Abstract: Provided are a laminate including a first resin layer, an inorganic layer, and a second resin layer, in which a mixed layer is provided between the first resin layer and the inorganic layer and between the second resin layer and the inorganic layer; and a manufacturing method of a laminate.

Abstract: An object is to provide an exposure method and an exposure device for obtaining a photo-alignment film where the accuracy of an alignment pattern is high, and a method of forming an optically-anisotropic layer. In a case where linearly polarized light is focused in a ring shape with an optical member and a film including a compound having a photo-aligned group is exposed, while rotating a polarization direction of the polarized light, the film and the optical member are relatively moved in a direction tilted with respect to an optical axis of the optical member.

Abstract: A method for treating a bone and soft tissue tumor, including administering a conditionally replicating adenovirus having a E1A gene under expression control of a Survivin promoter, to a subject in need thereof. A conditionally replicating adenovirus including a E1A gene under expression control of a Survivin promoter and the conditionally replicating adenovirus is not defective in a E3 region.

Abstract: Provided is an exposure method and an exposure device for obtaining a photo-alignment film where the accuracy of an alignment pattern is high, and a method of manufacturing an optically-anisotropic layer. Provided is an exposure method in which linearly polarized light is focused in a ring shape with an optical member to expose a film including a compound having a photo-aligned group, the method including: an exposure step of relatively moving the film and the optical member in an optical axis direction of the optical member while rotating a polarization direction of the linearly polarized light.

Abstract: Score lines are formed on package material. A spout attachment hole is formed in a portion corresponding to a top gusset section of a pouch. A spout is attached to the spout attachment hole. A portion corresponding to a peripheral edge of the top gusset section of the pouch and a portion corresponding to a top edge of a body section of the pouch are heat-sealed, and the package material is cut in the width direction. Portions corresponding to side edges of the body section of the pouch are heat-sealed, and a portion corresponding to a peripheral edge of a bottom gusset section and a portion corresponding to a peripheral edge of a bottom end portion of the body section are heat-sealed. The heat-sealed portions formed at the portions corresponding to the side edges of the body section of the pouch are cut so a spouted pouch package is released.

Abstract: Provided is a guidewire including a core shaft, an outer flexible tube, a stranded wire that extends parallel to the core shaft, and a hollow stranded-wire coil disposed in the outer flexible tube. The hollow stranded-wire coil is formed of multiple strands and surrounds the distal end portion of the core shaft and the stranded wire. Distal ends of the hollow stranded-wire coil, the core shaft, and the stranded wire are joined to a distal end of the outer flexible tube.

Abstract: Provided is a guidewire including a core shaft, an outer flexible tube, a stranded wire that extends parallel to the core shaft, and a hollow stranded-wire coil disposed in the outer flexible tube. The hollow stranded-wire coil is formed of multiple strands and surrounds the distal end portion of the core shaft and the stranded wire. Distal ends of the hollow stranded-wire coil, the core shaft, and the stranded wire are joined to a distal end of the outer flexible tube.

Abstract: Provided is a guidewire including a core shaft, an outer flexible tube, a stranded wire that extends parallel to the core shaft, and a hollow stranded-wire coil disposed in the outer flexible tube. The hollow stranded-wire coil is formed of multiple strands and surrounds the distal end portion of the core shaft and the stranded wire. Distal ends of the hollow stranded-wire coil, the core shaft, and the stranded wire are joined to a distal end of the outer flexible tube.

Abstract: Provided is a guidewire including a core shaft, an outer flexible tube, and an inner flexible tube that surrounds a distal end portion of the core shaft. The inner flexible tube is disposed in the outer flexible tube so that a distal end thereof is positioned between the distal end of the core shaft and a proximal end of the core shaft so as to be separated from the core shaft. A first joint is formed so as to join the distal end of the inner flexible tube to the core shaft. At least one second joint is formed so as to join the outer flexible tube to the inner flexible tube. The at least one second joint is positioned between the first joint and the proximal end of the core shaft.

Abstract: Provided is a guidewire including a core shaft, an outer flexible tube, a stranded wire that is disposed parallel to a distal end portion of the core shaft, and an inner flexible tube that surrounds a distal end portion of the core shaft and the stranded wire. The inner flexible tube is disposed in the outer flexible tube so that a distal end thereof is positioned between the distal ends of the core shaft and the stranded wire and a proximal end of the core shaft so as to be separated from the distal ends of the core shaft and the stranded wire. A joint is formed so as to join the distal end of the inner flexible tube, the core shaft, and the stranded wire to each other.

Abstract: It is intended to provide a drug to be used in gene therapy which specifically targets abnormal cells such as tumor cells and destroys the same for healing. Namely, a drug comprising, as the active ingredient, a proliferative vector which contains a Survivin promoter proliferating depending on the expression of Survivin. The drug may be used in order to treat tumor. In this drug, use may be made of an adenovirus as the vector. In the adenovirus of this drug, an endogenous promoter of an E1A domain may be substituted with a Survivin promoter.

