Abstract: The invention provides for optimized binuclease fusion proteins with increased pharmacokinetic properties. The optimized binuclease fusion proteins of the invention two or more nuclease domains (e.g., RNase and DNase domain) operably coupled to an Fc domain. The invention also provides methods of treating or preventing a condition associated with an abnormal immune response.

Abstract: A method of character recognition for a personal computing device comprising a user interface capable of receiving inputs that are to be recognized through data input means which are receptive to keyed, tapped or a stylus input, said device being adapted to facilitate a reduction in the number of physical keying actions, tapping actions or gestures required to create a data string to less than the number of characters within said data string: storing a set of data strings each with a priority indicator associated therewith, wherein the indicator is a measure of a plurality of derivatives associated with the data string; recognizing an event; looking up the most likely subsequent data string to follow the event from the set of data strings based on one or more of the plurality of derivatives; ordering the data strings for display based on the priority indicator of that data string.

Abstract: Embodiments disclose systems and methods for transmitting user-extracted video and content more efficiently by recognizing that user-extracted video provides the potential to treat parts of a single frame of a user-extracted video differently. An alpha mask of the image part of the user-extracted video is used when encoding the image part so that it retains a higher quality upon transmission than the remainder of the user-extracted video.

Abstract: This document presents a system and method for preference pre-configuration of automatic association coordinator modules used to control lights, audio systems, and any other home automation device. The preferences define and control moods and experiences associated with one or more spaces within a residential or commercial property. Moods and experiences may be defined by the user to present specified settings for audio, lighting, security, or other parameters that contribute to a mood for a given space. Timing and triggers may be created and saved with the moods and experiences to permit automatic, delayed, and cascading ambiance settings for one or more spaces.

Abstract: A processor is configured to implement an instruction set architecture for accessing data that includes loading data elements from a memory containing data blocks separated by block boundaries. The instruction set architecture includes a first type of data load instruction for loading an aligned data structure from the memory and a second type of data load instruction for loading an unaligned data structure from the memory. The loading includes fetching a data load instruction of the second type and loading from the memory according to the data load instruction of the second type. The resulting data structure formed of n consecutive data elements is determined from the data load instruction. The data structure loaded from memory is formed of n consecutive unaligned data elements. The processor is similarly configured to implement storing data elements from a set of registers to a memory containing data blocks separated by block boundaries.

Abstract: Instruction set architectures (ISAs) and apparatus and methods related thereto comprise an instruction set that includes one or more instructions which identify the global pointer (GP) register as an operand (e.g., base register or source register) of the instruction. Identification can be implicit. By implicitly identifying the GP register as an operand of the instruction, one or more bits of the instruction that were dedicated to explicitly identifying the operand (e.g., base register or source register) can be used to extend the size of one or more other operands, such as the offset or immediate, to provide longer offsets or immediates.

Abstract: Embodiments disclosed pertain to apparatuses, systems, and methods for Translation Lookaside Buffers (TLBs) that support visualization and multi-threading. Disclosed embodiments pertain to a TLB that includes a content addressable memory (CAM) with variable page size entries and a set associative memory with fixed page size entries. The CAM may include: a first set of logically contiguous entry locations, wherein the first set comprises a plurality of subsets, and each subset comprises logically contiguous entry locations for exclusive use of a corresponding virtual processing element (VPE); and a second set of logically contiguous entry locations, distinct from the first set, where the entry locations in the second set may be shared among available VPEs. The set associative memory may comprise a third set of logically contiguous entry locations shared among the available VPEs distinct from the first and second set of entry locations.

Abstract: A method includes assigning unique guest identifications to different guests, specifying an address region and permissions for the different guests and controlling a guest jump from one physical memory segment to a second physical memory segment through operational permissions defined in a root memory management unit that supports guest isolation and protection.

Abstract: Embodiments of the invention provide compositions comprising bio degradable polymers, medical implants fabricated from these compositions and methods of using such implants. Many embodiments provide medical implants comprising a first polymer backbone having a first rate of biodegradation and a second polymer backbone having a second rate of biodegradation faster than the first rate. In some embodiments, the second backbone is configured to be replaced by a natural tissue layer. The first backbone provides a scaffold for the implant while the second backbone degrades. This scaffold can enhance mechanical properties of the implant including various aspects of mechanical strength such as tensile, bending, hoop and yield strength; and elasticity. The scaffold also serves to maintain a minimum level of structural support of the implant during the period of degradation of the second backbone or for the entire life of the implant so that the implant does not mechanically fail.

Abstract: Embodiments of the invention provide compositions include bio degradable polymers, medical implants fabricated from these compositions and methods of using such implants. Many embodiments provide medical implants including a first polymer backbone having a first rate of biodegradation and a second polymer backbone having a second rate of biodegradation faster than the first rate. In some embodiments, the second backbone is configured to be replaced by a natural tissue layer. The first backbone provides a scaffold for the implant while the second backbone degrades. This scaffold can enhance mechanical properties of the implant including various aspects of mechanical strength such as tensile, bending, hoop and yield strength; and elasticity. The scaffold also serves to maintain a minimum level of structural support of the implant during the period of degradation of the second backbone or for the entire life of the implant so that the implant does not mechanically fail.

Abstract: Disclosed herein are systems and methods for iterative adjustment of video-capture settings based on identified persona. In an embodiment, a method includes receiving video frames that are being captured by a video camera of an ongoing scene. The method also includes identifying a persona in one or more of the received frames at least in part by identifying, in each such frame, a set of pixels classified as being representative of the persona. The method also includes selecting, based collectively on the brightness values of the pixels in the identified set, a respective adjustment command for one or more adjustable video-capture settings of the camera, as well as outputting the selected commands to the camera for use in continuing to capture video data representative of the ongoing scene.

