Abstract: Provided is a method of preparing a proliferation-regulated recombinant adenoviral vector effectively, comprising preparing a proliferation-regulated vector plasmid by preparing a restriction enzyme-recognizing sequence in a vector plasmid having a proliferation-regulating unit and having an E1A region, a protein-coding region in a E1B region, a poly(A) signal sequence, and a recombinase-recognizing sequence in that order from upstream, by deleting an endogenous promoter in the E1A region or an endogenous promoter regulating expression of the protein-coding gene in one protein-coding region of the E1B region thereof and inserting the restriction enzyme-recognizing sequences in the deficient site, and introducing a promoter expressing specifically in a target organ in the restriction enzyme-recognizing sequence in the restriction enzyme-recognizing sequence; and additionally, integrating the proliferation-regulated vector plasmid into a vector plasmid having a adenoviral genome prepared by deleting the E1 regi

Abstract: A method of coating a moving web of a substrate with a coating, includes applying the coating to the substrate to provide a coating thickness distribution curve along a width direction of the substrate such that: the coating thickness decreases from a position where the thickness is the maximum to the opposite ends of the curve and that the distribution curve has the least curvature at the position with the maximum thickness and contains an end portion having a larger curvature than that of the position with the maximum thickness on both sides of the position with the maximum thickness.

Abstract: A viewing control apparatus for viewing a broadcast program, includes a processor which controls channel switching of the broadcast program and reproduction of VOD (Video on Demand) contents. The processor generates a virtual channel in combination of the broadcast program and automatically-recommended VOD contents, controls channel switching of the broadcast program and reproduction of the VOD contents based on a program list of the generated virtual channel, and switches an image displayed on a display unit.

Abstract: Provided is a guidewire including a core shaft, an outer flexible tube, a stranded wire that extends parallel to the core shaft, and a hollow stranded-wire coil disposed in the outer flexible tube. The hollow stranded-wire coil is formed of multiple strands and surrounds the distal end portion of the core shaft and the stranded wire. Distal ends of the hollow stranded-wire coil, the core shaft, and the stranded wire are joined to a distal end of the outer flexible tube.

Abstract: Provided is a guidewire including a core shaft, an outer flexible tube, and an inner flexible tube that surrounds a distal end portion of the core shaft. The inner flexible tube is disposed in the outer flexible tube so that a distal end thereof is positioned between the distal end of the core shaft and a proximal end of the core shaft so as to be separated from the core shaft. A first joint is formed so as to join the distal end of the inner flexible tube to the core shaft. At least one second joint is formed so as to join the outer flexible tube to the inner flexible tube. The at least one second joint is positioned between the first joint and the proximal end of the core shaft.

Abstract: Provided is a guidewire including a core shaft, an outer flexible tube, a stranded wire that is disposed parallel to a distal end portion of the core shaft, and an inner flexible tube that surrounds a distal end portion of the core shaft and the stranded wire. The inner flexible tube is disposed in the outer flexible tube so that a distal end thereof is positioned between the distal ends of the core shaft and the stranded wire and a proximal end of the core shaft so as to be separated from the distal ends of the core shaft and the stranded wire. A joint is formed so as to join the distal end of the inner flexible tube, the core shaft, and the stranded wire to each other.

Abstract: A rotary type pouch reception/delivery unit is configured to receive a pouch supplied by a pouch supply unit at a pouch reception/delivery position ?, conveys it to a pouch reception/delivery position ?, and delivers it to a spout installation unit at a pouch reception/delivery position ?. The pouch reception/delivery unit is provided with a plurality of take-up members rotating at a constant rotation speed so as to pass the pouch reception/delivery position ? and a pouch reception/delivery position ?. The pouch reception/delivery unit receives the pouch supplied in a standing state at the pouch reception/delivery position ? by sucking and holding it by a take-up member and tilts the pouch during conveyance. At the pouch reception/delivery position ?, the pouch receipt/delivery unit delivers the pouch to the spout installation device with a spout installation edge portion horizontally tilted.