Abstract: A guidewire includes a core shaft and a coil body wound around an outer periphery of the core shaft. A distal end portion of the core shaft and a distal end portion of the coil body is fixed to each other to form a most distal end portion. The coil body includes a linear portion and a bent portion, the linear portion extending in a distal direction from a proximal end of the coil body, the bent portion being provided on a distal side of the liner portion. The core shaft and the coil body located in the bent portion are fixed to each other with a fixing member.

Abstract: A guidewire includes a core shaft having front and rear sections including a front end portion and a rear section, respectively, an outer coil body that covers the front section, and an inner coil body that is disposed within the outer coil body between the outer coil body and the core shaft, and covers the front section. The outer coil body includes a cylindrical large-diameter section positioned adjacent the rear end portion, a cylindrical small-diameter section positioned adjacent the front end portion, and a tapered section that connects the cylindrical large-diameter section to the cylindrical small-diameter section with a connecting portion provided therebetween, the tapered section having a diameter that decreases from an end adjacent the rear end portion to an end adjacent the front end portion. The inner coil body is disposed at least in the tapered section.

Abstract: A content control system capable of controlling delivery destinations of user contents in respective groups, identifying each group through which each content is delivered, and delivering information/advertisements according to the attribution information of the content. In a content control server, group identifying information is set in each user content to be uploaded to or downloaded from a group memory area corresponding to a gateway ID from a terminal through a gateway having a plurality of its subordinate terminals. The information identifies each gateway through which each object content is delivered according to the gateway ID. The control system controls the delivery destination of each content according to the combination of the content delivery route and a table prepared in the content control server.

Abstract: It is intended to provide a drug to be used in gene therapy which specifically targets abnormal cells such as tumor cells and destroys the same for healing. Namely, a drug comprising, as the active ingredient, a proliferative vector which contains a Survivin promoter proliferating depending on the expression of Survivin. The drug may be used in order to treat tumor. In this drug, use may be made of an adenovirus as the vector. In the adenovirus of this drug, an endogenous promoter of an E1A domain may be substituted with a Survivin promoter.

Abstract: Provided is a guidewire including a core shaft, an outer flexible tube, and an inner flexible tube that surrounds a distal end portion of the core shaft. The inner flexible tube is disposed in the outer flexible tube so that a distal end thereof is positioned between the distal end of the core shaft and a proximal end of the core shaft so as to be separated from the core shaft. A first joint is formed so as to join the distal end of the inner flexible tube to the core shaft. At least one second joint is formed so as to join the outer flexible tube to the inner flexible tube. The at least one second joint is positioned between the first joint and the proximal end of the core shaft.

Abstract: A content recommendation apparatus that can recommend contents suitable to user's taste immediately even after introduction of the system even if a TV set is used by unspecified users. Among previously-determined recommendation ranks of contents, the content recommendation apparatus of the present invention lowers the recommendation rank of a VOD content that is similar to TV programs broadcast in other media at a prescribed time. As the prescribed time, can be employed a time designated by a user, a time on a prescribed cycle, or a time when a TV program on the air in another media is changed, for example.

Abstract: Provided is a guidewire including a core shaft, an outer flexible tube, a stranded wire that extends parallel to the core shaft, and a hollow stranded-wire coil disposed in the outer flexible tube. The hollow stranded-wire coil is formed of multiple strands and surrounds the distal end portion of the core shaft and the stranded wire. Distal ends of the hollow stranded-wire coil, the core shaft, and the stranded wire are joined to a distal end of the outer flexible tube.

Abstract: Provided is a guidewire including a core shaft, an outer flexible tube, and an inner flexible tube that surrounds a distal end portion of the core shaft. The inner flexible tube is disposed in the outer flexible tube so that a distal end thereof is positioned between the distal end of the core shaft and a proximal end of the core shaft so as to be separated from the core shaft. A first joint is formed so as to join the distal end of the inner flexible tube to the core shaft. At least one second joint is formed so as to join the outer flexible tube to the inner flexible tube. The at least one second joint is positioned between the first joint and the proximal end of the core shaft.

Abstract: Provided is a guidewire including a core shaft, an outer flexible tube, and an inner flexible tube that surrounds a distal end portion of the core shaft. The inner flexible tube is disposed in the outer flexible tube so that a distal end thereof is positioned between the distal end of the core shaft and a proximal end of the core shaft so as to be separated from the core shaft. A first joint is formed so as to join the distal end of the inner flexible tube to the core shaft. At least one second joint is formed so as to join the outer flexible tube to the inner flexible tube. The at least one second joint is positioned between the first joint and the proximal end of the core shaft.