Abstract: A messaging server with a future message storage space for future messages, each being a sender created message not yet delivered to a recipient that has an associated sender specified message delivery time. Recipient specific delivery block details are specified for a set of delivery blocks for future messages. The future messages are received processed and stored. Until the respective sender specified message delivery time a respective one of the set of senders is able to retract and edit a corresponding one of the future messages. Future messages are delivered at the delivery time consistent with the delivery blocks. After delivery the sender is unable to retract and edit a corresponding delivered message. Future messages do not alert a recipient of arrival until the sender established delivery time, which minimizes cognitive distractions and provides the sender with notice for anticipating a time of response, without overly distracting the recipient.

Abstract: A system and method to record and trace data exchanges between cooperating hardware unit operations and software unit operations, providing an efficient mechanism to trace back to a root cause point from an observed failure point in a series of executed instructions performed within a data processing system. A data debug memory records information pertaining to each system memory access performed by instructions executed by the hardware and software units into separate memory information blocks. Linked relationships are created between certain ones of the memory information blocks to represent data dependencies that occurred between the instructions. These linked relationships may then be utilized to generate lists that map the various data dependencies between the executed instructions.

Abstract: Systems and method for idle loop detection and control are disclosed. A processor operates in operating modes including an active mode and a disabled mode, and an interconnect bus is coupled between the processor and one or more additional electronic circuits. Logic within the processor is coupled to snoop the interconnect bus, and the logic is programmed to detect a new idle loop based upon repeated instructions on the interconnect bus and to place the processor in the disabled mode based upon execution of the new idle loop, which represents a previously unknown idle loop for the processor. Further, the logic can be programmed to store state data for the processor when the new idle loop is detected, and the logic can also be programmed to place the processor in the active mode based upon detection of a wakeup event for the new idle loop on the interconnect bus.

Abstract: Provided herein is a composition and a method for treating nucleic acid-related eye disease.

Abstract: A containerized architecture to secure and manage Internet-connected devices, such as “Internet of Things” devices, is disclosed. In various embodiments, one or more containerized applications are run, e.g., on an Internet of Things gateway, subject to management by the management server. At least one of the containerized applications is a management agent configured to participate, subject to control of the management server, in management of one or more other of said containerized applications.

Abstract: Provided herein is a composition and a method for treating nucleic acid-related eye disease.

Abstract: Various embodiments relate to a circuit, including: a first secure circuit configured to receive an input and to produce a first output; a first delay circuit configured to receive the first output and to produce a first delayed output delayed by a time N; a second delay circuit configured to receive the input and to produce a delayed input delayed by a time N; a second secure circuit configured to receive the delayed input and to produce a second delayed output; and a comparator configured to compare the first delayed output to the second delayed output and to produce a result, wherein the result is one of the first delayed output or second delayed output when the first delayed output matches the second delayed output and the result is an error value when the first delayed output does not match the second delayed output.

Abstract: The various embodiments herein disclose a system and method for generating a delta code coverage information. The system for generating delta code coverage information comprises, a source control module configured for storing a plurality of software program code files to be processed and a plurality of code coverage data corresponding to the plurality of software program code files, a processor configured to generate a delta code coverage data for analysis for each of the plurality of software program code files on a line level or at a branch level by performing a time based delta code coverage process and a path based delta code coverage process.

Abstract: The invention is directed to a process for recovering/purifying (meth)acrylic acid which does not use azeotropic solvent and is based on the use of two columns for purifying a reaction mixture comprising (meth)acrylic acid. The process according to the invention includes a dry vacuum pump condensation system, which makes it possible to reduce the amount of final aqueous discharges.

Abstract: A process for the recovery of polymer-grade (meth)acrylic acid, in the absence of organic solvent, from a gaseous reaction mixture comprising (meth)acrylic acid obtained by gas-phase oxidation of a precursor of the (meth)acrylic acid, the process carried out in a plant comprising at least one dehydration column and one finishing column, being characterized by the presence of at least one chemical treatment agent targeted at reducing the content of residual aldehydes. (Meth)acrylic acid obtained according to the invention meets criteria of high quality allowing it to be used in the manufacture of acrylic polymers, in particular for superabsorbents. This grade is also known as glacial acrylic acid GAA.

Abstract: A medical protective gown comprising a gown body. A centrally located orifice passes through a central region of a front panel of the gown body. A tubular protective sleeve extends forward from the front panel of the gown body, the tubular protective sleeve being located circumscribing the centrally located orifice. A tubular protective sleeve distal end panel is located at a distal end of the tubular protective sleeve. The tubular sleeve is adapted to receive a stethoscope or any other desired medical instrument. A broadened interior pocket is assembled to an interior surface of the gown body to support an upper, broader portion of the stethoscope or other instrument. A flange can be included with the tubular protective sleeve and/or the broadened interior pocket to aid in attachment to the gown body. The tubular protective sleeve can include a sleeve contraction system to contract the protective sleeve.