Abstract: A content control system capable of controlling delivery destinations of user contents in respective groups, identifying each group through which each content is delivered, and delivering information/advertisements according to the attribution information of the content. In a content control server, group identifying information is set in each user content to be uploaded to or downloaded from a group memory area corresponding to a gateway ID from a terminal through a gateway having a plurality of its subordinate terminals. The information identifies each gateway through which each object content is delivered according to the gateway ID. The control system controls the delivery destination of each content according to the combination of the content delivery route and a table prepared in the content control server.

Abstract: Score lines are formed on package material. A spout attachment hole is formed in a portion corresponding to a top gusset section of a pouch. A spout is attached to the spout attachment hole. A portion corresponding to a peripheral edge of the top gusset section of the pouch and a portion corresponding to a top edge of a body section of the pouch are heat-sealed, and the package material is cut in the width direction. Portions corresponding to side edges of the body section of the pouch are heat-sealed, and a portion corresponding to a peripheral edge of a bottom gusset section and a portion corresponding to a peripheral edge of a bottom end portion of the body section are heat-sealed. The heat-sealed portions formed at the portions corresponding to the side edges of the body section of the pouch are cut so a spouted pouch package is released.

Abstract: A content recommendation apparatus that can recommend contents suitable to user's taste immediately even after introduction of the system even if a TV set is used by unspecified users. Among previously-determined recommendation ranks of contents, the content recommendation apparatus of the present invention lowers the recommendation rank of a VOD content that is similar to TV programs broadcast in other media at a prescribed time. As the prescribed time, can be employed a time designated by a user, a time on a prescribed cycle, or a time when a TV program on the air in another media is changed, for example.

Abstract: A video-on-demand system in which the plurality of program televising time zones of an identical program is presented to a user beforehand, and the user registers his/her view desiring time zone beforehand. A price which is altered in accordance with the number of simultaneous viewers, and the number of view desiring users are presented to a user. For example, for the pursuit of the profit of an enterpriser, as the number of viewers becomes larger, the price is lowered more to increase the number of viewers still further. On the other hand, the presented price is altered by predetermined rules in order that the viewers may not increase excessively, thereby to lower a program televising quality in excess of the capability of the system. The number of users in a program televising time zone is controlled on an economy principle, whereby the loads of the system is leveled.

Abstract: It is intended to provide a drug to be used in gene therapy which specifically targets abnormal cells such as tumor cells and destroys the same for healing. Namely, a drug comprising, as the active ingredient, a proliferative vector which contains a Survivin promoter proliferating depending on the expression of Survivin. This drug may be used in order to treat tumor. In this drug, use may be made of an adenovirus as the vector. In the adenovirus of this drug, an endogenous promoter of an E1A domain may be substituted with a Survivin promoter.

Abstract: A medical guide wire 1 has a front helical spring 4 which is formed by two stranded wire units 41, 42 in a helically-wired spring configuration in which the two stranded wire units 41, 42 are further twisted in a helically-wired multiple spring configuration. This imparts an increased flexibility to the front helical spring 4, compared to the case in which a front helical spring is formed by a single wire to be diametrically identical to the front helical spring 4. With the favorable flexibility and sufficient torque-transmissibility, it is possible to reduce a risk of having a damage on a blood vessel upon inserting the medical guide wire 1 into the blood vessel.

Abstract: A rotary type pouch reception/delivery unit is configured to receive a pouch supplied by a pouch supply unit at a pouch reception/delivery position ?, conveys it to a pouch reception/delivery position ?, and delivers it to a spout installation unit at a pouch reception/delivery position ?. The pouch reception/delivery unit is provided with a plurality of take-up members rotating at a constant rotation speed so as to pass the pouch reception/delivery position ? and a pouch reception/delivery position ?. The pouch reception/delivery unit receives the pouch supplied in a standing state at the pouch reception/delivery position ? by sucking and holding it by a take-up member and tilts the pouch during conveyance. At the pouch reception/delivery position ?, the pouch receipt/delivery unit delivers the pouch to the spout installation device with a spout installation edge portion horizontally tilted.

