurately measuring an analyte of interest in a biological sample are also provided.

Abstract: Device and methods for use in a biosensor comprising a multisite array of test sites, the device and methods being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest by modulating the pH or ionic gradient near the electrodes in such biosensor. An electrochemically active agent that is suitable for use in biological buffers for changing the pH of the biological buffers. Method for changing the pH of biological buffers using the electrochemically active agents. The methods of modulating the binding interactions provided in a biosensor, analytic methods for more accurately controlling and measuring the pH or ionic gradient near the electrodes in such biosensor, and analytic methods for more accurately measuring an analyte of interest in a biological sample.

Abstract: A device for generating thermal images includes a low resolution infrared (IR) sensor supported within a housing and having a field of view. The IR sensor is configured to generate thermal images of objects within the field of view having a first resolution. A spatial information sensor supported within the housing is configured to determine a position for each of the thermal images generated by the IR sensor. A processing unit supported within the housing is configured to receive the thermal images and to combine the thermal images based on the determined positions of the thermal images to produce a combined thermal image having a second resolution that is greater than the first resolution.

Abstract: An imaging device for imaging an eye includes an eyepiece, an illumination system, an imaging system, and a controller. The illumination system includes a light source that emits illumination light along an illumination path through the eyepiece to the eye to produce a retinal diffuse reflection and a corneal specular reflection. The imaging system includes a first camera that captures a retinal image based on the retinal diffuse reflection and a first set of optical elements, a second camera that captures a corneal specular reflection image based on the corneal specular reflection and a second set of optical elements. The first camera captures at least some residual corneal specular reflection in the retinal image. The controller subtracts the residual corneal specular reflection from the retinal image based on the corneal specular reflection image.

Abstract: Device and methods for use in a biosensor comprising a multisite array of test sites, the device and methods being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest by modulating the pH or ionic gradient near the electrodes in such biosensor. An electrochemically active agent that is suitable for use in biological buffers for changing the pH of the biological buffers. Method for changing the pH of biological buffers using the electrochemically active agents. The methods of modulating the binding interactions provided in a biosensor, analytic methods for more accurately controlling and measuring the pH or ionic gradient near the electrodes in such biosensor, and analytic methods for more accurately measuring an analyte of interest in a biological sample.

Abstract: A coated electrode includes an electrode, a coating configured to immobilize biomolecules, and a coating configured to improve electron transfer rate. Methods of making the coated electrode are also provided. A biosensor comprises a plurality of electrodes, each electrode including the coated electrode.

Abstract: The technology described herein is directed to a fundus camera and, more specifically, to a fundus camera having a display that projects active visual alignment stimuli onto an eye of an examinee via one or more components of an optimal assembly. The active visual alignment stimuli are dynamically adjusted to guide an examinee toward optical alignment for fundus imaging.

Abstract: An apparatus for imaging an interior of an eye includes a light sensitive sensor, a plurality of light emitters (LEs) capable of outputting light, a plurality of nonvisible light emitters (NV-LEs) capable of outputting nonvisible light, and a controller. The controller is coupled to the plurality of LEs, the plurality of NV-LEs, and the light sensitive sensor, and the controller implements logic that when executed by the controller causes the apparatus to perform operations. The operations include illuminating the eye with the nonvisible light from the plurality of NV-LEs, and determining an amount of reflection of the nonvisible light from the eye for each of the NV-LEs in the plurality of NV-LEs. The operations also include illuminating the eye with selected one or more of the LEs in the plurality of LEs, and capturing, with the light sensitive sensor, a sequence of images of the interior of the eye while the eye is illuminated with the light from the LEs.

Abstract: A method of imaging an interior of an eye includes illuminating the interior of the eye with one or more beams of light from a light source, and said illuminating is configured to trigger a change to a pupil of the eye. An image sensor captures a sequence of images of light reflected by the interior of the eye during an expected timeframe when a width of the pupil is changing in response to said illuminating. A processing apparatus combines images in the sequence of images to form a composite image having a larger depth of field than a depth of field of each of the images in the sequence of images. The depth of field for each of the images corresponds to the width of the pupil when each of the images is captured.

Abstract: A technique for retinal images includes configuring a dynamic illuminator to illuminate the retina with an illumination pattern. An image frame of the retina is captured while illuminated with the illumination pattern. The configuring and the capturing are iterated to sequentially reconfigure the dynamic illuminator to illuminate the retina with a plurality of different illumination patterns and to capture a plurality of image frames each illuminated with one of the different illumination patterns. The image frames are combined into a composite retinal image.

Abstract: Lateral flow immunoassay devices for determining the concentration of an analyte in a sample and methods for measuring analyte concentration in sample using such lateral flow immunoassay devices.