Abstract: The present disclosure generally relates to methods and apparatuses for chemical vapor deposition (CVD) during additive manufacturing (AM) processes. Such methods and apparatuses can be used to embed chemical signatures into manufactured objects, and such embedded chemical signatures may find use in anti-counterfeiting operations and in manufacture of objects with multiple materials.

Abstract: A passive flow modulation device for a machine defining an axial direction and a radial direction, the passive flow modulation device including: a first ring with a first coefficient of thermal expansion; a second ring disposed coaxially with the first ring and positioned at least partially inward of the first ring along the radial direction, spaced from the first ring along the axial direction, or both, the first ring, the second ring, or both defining at least in part one or more passages, the second ring with a second coefficient of thermal expansion that is less than the first coefficient of thermal expansion to passively modulate a size of the one or more passages during operation.

Abstract: A spill-resistant bowl assembly includes a unitary bowl hanger frame, a gimbal mounting, and a bowl. The gimbal mounting has a unitary mounting frame and a gimbal ring. The bowl hanger frame has two parallel inverted “L”-shaped legs joined with a transverse member. The legs have evenly spaced adjustment pegs. The mounting frame has a horizontal member, with keyhole slots connected to the pegs, and arced arms with a socket in each arm. The ring has diametrically opposed pegs on a first axis and diametrically opposed notches along a second axis perpendicular to the first axis; with the ring pegs connected to the sockets. The bowl has a rim with diametrically opposed pegs connected to the notches. The travel bowl assembly may be suspended from a car seat headrest so a dog has easy access to water at a comfortable height without spilling.

Abstract: The embodiments of present invention provide processes and an intermediate for the large-scale preparation of 2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)-2-pyridyl]benzamide hemisuccinate, and formulations and product forms made by these processes. The embodiments of the present invention further provide for the preparation of lasmiditan acetate, 2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)-2-pyridyl]benzamide acetate salt, and/or pharmaceutical compositions thereof, and/or uses of lasmiditan acetate and formulations thereof in subcutaneous drug delivery.

Abstract: Provided herein are proteins comprising one monovalent human TfR binding domain (“human TfR binding proteins”), proteins comprising one monovalent mouse TfR binding domain (“mouse TfR binding proteins”), conjugates comprising such human or mouse TfR binding proteins, e.g., human TfR binding proteins-dsRNA conjugates, pharmaceutical compositions comprising human TfR binding proteins or conjugates, and methods of treating CNS diseases (e.g., neurodegenerative disease such as neurodegenerative synucleinopathy or tauopathy) using human TfR binding proteins or conjugates.

Abstract: A gas turbine engine includes: a turbomachine including a combustion section and an exhaust assembly arranged in serial flow order; and a fuel system. The fuel system includes: a hydrogen fuel tank for holding a hydrogen fuel in a liquid phase; and a hydrogen delivery assembly in thermal communication with the exhaust assembly. The hydrogen delivery assembly includes: a liquid hydrogen line in fluid communication with the hydrogen fuel tank; a gaseous hydrogen line in fluid communication with the combustion section of the gas turbine engine; and a heat exchanger tubing positioned within the exhaust assembly downstream of the liquid hydrogen line and upstream of the gaseous hydrogen line.

Abstract: Systems and methods for facilitating the sorting of assets to sort locations. In various embodiments, a sort employee scans an asset indicia using a user device, which stores asset data corresponding to the stored asset. As the sort employee nears a sort location (e.g., a delivery vehicle) with the asset and the user device, the user device automatically communicates wirelessly with a sort location receiver to associate the asset data with data indicative of the sort location where the user deposits the asset. In various embodiments, a device may determine whether the user device is proximate the appropriate sort location for the item, and may generate an alert upon a determination that the user device is proximate an incorrect sort location.

Abstract: A system and method for automating workflow and performing root cause analysis for enforcement events is presented. The system can enable accurate detection of an enforcement event and identifies the root cause of such events. The system can provide a user with an interface to monitor the enforcement event by collecting a list of data characterizing the enforcement event, as well as analyze the data to evaluate what is the root cause of the enforcement event. The system can extract critical information from train system logs of the train using an extraction model to generate a window of activity providing an analysis model with a comprehensive scope to analyze the enforcement event. The system can give the user robust and accurate information of the root cause of the enforcement event.

Abstract: A fuel system for a gas turbine engine is provided. The gas turbine engine including an exhaust assembly. The exhaust assembly including a tail cone and defining a radial direction, a circumferential direction, an axial direction, a working gas flow path, and an outer bypass flow path, the fuel system including: a hydrogen fuel tank for holding a hydrogen fuel; a heat exchanger configured to be coupled to or integrated into the tail cone of the exhaust assembly, the heat exchanger including: a first axial flow path in flow communication with the hydrogen fuel tank; a second axial flow path in flow communication with a combustion section of the gas turbine engine; and a radial flow path.

Abstract: The present invention relates to the field of prognostic of lung cancer. In this study, the inventors used extensive gene expression profiling and flow cytometry for an integrative analysis of the phenotypes of the B cells and CD4+ T cells from tumors and blood of NSCLC patients by TLS-B density. They showed that TIL B cells and TIL CD4+ T cells are more highly activated in tumors than in the periphery and that they express all the ligand/receptor pairs necessary for B/T interactions and two-way co-stimulation. Moreover, a high density of TLS-B cells is associated with higher frequencies of activated CD4+ T cells and lower frequencies of both immune checkpoint (ICP)-expressing CD4+ T cells and regulatory CD4+ T cells (Tregs) in the intratumor CD4+ T cell compartment. High densities of TLS-B cells together with low densities of FoxP3+ CD3+ Tregs in NSCLC tumors consistently identified the group of patients with the best clinical outcome.