Abstract: The present invention relates to an improved process for the preparation of Valacyclovir or pharmaceutically acceptable salts thereof, which comprises reaction of amine-protected Valacyclovir or its salt with deprotecting agent in a continuous flow reactor.

Abstract: An aspect of the present disclosure provides run-time adaption of external properties controlling operation of applications. In one embodiment, a setup data is maintained indicating conditions and properties that control the operation of applications. Each property is associated with a corresponding condition in the setup data to indicate that the property is to be configured upon satisfaction of the corresponding condition. In response to determining that a specific condition indicated in the setup data has been satisfied, a set of properties that is associated with the determined condition is identified. The applications are then automatically configured to thereafter operate with the identified set of properties.

Abstract: The present invention provides an ophthalmic formulation consisting essentially of one or more pharmaceutically acceptable excipients; a pharmaceutically active compound that is capable of reducing the amount of inflammatory neutrophil product on the ocular surface; and optionally a second pharmaceutically active compound selected from the group consisting of a steroid, an anti-inflammatory agent, a mucolytic agent and a combination thereof. In particular, the present invention provides an ophthalmic formulation where the pharmaceutically active compound is capable of treating a clinical condition selected from the group consisting of inflammatory and immunological ocular surface disease that can cause symptoms of ocular discomfort, mucocellular aggregates/debris in tear film, symblepheron formation, fornix foreshortening, eyelid margin/conjunctival keratinization, corneal neovascularization/pannus, subconjunctival fibrosis, and herpetic eye disease.

Abstract: The present invention provides a composition comprising two or more of the following pharmaceutically active compounds: (i) an alpha 2 adrenergic agonist; (ii) a corticosteroid; (iii) a lymphocyte function-associated antigen antagonist; (iv) a non-steroidal anti-inflammatory drug (NSAID); (v) a sodium channel blocker; and (vi) an antibiotic, provided at least one of the pharmaceutically active compound is selected from the group consisting of (i) alpha 2 adrenergic agonist and (ii) corticosteroid.

Abstract: A system and method to record and trace data exchanges between cooperating hardware unit operations and software unit operations, providing an efficient mechanism to trace back to a root cause point from an observed failure point in a series of executed instructions performed within a data processing system. A data debug memory records information pertaining to each system memory access performed by instructions executed by the hardware and software units into separate memory information blocks. Linked relationships are created between certain ones of the memory information blocks to represent data dependencies that occurred between the instructions. These linked relationships may then be utilized to generate lists that map the various data dependencies between the executed instructions.

Abstract: In accordance with an embodiment, described herein is a system and method for optimizing cloud infrastructure through client request classification in a cloud computing environment. The cloud infrastructure can include one or more high-compute infrastructure instances, and one or more standard-compute infrastructure instances. Each request received at a load balancer can be checked against a request classification cache, to determine whether the request has been classified, and if it has been classified, whether the request can be routed to a high-compute infrastructure instance or a standard-compute infrastructure instance based on a classification of the request. An unclassified request can be classified based on a plurality of request parameters, and threshold values derived from the cloud infrastructure; and can be stored in the request classification cache. Classified requests in the classification cache can be provided to a cloud vendor for use in optimizing the cloud infrastructure.

Abstract: A cooling system having a cooling chamber including a surface defining one or more openings. A surface is configured to hold at least one container. An access door provides access to the cooling chamber. A refrigeration system is configured to cool the cooling chamber by forcing cool airflow through the one or more openings in the surface. The airflow through each of the one or more openings may be similar.

Abstract: The present invention relates to the manufacture of biobased acrylic acid from glycerol as starting material, the term “biobased acid” indicating that the acrylic acid is essentially based on a carbon source of natural origin.

Abstract: The present invention provides a preservative free ophthalmic formulation. In particular, the ophthalmic formulations of the invention are aqueous formulations comprising nanoemulsion of oil. The present invention also provides a method for treating an eye disorder. In one particular embodiment, the invention provides methods for treating dry eye syndrome using an preservative free formulation comprising a nanoemulsion of oil and alpha 2 adrenergic agonist, pharmaceutically acceptable salt thereof or a mixture thereof. In particular, the alpha 2 adrenergic agonist of the invention has a higher alpha 2A agonist activity compared to alpha 2B agonist activity. This invention also provides a preservative free ophthalmic composition comprising a nanoemulsion of oil, a therapeutically effective amount of an alpha 2 adrenergic agonist, a pharmaceutically acceptable salt thereof or a combination thereof as an active ingredient for treating a dry eye syndrome.