Abstract: Provided is a method of preparing a proliferation-regulated recombinant adenoviral vector effectively, comprising preparing a proliferation-regulated vector plasmid by preparing a restriction enzyme-recognizing sequence in a vector plasmid having a proliferation-regulating unit and having an E1A region, a protein-coding region in a E1B region, a poly(A) signal sequence, and a recombinase-recognizing sequence in that order from upstream, by deleting an endogenous promoter in the E1A region or an endogenous promoter regulating expression of the protein-coding gene in one protein-coding region of the E1B region thereof and inserting the restriction enzyme-recognizing sequences in the deficient site, and introducing a promoter expressing specifically in a target organ in the restriction enzyme-recognizing sequence in the restriction enzyme-recognizing sequence; and additionally, integrating the proliferation-regulated vector plasmid into a vector plasmid having a adenoviral genome prepared by deleting the E1 regi

Abstract: The present invention provides a coating method for coating one or more layers on a surface of a continuously moving belt-like substrate. The method includes a cleaning step of maintaining a cleanliness level of class 1000 or less near the substrate before a coating step. According to the present invention, any adhesion of extraneous material, dirt, dust and the like to a continuously moving web or coating layer surface can be prevented to reduce coating defects such as streak development.

Abstract: Provided is a liquid crystal polyester resin composition, which comprises 5-20 parts by weight of glass fiber having a specific number average fiber diameter and fiber length after molding and 100 parts by weight of a specific liquid crystal polyester resin, and the flexural modulus thereof measured with using a test piece of 0.5 mm thickness is 25 GPa or more; and also provided a process for producing a molded article therefrom. The liquid crystal polyester resin composition is low in specific gravity, and is excellent in processability, mechanical properties, and heat resistance.

Abstract: A liquid crystal polyester resin composition having an apparent melt viscosity of 10 to 100 Pa ·sec at a shearing rate of 1000 sec−1 and at a flow temperature +40° C., obtained by compounding 10 to 100 parts by weight of an inorganic filler in the form of fiber and 10 to 100 parts by weight of an inorganic filler in the form of plate based on 100 parts by weight of a liquid crystal polyester resin, wherein the liquid crystal polyester resin contains at least 30% mol of a repeating structural unit of the following formula A1 and has a flow temperature of 270° C. to 400° C., the inorganic filler in the form of fiber has an average fiber diameter of 0.

Abstract: A liquid crystal polyester resin mixture having a stabilized plastication time and accordingly possible to be molded in constant cycles and giving a molded article excellent in mechanical properties and thermal stability is provided. The liquid crystal polyester resin mixture comprises 100 parts by weight of a liquid crystal polyester resin composition which comprises 100 parts by weight of a liquid crystal polyester and from 0 to 150 parts by weight of a filler, and either from 0.001 to 5 parts by weight of a fatty acid amide having a formula; R1—CO—NH2 (wherein R1 denotes a saturated or unsaturated hydrocarbon of 10 to 30 carbons) or from 0.001 to 2 parts by weight of a high molecular weight polyethylene with a molecular weight of 10,000 or higher.

Abstract: The object of the present invention is to provide a liquid crystalline polyester resin composition for connectors that is excellent in fluidity at the time of molding and is therefore capable of producing connectors with further suppressed degree of warpage. The object is achieved by providing a liquid crystalline polyester resin composition for connectors comprising a liquid crystalline polyester resin mixture which comprises a liquid crystalline polyester (A) having a specific flow beginning temperature and a liquid crystalline polyester resin (B) having a specific flow beginning temperature and the flow beginning temperature between the liquid crystalline polyester resin (A) and the liquid crystalline polyester resin (B) is from 20° C. to 60° C., and from 15 to 180 parts by weight of a fibrous and/or plate-shaped inorganic filler; wherein both of the liquid crystalline polyester resin (A) and the liquid crystalline polyester resin (B) are produced by the specific method.