Abstract: A rotary machine includes a stator and a rotor configured to rotate with respect to the stator. The rotor is arranged with the stator at a rotor-stator interface and defines a rotor face. Further, the rotary machine includes a seal assembly at the rotor-stator interface. The seal assembly includes at least one seal and a groove formed into the rotor at the rotor-stator interface. In addition, the seal assembly includes a removable insert positioned within the groove of the seal assembly and defining at least a portion of the rotor face. As such, during operation of the rotary machine, if the rotor and the stator make undesirable contact at the rotor-stator interface, the removable insert becomes damaged to prevent damage from occurring to the rotor and the stator.

Abstract: The invention relates to systems and methods of revealing portions of outcomes of real-world wagers through interactive media by storing reserve wagers, receiving an indication a first token has been acquired by a user, determining a tracking wager associated with the first token, matching a stored reserve wager with the tracking wager, associating the matched reserve wager with the first token, and revealing at least a portion of the outcome of the matched reserve wager to the user by the user's interaction with the interactive media. By integrating real-world wager outcomes with user interactions, the system may provide an engaging user experience with interactive media. For example, a game may reveal an outcome of a real-world wager (which has already occurred), in response to in-game actions such as user actions in the game, other players' actions, game events, and/or other events.

Abstract: A gas turbine engine having a compressor section, a combustion section, and a turbine section in serial flow arrangement to define a diffuser cavity between the compressor section and the combustor section, and an aft cavity. A compressor discharge pressure duct fluidly draws air from the diffuser cavity, passes it through a heat exchanger to cool the air, and then supplies the cooled air to the aft cavity.

Abstract: A gas turbine engine including a compressor section including a compressor and a turbine section located downstream of the compressor section. The turbine section including a high pressure turbine, a low pressure turbine, a sump positioned between the high pressure turbine and the low pressure turbine, and a rotating cross flow arrangement defining a plurality of guiding passages fluidly coupling the compressor to the sump.

Abstract: A fuel vapor recirculation system includes a filler neck adapted to receive a refueling nozzle that dispenses fuel into the filler neck. A fuel tank receives fuel from the filler neck through an inlet check valve. The check valve is disposed in the fuel inlet opening and is normally closed. The check valve opens when fuel is dispensed into the fuel tank. The check valve defines a vent hole that is always open. The fuel tank also includes a fuel limiting vent valve and a grade limit vent valve. A fuel vapor cannister collects fuel vapor and selectively supplies fuel vapor to an intake manifold of a vehicle. The fuel vapor recirculation manifold receives fuel vapor only from the fuel limiting vent valve and the grade limit vent valve in the fuel tank and does not receive fuel vapor directly from the filler neck.

Abstract: A seal assembly at a rotor-stator interface includes at least one non-contacting seal interface and at least one rub detection feature. The rub detection feature(s) is configured to generate a signal upon the rotor and the stator making contact at the rotor-stator interface and causing wear above a certain threshold at the rotor-stator interface. The seal assembly also includes at least one sensor arranged at the rotor-stator interface. The sensor is configured to sense the signal. The seal assembly further includes a controller communicatively coupled with the sensor(s). The controller is configured to receive the signal and estimate at least one of an amount and a location of the wear at the rotor-stator interface based on the signal.

Abstract: Adjustable fire protection assemblies and methods are provided. The assembly includes a sprinkler having a body with an outer encasing surface and a deflector supported from the body. An escutcheon having a receiver and a rim surround the fire protection sprinkler to define an aperture between the receiver and the sprinkler. A push-to-connect fitting of the assembly includes a tubular member with an end for connection to a pipe and an internal conduit that receives the sprinkler body. A seal member and a retaining ring are disposed within the tubular member to form an adjustable seal and grip about the sprinkler body. A releasing member translates to disengage the retaining ring from the sprinkler body; and the escutcheon translates with respect to the tubular member in a sliding surface engagement to define an adjustable deflector-to-rim distance between the rim of the escutcheon and the deflector of the sprinkler.

Abstract: Hardened target sensors and systems are described herein. An example system includes a projectile defining an ogive, a body, and a base. The body of the projectile is arranged between the ogive and the base. The system includes a sensor assembly including a nose member and a plurality of strain gauges. The nose member defines a nose portion, a shaft, portion, and a threaded portion. The strain gauges are attached to the shaft portion. The system includes a shroud member, which is mechanically coupled with the sensor assembly and the body. The system further includes a smart fuze arranged within the body. The smart fuze is operably coupled to the strain gauges. The strain gauges measure the compression/tension of the shaft portion, which is part of the nose member. The load measured by the strain gauges can be used to detect hardened target layers and/or voids.

Abstract: A method of operating a fuel management unit for a fuel system. The method including: receiving data indicative of a state of an exhaust assembly using a sensor of the fuel system, the state of the exhaust assembly including a temperature of a working gas flow within the exhaust assembly; determining an amount of a hydrogen fuel in a liquid phase to provide to a hydrogen delivery assembly in response to receiving data indicative of the state of the exhaust assembly; and directing one or more components to provide the determined amount of the hydrogen fuel to the hydrogen delivery assembly.

Abstract: A method of making an electrocaloric article is disclosed. The method includes mounting a supported electrocaloric film to a frame. The supported electrocaloric film includes an electrocaloric film and a first support film disposed on a first side of the electrocaloric film. An active area of the electrocaloric film is provided, which is not covered by the first support film on the first side of the electrocaloric film. Electrical connections are provided to electrodes disposed on opposing sides of the electrocaloric film in the active area.