Abstract: Embodiments disclosed pertain to apparatuses, systems, and methods for Translation Lookaside Buffers (TLBs) that support visualization and multi-threading. Disclosed embodiments pertain to a TLB that includes a content addressable memory (CAM) with variable page size entries and a set associative memory with fixed page size entries. The CAM may include: a first set of logically contiguous entry locations, wherein the first set comprises a plurality of subsets, and each subset comprises logically contiguous entry locations for exclusive use of a corresponding virtual processing element (VPE); and a second set of logically contiguous entry locations, distinct from the first set, where the entry locations in the second set may be shared among available VPEs. The set associative memory may comprise a third set of logically contiguous entry locations shared among the available VPEs distinct from the first and second set of entry locations.

Abstract: Various embodiments provide methods and systems for the biphasic iontophoretic transdermal delivery of therapeutic agents. An embodiment of a method for such delivery comprises positioning at least one electrode assembly in electrical communication with a patient's skin. The assembly includes a solution comprising a therapeutic agent which passively diffuses into the skin. A dose of agent is delivered from the assembly into the skin during a first period using a first current having a characteristic e.g., polarity and magnitude, to repel the agent out of the assembly. During a second period, a second current having a characteristic to attract the agent is used to retain the agent in the assembly such that delivery of agent into skin is minimized. A dose of agent may be delivered on demand by an input from the patient. Embodiments may be used for delivery of agents which cause adverse effects from unwanted passive diffusion.

Abstract: Disclosed herein are methods and systems for combining foreground video and background video using chromatic matching. In an embodiment, a system obtains foreground video data. The system obtains background video data. The system determines a color-distribution dimensionality of the background video data to be either high-dimensional chromatic or low-dimensional chromatic. The system selects a chromatic-adjustment technique from a set of chromatic-adjustment techniques based on the determined color-distribution dimensionality of the background video data. The system adjusts the foreground video data using the selected chromatic-adjustment technique. The system generates combined video data at least in part by combining the background video data with the adjusted foreground video data. The system outputs the combined video for display.

Abstract: Disclosed herein are methods and systems for combining foreground video and background video using chromatic matching. In an embodiment, a system obtains foreground video data. The system obtains background video data. The system determines a color-distribution dimensionality of the background video data to be either high-dimensional chromatic or low-dimensional chromatic. The system selects a chromatic-adjustment technique from a set of chromatic-adjustment techniques based on the determined color-distribution dimensionality of the background video data. The system adjusts the foreground video data using the selected chromatic-adjustment technique. The system generates combined video data at least in part by combining the background video data with the adjusted foreground video data. The system outputs the combined video for display.

Abstract: Adaptive voltage modulation circuits for adjusting supply voltage to reduce supply voltage droops and minimize power consumption are provided. In one aspect, an adaptive voltage modulation circuit detects a supply voltage droop by detecting when a supply voltage falls below a droop threshold voltage, and adjusts a clock signal provided to a load circuit in response to a supply voltage droop. The adaptive voltage modulation circuit keeps a count of the number of clock signal cycles during which the supply voltage is below the droop threshold voltage. The adaptive voltage modulation circuit increases the supply voltage in response to the count exceeding an upper threshold value, and decreases the supply voltage in response to the count being less than a lower threshold value at an end of a defined period. The adaptive voltage modulation circuit can reduce the time a load circuit operates with reduced frequency while minimizing power consumption.

Abstract: Embodiments disclosed pertain to apparatuses, systems, and methods for Translation Lookaside Buffers (TLBs) that support virtualization and multi-threading. Disclosed embodiments pertain to a TLB that includes a content addressable memory (CAM) with variable page size entries and a set associative memory with fixed page size entries. The CAM may include: a first set of logically contiguous entry locations, wherein the first set comprises a plurality of subsets, and each subset comprises logically contiguous entry locations for exclusive use of a corresponding virtual processing element (VPE); and a second set of logically contiguous entry locations, distinct from the first set, where the entry locations in the second set may be shared among available VPEs. The set associative memory may comprise a third set of logically contiguous entry locations shared among the available VPEs distinct from the first and second set of entry locations.

Abstract: This invention relates to a carrier for immobilizing a biocatalyst including a Fe2O3 yolk-shell structure, to an immobilized enzyme using the carrier, and to realizing an increase in the stability of the enzyme and stability in organic solvents by cross-linking the enzyme. According to this invention, the carrier for immobilizing a biocatalyst and the enzyme immobilized thereon can be reused, have increased stability, facilitate the control of reactivity, pH, and temperature, and can be widely useful in various biochemical engineering industries.

Abstract: A method of character recognition for a mobile telephone having a plurality of data input keys. The method facilitates a reduction in the number of user interactions required to create a given data string to less than the number of characters within the data string. The method includes: storing a set of data strings each with a priority indicator; recognizing an event; looking up the most likely subsequent data string to follow the event from the set of data strings; and ordering the data strings for display based on the priority indicator of that data string. If included in the list, the required subsequent data string is selected. If not included in the list, an event is entered and the steps of recognizing the event, looking up and ordering data strings are repeated. The priority indicator of the selected data string and the set of data strings are updated.

Abstract: A system and method process atomic instructions. A processor system includes a load store unit (LSU), first and second registers, a memory interface, and a main memory. In response to a load link (LL) instruction, the LSU loads first data from memory into the first register and sets an LL bit (LLBIT) to indicate a sequence of atomic instructions is being executed. The LSU further loads second data from memory into the second register in response to a load (LD) instruction. The LSU places a value of the second register into the memory interface in response to a store conditional coupled (SCX) instruction. When the LLBIT is set and in response to a store (SC) instruction, the LSU places a value of the second register into the memory interface and commits the first and second register values in the memory interface into the main memory when the LLBIT is set.